1991 …2020

Research output per year

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Research Output

  • 20 Article
  • 5 Review Article
  • 2 Chapter (Book)
  • 1 Comment / Debate
2020

Frontline Science: Dynamic cellular and subcellular features of migrating leukocytes revealed by in vivo lattice lightsheet microscopy

Manley, H. R., Potter, D. L., Heddleston, J. M., Chew, T-L., Keightley, M. C. & Lieschke, G. J., 23 Apr 2020, (Accepted/In press) In : Journal of leukocyte biology. 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Splicing dysfunction and disease: The case of granulopoiesis

Keightley, M-C. & Lieschke, G. J., Mar 2018, In : Seminars in Cell and Developmental Biology. 75, p. 23-39 17 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

1 Citation (Scopus)

The Neutrophil Nucleus: An Important Influence on Neutrophil Migration and Function

Manley, H. R., Keightley, M. C. & Lieschke, G. J., 4 Dec 2018, In : Frontiers in Immunology. 9, 18 p., 2867.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
2017

A GCSFR/CSF3R zebrafish mutant models the persistent basal neutrophil deficiency of severe congenital neutropenia

Pazhakh, V., Clark, S., Keightley, M. C. & Lieschke, G. J., 10 Mar 2017, In : Scientific Reports. 7, 11 p., 44455.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
10 Citations (Scopus)

Intron retention enhances gene regulatory complexity in vertebrates

Schmitz, U., Pinello, N., Jia, F., Alasmari, S., Ritchie, W., Keightley, M-C., Shini, S., Lieschke, G. J., Wong, J. J. L. & Rasko, J. E. J., 16 Nov 2017, In : Genome Biology. 18, 1, 15 p., 216.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger

Keightley, M-C., Carradice, D. P., Layton, J. E., Pase, L., Bertrand, J. Y., Wittig, J. G., Dakic, A., Badrock, A. P., Cole, N. J., Traver, D., Nutt, S. L., McCoey, J., Buckle, A. M., Heath, J. K. & Lieschke, G. J., 6 Apr 2017, In : Nature Communications. 8, 13 p., 14911.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)
2016

Experimental approaches to studying the nature and impact of splicing variation in zebrafish

Keightley, M. C., Markmiller, S., Love, C. G., Rasko, J. E. . J., Lieschke, G. J. & Heath, J. K., 2016, Methods in Cell Biology: The Zebrafish: Genetics, Genomics, and Transcriptomics. Detrich, H. W., Westerfield, M. & Zon, L. I. (eds.). 4th ed. USA: Elsevier, Vol. 135. p. 259-288 29 p. (Methods in Cell Biology; vol. 135).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

2 Citations (Scopus)
2014

Delineating the roles of neutrophils and macrophages in zebrafish regeneration models

Keightley, M-C., Wang, C-H., Pazhakh, V. & Lieschke, G., 2014, In : International Journal of Biochemistry and Cell Biology. 56, p. 92 - 106 15 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Minor class splicing shapes the zebrafish transcriptome during development

Markmiller, S. J., Cloonan, N., Lardelli, R. M., Doggett, K., Keightley, M-C., Boglev, Y., Trotter, A., Ng, A. Y., Wilkins, S. J., Verkade, H., Ober, E. A., Field, H. A., Grimmond, S. M., Lieschke, G., Stainier, D. Y. R. & Heath, J. K., 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 8, p. 3062 - 3067 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
30 Citations (Scopus)
2013

Immune priming: mothering males modulate immunity

Keightley, M-C., Wong, B. B. M. & Lieschke, G., 2013, In : Current Biology. 23, 2, p. 76 - 78 3 p.

Research output: Contribution to journalComment / DebateResearchpeer-review

Open Access
4 Citations (Scopus)

In vivo mutation of pre-mRNA processing factor 8 (Prpf8) affects transcript splicing, cell survival and myeloid differentiation

Keightley, M-C., Crowhurst, M., Layton, J. E., Beilharz, T. H., Markmiller, S. J., Varma, S., Hogan, B. M., de Jong-Curtain, T. A., Heath, J. K. & Lieschke, G., 2013, In : FEBS Letters. 587, 14, p. 2150 - 2157 8 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)
2012

Neutrophil-delivered myeloperoxidase dampens the hydrogen peroxide burst after tissue wounding in zebrafish

Pase, L., Layton, J. E., Wittmann, C., Ellett, F., Nowell, C. J., Reyes-Aldasoro, C. C., Varma, S., Rogers, K. L., Hall, C. J., Keightley, M-C., Crosier, P. S., Grabher, C., Heath, J. K., Renshaw, S. A. & Lieschke, G. J., 2012, In : Current Biology. 22, 19, p. 1818 - 1824 7 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)
2011

Mediator subunit 12 is required for neutrophil development in zebrafish

Keightley, M-C., Layton, J., Hayman, J., Heath, J. & Lieschke, G., 2011, In : PLoS ONE. 6, 8, 8 p., e23845.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
14 Citations (Scopus)
2008

Relationship of cytomegalovirus load assessed by real-time PCR to pp65 antigenemia in organ transplant recipients

Sanghavi, S., Abu-Elmagd, K., Keightley, M-C., St George, K., Lewandowski, K., Boes, S. S., Bullotta, A., Dare, R., Lassak, M., Husain, S., Kwak, E. J., Paterson, D. L. & Rinaldo, C., 2008, In : Journal of Clinical Virology. 42, 4, p. 335 - 342 8 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)
2007

Diagnosis of human metapneumovirus infection in immimosuppressed lung transplant recipients and children evaluated for pertussis

Dare, R., Sanghavi, S., Bullotta, A., Keightley, M-C., St George, K., Wadowsky, R. M., Paterson, D. L., McCurry, K. R., Reinhart, T. A., Husain, S. & Rinaldo, C., 2007, In : Journal of Clinical Microbiology. 45, 2, p. 548 - 552 5 p.

Research output: Contribution to journalArticleResearchpeer-review

59 Citations (Scopus)
2006

Clinical utility of CMV early and late transcript detection with NASBA in bronchoalveolar lavages

Keightley, M-C., Rinaldo, C., Bullotta, A., Dauber, J. & St George, K., 2006, In : Journal of Clinical Virology. 37, 4, p. 258 - 264 7 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)
2005

Real-time NASBA detection of SARS-associated coronavirus and comparison with real-time reverse transcription-PCR

Keightley, M-C., Sillekens, P., Schippers, W., Rinaldo, C. & St George, K., 2005, In : Journal of Medical Virology. 77, 4, p. 602 - 608 7 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)
1998

Activation of Progesterone and Androgen Receptors by Signal Transduction Pathways.

Keightley, M-C., 1998, Molecular Basis of Sex Hormone Receptor Function: New Targets for Intervention . p. 89-108

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Steroid receptor isoforms: exception or rule?

Keightley, M-C., 1998, In : Molecular and Cellular Endocrinology.

Research output: Contribution to journalReview ArticleResearchpeer-review

Structural determinants of cortisol resistance in the guinea pig glucocorticoid receptor

Keightley, M. C., Curtis, A. J., Chu, S. & Fuller, P. J., 1998, In : Endocrinology. 139, 5, p. 2479-2485 7 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)
1997

Determinants of Specificity of Transactivation by the Mineralocorticoid or Glucocorticoid Receptor

Lim-Tio, S. S., Keightley, M-C. & Fuller, P. J., 1997, In : Endocrinology. p. 2537 - 2543 7 p.

Research output: Contribution to journalArticleResearchpeer-review

66 Citations (Scopus)
1996

Anomalies in the endocrine axes of the guinea pig: Relevance to human physiology and disease

Keightley, C. & Fuller, P. J., 1996, In : Endocrine Reviews. 17, 1, p. 30-44 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

45 Citations (Scopus)

The molecular basis of RU486 resistance in the tammar wallaby, Macropus eugenii

Lim-Tio, S. S., Keightley, M. C., Fletcher, T. P. & Fuller, P. J., 31 May 1996, In : Molecular and Cellular Endocrinology. 119, 2, p. 169-174 6 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)
1995

Cortisol resistance and the guinea pig glucocorticoid receptor

Keightley, M. C. & Fuller, P. J., 1995, In : Steroids. 60, 1, p. 87-92 6 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Human mineralocorticoid receptor genomic structure and identification of expressed isoforms

Zennaro, M-C., Keightley, M-C., Kotelevtsev, Y., Conway, G. S., Soubrier, F. & Fuller, P. J., 1995, In : Journal of Biological Chemistry. 270, 36, p. 21016-21020 5 p.

Research output: Contribution to journalArticleResearchpeer-review

100 Citations (Scopus)
1994

Unique sequences in the guinea pig glucocorticoid receptor induce constitutive transactivation and decrease steroid sensitivity

Keightley, M. C. & Fuller, P. J., Apr 1994, In : Molecular Endocrinology. 8, 4, p. 431-439 9 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)
1991

Molecular cloning and sequencing of a guinea-pig pro-opiomelanocortin cDNA

Keightley, M. C., Funder, J. W. & Fuller, P. J., 1991, In : Molecular and Cellular Endocrinology. 82, 1, p. 89-98 10 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)