Projects per year
Personal profile
Biography
Daniel is a post-doctoral researcher in the Nanomaterials for Biology group led by A/Prof. Angus Johnston. His work focuses on developing delivery methods for new biological therapeutics.
Daniel’s research interests include:
– Protein-polymer conjugates and protein conjugation chemistry
– Protein engineering and recombinant protein expression
- Nucleic acid delivery systems
– Synthetic biology, bio-assembled nanoparticle-based drug delivery systems
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Molecular Biology
- Protein engineering
- Bioconjugation
- Nanomedicine
- Nanobiosensors
Projects
- 1 Finished
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Protein engineering approaches to next generation targeting agents
Porter, C. (Primary Chief Investigator (PCI)), Johnston, A. (Chief Investigator (CI)), Owen, D. J. (Partner Investigator (PI)) & Yuen, D. (Chief Investigator (CI))
1/04/17 → 31/03/20
Project: Research
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A Method for High-Throughput Screening of Monoclonal Antibody Internalization Using a DNA/Protein Molecular Staple
Mollé, L. M., Smyth, C. H., Herling, B. R., Yuen, D. & Johnston, A. P. R., 2025, (Accepted/In press) In: Small Methods. 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
A versatile antibody capture system drives specific in vivo delivery of mRNA-loaded lipid nanoparticles
Chen, M. Z., Yuen, D., McLeod, V. M., Yong, K. W., Smyth, C. H., Herling, B. R., Payne, T. J., Fabb, S. A., Belousoff, M. J., Algarni, A., Sexton, P. M., Porter, C. J. H., Pouton, C. W. & Johnston, A. P. R., 4 Aug 2025, In: Nature Nanotechnology. 20, p. 1273–1284 21 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Gene Delivery with Dual pH- and GSH-Responsive Lipoamide Polymers from Controlled Polymerization of Protected Lipoic Acid
Yang, F., Zhang, C., Smith, S. A., Rossi Herling, B., Yuen, D., Wang, Y., Nayanathara, U., Gao, Y., Johnston, A. P. R. & Such, G. K., 11 Jun 2025, In: ACS Applied Materials & Interfaces. 17, 23, p. 33756–33769 14 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Nanobody-Mediated Cellular Uptake Maximizes the Potency of Polylysine Dendrimers While Preserving Solid Tumor Penetration
Yuen, D., Feeney, O. M., Noi, L., Shengule, S., McLeod, V. M., Reitano, P., Tsegay, S., Hufton, R., Houston, Z. H., Fletcher, N. L., Humphries, J., Thurecht, K. J., Cullinane, C., Owen, D. J., Porter, C. J. H. & Johnston, A. P. R., 18 Feb 2025, In: ACS Nano. 19, 6, p. 6044–6057 14 p.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
Cholic-Acid Derived, Guanidine-Functionalized Polymers as Broad-Spectrum Antimicrobial Agents
Xiong, Y., Nayanathara, U., Lai, X., Huang, X., Zhang, C., Yuen, D., Sangwan, P., Shen, H. H., Johnston, A. P. R., Muir, B. W. & Such, G. K., 25 Nov 2024, In: ACS Omega. 9, 49, p. 48738–48747 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access