19982022
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Research Output 1998 2019

Article
52 Citations (Scopus)

Role of beta-Adrenoceptors in Memory Consolidation: beta3-Adrenoceptors Act on Glucose Uptake and beta2-Adrenoceptors on Glycogenolysis

Gibbs, M. E., Hutchinson, D. S. & Summers, R. J., 2008, In : Neuropsychopharmacology. 33, p. 2384 - 2397 13 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Rosiglitazone and a β3-adrenoceptor agonist are both required for functional browning of white adipocytes in culture

Merlin, J., Sato, M., Chia, L. Y., Fahey, R., Pakzad, M., Nowell, C. J., Summers, R. J., Bengtsson, T., Evans, B. A. & Hutchinson, D. S., 30 May 2018, In : Frontiers in Endocrinology. 9, MAY, 17 p., 249.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
20 Citations (Scopus)

Shikonin increases glucose uptake in skeletal muscle cells and improves plasma glucose levels in diabetic goto-kakizaki rats

Oberg, A., Yassin, K., Csikasz, R., Dehvari, N., Shabalina, I., Hutchinson, D., Wilcke, M., Goran-Ostenson, C. & Bengtsson, T., 2011, In : PLoS ONE. 6, 7, 10 p., e22510.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
13 Citations (Scopus)

Signal transduction pathways activated by insulin-like peptide 5 at the relaxin family peptide RXFP4 receptor

Ang, S. Y., Hutchinson, D. S., Patil, N., Evans, B. A., Bathgate, R. A. D., Halls, M. L., Hossain, M. A., Summers, R. J. & Kocan, M., 1 May 2017, In : British Journal of Pharmacology. 174, 10, p. 1077-1089 13 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Stereoselectivity for interactions of agonists and antagonists at mouse, rat and human 3-adrenoceptors

Popp, B. D., Hutchinson, D. S., Evans, B. A. & Summers, R. J., 2004, In : European Journal of Pharmacology. 484, 2-3, p. 323 - 331 9 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

The actions of relaxin family peptides on signal transduction pathways activated by the relaxin family peptide receptor RXFP4

Ang, S. Y., Hutchinson, D. S., Evans, B. A., Hossain, M. A., Patil, N., Bathgate, R. A. D., Kocan, M. & Summers, R. J., Jan 2017, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 390, 1, p. 105-111 7 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15

Delconte, R. B., Shi, W., Sathe, P., Ushiki, T., Seillet, C., Minnich, M., Kolesnik, T. B., Rankin, L. C., Mielke, L. A., Zhang, J-G., Busslinger, M., Smyth, M. J., Hutchinson, D. S., Nutt, S. L., Nicholson, S. E., Alexander, W. S., Corcoran, L. M., Vivier, E., Belz, G. T., Carotta, S. & 1 others, Huntington, N. D., 19 Jan 2016, In : Immunity. 44, 1, p. 103-115 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
10 Citations (Scopus)

The Janus faces of adrenoceptors: factors controlling the coupling of adrenoceptors to multiple signal transduction pathways

Summers, R. J., Broxton, N., Hutchinson, D. S. & Evans, B. A., 2004, In : Clinical and Experimental Pharmacology and Physiology. 31, 11, p. 822 - 827 6 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

The M3-muscarinic acetylcholine receptor stimulates glucose uptake in L6 skeletal muscle cells by a CaMKK-AMPK-dependent mechanism

Merlin, J., Evans, B. A., Csikasz, R. I., Bengtsson, T., Summers, R. J. & Hutchinson, D. S., 2010, In : Cellular Signalling. 22, 7, p. 1104 - 1113 10 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

The PPARγ agonist rosiglitazone promotes the induction of brite adipocytes, increasing β-adrenoceptor-mediated mitochondrial function and glucose uptake

Merlin, J., Sato, M., Nowell, C., Pakzad, M., Fahey, R., Gao, J., Dehvari, N., Summers, R. J., Bengtsson, T., Evans, B. A. & Hutchinson, D. S., 1 Jan 2018, In : Cellular Signalling. 42, p. 54-66 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity

Rautela, J., Dagley, L. F., De Oliveira, C. C., Schuster, I. S., Hediyeh-Zadeh, S., Delconte, R. B., Cursons, J., Hennessy, R., Hutchinson, D. S., Harrison, C., Kita, B., Vivier, E., Webb, A. I., Degli-Esposti, M. A., Davis, M. J., Huntington, N. D. & Souza-Fonseca-Guimaraes, F., 27 Aug 2019, In : Science Signaling. 12, 596, 13 p., aat7527.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

α1A-Adrenoceptors activate mTOR signalling and glucose uptake in cardiomyocytes

Sato, M., Evans, B. A., Sandström, A. L., Chia, L. Y., Mukaida, S., Thai, B. S., Nguyen, A., Lim, L., Tan, C. Y. R., Baltos, J. A., White, P. J., May, L. T., Hutchinson, D. S., Summers, R. J. & Bengtsson, T., 1 Feb 2018, In : Biochemical Pharmacology. 148, p. 27-40 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
35 Citations (Scopus)

β1-adrenergic receptors increase UCP1 in human MADS brown adipocytes and rescue cold-acclimated β3-adrenergic receptor knockout mice via nonshivering thermogenesis

Mattsson, C. L., Csikasz, R. I., Chernogubova, E., Yamamoto, D. L., Hogberg, H. T., Amri, E-Z., Hutchinson, D. S. & Bengtsson, T., Dec 2011, In : American Journal of Physiology - Endocrinology and Metabolism. 301, 6, 11 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

β1-adrenoceptors compensate for β3-adrenoceptors in ileum from β3-adrenoceptor knock-out mice

Hutchinson, D. S., Evans, B. A. & Summers, R. J., 1 Jan 2001, In : British Journal of Pharmacology. 132, 2, p. 433-442 10 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

β2-adrenergic activation increases glycogen synthesis in L6 skeletal muscle cells through a signalling pathway independent of cyclic AMP

Yamamoto, D. L., Hutchinson, D. S. & Bengtsson, T., 2007, In : Diabetologia. 50, 1, p. 158 - 167 10 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

β3-adrenoceptor regulation and relaxation responses in mouse ileum

Hutchinson, D. S., Evans, B. A. & Summers, R. J., 1 Jan 2000, In : British Journal of Pharmacology. 129, 6, p. 1251-1259 9 p.

Research output: Contribution to journalArticleResearchpeer-review

β3-Andrenoceptors: Differential regulation and novel subtypes

Summers, R. J., Hutchinson, D. S. & Evans, B. A., 1 Jan 1998, In : Pharmacology and Toxicology, Supplement. 83, 1, p. 37-39 3 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

βs-Adrenoceptors: Their role and regulation in the gastrointestinal tract

Summers, R. J., Roberts, S. J., Hutchinson, D. S. & Evans, B. A., 1 Dec 1999, In : Proceedings of the Western Pharmacology Society. 42, p. 115-117 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Comment / Debate

Quantification of functional selectivity at the human α1A- adrenoceptor (Molecular Pharmacology (2011) 79, (298-307))

Evans, B. A., Broxton, N., Merlin, J., Sato, M., Hutchinson, D. S., Christopoulos, A. & Summers, R. J., Mar 2011, In : Molecular Pharmacology. 79, 3, p. 627 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Conference Paper

B3 -adrenorecoptors: differential regulations and novel subtypes

Summers, R. J., Hutchinson, D. S. & Evans, B. A., 1998, Pharmacology and Toxicology. Copenhagan Denmark: Nordic Pharmacological Society, p. 37 - 39 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Review Article
1 Citation (Scopus)

Adrenoceptor regulation of the mechanistic target of rapamycin in muscle and adipose tissue

Chia, L. Y., Evans, B., Mukaida, S., Bengtsson, T., Hutchinson, D. & Sato, M., 1 Jul 2019, In : British Journal of Pharmacology. 176, 14, p. 2433-2448 16 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

Adrenoceptors in white, brown, and brite adipocytes

Evans, B. A., Merlin, J., Bengtsson, T. & Hutchinson, D. S., 1 Jul 2019, In : British Journal of Pharmacology. 176, 14, p. 2416-2432 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

8 Citations (Scopus)

G protein coupled receptor 18: a potential role for endocannabinoid signaling in metabolic dysfunction

Rajaraman, G., Simcocks, A., Hryciw, D. H., Hutchinson, D. S. & McAinch, A. J., 1 Jan 2016, In : Molecular Nutrition and Food Research. 60, 1, p. 92-102 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

10 Citations (Scopus)

Mirabegron: potential off target effects and uses beyond the bladder

Dehvari, N., Dantas da Silva Junior, E., Bengtsson, T. & Hutchinson, D. S., 1 Nov 2018, In : British Journal of Pharmacology. 175, 21, p. 4072-4082 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

6 Citations (Scopus)

Peripheral modulation of the endocannabinoid system in metabolic disease

Shrestha, N., Cuffe, J. S. M., Hutchinson, D. S., Headrick, J. P., Perkins, A. V., McAinch, A. J. & Hryciw, D. H., 1 Mar 2018, In : Drug Discovery Today. 23, 3, p. 592-604 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review