Projects per year
Personal profile
Biography
Cristina works at the Australian Regenerative Medicine Institute (ARMI) in the Faculty of Medicine, Nursing and Health Sciences at Monash University as a Research Fellow.
Biography
My current research program focuses on transcriptional regulation of myeloid development and disease.
We use zebrafish and mouse models to discover and understand molecular pathways in haematopoietic development. Within this context, we look at the role of transcription factors and mRNA splicing regulators, employing a multi-disciplinary approach integrating molecular genetics, biochemistry, genomics, and proteomics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Haemopoiesis
- Zebrafish
- Transcriptional Regulation
- Neutrophils
- White blood cell development
- Splicing
- Biochemistry and Cell Biology
- Transcription factors
- Transgenic Animals
- Genetics
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 5 Finished
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Fluorescent Fish: Installation of fluorescence microscopes for screening of fluorescent transgenic animals Fish/Aqua Core
Kaslin, J., Currie, P., Lieschke, G., Ramialison, M., Bryson-Richardson, R., Keightley, C., Peleg, A., Abud, H., McGlinn, E., Merson, T., Hobbs, R., Anko, M. & Bird, P.
1/12/16 → 31/12/17
Project: Research
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NHMRC Equipment Grant - Water filtration upgrade for cost effective water treatment in FishCore
Kaslin, J., Abud, H., Anko, M., Bryson-Richardson, R., Currie, P., Dworkin, S., Ferrero, R., Hobbs, R., Keightley, C., Lieschke, G., McGlinn, E., Peleg, A. & Ramialison, M.
National Health and Medical Research Council (NHMRC) (Australia)
5/12/14 → 31/12/15
Project: Research
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Zbtb11 interactions in haematopoiesis and disease
National Health and Medical Research Council (NHMRC) (Australia)
1/01/14 → 31/12/16
Project: Research
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Imaris 3D/4D image analysis software and workstations
Lieschke, G., Abud, H., Bourne, J., Currie, P., Dworkin, S., Harper, I., Heng, J., Hickey, M., Kaslin, J., Keightley, C., Marcelle, C., McGlinn, E., Peleg, A., Plachta, N., Risbridger, G., Rosenthal, N. & Sloan, E.
National Health and Medical Research Council (NHMRC) (Australia)
17/12/13 → 31/12/13
Project: Research
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Role of ZBTB11 in hepatocellular carcinoma
Lieschke, G., Gong, Z. & Keightley, C.
1/01/13 → 31/12/15
Project: Research
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Pioneer neutrophils release chromatin within in vivo swarms
Isles, H. M., Loynes, C. A., Alasmari, S., Kon, F. C., Henry, K. M., Kadochnikova, A., Hales, J., Muir, C. F., Keightley, M. C., Kadirkamanathan, V., Hamilton, N., Lieschke, G. J., Renshaw, S. A. & Elks, P. M., Jul 2021, In: eLife. 10, 29 p., e68755.Research output: Contribution to journal › Article › Research › peer-review
Open Access23 Citations (Scopus) -
Frontline Science: Dynamic cellular and subcellular features of migrating leukocytes revealed by in vivo lattice lightsheet microscopy
Manley, H. R., Potter, D. L., Heddleston, J. M., Chew, T-L., Keightley, M. C. & Lieschke, G. J., Aug 2020, In: Journal of Leukocyte Biology. 108, 2, p. 455-468 14 p.Research output: Contribution to journal › Article › Research › peer-review
16 Citations (Scopus) -
Splicing dysfunction and disease: The case of granulopoiesis
Keightley, M-C. & Lieschke, G. J., Mar 2018, In: Seminars in Cell & Developmental Biology. 75, p. 23-39 17 p.Research output: Contribution to journal › Review Article › Other › peer-review
2 Citations (Scopus) -
The Neutrophil Nucleus: An Important Influence on Neutrophil Migration and Function
Manley, H. R., Keightley, M. C. & Lieschke, G. J., 4 Dec 2018, In: Frontiers in Immunology. 9, 18 p., 2867.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile65 Citations (Scopus) -
A GCSFR/CSF3R zebrafish mutant models the persistent basal neutrophil deficiency of severe congenital neutropenia
Pazhakh, V., Clark, S., Keightley, M. C. & Lieschke, G. J., 10 Mar 2017, In: Scientific Reports. 7, 11 p., 44455.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile27 Citations (Scopus)