Daniella Brasacchio

Dr

20052018
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Research Output 2005 2018

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2018

Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer

Brasacchio, D., Busuttil, R. A., Noori, T., Johnstone, R. W., Boussioutas, A. & Trapani, J. A., 1 Jan 2018, In : Cell Death and Disease. 9, 5, 10 p., 442.

Research output: Contribution to journalArticleResearchpeer-review

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2017

Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization

Brasacchio, D., Alsop, A. E., Noori, T., Lufti, M., Iyer, S., Simpson, K. J., Bird, P. I., Kluck, R. M., Johnstone, R. W. & Trapani, J. A., 2017, In : Cell Death and Differentiation. 24, p. 961-970 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage

Brasacchio, D., Noori, T., House, C. M., Brennan, A. J., Simpson, K. J., Susanto, O., Bird, P. I., Johnstone, R. W. & Trapani, J. A., 2014, In : Cell Death and Differentiation. 21, 5, p. 748 - 760 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis

Susanto, O., Stewart, S. E., Voskoboinik, I., Brasacchio, D., Hagn, M., Ellis, S. L., Asquith, S., Sedelies, K. A., Bird, P. I., Waterhouse, N. J. & Trapani, J. A., 2013, In : Cell Death and Differentiation. 20, 9, p. 1183 - 1193 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

Controversies in granzyme biology

Susanto, O., Trapani, J. A. & Brasacchio, D., Dec 2012, In : Tissue Antigens. 80, 6, p. 477-487 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Delayed intervention with AGE inhibitors attenuates the progression of diabetes-accelerated atherosclerosis in diabetic apolipoprotein E knockout mice

Watson, A., Soro-Paavonen, A., Sheehy, K., Li, J., Calkin, A. C., Koitka, A., Rajan, S. N., Brasacchio, D., Allen, T. J., Cooper, M. E., Thomas, M. C. & Jandeleit-Dahm, K. J. A., Mar 2011, In : Diabetologia. 54, 3, p. 681-689 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase

Soro-Paavonen, A., Zhang, W. Z., Venardos, K., Coughlan, M. T., Harris, E., Tong, D. C. K., Brasacchio, D., Paavonen, K., Chin-Dusting, J., Cooper, M. E., Kaye, D., Thomas, M. C. & Forbes, J. M., Apr 2010, In : Journal of Hypertension. 28, 4, p. 780-788 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail

Brasacchio, D., Okabe, J., Tikellis, C., Balcerczyk, A., George, P., Baker, E. K., Calkin, A. C., Brownlee, M., Cooper, M. E. & El-Osta, A., May 2009, In : Diabetes. 58, 5, p. 1229-1236 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2008

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

El-Osta, A., Brasacchio, D., Yao, D., Pocai, A., Jones, P. L., Roeder, R. G., Cooper, M. E. & Brownlee, M., 29 Sep 2008, In : Journal of Experimental Medicine. 205, 10, p. 2409-2417 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing

Harikrishnan, K. N., Chow, M. Z., Baker, E. K., Pal, S., Bassal, S., Brasacchio, D., Wang, L., Craig, J. M., Jones, P. L., Sif, S. & El-Osta, A., 2005, In : Nature Genetics. 37, 3, p. 254-264 11 p.

Research output: Contribution to journalArticleResearchpeer-review