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Research Output 1993 2018

1993
45 Citations (Scopus)

Gonadal sex differentiation in Alligator mississippiensis, a species with temperature-dependent sex determination

Smith, C. A. & Joss, J. M. P., 1 Jul 1993, In : Cell and Tissue Research. 273, 1, p. 149-162 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1994
20 Citations (Scopus)

Sertoli cell differentiation and gonadogenesis in Alligator mississippiensis

Smith, C. A. & Joss, J. M. P., 1 Jan 1994, In : Journal of Experimental Zoology. 270, 1, p. 57-70 14 p.

Research output: Contribution to journalArticleResearchpeer-review

59 Citations (Scopus)

Steroidogenic enzyme activity and ovarian differentiation in the saltwater crocodile, Crocodylus porosus

Smith, C. A. & Joss, J. M. P., 1 Jan 1994, In : General and Comparative Endocrinology. 93, 2, p. 232-245 14 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Uptake of 3H‐estradiol by embryonic crocodile gonads during the period of sexual differentiation

Smith, C. A. & Joss, J. M. P., 1 Jan 1994, In : Journal of Experimental Zoology. 270, 2, p. 219-224 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1995
70 Citations (Scopus)

Aromatase enzyme activity during gonadal sex differentiation in alligator embryos

Smith, C. A., Elf, P. K., Lang, J. W. & Joss, J. M. P., 1 Jan 1995, In : Differentiation. 58, 4, p. 281-290 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Immunohistochemical Localization of Laminin and Cytokeratin in Embryonic Alligator Gonads

Smith, C. A. & Joss, J. M. P., 1 Jan 1995, In : Acta Zoologica. 76, 3, p. 249-256 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1997
130 Citations (Scopus)

Gonadal sex differentiation in chicken embryos: Expression of estrogen receptor and aromatase genes

Smith, C. A., Andrews, J. E. & Sinclair, A. H., 1 Mar 1997, In : Journal of Steroid Biochemistry and Molecular Biology. 60, 5-6, p. 295-302 8 p.

Research output: Contribution to journalArticleResearchpeer-review

137 Citations (Scopus)

Sites of estrogen receptor and aromatase expression in the chicken embryo

Andrews, J. E., Smith, C. A. & Sinclair, A. H., 1 Jan 1997, In : General and Comparative Endocrinology. 108, 2, p. 182-190 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1999
288 Citations (Scopus)

Conservation of a sex-determining gene

Smith, C. A., McClive, P. J., Western, P. S., Reed, K. J. & Sinclair, A. H., 9 Dec 1999, In : Nature. 402, 6762, p. 601-602 2 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

54 Citations (Scopus)

Expression of chicken steroidogenic factor-1 during gonadal sex differentiation

Smith, C. A., Smith, M. J. & Sinclair, A. H., 1 Jan 1999, In : General and Comparative Endocrinology. 113, 2, p. 187-196 10 p.

Research output: Contribution to journalArticleResearchpeer-review

109 Citations (Scopus)

Gene expression during gonadogenesis in the chicken embryo

Smith, C. A., Smith, M. J. & Sinclair, A. H., 8 Jul 1999, In : Gene. 234, 2, p. 395-402 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2000
91 Citations (Scopus)

ASW: a gene with conserved avian W-linkage and female specific expression in chick embryonic gonad

O'Neill, M., Binder, M., Smith, C., Andrews, J., Reed, K., Smith, M., Millar, C., Lambert, D. & Sinclair, A., 13 May 2000, In : Development Genes and Evolution. 210, 5, p. 243-249 7 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Cloning and expression of a DAX1 homologue in the chicken embryo

Smith, C. A., Clifford, V., Western, P. S., Wilcox, S. A., Bell, K. S. & Sinclair, A. H., 1 Jan 2000, In : Journal of Molecular Endocrinology. 24, 1, p. 23-32 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

The cell biology and molecular genetics of testis determination.

Smith, C. A. & Sinclair, A. H., 1 Jan 2000, In : Results and Problems in Cell Differentiation. 28, p. 23-52 30 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2001
51 Citations (Scopus)

Sex determination in the chicken embryo

Smith, C. A. & Sinclair, A. H., 1 Dec 2001, In : Journal of Experimental Zoology. 290, 7, p. 691-699 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2002
23 Citations (Scopus)

A comparative analysis of vertebrate sex determination

Sinclair, A., Smith, C., Western, P. & McClive, P., 1 Dec 2002, In : Novartis Foundation Symposium. 244, p. 102-114 13 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Restricted expression of DMRT3 in chicken and mouse embryos

Smith, C. A., Hurley, T. M., McClive, P. J. & Sinclair, A. H., 1 Dec 2002, In : Mechanisms of Development. 119

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2003
126 Citations (Scopus)

DMRT1 is upregulated in the gonads during female-to-male sex reversal in ZW chicken embryos

Smith, C. A., Katz, M. & Sinclair, A. H., 1 Feb 2003, In : Biology of Reproduction. 68, 2, p. 560-570 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2004
222 Citations (Scopus)

Sex determination: Insights from the chicken

Smith, C. A. & Sinclair, A. H., 1 Feb 2004, In : BioEssays. 26, 2, p. 120-132 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
2005
91 Citations (Scopus)

Aromatase inhibition reduces expression of FOXL2 in the embryonic chicken ovary

Hudson, Q. J., Smith, C. A. & Sinclair, A. H., 1 Jul 2005, In : Developmental Dynamics. 233, 3, p. 1052-1055 4 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Conserved expression of a novel gene during gonadal development

Hudson, Q. J., Smith, C. A. & Sinclair, A. H., 1 Jul 2005, In : Developmental Dynamics. 233, 3, p. 1083-1090 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
13 Citations (Scopus)

Expression profile of the RNA-binding protein gene hermes during chicken embryonic development

Wilmore, H. P., McClive, P. J., Smith, C. A. & Sinclair, A. H., 1 Jul 2005, In : Developmental Dynamics. 233, 3, p. 1045-1051 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
39 Citations (Scopus)

Male-specific cell migration into the developing gonad is a conserved process involving PDGF signalling

Smith, C. A., McClive, P. J., Hudson, Q. & Sinclair, A. H., 15 Aug 2005, In : Developmental Biology. 284, 2, p. 337-350 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
13 Citations (Scopus)

Temporal and spatial expression profile of the novel armadillo-related gene, Alex2, during testicular differentiation in the mouse embryo

Smith, C. A., McClive, P. J. & Sinclair, A. H., 1 May 2005, In : Developmental Dynamics. 233, 1, p. 188-193 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2007
43 Citations (Scopus)

Avian sex determination: What, when and where?

Smith, C. A., Roeszler, K. N., Hudson, Q. J. & Sinclair, A. H., 1 Jul 2007, In : Cytogenetic and Genome Research. 117, 1-4, p. 165-173 9 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Sex determination in birds: HINTs from the W sex chromosome?

Smith, C. A., 1 Nov 2007, In : Sexual Development. 1, 5, p. 279-285 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2008
93 Citations (Scopus)

Cloning and expression of R-Spondin1 in different vertebrates suggests a conserved role in ovarian development

Smith, C. A., Shoemaker, C. M., Roeszler, K. N., Queen, J., Crews, D. & Sinclair, A. H., 1 Sep 2008, In : BMC Developmental Biology. 8, 72.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
37 Citations (Scopus)

Male-specific expression of Aldh1a1 in mouse and chicken fetal testes: Implications for retinoid balance in gonad development

Bowles, J., Feng, C. W., Knight, D., Smith, C. A., Roeszler, K. N., Bagheri-Fam, S., Harley, V. R., Sinclair, A. H. & Koopman, P., 1 Aug 2008, In : Developmental Dynamics. 238, 8, p. 2073-2080 8 p.

Research output: Contribution to journalArticleResearchpeer-review

82 Citations (Scopus)

Onset of meiosis in the chicken embryo; evidence of a role for retinoic acid

Smith, C. A., Roeszler, K. N., Bowles, J., Koopman, P. & Sinclair, A. H., 16 Oct 2008, In : BMC Developmental Biology. 8, 85.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2009
14 Citations (Scopus)

Expression and evolutionary conservation of the tescalcin gene during development

Bao, Y., Hudson, Q. J., Perera, E. M., Akan, L., Tobet, S. A., Smith, C. A., Sinclair, A. H. & Berkovitz, G. D., 1 Jun 2009, In : Gene Expression Patterns. 9, 5, p. 273-281 9 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Females Battle to Suppress Their Inner Male

Sinclair, A. & Smith, C., 11 Dec 2009, In : Cell. 139, 6, p. 1051-1053 3 p.

Research output: Contribution to journalShort SurveyResearchpeer-review

28 Citations (Scopus)

Genetic evidence against a role for W-linked histidine triad nucleotide binding protein (HINTW) in avian sex determination

Smith, C. A., Roeszler, K. N. & Sinclair, A. H., 13 Jul 2009, In : International Journal of Developmental Biology. 53, 1, p. 59-67 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
23 Citations (Scopus)

Robust and ubiquitous GFP expression in a single generation of chicken embryos using the avian retroviral vector, RCASBP

Smith, C. A., Roeszler, K. N. & Sinclair, A. H., Jun 2009, In : Differentiation. 77, 5, p. 473-482 10 p.

Research output: Contribution to journalArticleResearchpeer-review

74 Citations (Scopus)

Sexually dimorphic microRNA expression during chicken embryonic gonadal development

Bannister, S. C., Tizard, M. L. V., Doran, T. J., Sinclair, A. H. & Smith, C. A., 1 Jul 2009, In : Biology of Reproduction. 81, 1, p. 165-176 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
411 Citations (Scopus)

The avian Z-linked gene DMRT1 is required for male sex determination in the chicken

Smith, C. A., Roeszler, K. N., Ohnesorg, T., Cummins, D. M., Farlie, P. G., Doran, T. J. & Sinclair, A. H., 10 Sep 2009, In : Nature. 461, 7261, p. 267-271 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
15 Citations (Scopus)

Rowley review. Sex determination in birds: A review

Smith, C. A., 2010, In : Emu: Austral Ornithology. 110, 4, p. 364-377 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2011
85 Citations (Scopus)

Copy number variation in patients with disorders of sex development due to 46,XY gonadal dysgenesis

White, S. J., Ohnesorg, T., Notini, A., Roeszler, K., Hewitt, J., Daggag, H., Smith, C., Turbitt, E., Gustin, S., van den Bergen, J., Miles, D., Western, P., Arboleda, V., Schumacher, V., Gordon, L., Bell, K., Bengtsson, H., Speed, T., Hutson, J., Warne, G. L. & 4 others, Harley, V., Koopman, P., Vilain, E. & Sinclair, A., 2011, In : PLoS ONE. 6, 3, 10 p., e17793.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
44 Citations (Scopus)

Manipulation of estrogen synthesis alters MIR202* expression in embryonic chicken gonads

Bannister, S. C., Smith, C. A., Roeszler, K. N., Doran, T. J., Sinclair, A. H. & Tizard, M. L. V., 1 Jul 2011, In : Biology of Reproduction. 85, 1, p. 22-30 9 p.

Research output: Contribution to journalArticleResearchpeer-review

58 Citations (Scopus)

Sex determination and sexual differentiation in the avian model

Chue, J. & Smith, C. A., Apr 2011, In : FEBS Journal. 278, 7, p. 1027-1034 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2012
4 Citations (Scopus)

Disorders of sexual development in poultry

Lambeth, L. S. & Smith, C. A., Feb 2012, In : Sexual Development. 6, 1-3, p. 96-103 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

32 Citations (Scopus)

The long non-coding RNA, MHM, plays a role in chicken embryonic development, including gonadogenesis

Roeszler, K. N., Itman, C. M., Sinclair, A. H. & Smith, C. A., 2012, In : Developmental Biology. 366, 2, p. 317 - 326 10 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

The potential role of microRNAs in regulating gonadal sex differentiation in the chicken embryo

Cutting, A. D., Bannister, S. C., Doran, T. J., Sinclair, A. H., Tizard, M. L. V. & Smith, C. A., Jan 2012, In : Chromosome Research. 20, 1, p. 201-213 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2013
56 Citations (Scopus)

Just how conserved is vertebrate sex determination?

Cutting, A. D., Chue, J. & Smith, C. A., Apr 2013, In : Developmental Dynamics. 242, 4, p. 380-387 8 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Overexpression of Aromatase Alone is Sufficient for Ovarian Development in Genetically Male Chicken Embryos

Lambeth, L. S., Cummins, D. M., Doran, T. J., Sinclair, A. H. & Smith, C. A., 28 Jun 2013, In : PLoS ONE. 8, 6, e68362.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
47 Citations (Scopus)

RNA sequencing reveals sexually dimorphic gene expression before gonadal differentiation in chicken and allows comprehensive annotation of the W-chromosome

Ayers, K. L., Davidson, N. M., Demiyah, D., Roeszler, K. N., Grützner, F., Sinclair, A. H., Oshlack, A. & Smith, C. A., 25 Mar 2013, In : Genome Biology. 14, 3, R26.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
43 Citations (Scopus)

Short hairpin RNA-mediated gene silencing

Lambeth, L. S. & Smith, C. A., 2013, siRNA Design: Methods and Protocols. Taxman, D. J. (ed.). New York NY USA: Humana Press, Vol. 942. p. 205-232 28 p. (Methods in Molecular Biology; vol. 942).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

13 Citations (Scopus)

The molecular genetics of avian sex determination and its manipulation

Ayers, K. L., Smith, C. A. & Lambeth, L. S., May 2013, In : Genesis. 51, 5, p. 325-336 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

23 Citations (Scopus)

The molecular genetics of ovarian differentiation in the avian model

Ayers, K. L., Sinclair, A. H. & Smith, C. A., 2013, In : Sexual Development. 7, 1-3, p. 80-94 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2014
2 Citations (Scopus)

Development of retroviral vectors for tissue-restricted expression in chicken embryonic gonads

Lambeth, L. S., Ohnesorg, T., Cummins, D. M., Sinclair, A. H. & Smith, C. A., 8 Jul 2014, In : PLoS ONE. 9, 7, 11 p., e101811.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
13 Citations (Scopus)

Identification, expression, and regulation of anti-müllerian hormone type-II receptor in the embryonic chicken gonad

Cutting, A. D., Ayers, K., Davidson, N., Oshlack, A., Doran, T., Sinclair, A. H., Tizard, M. & Smith, C. A., 1 May 2014, In : Biology of Reproduction. 90, 5, 12 p., 106.

Research output: Contribution to journalArticleResearchpeer-review