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Personal profile


Dr. Yaping Chen received her PhD in Immunology from the Department of Biochemistry and Molecular Biology and the School of Biomedical Sciences, Monash University, in 2017. Her PhD research has focused on the discovery of the molecular mechanisms regulating the differentiation and function of the specialized population of follicular T lymphocytes.

From June, 2017, Dr. Yaping Chen joined Prof. Nicolas Voelcker’s group in Monash Institute of Pharmaceutical Sciences at Monash University, working on developing novel, smart and functional nano-bio interfaces between nanoscale materials and mammalian cells. Her research interest, particularly in but not limited to T cell modification using nanotechnology, provides major opportunities for collaboration and commercialization in Bio-Nano technology, CAR-T cell immunotherapy, stem cell reprogramming and related disciplines. 

Research interests

- Functional Bio-Nano interface

- Intracellular delivery and gene modification through nanoscale materials

- CAR-T cell immunotherapy in cancers and other diseases

- Stem cell reprogramming, CRISPR 

Research area keywords

  • Cell reprogramming
  • Intracellular delivery
  • CAR-T immunotherapy
  • Bio-Nano interface

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Research Output 2014 2019

  • 4 Article
  • 1 Comment / Debate
  • 1 Short Survey

Cellular Deformations Induced by Conical Silicon Nanowire Arrays Facilitate Gene Delivery

Chen, Y., Aslanoglou, S., Gervinskas, G., Abdelmaksoud, H., Voelcker, N. H. & Elnathan, R., 10 Oct 2019, (Accepted/In press) In : Small. 1904819.

Research output: Contribution to journalArticleResearchpeer-review

Combined Blockade of Smad3 and JNK Pathways Ameliorates Progressive Fibrosis in Folic Acid Nephropathy

Jiang, M., Fan, J., Qu, X., Li, S., Nilsson, S. K., Sun, Y. B. Y., Chen, Y., Yu, D., Liu, D., Liu, B-C., Tang, M., Chen, W., Ren, Y., Nikolic-Paterson, D. J., Jiang, X., Li, J. & Yu, X., 9 Aug 2019, In : Frontiers in Pharmacology. 10, 17 p., 880.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
126 Citations (Scopus)

CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles

Leong, Y. A., Chen, Y., Ong, H. S., Wu, D., Man, K., Deleage, C., Minnich, M., Meckiff, B. J., Wei, Y., Hou, Z., Zotos, D., Fenix, K. A., Atnerkar, A., Preston, S., Chipman, J. G., Beilman, G. J., Allison, C. C., Sun, L., Wang, P., Xu, J. & 10 others, Toe, J. G., Lu, H. K., Tao, Y., Palendira, U., Dent, A. L., Landay, A. L., Pellegrini, M., Comerford, I., Lewin, S. R. & Yu, D., 3 Aug 2016, In : Nature Immunology. 17, 10, p. 1187-1196 10 p.

Research output: Contribution to journalArticleResearchpeer-review

147 Citations (Scopus)

Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus

He, J., Zhang, X., Wei, Y., Sun, X., Chen, Y., Deng, J., Jin, Y., Gan, Y., Hu, X., Jia, R., Xu, C., Hou, Z., Leong, Y. A., Zhu, L., Feng, J., An, Y., Jia, Y., Li, C., Liu, X., Ye, H. & 12 others, Ren, L., Li, R., Yao, H., Li, Y., Chen, S., Zhang, X., Su, Y., Guo, J., Shen, N., Morand, E. F., Yu, D. & Li, Z., Sep 2016, In : Nature Medicine. 22, 9, p. 991-993 3 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

TCF-1 at the Tfh and Th1 Divergence

Chen, C. Y. & Yu, D., 2015, In : Trends in Immunology. 36, 12, p. 758-760 3 p.

Research output: Contribution to journalShort SurveyOtherpeer-review