Dana Hutchinson

Research output

Research output per year 1998 1998 2005 2006 2007 2008 2011 2016 2017 2018 2019 2023

• 64 Article
• 8 Abstract
• 6 Review Article
• 2 Conference Paper
• 3 More
  • 2 Letter
  • 1 Comment / Debate

Research output per year

Research output per year

Search results

• 2023

  Targeting G protein-coupled receptors for heart failure treatment

  Thai, B. S., Chia, L. Y., Nguyen, A. T. N., Qin, C., Ritchie, R. H., Hutchinson, D. S., Kompa, A., White, P. J. & May, L. T., 24 Apr 2023, (Accepted/In press) In: British Journal of Pharmacology. 17 p.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access
• 2022

  Pharmacophore-guided Virtual Screening to Identify New β₃-adrenergic Receptor Agonists

  Ujiantari, N. S. O., Ham, S., Nagiri, C., Shihoya, W., Nureki, O., Hutchinson, D. S. & Schuster, D., Jul 2022, In: Molecular Informatics. 41, 7, 14 p., 2100223.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  8 Citations (Scopus)
• 2021

  GPR55 regulates the responsiveness to, but does not dimerise with, α_1A-adrenoceptors

  Walsh, S. K., Lipina, C., Ang, S. Y., Sato, M., Chia, L. Y., Kocan, M., Hutchinson, D. S., Summers, R. J. & Wainwright, C. L., Jun 2021, In: Biochemical Pharmacology. 188, 12 p., 114560.

  Research output: Contribution to journal › Article › Research › peer-review
• 2020

  The metabolic effects of mirabegron are mediated primarily by β₃-adrenoceptors

  Dehvari, N., Sato, M., Bokhari, M. H., Kalinovich, A., Ham, S., Gao, J., Nguyen, H. T. M., Whiting, L., Mukaida, S., Merlin, J., Chia, L. Y., Wootten, D., Summers, R. J., Evans, B. A., Bengtsson, T. & Hutchinson, D. S., 1 Oct 2020, In: Pharmacology Research & Perspectives. 8, 5, 16 p., e00643.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  9 Citations (Scopus)
• 2019

  Acute β-adrenoceptor mediated glucose clearance in brown adipose tissue; a distinct pathway independent of functional insulin signaling

  Olsen, J. M., Åslund, A., Bokhari, M. H., Hutchinson, D. S. & Bengtsson, T., Dec 2019, In: Molecular Metabolism. 30, p. 240-249 10 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  14 Citations (Scopus)

• Adrenoceptor regulation of the mechanistic target of rapamycin in muscle and adipose tissue

  Chia, L. Y., Evans, B., Mukaida, S., Bengtsson, T., Hutchinson, D. & Sato, M., 1 Jul 2019, In: British Journal of Pharmacology. 176, 14, p. 2433-2448 16 p.

  Research output: Contribution to journal › Review Article › Research › peer-review

  Open Access

  File
  8 Citations (Scopus)

• Adrenoceptors in white, brown, and brite adipocytes

  Evans, B. A., Merlin, J., Bengtsson, T. & Hutchinson, D. S., 1 Jul 2019, In: British Journal of Pharmacology. 176, 14, p. 2416-2432 17 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  36 Citations (Scopus)

• BRL37344 stimulates GLUT4 translocation and glucose uptake in skeletal muscle via β ₂ -adrenoceptors without causing classical receptor desensitization

  Mukaida, S., Sato, M., Öberg, A. I., Dehvari, N., Olsen, J. M., Kocan, M., Halls, M. L., Merlin, J., Sandström, A. L., Csikasz, R. I., Evans, B. A., Summers, R. J., Hutchinson, D. S. & Bengtsson, T., 1 May 2019, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 316, 5, p. R666-R677 12 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  12 Citations (Scopus)

• Expression and activity of the calcitonin receptor family in a sample of primary human high-grade gliomas

  Ostrovskaya, A., Hick, C., Hutchinson, D. S., Stringer, B. W., Wookey, P. J., Wootten, D., Sexton, P. M. & Furness, S. G. B., 18 Feb 2019, In: BMC Cancer. 19, 1, 12 p., 157.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  11 Citations (Scopus)

• Metabolic effects of mirabegron in primary adipocytes in vitro, and on metabolic parameters in vivo

  Hutchinson, D., Dehvari, N., Sato, M., Gao, W., Whiting, L., Kalinovich, A., Mukaida, S., Merlin, J., Wootten, D. L., Summers, R. J., Evans, B. & Bengtsson, T., May 2019, p. 283-283. 1 p.

  Research output: Contribution to conference › Abstract

  Open Access

• Therapeutic blockade of activin-A improves NK cell function and antitumor immunity

  Rautela, J., Dagley, L. F., De Oliveira, C. C., Schuster, I. S., Hediyeh-Zadeh, S., Delconte, R. B., Cursons, J., Hennessy, R., Hutchinson, D. S., Harrison, C., Kita, B., Vivier, E., Webb, A. I., Degli-Esposti, M. A., Davis, M. J., Huntington, N. D. & Souza-Fonseca-Guimaraes, F., 27 Aug 2019, In: Science Signaling. 12, 596, 13 p., aat7527.

  Research output: Contribution to journal › Article › Research › peer-review
  49 Citations (Scopus)
• 2018

  Effects of hypoxia-ischemia and inotropes on expression of cardiac adrenoceptors in the preterm fetal sheep

  Hutchinson, D. S., Brew, N., Vu, T., Merlin, J., Hale, N., Walker, D. W. & Wong, F. Y., 1 Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1368-1377 10 p.

  Research output: Contribution to journal › Article › Research › peer-review
  3 Citations (Scopus)

• INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells

  Ang, S. Y., Evans, B. A., Poole, D. P., Bron, R., DiCello, J. J., Bathgate, R. A. D., Kocan, M., Hutchinson, D. S. & Summers, R. J., 1 Apr 2018, In: Journal of Molecular Endocrinology. 60, 3, p. 213-224 12 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  13 Citations (Scopus)

• Mirabegron: potential off target effects and uses beyond the bladder

  Dehvari, N., Dantas da Silva Junior, E., Bengtsson, T. & Hutchinson, D. S., 1 Nov 2018, In: British Journal of Pharmacology. 175, 21, p. 4072-4082 11 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  41 Citations (Scopus)

• Peripheral modulation of the endocannabinoid system in metabolic disease

  Shrestha, N., Cuffe, J. S. M., Hutchinson, D. S., Headrick, J. P., Perkins, A. V., McAinch, A. J. & Hryciw, D. H., 1 Mar 2018, In: Drug Discovery Today. 23, 3, p. 592-604 13 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  30 Citations (Scopus)

• Rosiglitazone and a β₃-adrenoceptor agonist are both required for functional browning of white adipocytes in culture

  Merlin, J., Sato, M., Chia, L. Y., Fahey, R., Pakzad, M., Nowell, C. J., Summers, R. J., Bengtsson, T., Evans, B. A. & Hutchinson, D. S., 30 May 2018, In: Frontiers in Endocrinology. 9, MAY, 17 p., 249.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  25 Citations (Scopus)

• The PPARγ agonist rosiglitazone promotes the induction of brite adipocytes, increasing β-adrenoceptor-mediated mitochondrial function and glucose uptake

  Merlin, J., Sato, M., Nowell, C., Pakzad, M., Fahey, R., Gao, J., Dehvari, N., Summers, R. J., Bengtsson, T., Evans, B. A. & Hutchinson, D. S., 1 Jan 2018, In: Cellular Signalling. 42, p. 54-66 13 p.

  Research output: Contribution to journal › Article › Research › peer-review
  36 Citations (Scopus)

• α_1A-Adrenoceptors activate mTOR signalling and glucose uptake in cardiomyocytes

  Sato, M., Evans, B. A., Sandström, A. L., Chia, L. Y., Mukaida, S., Thai, B. S., Nguyen, A., Lim, L., Tan, C. Y. R., Baltos, J. A., White, P. J., May, L. T., Hutchinson, D. S., Summers, R. J. & Bengtsson, T., 1 Feb 2018, In: Biochemical Pharmacology. 148, p. 27-40 14 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  17 Citations (Scopus)
• 2017

  Adrenoceptors promote glucose uptake into adipocytes and muscle by an insulin-independent signaling pathway involving mechanistic target of rapamycin complex 2

  Mukaida, S., Evans, B. A., Bengtsson, T., Hutchinson, D. S. & Sato, M., 1 Feb 2017, In: Pharmacological Research. 116, p. 87-92 6 p.

  Research output: Contribution to journal › Article › Research › peer-review
  24 Citations (Scopus)

• Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus

  Jiao, Y., Preston, S., Song, H., Jabbar, A., Liu, Y., Baell, J., Hofmann, A., Hutchinson, D., Wang, T., Koehler, A. V., Fisher, G. M., Andrews, K. T., Laleu, B., Palmer, M. J., Burrows, J. N., Wells, T. N. C., Wang, Q. & Gasser, R. B., 31 May 2017, In: Parasites & Vectors. 10, 1, 272.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  23 Citations (Scopus)

• Factors influencing biased agonism in recombinant cells expressing the human α_1A-adrenoceptor

  da Silva Junior, E. D., Sato, M., Merlin, J., Broxton, N., Hutchinson, D. S., Ventura, S., Evans, B. A. & Summers, R. J., 1 Jul 2017, In: British Journal of Pharmacology. 174, 14, p. 2318-2333 16 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  23 Citations (Scopus)

• ML290 is a biased allosteric agonist at the relaxin receptor RXFP1

  Kocan, M., Sarwar, M., Ang, S. Y., Xiao, J., Marugan, J., Hossain, M. A., Wang, C., Hutchinson, D. S., Samuel, C. S., Agoulnik, A. I., Bathgate, R. A. D. & Summers, R. J., 1 Dec 2017, In: Scientific Reports. 7, 1, 14 p., 2968.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  42 Citations (Scopus)

• Signal transduction pathways activated by insulin-like peptide 5 at the relaxin family peptide RXFP4 receptor

  Ang, S. Y., Hutchinson, D. S., Patil, N., Evans, B. A., Bathgate, R. A. D., Halls, M. L., Hossain, M. A., Summers, R. J. & Kocan, M., 1 May 2017, In: British Journal of Pharmacology. 174, 10, p. 1077-1089 13 p.

  Research output: Contribution to journal › Article › Research › peer-review
  26 Citations (Scopus)

• The actions of relaxin family peptides on signal transduction pathways activated by the relaxin family peptide receptor RXFP4

  Ang, S. Y., Hutchinson, D. S., Evans, B. A., Hossain, M. A., Patil, N., Bathgate, R. A. D., Kocan, M. & Summers, R. J., Jan 2017, In: Naunyn-Schmiedeberg's Archives of Pharmacology. 390, 1, p. 105-111 7 p.

  Research output: Contribution to journal › Article › Research › peer-review
  9 Citations (Scopus)
• 2016

  CIS is a potent checkpoint in NK cell-mediated tumor immunity

  Delconte, R. B., Kolesnik, T. B., Dagley, L. F., Rautela, J., Shi, W., Putz, E. M., Stannard, K., Zhang, J. G., Teh, C. E-Y., Firth, M., Ushiki, T., Andoniou, C. E., Degli-Esposti, M. A., Sharp, P. P., Sanvitale, C. E., Infusini, G., Liau, N. P. D., Linossi, E. M., Burns, C. J., Carotta, S., & 12 othersGray, D. H. D., Seillet, C., Hutchinson, D. S., Belz, G. T., Webb, A. I., Alexander, W. S., Li, S. S., Bullock, A. N., Babon, J. J., Smyth, M. J., Nicholson, S. E. & Huntington, N. D., 21 Jun 2016, In: Nature Immunology. 17, 7, p. 816-824 9 p.

  Research output: Contribution to journal › Article › Research › peer-review
  238 Citations (Scopus)

• Could burning fat start with a brite spark? Pharmacological and nutritional ways to promote thermogenesis

  Merlin, J., Evans, B. A., Dehvari, N., Sato, M., Bengtsson, T. & Hutchinson, D. S., 2016, In: Molecular Nutrition & Food Research. 60, 1, p. 18-42 25 p.

  Research output: Contribution to journal › Article › Research › peer-review
  39 Citations (Scopus)

• G protein coupled receptor 18: a potential role for endocannabinoid signaling in metabolic dysfunction

  Rajaraman, G., Simcocks, A., Hryciw, D. H., Hutchinson, D. S. & McAinch, A. J., 1 Jan 2016, In: Molecular Nutrition & Food Research. 60, 1, p. 92-102 11 p.

  Research output: Contribution to journal › Review Article › Research › peer-review
  31 Citations (Scopus)

• The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15

  Delconte, R. B., Shi, W., Sathe, P., Ushiki, T., Seillet, C., Minnich, M., Kolesnik, T. B., Rankin, L. C., Mielke, L. A., Zhang, J-G., Busslinger, M., Smyth, M. J., Hutchinson, D. S., Nutt, S. L., Nicholson, S. E., Alexander, W. S., Corcoran, L. M., Vivier, E., Belz, G. T., Carotta, S., & 1 othersHuntington, N. D., 19 Jan 2016, In: Immunity. 44, 1, p. 103-115 13 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  88 Citations (Scopus)
• 2015

  DNAM-1 expression marks an alternative program of NK cell maturation

  Martinet, L., de Andrade, L. F., Guillerey, C., Lee, J. S., Liu, J., Souza-Fonseca-Guimaraes, F., Hutchinson, D. S., Kolesnik, T. B., Nicholson, S. E., Huntington, N. D. & Smyth, M. J., 2015, In: Cell Reports. 11, 1, p. 85 - 97 13 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  87 Citations (Scopus)
• 2014

  Glucose uptake in brown fat cells is dependent on mTOR complex 2-promoted GLUT1 translocation

  Olsen, J. M., Sato, M., Dallner, O. S., Sandstrom, A. L., Pisani, D. F., Chambard, J-C., Amri, E-Z., Hutchinson, D. S. & Bengtsson, T., 2014, In: Journal of Cell Biology. 207, 3, p. 365 - 374 10 p.

  Research output: Contribution to journal › Article › Research › peer-review
  120 Citations (Scopus)

• Improving type 2 diabetes through a distinct adrenergic signaling pathway involving mTORC2 that mediates glucose uptake in skeletal muscle

  Sato, M., Dehvari, N., Oberg, A., Dallner, O. S., Sandstrom, A. L., Olsen, J. M., Csikasz, R. I., Summers, R. J., Hutchinson, D. S. & Bengtsson, T., 2014, In: Diabetes. 63, 12, p. 4115 - 4129 15 p.

  Research output: Contribution to journal › Article › Research › peer-review
  88 Citations (Scopus)

• Response to Comment on Sato et al. Improving type 2 diabetes through a distinct adrenergic signaling pathway involving mTORC2 that mediates glucose uptake in skeletal muscle. Diabetes 2014;63:4115-4129

  Sato, M., Dehvari, N., Oberg, A., Summers, R. J., Hutchinson, D. S. & Bengtsson, T., 2014, In: Diabetes. 63, 12, p. 22 - 23 2 p.

  Research output: Contribution to journal › Letter › Other
  4 Citations (Scopus)
• 2013

  {beta}Adrenoceptor-mediated regulation of glucose uptake in skeletal muscle-ligand-directed signalling or a reflection of system complexity?

  Evans, B. A., Hutchinson, D. S. & Summers, R. J., 2013, In: Naunyn-Schmiedeberg's Archives of Pharmacology. 386, 9, p. 757 - 760 4 p.

  Research output: Contribution to journal › Letter › Other
  5 Citations (Scopus)

• Orthosteric binding of rho-Da1a, a natural peptide of snake venom interacting selectively with the alpha(1A)-Adrenoceptor

  Maiga, A., Merlin, J., Marcon, E., Rouget, C., Larregola, M., Gilquin, B., Fruchart-Gaillard, C., Lajeunesse, E., Marchetti, C., Lorphelin, A., Bellanger, L., Summers, R. J., Hutchinson, D. S., Evans, B. A., Servent, D. & Gilles, N., 2013, In: PLoS ONE. 8, 7, 11 p., e68841.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  8 Citations (Scopus)
• 2012

  Beta(2)-adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C-terminal tail

  Dehvari, N., Hutchinson, D., Nevzorova, J., Dallner, O., Sato, M., Kocan, M., Merlin, J., Evans, B., Summers, R. & Bengtsson, T., 2012, In: British Journal of Pharmacology. 165, 5, p. 1442 - 1456 15 p.

  Research output: Contribution to journal › Article › Research › peer-review
  23 Citations (Scopus)

• Interaction with caveolin-1 modulates G protein coupling of the mouse beta3-adrenoceptor

  Sato, M., Hutchinson, D. S., Halls, M. L., Furness, S. G. B., Bengtsson, T., Evans, B. A. & Summers, R. J., 2012, In: Journal of Biological Chemistry. 287, 24, p. 20674 - 20688 15 p.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access

  File
  23 Citations (Scopus)

• Rapid turnover of glycogen in memory formation

  Gibbs, M. E. & Hutchinson, D. S., 2012, In: Neurochemical Research. 37, 11, p. 2456 - 2463 8 p.

  Research output: Contribution to journal › Article › Research › peer-review
  26 Citations (Scopus)
• 2011

  alpha{2}-Adrenoceptors activate noradrenaline-mediated glycogen turnover in chick astrocytes

  Hutchinson, D. S., Catus, S. L., Merlin, J., Summers, R. J. & Gibbs, M. E., 2011, In: Journal of Neurochemistry. 117, 5, p. 915 - 926 12 p.

  Research output: Contribution to journal › Article › Research › peer-review
  24 Citations (Scopus)

• Quantification of functional selectivity at the human {alpha}1A-adrenoceptor

  Evans, B. A., Broxton, N., Merlin, J., Sato, M., Hutchinson, D. S., Christopoulos, A. & Summers, R. J., 2011, In: Molecular Pharmacology. 79, 2, p. 298 - 307 10 p.

  Research output: Contribution to journal › Article › Research › peer-review
  62 Citations (Scopus)

• Quantification of functional selectivity at the human α1A- adrenoceptor (Molecular Pharmacology (2011) 79, (298-307))

  Evans, B. A., Broxton, N., Merlin, J., Sato, M., Hutchinson, D. S., Christopoulos, A. & Summers, R. J., Mar 2011, In: Molecular Pharmacology. 79, 3, p. 627 1 p.

  Research output: Contribution to journal › Comment / Debate › Other › peer-review

• Role of beta-adrenoceptors in glucose uptake in astrocytes using beta-adrenoceptor knockout mice

  Catus, S. L., Gibbs, M. E., Sato, M., Summers, R. J. & Hutchinson, D. S., 2011, In: British Journal of Pharmacology. 162, 8, p. 1700 - 1715 16 p.

  Research output: Contribution to journal › Article › Research › peer-review
  45 Citations (Scopus)

• Shikonin increases glucose uptake in skeletal muscle cells and improves plasma glucose levels in diabetic goto-kakizaki rats

  Oberg, A., Yassin, K., Csikasz, R., Dehvari, N., Shabalina, I., Hutchinson, D., Wilcke, M., Goran-Ostenson, C. & Bengtsson, T., 2011, In: PLoS ONE. 6, 7, 10 p., e22510.

  Research output: Contribution to journal › Article › Research › peer-review

  Open Access
  35 Citations (Scopus)

• β₁-adrenergic receptors increase UCP1 in human MADS brown adipocytes and rescue cold-acclimated β₃-adrenergic receptor knockout mice via nonshivering thermogenesis

  Mattsson, C. L., Csikasz, R. I., Chernogubova, E., Yamamoto, D. L., Hogberg, H. T., Amri, E-Z., Hutchinson, D. S. & Bengtsson, T., Dec 2011, In: American Journal of Physiology - Endocrinology and Metabolism. 301, 6, 11 p.

  Research output: Contribution to journal › Article › Research › peer-review
  50 Citations (Scopus)
• 2010

  Ligand-directed signalling at beta-adrenoceptors

  Evans, B., Sato, M., Sarwar, M., Hutchinson, D. & Summers, R., 2010, In: British Journal of Pharmacology. 159, 5, p. 1022 - 1038 17 p.

  Research output: Contribution to journal › Article › Research › peer-review
  134 Citations (Scopus)

• Noradrenaline release in the locus coeruleus modulates memory formation and consolidation; roles for alpha- and beta-adrenergic receptors

  Gibbs, M. E., Hutchinson, D. S. & Summers, R. J., 2010, In: Neuroscience. 170, 4, p. 1209 - 1222 14 p.

  Research output: Contribution to journal › Article › Research › peer-review
  66 Citations (Scopus)

• The M3-muscarinic acetylcholine receptor stimulates glucose uptake in L6 skeletal muscle cells by a CaMKK-AMPK-dependent mechanism

  Merlin, J., Evans, B. A., Csikasz, R. I., Bengtsson, T., Summers, R. J. & Hutchinson, D. S., 2010, In: Cellular Signalling. 22, 7, p. 1104 - 1113 10 p.

  Research output: Contribution to journal › Article › Research › peer-review
  37 Citations (Scopus)
• 2009

  Importance of adrenergic receptors in prenatally induced cognitive impairment in the domestic chick

  Gibbs, M. E., Rodricks, C. L., Hutchinson, D. S., Summers, R. J. & Miller, S. L., 2009, In: International Journal of Developmental Neuroscience. 27, p. 27 - 35 8 p.

  Research output: Contribution to journal › Article › Research › peer-review

  4 Citations (Scopus)
• 2008

  Astrocytic involvement in learning and memory consolidation

  Gibbs, M. E., Hutchinson, D. S. & Hertz, L., 2008, In: Neuroscience and Biobehavioral Reviews. 32, 5, p. 927 - 944 18 p.

  Research output: Contribution to journal › Article › Research › peer-review

  131 Citations (Scopus)

• Energy metabolism and memory processing: Role of glucose transport and glycogen in responses to adrenoceptor activation in the chicken

  Hutchinson, D. S., Summers, R. J. & Gibbs, M. E., 2008, In: Brain Research Bulletin. 76, 3, p. 224 - 234 11 p.

  Research output: Contribution to journal › Article › Research › peer-review

  28 Citations (Scopus)

• Memory processing in the avian hippocampus involves interactions between beta-adrenoceptors, glutamate receptors, and metabolism

  Gibbs, M. E., Bowser, D. N., Hutchinson, D. S., Loiacono, R. & Summers, R. J., 2008, In: Neuropsychopharmacology. 33, 12, p. 2831 - 2846 16 p.

  Research output: Contribution to journal › Article › Research › peer-review

  29 Citations (Scopus)