Projects per year
Personal profile
Biography
Cristina works at the Australian Regenerative Medicine Institute (ARMI) in the Faculty of Medicine, Nursing and Health Sciences at Monash University as a Research Fellow.
Biography
My current research program focuses on transcriptional regulation of myeloid development and disease.
We use zebrafish and mouse models to discover and understand molecular pathways in haematopoietic development. Within this context, we look at the role of transcription factors and mRNA splicing regulators, employing a multi-disciplinary approach integrating molecular genetics, biochemistry, genomics, and proteomics.
Keywords
- Haemopoiesis
- Zebrafish
- Transcriptional Regulation
- Neutrophils
- White blood cell development
- Splicing
- Biochemistry and Cell Biology
- Transcription factors
- Transgenic Animals
- Genetics
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2013 2017
- 5 Finished
Fluorescent Fish: Installation of fluorescence microscopes for screening of fluorescent transgenic animals Fish/Aqua Core
Kaslin, J., Currie, P., Lieschke, G., Ramialison, M., Bryson-Richardson, R., Keightley, C., Peleg, A., Abud, H., McGlinn, E., Merson, T., Hobbs, R., Anko, M. & Bird, P.
1/12/16 → 31/12/17
Project: Research
NHMRC Equipment Grant - Water filtration upgrade for cost effective water treatment in FishCore
Kaslin, J., Abud, H., Anko, M., Bryson-Richardson, R., Currie, P., Dworkin, S., Ferrero, R., Hobbs, R., Keightley, C., Lieschke, G., McGlinn, E., Peleg, A. & Ramialison, M.
National Health & Medical Research Council (NHMRC)
5/12/14 → 31/12/15
Project: Research
Zbtb11 interactions in haematopoiesis and disease
National Health & Medical Research Council (NHMRC)
1/01/14 → 31/12/16
Project: Research
Imaris 3D/4D image analysis software and workstations
Lieschke, G., Abud, H., Bourne, J., Currie, P., Dworkin, S., Harper, I., Heng, J., Hickey, M., Kaslin, J., Keightley, C., Marcelle, C., McGlinn, E., Peleg, A., Plachta, N., Risbridger, G., Rosenthal, N. & Sloan, E.
National Health & Medical Research Council (NHMRC)
17/12/13 → 31/12/13
Project: Research
Role of ZBTB11 in hepatocellular carcinoma
Lieschke, G., Gong, Z. & Keightley, C.
1/01/13 → 31/12/15
Project: Research
Research Output 1991 2018
Splicing dysfunction and disease: The case of granulopoiesis
Keightley, M-C. & Lieschke, G. J., Mar 2018, In : Seminars in Cell and Developmental Biology. 75, p. 23-39 17 p.Research output: Contribution to journal › Review Article › Other › peer-review
The Neutrophil Nucleus: An Important Influence on Neutrophil Migration and Function
Manley, H. R., Keightley, M. C. & Lieschke, G. J., 4 Dec 2018, In : Frontiers in Immunology. 9, 18 p., 2867.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
A GCSFR/CSF3R zebrafish mutant models the persistent basal neutrophil deficiency of severe congenital neutropenia
Pazhakh, V., Clark, S., Keightley, M. C. & Lieschke, G. J., 10 Mar 2017, In : Scientific Reports. 7, 11 p., 44455.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Intron retention enhances gene regulatory complexity in vertebrates
Schmitz, U., Pinello, N., Jia, F., Alasmari, S., Ritchie, W., Keightley, M-C., Shini, S., Lieschke, G. J., Wong, J. J. L. & Rasko, J. E. J., 16 Nov 2017, In : Genome Biology. 18, 1, 15 p., 216.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
MED12 in hematopoietic stem cells - Cell specific function despite ubiquitous expression: Cell specific function despite ubiquitous expression
Keightley, M-C., Nilsson, S. K. & Lieschke, G. J., 2017, In : Stem Cell Investigation. 2017, JAN, 3.Research output: Contribution to journal › Review Article › Other › peer-review
Open Access
File