Projects per year
Personal profile
Biography
Position
Senior Lecturer
Faculty of Pharmacy and Pharmaceutical Sciences
Medicinal Chemistry
Monash Institute of Pharmaceutical Sciences
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Drug Design
- Computational Chemistry
- Medicinal Chemistry
- Fragment Based Drug Design
- Molecular Dynamics
- Pharmaceutical Sciences
- Peptide Chemistry
- Nano-Materials
- HIV
- anti-infective agents
- anti-viral drugs
- Molecular Modeling
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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alpha1-adrenoceptor protein structures and selective tools: towards novel treatments for heart failure and Alzheimer’s disease
Scott, D. J., Abdul Ridha, A., Chalmers, D., Draper-Joyce, C., Gooley, P., Adlard, P. A., Lankadeva, Y. R., Betrie, A. H., Graham, B. & Thal, D.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/22 → 31/12/25
Project: Research
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New strategy to safely and effectively reduce diabetic kidney disease
Chai, Z., Chalmers, D. & Cooper, M.
1/01/22 → 31/12/25
Project: Research
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Australasian Computational and Simulation Commons
Mark, A. E., Chalmers, D., Sroet, M., Bernhardt, D., Krenske, E. H., Mancera, R., O'Mara, M. L., Yu, H., Pas, E., Goerigk, L., Deplazes, E., Malde, A., Smith, B. & Haung, D.
30/06/21 → 31/12/22
Project: Research
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Resolving and targeting the complex molecular mechanisms underlying GPCR signalling
Bathgate, R. A. D., Scott, D. J., Gooley, P. R., Griffith, M., Chalmers, D. & Hubbard, R.
1/01/18 → 31/12/21
Project: Research
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Targeting novel sites on reverse transcriptase for HIV treatment and prevention
Tachedjian, G., Chalmers, D., Sluis-Cremer, N., Arnold, E., Thompson, P., Headey, S. & Latham, C. F. M.
1/01/17 → 31/12/19
Project: Research
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Interaction of the Inhibitory Peptides ShK and HmK with the Voltage-Gated Potassium Channel KV1.3: Role of Conformational Dynamics
Sanches, K., Prypoten, V., Chandy, K. G., Chalmers, D. K. & Norton, R. S., 4 May 2023, In: Journal of Chemical Information and Modeling. 63, 10, p. 3043–3053 11 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Molecular Dynamics Simulation Studies of Bile, Bile Salts, Lipid-Based Drug Formulations, and mRNA-Lipid Nanoparticles: A Review
Guruge, A. G., Warren, D. B., Pouton, C. W. & Chalmers, D. K., 17 May 2023, In: Molecular Pharmaceutics. 20, 6, p. 2781-2800 20 p.Research output: Contribution to journal › Review Article › Research › peer-review
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Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach
Mansouri, M., Rumrill, S., Dawson, S., Johnson, A., Pinson, J. A., Gunzburg, M. J., Latham, C. F., Barlow, N., Mbogo, G. W., Ellenberg, P., Headey, S. J., Sluis-Cremer, N., Tyssen, D., Bauman, J. D., Ruiz, F. X., Arnold, E., Chalmers, D. K. & Tachedjian, G., Apr 2023, In: Molecules. 28, 7, 26 p., 3103.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Targeting Melanocortin Receptors Using SNAr-Type Macrocyclization: A Doubly Orthogonal Route to Cyclic Peptide Conjugates
Yue, W. K., Zhang, T., Shandre Mugan, R., Barlow, N., Chalmers, D. K., Pouton, C. W. & Thompson, P. E., 21 Feb 2023, In: Journal of Medicinal Chemistry. 66, 5, p. 3273-3283 11 p.Research output: Contribution to journal › Article › Research › peer-review
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Crystal structure of the α1B-adrenergic receptor reveals molecular determinants of selective ligand recognition
Deluigi, M., Morstein, L., Schuster, M., Klenk, C., Merklinger, L., Cridge, R. R., de Zhang, L. A., Klipp, A., Vacca, S., Vaid, T. M., Mittl, P. R. E., Egloff, P., Eberle, S. A., Zerbe, O., Chalmers, D. K., Scott, D. J. & Plückthun, A., Dec 2022, In: Nature Communications. 13, 13 p., 382.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus)
Activities
- 1 Submissions to industry or govt committees, commissions and inquiries
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Medicinal Chemistry
David Chalmers (Member)
1 Aug 2013Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries