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Personal profile


Dakang Xu works in the Centre for Cancer Research at the Hudson Institute of Medical Research. The main focus of his research team is to characterise modulation of key regulators that affect inflammatory responses and tumour progression, through the function of immune cell subsets and cytokines in cancer and inflammatory diseases. This work has led to 40 peer-reviewed publications in high impact journals, including Nat Immunol, Immunity, Nat Commun, PNAS, EMBO J and Cancer Res. These include 15 papers as senior and corresponding author.

Research area keywords

  • Immunity
  • Cancer
  • Inflammation

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Projects 2010 2021

Research Output 2002 2018

5 Citations (Scopus)

(−)-Epigallocatechin-3-gallate and EZH2 inhibitor GSK343 have similar inhibitory effects and mechanisms of action on colorectal cancer cells

Ying, L., Yan, F., Williams, B. R. G., Xu, P., Li, X., Zhao, Y., Hu, Y., Wang, Y., Xu, D. & Dai, J., 1 Jan 2018, In : Clinical and Experimental Pharmacology and Physiology. 45, 1, p. 58-67 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Large-scale comparative assessment of computational predictors for lysine post-translational modification sites

Chen, Z., Liu, X., Li, F., Li, C., Marquez-Lago, T., Leier, A., Akutsu, T., Webb, G. I., Xu, D., Smith, A. I., Li, L., Chou, K-C. & Song, J., 4 Oct 2018, (Accepted/In press) In : Briefings in Bioinformatics. 24 p., bby089.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
7 Citations (Scopus)

PD-L1 expression is a prognostic factor in subgroups of gastric cancer patients stratified according to their levels of CD8 and FOXP3 immune markers

Ying, L., Yan, F., Meng, Q., Yu, L., Yuan, X., Gantier, M. P., Williams, B. R. G., Chan, D. W., Shi, L., Tu, Y., Ni, P., Wang, X., Chen, W., Zang, X., Xu, D. & Hu, Y., 20 Feb 2018, In : OncoImmunology. 7, 6, 11 p., e1433520.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

A non-canonical function of Ezh2 preserves immune homeostasis

Vasanthakumar, A., Xu, D., Lun, A. T. L., Kueh, A. J., van Gisbergen, K. P. J. M., Iannarella, N., Li, X., Yu, L., Wang, D., Williams, B. RG., Lee, S. C. W., Majewski, I. J., Godfrey, D. I., Smyth, G. K., Alexander, W. S., Herold, M. J., Kallies, A., Nutt, S. L. & Allan, R. S., 1 Apr 2017, In : EMBO Reports. 18, 4, p. 619-631 13 p.

Research output: Contribution to journalArticleResearchpeer-review

DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling

Chan, DW., Hui, W. W. Y., Wang, J. J., Yung, M. M. H., Hui, LMN., Qin, Y., Liang, RR., Leung, T. H. Y., Xu, D., Chan, KKL., Yao, K-M., Tsang, B. K. & Ngan, H. Y. S., 1 Mar 2017, In : Oncogene. 36, 10, p. 1404-1416 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access