20142020

Research output per year

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Personal profile

Biography

Dr. Yaping Chen received her PhD in Immunology from the Department of Biochemistry and Molecular Biology and the School of Biomedical Sciences, Monash University, in 2017. Her PhD research has focused on the discovery of the molecular mechanisms regulating the differentiation and function of the specialized population of follicular T lymphocytes.

From June, 2017, Dr. Yaping Chen joined Prof. Nicolas Voelcker’s group in Monash Institute of Pharmaceutical Sciences at Monash University, working on developing novel, smart and functional nano-bio interfaces between nanoscale materials and mammalian cells. Her research interest, particularly in but not limited to T cell modification using nanotechnology, provides major opportunities for collaboration and commercialization in Bio-Nano technology, CAR-T cell immunotherapy, stem cell reprogramming and related disciplines. 

Research interests


- Functional Bio-Nano interface

- Intracellular delivery and gene modification through nanoscale materials

- CAR-T cell immunotherapy in cancers and other diseases

- Stem cell reprogramming, CRISPR 

Research area keywords

  • Cell reprogramming
  • Intracellular delivery
  • CAR-T immunotherapy
  • Bio-Nano interface

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Research Output

A comparative study of cell growth on a cold sprayed Ti–Ta composite

Zeng, G., Zahiri, S. H., Gulizia, S., Chen, Y., Xu, C., Chen, X. B. & Cole, I., 15 Jun 2020, In : Journal of Alloys and Compounds. 826, 10 p., 154014.

Research output: Contribution to journalArticleResearchpeer-review

Silicon-Nanotube-Mediated Intracellular Delivery Enables Ex Vivo Gene Editing

Chen, Y., Aslanoglou, S., Murayama, T., Gervinskas, G., Fitzgerald, L. I., Sriram, S., Tian, J., Johnston, A. P. R., Morikawa, Y., Suu, K., Elnathan, R. & Voelcker, N. H., 18 Jun 2020, In : Advanced Materials. 32, 24, 10 p., 200036.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Cellular Deformations Induced by Conical Silicon Nanowire Arrays Facilitate Gene Delivery

Chen, Y., Aslanoglou, S., Gervinskas, G., Abdelmaksoud, H., Voelcker, N. H. & Elnathan, R., Nov 2019, In : Small. 15, 47, 14 p., 1904819.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

Combined Blockade of Smad3 and JNK Pathways Ameliorates Progressive Fibrosis in Folic Acid Nephropathy

Jiang, M., Fan, J., Qu, X., Li, S., Nilsson, S. K., Sun, Y. B. Y., Chen, Y., Yu, D., Liu, D., Liu, B-C., Tang, M., Chen, W., Ren, Y., Nikolic-Paterson, D. J., Jiang, X., Li, J. & Yu, X., 9 Aug 2019, In : Frontiers in Pharmacology. 10, 17 p., 880.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles

Leong, Y. A., Chen, Y., Ong, H. S., Wu, D., Man, K., Deleage, C., Minnich, M., Meckiff, B. J., Wei, Y., Hou, Z., Zotos, D., Fenix, K. A., Atnerkar, A., Preston, S., Chipman, J. G., Beilman, G. J., Allison, C. C., Sun, L., Wang, P., Xu, J. & 10 others, Toe, J. G., Lu, H. K., Tao, Y., Palendira, U., Dent, A. L., Landay, A. L., Pellegrini, M., Comerford, I., Lewin, S. R. & Yu, D., 3 Aug 2016, In : Nature Immunology. 17, 10, p. 1187-1196 10 p.

Research output: Contribution to journalArticleResearchpeer-review

146 Citations (Scopus)