Projects per year
Personal profile
Biography
After completing his PhD at the University of New South Wales in 1999, Dr Harrison joined Prince Henry’s Institute in Melbourne. His postdoctoral training was at the Salk Institute for Biological Sciences (La Jolla, California) in the laboratory of Professor Wylie Vale as a NHMRC CJ Martin Training Fellow. On returning to Australia, he established the Growth Factor Signalling Laboratory at Prince Henry’s Institute (later the Hudson Institute). In 2016, Dr Harrison moved his lab to the Department of Physiology, Monash University.
Dr Harrison’s research focuses on the mechanisms underlying the synthesis and activation of TGF-β proteins, and the roles these growth factors play in skeletal muscle and the female reproductive system.
Dr Harrison has been a member of the ESA Council since 2014 and treasurer since 2017.
Supervision interests
Keywords
- Inhibin and activin
- muscle wasting
- folliculogenesis
- TGFbeta proteins
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2011 2020
Toward Precision Medicine for Cancer Cachexia
Harrison, C. A., Gregorevic, P. & Garcia, J.
1/01/18 → 31/12/20
Project: Research
Therapeutic potential of TGF-beta proteins for the diagnosis and treatment of female infertility
Gilchrist, R. & Harrison, C. A.
1/01/17 → 31/12/20
Project: Research
The importance of the blood-testis barrier in human infertility
Stanton, P., Harrison, C. A., Hedger, M. P. & McLachlan, R. I.
National Health & Medical Research Council (NHMRC)
1/01/17 → 31/12/19
Project: Research
Targeting activins to treat cachexia
Gregorevic, P., Harrison, C. A. & de Kretser, D. M.
National Health & Medical Research Council (NHMRC)
1/01/15 → 31/12/18
Project: Research
Research Output 1994 2018
Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy
Marini, K. , Croucher, D. R. , McCloy, R. A. , Vaghjiani, V. , Gonzalez-Rajal, A. , Hastings, J. F. , Chin, V. T. , Szczepny, A. , Kostyrko, K. , Marquez, C. , Jayasekara, W. S. N. , Alamgeer, M. , Boolell, V. , Han, J. Z. R. , Waugh, T. , Lee, H. C. , Oakes, S. R. , Kumar, B. , Harrison, C. A. , Hedger, M. P. & 13 others 25 Jul 2018 In : Science Translational Medicine. 10, 451, 13 p., eaat3504Research output: Contribution to journal › Article › Research › peer-review
Molecular characterization of latent GDF8 reveals mechanisms of activation
Walker, R. G., McCoy, J. C., Czepnik, M., Mills, M. J., Hagg, A., Walton, K. L., Cotton, T. R., Hyvönen, M., Lee, R. T., Gregorevic, P., Harrison, C. A. & Thompson, T. B. 30 Jan 2018 In : Proceedings of the National Academy of Sciences of the United States of America. 115, 5, p. E866-E875 10 p.Research output: Contribution to journal › Article › Research › peer-review
BMP15 mutations associated with primary ovarian insufficiency reduce expression, activity, or synergy with gdf9
Patino, L. C., Walton, K. L., Mueller, T. D., Johnson, K. E., Stocker, W., Richani, D., Agapiou, D., Gilchrist, R. B., Laissue, P. & Harrison, C. A. 1 Mar 2017 In : Journal of Clinical Endocrinology and Metabolism. 102, 3, p. 1009-1019 11 p.Research output: Contribution to journal › Article › Research › peer-review
Multiple soluble TGF-β receptors in addition to soluble endoglin are elevated in preeclamptic serum and they synergistically inhibit TGF-β signaling
Wang, Y., Chen, Q., Zhao, M., Walton, K., Harrison, C. & Nie, G. 1 Aug 2017 In : Journal of Clinical Endocrinology and Metablism. 102, 8, p. 3065-3074 10 p.Research output: Contribution to journal › Article › Research › peer-review
Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease
Chen, J., Walton, K. L., Hagg, A. G., Colgan, T. D., Johnson, K. E., Qian, H., Gregorevic, P. & Harrison, C. A. 27 Jun 2017 In : Proceedings of the National Academy of Sciences. 114, 26, p. E5266-E5275 10 p.Research output: Contribution to journal › Article › Research › peer-review