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Research Output 1993 2018

11 Citations (Scopus)

Uptake of 3H‐estradiol by embryonic crocodile gonads during the period of sexual differentiation

Smith, C. A. & Joss, J. M. P., 1 Jan 1994, In : Journal of Experimental Zoology. 270, 2, p. 219-224 6 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Transgenic chickens overexpressing aromatase have high estrogen levels but maintain a predominantly male phenotype

Lambeth, L. S., Morris, K. R., Wise, T. G., Cummins, D. M., O'Neil, T. E., Cao, Y., Sinclair, A. H., Doran, T. J. & Smith, C. A., Jan 2016, In : Endocrinology. 157, 1, p. 83-90 8 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Third Report on Chicken Genes and Chromosomes 2015

Schmid, M., Smith, J., Burt, D. W., Aken, B. L., Antin, P. B., Archibald, A. L., Ashwell, C., Blackshear, P. J., Boschiero, C., Brown, C. T., Burgess, S. C., Cheng, H. H., Chow, W., Coble, D. J., Cooksey, A., Crooijmans, R. P. M. A., Damas, J., Davis, R. V. N., De Koning, D-J., Delany, M. E. & 83 others, Derrien, T., Desta, T. T., Dunn, I. C., Dunn, M., Ellegren, H., Eory, L. A., Erb, I., Farre, M., Fasold, M., Fleming, D., Flicek, P., Fowler, K. E., Fresard, L., Froman, D. P., Garceau, V., Gardner, P. P., Gheyas, A. A., Griffin, D. K., Groenen, M. A. M., Haaf, T., Hanotte, O. H., Hart, A. W., Hasler, J., Hedges, S. B., Hertel, J., Howe, K. L., Hubbard, A. J., Hume, D. A., Kaiser, P. C., Kedra, D. A., Kemp, S. J., Klopp, C., Kniel, K. E., Kuo, R., Lagarrigue, S., Lamont, S. J., Larkin, D. M., Lawal, R. A., Markland, S. M., McCarthy, F. M., McCormack, H. A., McPherson, M. C., Motegi, A., Muljo, S. A., Munsterberg, A. E., Nag, R., Nanda, I., Neuberger, M. S., Nitsche, A., Notredame, C., Noyes, H., O'Connor, R., O'Hare, E. A., Oler, A. J., Ommeh, S. C., Pais, H. C., Persia, M., Pitel, F., Preeyanon, L., Prieto Barja, P., Pritchett, E. M., Rhoads, D. D., Robinson, C. M., Romanov, M. N., Rothschild, M. F., Roux, P-F. F., Schmidt, C. J., Schneider, A-S. S., Schwartz, M. G., Searle, S. M. J., Skinner, M. A., Smith, C. A., Stadler, P. F., Steeves, T. E., Steinlein, C., Sun, L., Takata, M., Ulitsky, I., Wang, Q., Warren, W. C., Wood, J. M. D., Wragg, D. & Zhou, H., 2015, In : Cytogenetic and Genome Research. 145, 2, p. 78-179 102 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

The role of non-coding RNA in male sex determination and differentiation

Rastetter, R. H., Smith, C. A. & Wilhelm, D., 2015, In : Reproduction. 150, 3, p. 93 - 107 15 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

The potential role of microRNAs in regulating gonadal sex differentiation in the chicken embryo

Cutting, A. D., Bannister, S. C., Doran, T. J., Sinclair, A. H., Tizard, M. L. V. & Smith, C. A., Jan 2012, In : Chromosome Research. 20, 1, p. 201-213 13 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

The molecular genetics of ovarian differentiation in the avian model

Ayers, K. L., Sinclair, A. H. & Smith, C. A., 2013, In : Sexual Development. 7, 1-3, p. 80-94 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

13 Citations (Scopus)

The molecular genetics of avian sex determination and its manipulation

Ayers, K. L., Smith, C. A. & Lambeth, L. S., May 2013, In : Genesis. 51, 5, p. 325-336 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

34 Citations (Scopus)

The long non-coding RNA, MHM, plays a role in chicken embryonic development, including gonadogenesis

Roeszler, K. N., Itman, C. M., Sinclair, A. H. & Smith, C. A., 2012, In : Developmental Biology. 366, 2, p. 317 - 326 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

The cell biology and molecular genetics of testis determination.

Smith, C. A. & Sinclair, A. H., 1 Jan 2000, In : Results and Problems in Cell Differentiation. 28, p. 23-52 30 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

7 Citations (Scopus)

The cell biology and molecular genetics of Müllerian duct development

Roly, Z. Y., Backhouse, B., Cutting, A. D., Tan, T. Y., Sinclair, A. H., Ayers, K. L., Major, A. T. & Smith, C. A., 1 May 2018, In : Wiley Interdisciplinary Reviews: Developmental Biology. 7, 3, 13 p., e310.

Research output: Contribution to journalReview ArticleResearchpeer-review

414 Citations (Scopus)

The avian Z-linked gene DMRT1 is required for male sex determination in the chicken

Smith, C. A., Roeszler, K. N., Ohnesorg, T., Cummins, D. M., Farlie, P. G., Doran, T. J. & Sinclair, A. H., 10 Sep 2009, In : Nature. 461, 7261, p. 267-271 5 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Temporal and spatial expression profile of the novel armadillo-related gene, Alex2, during testicular differentiation in the mouse embryo

Smith, C. A., McClive, P. J. & Sinclair, A. H., 1 May 2005, In : Developmental Dynamics. 233, 1, p. 188-193 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
60 Citations (Scopus)

Steroidogenic enzyme activity and ovarian differentiation in the saltwater crocodile, Crocodylus porosus

Smith, C. A. & Joss, J. M. P., 1 Jan 1994, In : General and Comparative Endocrinology. 93, 2, p. 232-245 14 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Spatiotemporal expression patterns of doublesex and mab-3 related transcription factor 1 in the chicken developing gonads and Müllerian ducts

Omotehara, T., Smith, C. A., Mantani, Y., Kobayashi, Y., Tatsumi, A., Nagahara, D., Hashimoto, R., Hirano, T., Umemura, Y., Yokoyama, T., Kitagawa, H. & Hoshi, N., Apr 2014, In : British Poultry Science. 93, 4, p. 953-958 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
137 Citations (Scopus)

Sites of estrogen receptor and aromatase expression in the chicken embryo

Andrews, J. E., Smith, C. A. & Sinclair, A. H., 1 Jan 1997, In : General and Comparative Endocrinology. 108, 2, p. 182-190 9 p.

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

Short hairpin RNA-mediated gene silencing

Lambeth, L. S. & Smith, C. A., 2013, siRNA Design: Methods and Protocols. Taxman, D. J. (ed.). New York NY USA: Humana Press, Vol. 942. p. 205-232 28 p. (Methods in Molecular Biology; vol. 942).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

74 Citations (Scopus)

Sexually dimorphic microRNA expression during chicken embryonic gonadal development

Bannister, S. C., Tizard, M. L. V., Doran, T. J., Sinclair, A. H. & Smith, C. A., 1 Jul 2009, In : Biology of Reproduction. 81, 1, p. 165-176 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)

Sex reversal in birds

Major, A. T. & Smith, C. A., Dec 2016, In : Sexual Development. 10, 5-6, p. 288-300 13 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
File
9 Citations (Scopus)

Sex reversal and comparative data undermine the W chromosome and support Z-linked DMRT1 as the regulator of gonadal sex differentiation in birds

Hirst, C. E., Major, A. T., Ayers, K. L., Brown, R. J., Mariette, M., Sackton, T. B. & Smith, C. A., 1 Sep 2017, In : Endocrinology. 158, 9, p. 2970-2987 18 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Sex determination in the chicken embryo

Smith, C. A. & Sinclair, A. H., 1 Dec 2001, In : Journal of Experimental Zoology. 290, 7, p. 691-699 9 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Sex determination in birds: HINTs from the W sex chromosome?

Smith, C. A., 1 Nov 2007, In : Sexual Development. 1, 5, p. 279-285 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

58 Citations (Scopus)

Sex determination and sexual differentiation in the avian model

Chue, J. & Smith, C. A., Apr 2011, In : FEBS Journal. 278, 7, p. 1027-1034 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

6 Citations (Scopus)

Sex determination and gonadal sex differentiation in the chicken model

Hirst, C. E., Major, A. T. & Smith, C. A., 1 Jan 2018, In : International Journal of Developmental Biology. 62, 1-3, p. 153-166 14 p.

Research output: Contribution to journalArticleResearchpeer-review

223 Citations (Scopus)

Sex determination: Insights from the chicken

Smith, C. A. & Sinclair, A. H., 1 Feb 2004, In : BioEssays. 26, 2, p. 120-132 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
20 Citations (Scopus)

Sertoli cell differentiation and gonadogenesis in Alligator mississippiensis

Smith, C. A. & Joss, J. M. P., 1 Jan 1994, In : Journal of Experimental Zoology. 270, 1, p. 57-70 14 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Rowley review. Sex determination in birds: A review

Smith, C. A., 2010, In : Emu: Austral Ornithology. 110, 4, p. 364-377 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

23 Citations (Scopus)

Robust and ubiquitous GFP expression in a single generation of chicken embryos using the avian retroviral vector, RCASBP

Smith, C. A., Roeszler, K. N. & Sinclair, A. H., Jun 2009, In : Differentiation. 77, 5, p. 473-482 10 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

RNA sequencing reveals sexually dimorphic gene expression before gonadal differentiation in chicken and allows comprehensive annotation of the W-chromosome

Ayers, K. L., Davidson, N. M., Demiyah, D., Roeszler, K. N., Grützner, F., Sinclair, A. H., Oshlack, A. & Smith, C. A., 25 Mar 2013, In : Genome Biology. 14, 3, R26.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
17 Citations (Scopus)

Restricted expression of DMRT3 in chicken and mouse embryos

Smith, C. A., Hurley, T. M., McClive, P. J. & Sinclair, A. H., 1 Dec 2002, In : Mechanisms of Development. 119

Research output: Contribution to journalArticleResearchpeer-review

Open Access
5 Citations (Scopus)

Reconstruction and in vivo analysis of the extinct tbx5 gene from ancient wingless moa (Aves: Dinornithiformes)

Huynen, L., Suzuki, T., Ogura, T., Watanabe, Y., Millar, C. D., Hofreiter, M., Smith, C., Mirmoeini, S. & Lambert, D. M., 14 May 2014, In : BMC Evolutionary Biology. 14, 1, 8 p., 75.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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49 Citations (Scopus)

Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads

Lambeth, L. S., Raymond, C. S., Roeszler, K. N., Kuroiwa, A., Nakata, T., Zarkower, D. & Smith, C. A., 15 May 2014, In : Developmental Biology. 389, 2, p. 160-172 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
33 Citations (Scopus)

Overexpression of Aromatase Alone is Sufficient for Ovarian Development in Genetically Male Chicken Embryos

Lambeth, L. S., Cummins, D. M., Doran, T. J., Sinclair, A. H. & Smith, C. A., 28 Jun 2013, In : PLoS ONE. 8, 6, e68362.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
11 Citations (Scopus)

Overexpression of anti-mullerian hormone disrupts gonadal sex differentiation, blocks sex hormone synthesis, and supports cell autonomous sex development in the chicken

Lambeth, L. S., Morris, K., Ayers, K. L., Wise, T. G., O'Neil, T., Wilson, S., Cao, Y., Sinclair, A. H., Cutting, A. D., Doran, T. J. & Smith, C. A., Mar 2016, In : Endocrinology. 157, 3, p. 1258-1275 18 p.

Research output: Contribution to journalArticleResearchpeer-review

82 Citations (Scopus)

Onset of meiosis in the chicken embryo; evidence of a role for retinoic acid

Smith, C. A., Roeszler, K. N., Bowles, J., Koopman, P. & Sinclair, A. H., 16 Oct 2008, In : BMC Developmental Biology. 8, 85.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
44 Citations (Scopus)

Manipulation of estrogen synthesis alters MIR202* expression in embryonic chicken gonads

Bannister, S. C., Smith, C. A., Roeszler, K. N., Doran, T. J., Sinclair, A. H. & Tizard, M. L. V., 1 Jul 2011, In : Biology of Reproduction. 85, 1, p. 22-30 9 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Male-specific expression of Aldh1a1 in mouse and chicken fetal testes: Implications for retinoid balance in gonad development

Bowles, J., Feng, C. W., Knight, D., Smith, C. A., Roeszler, K. N., Bagheri-Fam, S., Harley, V. R., Sinclair, A. H. & Koopman, P., 1 Aug 2008, In : Developmental Dynamics. 238, 8, p. 2073-2080 8 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Male-specific cell migration into the developing gonad is a conserved process involving PDGF signalling

Smith, C. A., McClive, P. J., Hudson, Q. & Sinclair, A. H., 15 Aug 2005, In : Developmental Biology. 284, 2, p. 337-350 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
3 Citations (Scopus)

Limb patterning genes and heterochronic development of the emu wing bud

Smith, C. A., Farlie, P. G., Davidson, N. M., Roeszler, K. N., Hirst, C., Oshlack, A. & Lambert, D. M., 20 Dec 2016, In : EvoDevo. 7, 1, 17 p., 26.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
56 Citations (Scopus)

Just how conserved is vertebrate sex determination?

Cutting, A. D., Chue, J. & Smith, C. A., Apr 2013, In : Developmental Dynamics. 242, 4, p. 380-387 8 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Immunohistochemical Localization of Laminin and Cytokeratin in Embryonic Alligator Gonads

Smith, C. A. & Joss, J. M. P., 1 Jan 1995, In : Acta Zoologica. 76, 3, p. 249-256 8 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Identification of candidate gonadal sex differentiation genes in the chicken embryo using RNA-seq

Ayers, K. L., Lambeth, L. S., Davidson, N. M., Sinclair, A. H., Oshlack, A. & Smith, C. A., 2015, In : BMC Genomics. 16, 1 , 19 p., 704.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
13 Citations (Scopus)

Identification, expression, and regulation of anti-müllerian hormone type-II receptor in the embryonic chicken gonad

Cutting, A. D., Ayers, K., Davidson, N., Oshlack, A., Doran, T., Sinclair, A. H., Tizard, M. & Smith, C. A., 1 May 2014, In : Biology of Reproduction. 90, 5, 12 p., 106.

Research output: Contribution to journalArticleResearchpeer-review

130 Citations (Scopus)

Gonadal sex differentiation in chicken embryos: Expression of estrogen receptor and aromatase genes

Smith, C. A., Andrews, J. E. & Sinclair, A. H., 1 Mar 1997, In : Journal of Steroid Biochemistry and Molecular Biology. 60, 5-6, p. 295-302 8 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Gonadal sex differentiation in Alligator mississippiensis, a species with temperature-dependent sex determination

Smith, C. A. & Joss, J. M. P., 1 Jul 1993, In : Cell and Tissue Research. 273, 1, p. 149-162 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Gonadal and Endocrine Analysis of a Gynandromorphic Chicken

Morris, K. R., Hirst, C. E., Major, A. T., Ezaz, T., Ford, M., Bibby, S., Doran, T. J. & Smith, C. A., 1 Oct 2018, In : Endocrinology. 159, 10, p. 3492-3502 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Genetic manipulation of the avian urogenital system using in ovo electroporation

Hirst, C. E., Serralbo, O., Ayers, K. L., Roeszler, K. N. & Smith, C. A., 2017, Avian and Reptilian Developmental Biology. Humana Press, Vol. 1650. p. 177-190 14 p. (Methods in Molecular Biology; vol. 1650).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

28 Citations (Scopus)

Genetic evidence against a role for W-linked histidine triad nucleotide binding protein (HINTW) in avian sex determination

Smith, C. A., Roeszler, K. N. & Sinclair, A. H., 13 Jul 2009, In : International Journal of Developmental Biology. 53, 1, p. 59-67 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
109 Citations (Scopus)

Gene expression during gonadogenesis in the chicken embryo

Smith, C. A., Smith, M. J. & Sinclair, A. H., 8 Jul 1999, In : Gene. 234, 2, p. 395-402 8 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Females Battle to Suppress Their Inner Male

Sinclair, A. & Smith, C., 11 Dec 2009, In : Cell. 139, 6, p. 1051-1053 3 p.

Research output: Contribution to journalShort SurveyResearchpeer-review

13 Citations (Scopus)

Expression profile of the RNA-binding protein gene hermes during chicken embryonic development

Wilmore, H. P., McClive, P. J., Smith, C. A. & Sinclair, A. H., 1 Jul 2005, In : Developmental Dynamics. 233, 3, p. 1045-1051 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access