Daniella Brasacchio

Dr

20052018
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Personal profile

Biography

Dr Daniella Brasacchio is a Research Fellow in the Blood Cancer Therapeutics laboratory within the School of Clinical Sciences. The laboratory focuses on translational work incorporating epigenetic drugs with immunotherapy in haematological cancers, particularly lymphoma and multiple myeloma. This research aims to facilitate bench-to-bedside research in order to progress these new treatments into the haematology clinic.  

Research interests

Blood Cancers

Cell Biology

Cancer

Epigenetics

 

Education/Academic qualification

Science, Bachelor, Honours, MONASH UNIVERSITY

1 Mar 199920 Dec 2004

External positions

Research Fellow, Peter MacCallum Cancer Centre

1 Sep 200910 Oct 2015

Project Manager, Centre of Cardiovascular Research and Education in Therapeutics, Monash University

4 Jan 200925 Aug 2009

Research Fellow, Baker Heart and Diabetes Institute

1 Jan 200820 Dec 2008

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Research Output 2005 2018

2 Citations (Scopus)

Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer

Brasacchio, D., Busuttil, R. A., Noori, T., Johnstone, R. W., Boussioutas, A. & Trapani, J. A., 1 Jan 2018, In : Cell Death and Disease. 9, 5, 10 p., 442.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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38 Citations (Scopus)

Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization

Brasacchio, D., Alsop, A. E., Noori, T., Lufti, M., Iyer, S., Simpson, K. J., Bird, P. I., Kluck, R. M., Johnstone, R. W. & Trapani, J. A., 2017, In : Cell Death and Differentiation. 24, p. 961-970 10 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage

Brasacchio, D., Noori, T., House, C. M., Brennan, A. J., Simpson, K. J., Susanto, O., Bird, P. I., Johnstone, R. W. & Trapani, J. A., 2014, In : Cell Death and Differentiation. 21, 5, p. 748 - 760 13 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis

Susanto, O., Stewart, S. E., Voskoboinik, I., Brasacchio, D., Hagn, M., Ellis, S. L., Asquith, S., Sedelies, K. A., Bird, P. I., Waterhouse, N. J. & Trapani, J. A., 2013, In : Cell Death and Differentiation. 20, 9, p. 1183 - 1193 11 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)

Controversies in granzyme biology

Susanto, O., Trapani, J. A. & Brasacchio, D., Dec 2012, In : Tissue Antigens. 80, 6, p. 477-487 11 p.

Research output: Contribution to journalArticleResearchpeer-review