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Research Output 1993 2018

Short Survey
289 Citations (Scopus)

Conservation of a sex-determining gene

Smith, C. A., McClive, P. J., Western, P. S., Reed, K. J. & Sinclair, A. H., 9 Dec 1999, In : Nature. 402, 6762, p. 601-602 2 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

11 Citations (Scopus)

Females Battle to Suppress Their Inner Male

Sinclair, A. & Smith, C., 11 Dec 2009, In : Cell. 139, 6, p. 1051-1053 3 p.

Research output: Contribution to journalShort SurveyResearchpeer-review

Review Article
4 Citations (Scopus)

Disorders of sexual development in poultry

Lambeth, L. S. & Smith, C. A., Feb 2012, In : Sexual Development. 6, 1-3, p. 96-103 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

15 Citations (Scopus)

Rowley review. Sex determination in birds: A review

Smith, C. A., 2010, In : Emu: Austral Ornithology. 110, 4, p. 364-377 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

223 Citations (Scopus)

Sex determination: Insights from the chicken

Smith, C. A. & Sinclair, A. H., 1 Feb 2004, In : BioEssays. 26, 2, p. 120-132 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
58 Citations (Scopus)

Sex determination and sexual differentiation in the avian model

Chue, J. & Smith, C. A., Apr 2011, In : FEBS Journal. 278, 7, p. 1027-1034 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

37 Citations (Scopus)

Sex determination in birds: HINTs from the W sex chromosome?

Smith, C. A., 1 Nov 2007, In : Sexual Development. 1, 5, p. 279-285 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

9 Citations (Scopus)

Sex reversal in birds

Major, A. T. & Smith, C. A., Dec 2016, In : Sexual Development. 10, 5-6, p. 288-300 13 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
File
7 Citations (Scopus)

The cell biology and molecular genetics of Müllerian duct development

Roly, Z. Y., Backhouse, B., Cutting, A. D., Tan, T. Y., Sinclair, A. H., Ayers, K. L., Major, A. T. & Smith, C. A., 1 May 2018, In : Wiley Interdisciplinary Reviews: Developmental Biology. 7, 3, 13 p., e310.

Research output: Contribution to journalReview ArticleResearchpeer-review

2 Citations (Scopus)

The cell biology and molecular genetics of testis determination.

Smith, C. A. & Sinclair, A. H., 1 Jan 2000, In : Results and Problems in Cell Differentiation. 28, p. 23-52 30 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

13 Citations (Scopus)

The molecular genetics of avian sex determination and its manipulation

Ayers, K. L., Smith, C. A. & Lambeth, L. S., May 2013, In : Genesis. 51, 5, p. 325-336 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

23 Citations (Scopus)

The molecular genetics of ovarian differentiation in the avian model

Ayers, K. L., Sinclair, A. H. & Smith, C. A., 2013, In : Sexual Development. 7, 1-3, p. 80-94 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Chapter (Book)
1 Citation (Scopus)

Genetic manipulation of the avian urogenital system using in ovo electroporation

Hirst, C. E., Serralbo, O., Ayers, K. L., Roeszler, K. N. & Smith, C. A., 2017, Avian and Reptilian Developmental Biology. Humana Press, Vol. 1650. p. 177-190 14 p. (Methods in Molecular Biology; vol. 1650).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

44 Citations (Scopus)

Short hairpin RNA-mediated gene silencing

Lambeth, L. S. & Smith, C. A., 2013, siRNA Design: Methods and Protocols. Taxman, D. J. (ed.). New York NY USA: Humana Press, Vol. 942. p. 205-232 28 p. (Methods in Molecular Biology; vol. 942).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Article
23 Citations (Scopus)

A comparative analysis of vertebrate sex determination

Sinclair, A., Smith, C., Western, P. & McClive, P., 1 Dec 2002, In : Novartis Foundation Symposium. 244, p. 102-114 13 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Anti-mullerian hormone is required for chicken embryonic urogenital system growth but not sexual differentiation

Lambeth, L. S., Ayers, K. L., Cutting, A. D., Doran, T. J., Sinclair, A. H. & Smith, C. A., 2015, In : Biology of Reproduction. 93, 6 (Art. No: 138), p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

Aromatase enzyme activity during gonadal sex differentiation in alligator embryos

Smith, C. A., Elf, P. K., Lang, J. W. & Joss, J. M. P., 1 Jan 1995, In : Differentiation. 58, 4, p. 281-290 10 p.

Research output: Contribution to journalArticleResearchpeer-review

92 Citations (Scopus)

Aromatase inhibition reduces expression of FOXL2 in the embryonic chicken ovary

Hudson, Q. J., Smith, C. A. & Sinclair, A. H., 1 Jul 2005, In : Developmental Dynamics. 233, 3, p. 1052-1055 4 p.

Research output: Contribution to journalArticleResearchpeer-review

91 Citations (Scopus)

ASW: a gene with conserved avian W-linkage and female specific expression in chick embryonic gonad

O'Neill, M., Binder, M., Smith, C., Andrews, J., Reed, K., Smith, M., Millar, C., Lambert, D. & Sinclair, A., 13 May 2000, In : Development Genes and Evolution. 210, 5, p. 243-249 7 p.

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)

Avian sex determination: What, when and where?

Smith, C. A., Roeszler, K. N., Hudson, Q. J. & Sinclair, A. H., 1 Jul 2007, In : Cytogenetic and Genome Research. 117, 1-4, p. 165-173 9 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Cloning and expression of a DAX1 homologue in the chicken embryo

Smith, C. A., Clifford, V., Western, P. S., Wilcox, S. A., Bell, K. S. & Sinclair, A. H., 1 Jan 2000, In : Journal of Molecular Endocrinology. 24, 1, p. 23-32 10 p.

Research output: Contribution to journalArticleResearchpeer-review

94 Citations (Scopus)

Cloning and expression of R-Spondin1 in different vertebrates suggests a conserved role in ovarian development

Smith, C. A., Shoemaker, C. M., Roeszler, K. N., Queen, J., Crews, D. & Sinclair, A. H., 1 Sep 2008, In : BMC Developmental Biology. 8, 72.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
6 Citations (Scopus)

Conserved expression of a novel gene during gonadal development

Hudson, Q. J., Smith, C. A. & Sinclair, A. H., 1 Jul 2005, In : Developmental Dynamics. 233, 3, p. 1083-1090 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
6 Citations (Scopus)

Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing

Farlie, P. G., Davidson, N. M., Baker, N. L., Raabus, M., Roeszler, K. N., Hirst, C., Major, A., Mariette, M. M., Lambert, D. M., Oshlack, A. & Smith, C. A., 1 Dec 2017, In : Nature Communications. 8, 1, 12 p., 132.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
86 Citations (Scopus)

Copy number variation in patients with disorders of sex development due to 46,XY gonadal dysgenesis

White, S. J., Ohnesorg, T., Notini, A., Roeszler, K., Hewitt, J., Daggag, H., Smith, C., Turbitt, E., Gustin, S., van den Bergen, J., Miles, D., Western, P., Arboleda, V., Schumacher, V., Gordon, L., Bell, K., Bengtsson, H., Speed, T., Hutson, J., Warne, G. L. & 4 others, Harley, V., Koopman, P., Vilain, E. & Sinclair, A., 2011, In : PLoS ONE. 6, 3, 10 p., e17793.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2 Citations (Scopus)

Development of retroviral vectors for tissue-restricted expression in chicken embryonic gonads

Lambeth, L. S., Ohnesorg, T., Cummins, D. M., Sinclair, A. H. & Smith, C. A., 8 Jul 2014, In : PLoS ONE. 9, 7, 11 p., e101811.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)

DMRT1 is required for mullerian duct formation in the chicken embryo

Ayers, K. L., Cutting, A. D., Roeszler, K. N., Sinclair, A. H. & Smith, C. A., 2015, In : Developmental Biology. 400, p. 224 - 236 13 p.

Research output: Contribution to journalArticleResearchpeer-review

126 Citations (Scopus)

DMRT1 is upregulated in the gonads during female-to-male sex reversal in ZW chicken embryos

Smith, C. A., Katz, M. & Sinclair, A. H., 1 Feb 2003, In : Biology of Reproduction. 68, 2, p. 560-570 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

ERRATUM TO: 'Identification of candidate gonadal sex differentiation genes in the chicken embryo using RNA-seq'

Ayers, K. L., Lambeth, L. S., Davidson, N. M., Sinclair, A. H., Oshlack, A. & Smith, C. A., 2016, In : BMC Genomics. 17, p. 169 - 169 1 p.

Research output: Contribution to journalArticleOther

14 Citations (Scopus)

Expression and evolutionary conservation of the tescalcin gene during development

Bao, Y., Hudson, Q. J., Perera, E. M., Akan, L., Tobet, S. A., Smith, C. A., Sinclair, A. H. & Berkovitz, G. D., 1 Jun 2009, In : Gene Expression Patterns. 9, 5, p. 273-281 9 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Expression of chicken steroidogenic factor-1 during gonadal sex differentiation

Smith, C. A., Smith, M. J. & Sinclair, A. H., 1 Jan 1999, In : General and Comparative Endocrinology. 113, 2, p. 187-196 10 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Expression profile of the RNA-binding protein gene hermes during chicken embryonic development

Wilmore, H. P., McClive, P. J., Smith, C. A. & Sinclair, A. H., 1 Jul 2005, In : Developmental Dynamics. 233, 3, p. 1045-1051 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
109 Citations (Scopus)

Gene expression during gonadogenesis in the chicken embryo

Smith, C. A., Smith, M. J. & Sinclair, A. H., 8 Jul 1999, In : Gene. 234, 2, p. 395-402 8 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Genetic evidence against a role for W-linked histidine triad nucleotide binding protein (HINTW) in avian sex determination

Smith, C. A., Roeszler, K. N. & Sinclair, A. H., 13 Jul 2009, In : International Journal of Developmental Biology. 53, 1, p. 59-67 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2 Citations (Scopus)

Gonadal and Endocrine Analysis of a Gynandromorphic Chicken

Morris, K. R., Hirst, C. E., Major, A. T., Ezaz, T., Ford, M., Bibby, S., Doran, T. J. & Smith, C. A., 1 Oct 2018, In : Endocrinology. 159, 10, p. 3492-3502 11 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Gonadal sex differentiation in Alligator mississippiensis, a species with temperature-dependent sex determination

Smith, C. A. & Joss, J. M. P., 1 Jul 1993, In : Cell and Tissue Research. 273, 1, p. 149-162 14 p.

Research output: Contribution to journalArticleResearchpeer-review

130 Citations (Scopus)

Gonadal sex differentiation in chicken embryos: Expression of estrogen receptor and aromatase genes

Smith, C. A., Andrews, J. E. & Sinclair, A. H., 1 Mar 1997, In : Journal of Steroid Biochemistry and Molecular Biology. 60, 5-6, p. 295-302 8 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Identification, expression, and regulation of anti-müllerian hormone type-II receptor in the embryonic chicken gonad

Cutting, A. D., Ayers, K., Davidson, N., Oshlack, A., Doran, T., Sinclair, A. H., Tizard, M. & Smith, C. A., 1 May 2014, In : Biology of Reproduction. 90, 5, 12 p., 106.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Identification of candidate gonadal sex differentiation genes in the chicken embryo using RNA-seq

Ayers, K. L., Lambeth, L. S., Davidson, N. M., Sinclair, A. H., Oshlack, A. & Smith, C. A., 2015, In : BMC Genomics. 16, 1 , 19 p., 704.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Immunohistochemical Localization of Laminin and Cytokeratin in Embryonic Alligator Gonads

Smith, C. A. & Joss, J. M. P., 1 Jan 1995, In : Acta Zoologica. 76, 3, p. 249-256 8 p.

Research output: Contribution to journalArticleResearchpeer-review

56 Citations (Scopus)

Just how conserved is vertebrate sex determination?

Cutting, A. D., Chue, J. & Smith, C. A., Apr 2013, In : Developmental Dynamics. 242, 4, p. 380-387 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Limb patterning genes and heterochronic development of the emu wing bud

Smith, C. A., Farlie, P. G., Davidson, N. M., Roeszler, K. N., Hirst, C., Oshlack, A. & Lambert, D. M., 20 Dec 2016, In : EvoDevo. 7, 1, 17 p., 26.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
39 Citations (Scopus)

Male-specific cell migration into the developing gonad is a conserved process involving PDGF signalling

Smith, C. A., McClive, P. J., Hudson, Q. & Sinclair, A. H., 15 Aug 2005, In : Developmental Biology. 284, 2, p. 337-350 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
37 Citations (Scopus)

Male-specific expression of Aldh1a1 in mouse and chicken fetal testes: Implications for retinoid balance in gonad development

Bowles, J., Feng, C. W., Knight, D., Smith, C. A., Roeszler, K. N., Bagheri-Fam, S., Harley, V. R., Sinclair, A. H. & Koopman, P., 1 Aug 2008, In : Developmental Dynamics. 238, 8, p. 2073-2080 8 p.

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

Manipulation of estrogen synthesis alters MIR202* expression in embryonic chicken gonads

Bannister, S. C., Smith, C. A., Roeszler, K. N., Doran, T. J., Sinclair, A. H. & Tizard, M. L. V., 1 Jul 2011, In : Biology of Reproduction. 85, 1, p. 22-30 9 p.

Research output: Contribution to journalArticleResearchpeer-review

82 Citations (Scopus)

Onset of meiosis in the chicken embryo; evidence of a role for retinoic acid

Smith, C. A., Roeszler, K. N., Bowles, J., Koopman, P. & Sinclair, A. H., 16 Oct 2008, In : BMC Developmental Biology. 8, 85.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
11 Citations (Scopus)

Overexpression of anti-mullerian hormone disrupts gonadal sex differentiation, blocks sex hormone synthesis, and supports cell autonomous sex development in the chicken

Lambeth, L. S., Morris, K., Ayers, K. L., Wise, T. G., O'Neil, T., Wilson, S., Cao, Y., Sinclair, A. H., Cutting, A. D., Doran, T. J. & Smith, C. A., Mar 2016, In : Endocrinology. 157, 3, p. 1258-1275 18 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Overexpression of Aromatase Alone is Sufficient for Ovarian Development in Genetically Male Chicken Embryos

Lambeth, L. S., Cummins, D. M., Doran, T. J., Sinclair, A. H. & Smith, C. A., 28 Jun 2013, In : PLoS ONE. 8, 6, e68362.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
49 Citations (Scopus)

Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads

Lambeth, L. S., Raymond, C. S., Roeszler, K. N., Kuroiwa, A., Nakata, T., Zarkower, D. & Smith, C. A., 15 May 2014, In : Developmental Biology. 389, 2, p. 160-172 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

Reconstruction and in vivo analysis of the extinct tbx5 gene from ancient wingless moa (Aves: Dinornithiformes)

Huynen, L., Suzuki, T., Ogura, T., Watanabe, Y., Millar, C. D., Hofreiter, M., Smith, C., Mirmoeini, S. & Lambert, D. M., 14 May 2014, In : BMC Evolutionary Biology. 14, 1, 8 p., 75.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File