Darren Henstridge

Mr

20082019
If you made any changes in Pure these will be visible here soon.

Research Output 2008 2019

2019

Metabolic control and sex: A focus on inflammatory-linked mediators

Henstridge, D. C., Abildgaard, J., Lindegaard, B. & Febbraio, M. A., 28 Feb 2019, (Accepted/In press) In : British Journal of Pharmacology. 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance

Brandon, A. E., Liao, B. M., Diakanastasis, B., Parker, B. L., Raddatz, K., McManus, S. A., O'Reilly, L., Kimber, E., van der Kraan, A. G., Hancock, D., Henstridge, D. C., Meikle, P. J., Cooney, G. J., James, D. E., Reibe, S., Febbraio, M. A., Biden, T. J. & Schmitz-Peiffer, C., 8 Jan 2019, In : Cell Metabolism. 29, 1, p. 183-191 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production

Hu, M., Schulze, K. E., Ghildyal, R., Henstridge, D. C., Kolanowski, J. L., New, E. J., Hong, Y., Hsu, A. C., Hansbro, P. M., Wark, P. A., Bogoyevitch, M. A. & Jans, D. A., 27 Jun 2019, In : eLife. 8, 30 p., e42448.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2018

APP deficiency results in resistance to obesity but impairs glucose tolerance upon high fat feeding

Czeczor, J. K., Genders, A. J., Aston-Mourney, K., Connor, T., Hall, L. G., Hasebe, K., Ellis, M., De Jong, K. A., Henstridge, D. C., Meikle, P. J., Febbraio, M. A., Walder, K. & McGee, S. L., 1 Jun 2018, In : Journal of Endocrinology. 237, 3, p. 311-322 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Evidence against a role for NLRP3-driven islet inflammation in db/db mice

Kammoun, H. L., Allen, T. L., Henstridge, D. C., Barre, S., Coll, R. C., Lancaster, G. I., Cron, L., Reibe, S., Chan, J. Y., Bensellam, M., Laybutt, D. R., Butler, M. S., Robertson, A. A. B., O'Neill, L. A., Cooper, M. A. & Febbraio, M. A., 1 Apr 2018, In : Molecular Metabolism. 10, p. 66-73 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Skeletal muscle-specific overexpression of heat shock protein 72 improves skeletal muscle insulin-stimulated glucose uptake but does not alter whole body metabolism

Marshall, J. P. S., Estevez, E., Kammoun, H. L., King, E. J., Bruce, C. R., Drew, B. G., Qian, H., Iliades, P., Gregorevic, P., Febbraio, M. A. & Henstridge, D. C., 1 Aug 2018, In : Diabetes, Obesity and Metabolism. 20, 8, p. 1928-1936 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Corrigendum: 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function

Schoenwaelder, S. M., Darbousset, R., Cranmer, S. L., Ramshaw, H. S., Orive, S. L., Sturgeon, S., Yuan, Y., Yao, Y., Krycer, J. R., Woodcock, J., Maclean, J., Pitson, S., Zheng, Z., Henstridge, D. C., van der Wal, D., Gardiner, E. E., Berndt, M. C., Andrews, R. K., James, D. E., Lopez, A. F. & 1 others, Jackson, S. P., 30 Aug 2017, In : Nature Communications. 8, 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
File

High-density lipoprotein delivered after myocardial infarction increases cardiac glucose uptake and function in mice

Heywood, S. E., Richart, A. L., Henstridge, D. C., Alt, K., Kiriazis, H., Zammit, C., Carey, A. L., Kammoun, H. L., Delbridge, L. M., Reddy, M., Chen, Y. C., Du, X. J., Hagemeyer, C. E., Febbraio, M. A., Siebel, A. L. & Kingwell, B. A., 11 Oct 2017, In : Science Translational Medicine. 9, 411, 10 p., eaam6084.

Research output: Contribution to journalArticleResearchpeer-review

Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects

Keshvari, S., Henstridge, D. C., Ng, C., Febbraio, M. A. & Whitehead, J. P., 1 Feb 2017, In : Scientific Reports. 7, 13 p., 41792.

Research output: Contribution to journalArticleResearchpeer-review

Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice

Kammoun, H. L., Allen, T. L., Henstridge, D. C., Kraakman, M. J., Peijs, L., Rose-John, S. & Febbraio, M. A., 20 Jun 2017, In : PLoS ONE. 12, 6, 13 p., e0179099.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice

Gaur, V., Connor, T., Venardos, K., Henstridge, D. C., Martin, S. D., Swinton, C., Morrison, S., Aston-Mourney, K., Gehrig, S. M., van Ewijk, R., Lynch, G. S., Febbraio, M. A., Steinberg, G. R., Hargreaves, M., Walder, K. R. & McGee, S. L., 1 Jul 2017, In : Diabetes, Obesity and Metabolism. 19, 7, p. 936-943 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Transcription Factor IRF4 Promotes CD8+ T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection

Man, K., Gabriel, S. S., Liao, Y., Gloury, R., Preston, S., Henstridge, D. C., Pellegrini, M., Zehn, D., Berberich-Siebelt, F., Febbraio, M. A., Shi, W. & Kallies, A., 19 Dec 2017, In : Immunity. 47, 6, p. 1129-1141 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2016

14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function

Schoenwaelder, S. M., Darbousset, R., Cranmer, S. L., Ramshaw, H. S., Orive, S. L., Sturgeon, S., Yuan, Y., Yao, Y., Krycer, J. R., Woodcock, J. M., Maclean, J., Pitson, S., Zheng, Z., Henstridge, D. C., Van Der Wal, D., Gardiner, E. E., Berndt, M. C., Andrews, R. K., James, D. E., Lopez, A. F. & 1 others, Jackson, S. P., 27 Sep 2016, In : Nature Communications. 7, 17 p., 12862.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism

Chaurasia, B., Kaddai, V. A., Lancaster, G. I., Henstridge, D. C., Sriram, S., Galam, D. L. A., Gopalan, V., Prakash, K. N. B., Velan, S. S., Bulchand, S., Tsong, T. J., Wang, M., Siddique, M. M., Yuguang, G., Sigmundsson, K., Mellet, N. A., Weir, J. M., Meikle, P. J., Bin M. Yassin, M. S., Shabbir, A. & 5 others, Shayman, J. A., Hirabayashi, Y., Shiow, S-A. T. E., Sugii, S. & Summers, S. A., 13 Dec 2016, In : Cell Metabolism. 24, 6, p. 820-834 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Deficiency in apoptosis-inducing factor recapitulates chronic kidney disease via aberrant mitochondrial homeostasis

Coughlan, M. T., Higgins, G. C., Nguyen, T-V., Penfold, S. A., Thallas-Bonke, V., Tan, S. M., Ramm, G., Van Bergen, N. J., Henstridge, D. C., Sourris, K. C., Harcourt, B. E., Trounce, I. A., Robb, P. M., Laskowski, A., McGee, S. L., Genders, A. J., Walder, K., Drew, B. G., Gregorevic, P., Qian, H. & 13 others, Thomas, M. C., Jerums, G., Macisaac, R. J., Skene, A., Power, D. A., Ekinci, E. I., Wijeyeratne, X. W., Gallo, L. A., Herman-Edelstein, M., Ryan, M. T., Cooper, M. E., Thorburn, D. R. & Forbes, J. M., Apr 2016, In : Diabetes. 65, 4, p. 1085-1098 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation

Gaur, V., Connor, T., Sanigorski, A., Martin, S. D., Bruce, C. R., Henstridge, D. C., Bond, S. T., McEwen, K. A., Kerr-Bayles, L., Ashton, T. D., Fleming, C. L., Wu, M., Pike Winer, L. S., Chen, D., Hudson, G. M., Schwabe, J. W. R., Baar, K., Febbraio, M. A., Gregorevic, P., Pfeffer, F. M. & 3 others, Walder, K. R., Hargreaves, M. & McGee, S. L., 13 Sep 2016, In : Cell Reports. 16, 11, p. 2802-2810 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Emerging role and characterization of immunometabolism: Relevance to HIV pathogenesis, serious non-AIDS events, and a cure

Palmer, C. S., Henstridge, D. C., Yu, D., Singh, A., Balderson, B., Duette, G., Cherry, C. L., Anzinger, J. J., Ostrowski, M. & Crowe, S. M., 1 Jun 2016, In : Journal of Immunology. 196, 11, p. 4437-4444 8 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Heat shock proteins and exercise adaptations. Our knowledge thus far and the road still ahead

Henstridge, D. C., Febbraio, M. A. & Hargreaves, M., 15 Mar 2016, In : Journal of Applied Physiology. 120, 6, p. 683-691 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

High fat diet inhibits dendritic cell and T cell response to allergens but does not impair inhalational respiratory tolerance

Pizzolla, A., Oh, D. Y., Luong, S., Prickett, S. R., Henstridge, D. C., Febbraio, M. A., O'Hehir, R. E., Rolland, J. M. & Hardy, C. L., 1 Aug 2016, In : PLoS ONE. 11, 8, 18 p., e0160407.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity

Cropley, J. E., Eaton, S. A., Aiken, A., Young, P. E., Giannoulatou, E., Ho, J. W. K., Buckland, M. E., Keam, S. P., Hutvagner, G., Humphreys, D. T., Langley, K. G., Henstridge, D. C., Martin, D. I. K., Febbraio, M. A. & Suter, C. M., 1 Aug 2016, In : Molecular Metabolism. 5, 8, p. 699-708 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2015

Analysis of the liver lipidome reveals insights into the protective effect of exercise on high-fat diet-induced hepatosteatosis in mice

Jordy, A. B., Kraakman, M. J., Gardner, T., Estevez, E., Kammoun, H. L., Weir, J. M., Kiens, B., Meikle, P. J., Febbraio, M. A. & Henstridge, D. C., May 2015, In : American Journal of Physiology - Endocrinology and Metabolism. 308, 9, p. E778-E791 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance

Kraakman, M. J., Kammoun, H. L., Allen, T. L., Deswaerte, V., Henstridge, D. C., Estevez, E., Matthews, V. B., Neill, B. A., White, D. A., Murphy, A. J., Peijs, L., Yang, C., Risis, S., Bruce, C. R., Du, X-J., Bobik, A., Lee-Young, R. S., Kingwell, B. A., Vasanthakumar, A., Shi, W. & 4 others, Kallies, A., Lancaster, G. I., Rose-John, S. & Febbraio, M. A., 3 Mar 2015, In : Cell Metabolism. 21, 3, p. 403-416 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance

Henstridge, D. C., Estevez, E., Allen, T. L., Heywood, S. E., Gardner, T., Yang, C., Mellett, N. A., Kingwell, B. A., Meikle, P. J. & Febbraio, M. A., 1 May 2015, In : Cell Stress and Chaperones. 20, 3, p. 461-472 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Nanoporous metal-phenolic particles as ultrasound imaging probes for hydrogen peroxide

Guo, J., Wang, X., Henstridge, D. C., Richardson, J. J., Cui, J., Sharma, A., Febbraio, M. A., Peter, K., De Haan-Klein, J. B., Hagemeyer, C. E. & Caruso, F., 2015, In : Advanced Healthcare Materials. 4, 14, p. 2170 - 2175 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin resistance

Henstridge, D. C., Bruce, C. R., Drew, B. G., Tory, K., Kolonics, A., Estevez, E., Chung, J., Watson, N., Gardner, T., Lee-Young, R. S., Connor, T., Watt, M. J., Carpenter, K., Hargreaves, M., McGee, S. L., Hevener, A. & Febbraio, M. A., 2014, In : Diabetes. 63, 6, p. 1881 - 1894 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Chaperoning to the metabolic party: The emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetes

Henstridge, D. C., Whitham, M. & Febbraio, M. A., 1 Nov 2014, In : Molecular Metabolism. 3, 8, p. 781-793 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Erratum: The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells (Nature Immunology (2013) 14 (1155-1165 ))

Man, K., Miasari, M., Shi, W., Xin, A., Henstridge, D. C., Preston, S. P., Pellegrini, M., Belz, G. T., Smyth, G. K., Febbraio, M. A., Nutt, S. L. & Kallies, A., 2014, In : Nature Immunology. 15, 9, p. 894 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection

Palmer, C. P-S., Ostrowski, M., Gouillou, M., Tsai, L. M-C., Yu, D., Zhou, J., Henstridge, D. C., Maisa, A., Hearps, A. C., Lewin, S. R., Landay, A. L., Jaworowski, A., McCune, J. M. & Crowe, S. M., 2014, In : AIDS. 28, 3, p. 297 - 309 13 p.

Research output: Contribution to journalArticleResearchpeer-review

The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice

Sapra, G., Tham, Y. K., Cemerlang, N., Matsumoto, A., Kiriazis, H., Bernardo, B. C., Henstridge, D. C., Ooi, J. Y. Y., Pretorius, L., Boey, E. J. H., Lim, L., Sadoshima, J., Meikle, P. J., Mellett, N. A., Woodcock, E. A., Marasco, S., Ueyama, T., Du, X-J., Febbraio, M. A. & McMullen, J. R., 2014, In : Nature Communications. 5, p. 1 - 16 16 p., 5705.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2013

Ceramides contained in LDL are elevated in type 2 diabetes and promote inflammation and skeletal muscle insulin resistance

Boon, J. Y. C., Hoy, A. J., Stark, R., Brown, R. D., Meex, R. CR., Henstridge, D. C., Schenk, S., Meikle, P. J., Horowitz, J. F., Kingwell, B. A., Bruce, C. & Watt, M. J., 2013, In : Diabetes. 62, 2, p. 401 - 410 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

Turner, N., Kowalski, G., Leslie, S. J., Risis, S., Yang, C., Lee-Young, R. S., Babb, J. R., Meikle, P. J., Lancaster, G. I., Henstridge, D. C., White, P. J., Kraegen, E. W., Marette, A., Cooney, G. J., Febbraio, M. A. & Bruce, C., 2013, In : Diabetologia. 56, 7, p. 1638 - 1648 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Maternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic mice

Li, C. C. Y., Young, P. E., Maloney, C. A., Eaton, S. A., Cowley, M. J., Buckland, M. E., Preiss, T., Henstridge, D. C., Cooney, G. J., Febbraio, M. A., Martin, D. I. K., Cropley, J. E. & Suter, C. M., 1 Jun 2013, In : Epigenetics. 8, 6, p. 602-611 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

p32 protein levels are integral to mitochondrial and endoplasmic reticulum morphology, cell metabolism and survival

Hu, M., Crawford, S. A., Henstridge, D. C., Ng, I. H. W., Boey, E. JH., Xu, Y., Febbraio, M. A., Jans, D. A. & Bogoyevitch, M. A., 2013, In : Biochemical Journal. 453, 3, p. 381-391 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells

Man, K., Miasari, M., Shi, W., Xin, A., Henstridge, D. C., Preston, S. P., Pellegrini, M., Belz, G. T., Smyth, G. K., Febbraio, M. A., Nutt, S. L. & Kallies, A., 2013, In : Nature Immunology. 14, 11, p. 1155-1165 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

Enhanced phosphoinositide 3-kinase(p110α) activity prevents diabetes-induced cardiomyopathy and superoxide generation in a mouse model of diabetes

Ritchie, R. H., Love, J. E., Huynh, K., Bernardo, B. C., Henstridge, D. C., Kiriazis, H., Tham, Y. K., Sapra, G., Qin, C., Cemerlang, N., Boey, E. J. H., Jandeleit-Dahm, K., Du, X. J. & McMullen, J. R., Dec 2012, In : Diabetologia. 55, 12, p. 3369-3381 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

Gehrig, S. M., van der Poel, C., Sayer, T. A., Schertzer, J. D., Henstridge, D. C., Church, J. E., Lamon, S., Russell, A. P., Davies, K. E., Febbraio, M. A. & Lynch, G. S., 19 Apr 2012, In : Nature. 484, 7394, p. 394-398 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Myeloid-specific estrogen receptor α deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 39 (16457-16462) 10.1073/pnas.1104533108)

Ribas, V., Drew, B. G., Le, J. A., Soleymani, T., Daraei, P., Sitz, D., Mohammad, L., Henstridge, D. C., Febbraio, M. A., Hewitt, S. C., Korach, K. S., Bensinger, S. J. & Andrea, L., 10 Jan 2012, In : Proceedings of the National Academy of Sciences. 109, 2, p. 645 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice

Henstridge, D. C., Bruce, C. R., Pang, C. P., Lancaster, G. I., Allen, T. L., Estevez, E., Gardner, T., Weir, J. M., Meikle, P. J., Lam, K. S. L., Xu, A., Fujii, N., Goodyear, L. J. & Febbraio, M. A., 2012, In : Diabetologia. 55, 10, p. 2769 - 2778 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Myeloid-specific estrogen receptor α deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development

Ribas, V., Drew, B. G., Le, J. A., Soleymani, T., Daraei, P., Sitz, D., Mohammad, L., Henstridge, D. C., Febbraio, M. A., Hewitt, S. C., Korach, K. S., Bensinger, S. J. & Hevener, A. L., 27 Sep 2011, In : Proceedings of the National Academy of Sciences. 108, 39, p. 16457-16462 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2010

Adiponectin sparks an interest in calcium

Henstridge, D. C. & Febbraio, M. A., 9 Jun 2010, In : Cell Metabolism. 11, 6, p. 447-449 3 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

2009

High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus

Drew, B. G., Duffy, S. J., Formosa, M., Natoli, A. K., Henstridge, D. C., Penfold, S. A., Thomas, W. G., Mukhamedova, N., de Courten, B., Forbes, J., Yap, F., Kaye, D. M., van Hall, G., Febbraio, M., Kemp, B., Sviridov, D., Steinberg, G. R. & Kingwell, B. A., 2009, In : Circulation. 119, 15, p. 2103 - 2111 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Oral nitrate therapy does not affect glucose metabolism in healthy men

Henstridge, D. C., Duffy, S. J., Formosa, M. F., Ahimastos, A. A., Thompson, B. R. & Kingwell, B. A., Nov 2009, In : Clinical and Experimental Pharmacology and Physiology. 36, 11, p. 1086-1092 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The effect of the nitric oxide donor sodium nitroprusside on glucose uptake in human primary skeletal muscle cells

Henstridge, D. C., Drew, B. G., Formosa, M., Natoli, A. K., Cameron-Smith, D., Duffy, S. J. & Kingwell, B. A., 2009, In : Nitric Oxide-Biology and Chemistry. 21, 2, p. 126 - 131 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2008

HSP72 protects against obesity-induced insulin resistance

Chung, J., Nguyen, A-K., Henstridge, D. C. C., Holmes, A. G., Chan, S. M. H., Mesa, J. L., Lancaster, G. I. I., Southgate, R. J. J., Bruce, C. R., Duffy, S. J. J., Horvath, I., Mestril, R., Watt, M. J. J., Hooper, P. L., Kingwell, B. A. A., Vigh, L., Hevener, A. & Febbraio, M. A., 2008, In : Proceedings of the National Academy of Sciences. 105, 5, p. 1739 - 1744 6 p.

Research output: Contribution to journalArticleResearchpeer-review