Projects per year
Personal profile
Biography
Associate Professor Cornelia Landersdorfer leads the Antimicrobial Pharmacokinetics, Pharmacodynamics and Dosage regimen optimisation research group at the Monash Institute of Pharmaceutical Sciences. She obtained her PhD in Pharmaceutical Sciences from the University of Wuerzburg (2006), completed postdoctoral studies in PK/PD modelling at the State University of New York (SUNY), and worked as a Scientist at Ordway Research Institute & the Institute for Clinical Pharmacodynamics (ICPD), NY. In 2011 she joined MIPS. She has since been awarded an NHMRC Career Development Fellowship and the ASCEPT Denis Wade J&J New Investigator Award. In 2018, Cornelia received the prestigious Georgina Sweet Award for Women in Quantitative Biomedical Science. In 2020 she was awarded the Faculty of Pharmacy and Pharmaceutical Sciences Research Impact award. She has led and is leading NHMRC Project and Ideas grants and is the Project Director of a large NIH clinical PK modelling contract.Associate Professor - Centre for Medicine Use and Safety.
In 2020, Cornelia joined the Monash Center to Impact AMR as a founding member and provides expert advice to our Research and Industry Strategy, Clinical Evaluation, and Training and Inclusion workkng groups.
Related Links:
Research interests
Antibiotic mono- and combination therapy to achieve synergistic bacterial killing and prevent resistance
Population pharmacokinetics, pharmacodynamics, and optimised dosage regimens of anti-infectives and other agents
Mechanism-based mathematical modelling
Tissue penetration into bone and other tissues
Mechanism-based population modelling of the glucose-insulin system, drug effects and disease progression in type 2 diabetes
Renal elimination mechanisms
Monash teaching commitment
BPS2041 Drug delivery and pharmacokinetics (second year Pharm Sci) - Unit coordinator and teaching pharmacokinetics
BPS3332 Applied pharmacokinetics/pharmacodynamics (third year Pharm Sci) - Unit coordinator and teaching pharmacokinetics/pharmacodynamics
Coordinating the CMUS PhD student training (CMUS HDR modules)
PHR1022 How Medicines Work II (first year Pharmacy) - teaching pharmacokinetics, pharmacogenomics, pharmacokinetics/pharmacodynamics
PhD student training in workshops on mechanism-based, population pharmacokinetic / pharmacodynamic modelling and simulation
Teaching applications of mechanism-based modelling to pharmaceutical industry
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Pharmaceutical Sciences, PhD, Modern pharmacokinetic / pharmacodynamic techniques to study physiological mechanisms of pharmacokinetic drug-drug interactions and disposition of antibiotics and to assess clinical relevance, Julius-Maximilians-Universität Würzburg (University of Wurzburg)
2002 → 2006
Award Date: 26 Sept 2006
Pharmacy and Pharmaceutical Sciences, BPharm, Universitat Regensburg (University of Regensburg)
1996 → 2001
External positions
Adjunct Associate Professor, University at Buffalo, State University of New York
15 Aug 2009 → …
Research area keywords
- Pharmacokinetics
- Pharmacodynamics
- Antimicrobial resistance
- Mathematical modelling
- Pharmacokinetics and Pharmacodynamics of Antibiotics
- Pseudomonas aeruginosa
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
Roberts, J. A., Slavin, M. A., Paterson, D. L., Comans, T. A., Lipman, J., Landersdorfer, C., Joynt, G., Bellomo, R., Clark, J. & Parker , S.
1/01/22 → 31/12/26
Project: Research
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Antibacterial Material Design via Mechanism-Based Mathematical Modelling
Whittaker, M., Landersdorfer, C. & Velkov, T.
31/01/20 → 31/12/23
Project: Research
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Overcoming multidrug-resistant hypermutable Pseudomonas aeruginosa via antibiotic combinations
Landersdorfer, C., Oliver, A., Harper, M. & Nation, R.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/12/23
Project: Research
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Novel dosing regimens to maximise antibiotic effectiveness for treatment of pneumonia in the intensive care unit
Roberts, J. A., Lipman, J., De Waele, J., Koulenti, D. & Landersdorfer, C.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/12/23
Project: Research
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Ceftolozane/tazobactam plus tobramycin against free-floating and biofilm bacteria of hypermutable Pseudomonas aeruginosa epidemic strains: Resistance mechanisms and synergistic activity
Agyeman, A. A., López-Causapé, C., Rogers, K. E., Lucas, D. D., Cortés-Lara, S., Gomis-Font, M. A., Fraile-Ribot, P., Figuerola, J., Lang, Y., Franklyn, E. R. T., Lee, W. L., Zhou, J., Zhang, Y., Bulitta, J. B., Boyce, J. D., Nation, R. L., Oliver, A. & Landersdorfer, C. B., Sept 2023, In: International Journal of Antimicrobial Agents. 62, 3, 10 p., 106887.Research output: Contribution to journal › Article › Research › peer-review
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Clinical pharmacological considerations in an early intravenous to oral antibiotic switch: are barriers real or simply perceived?
Landersdorfer, C. B., Gwee, A. & Nation, R. L., 11 Apr 2023, (Accepted/In press) In: Clinical Microbiology and Infection. 6 p.Research output: Contribution to journal › Review Article › Research › peer-review
2 Citations (Scopus) -
Evaluation of Empirical Dosing Regimens for Meropenem in Intensive Care Unit Patients Using Population Pharmacokinetic Modeling and Target Attainment Analysis
An, G., Creech, C. B., Wu, N., Nation, R. L., Gu, K., Nalbant, D., Jimenez-Truque, N., Fissell, W., Rolsma, S., Patel, P. C., Watanabe, A., Fishbane, N., Kirkpatrick, C. M. J., Landersdorfer, C. B. & Winokur, P., 24 Jan 2023, In: Antimicrobial Agents and Chemotherapy. 67, 1, 14 p., e0131222.Research output: Contribution to journal › Article › Research › peer-review
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iAMPCN: a deep-learning approach for identifying antimicrobial peptides and their functional activities
Xu, J., Li, F., Li, C., Guo, X., Landersdorfer, C. B., Shen, H-H., Peleg, A. Y., Li, J., Imoto, S., Yao, J., Akutsu, T. & Song, J., Jul 2023, In: Briefings in Bioinformatics. 24, 4, 20 p., bbad240.Research output: Contribution to journal › Article › Research › peer-review
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Population pharmacokinetics and target attainment analyses to identify a rational empirical dosing strategy for cefepime in critically ill patients
An, G., Creech, C. B., Wu, N., Nation, R. L., Gu, K., Nalbant, D., Jimenez-Truque, N., Fissell, W., Patel, P. C., Fishbane, N., Watanabe, A., Rolsma, S., Kirkpatrick, C. M. J., Landersdorfer, C. B. & Winokur, P., Jun 2023, In: Journal of Antimicrobial Chemotherapy. 78, 6, p. 1460-1470 11 p.Research output: Contribution to journal › Article › Research › peer-review
Prizes
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ASCEPT Denis Wade J&J New Investigator Award
Landersdorfer, Cornelia (Recipient), 2013
Prize: Prize (including medals and awards)
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Future Research Leader Award, Faculty of Pharmacy and Pharmaceutical Sciences
Landersdorfer, Cornelia (Recipient), 2016
Prize: Prize (including medals and awards)
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Georgina Sweet Award for Women in Quantitative Biomedical Science
Landersdorfer, Cornelia (Recipient), 8 Oct 2018
Prize: Prize (including medals and awards)
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Research Impact Award, Faculty of Pharmacy and Pharmaceutical Sciences
Landersdorfer, Cornelia (Recipient), 2020
Prize: Prize (including medals and awards)
Activities
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30th European Congress of Clinical Microbiology & Infectious Diseases
Cornelia Landersdorfer (Invited speaker)
Apr 2020 → …Activity: Participating in or organising an event types › Contribution to conference
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ASCEPT-PAGANZ conference
Cornelia Landersdorfer (Session chair)
25 Nov 2019Activity: Participating in or organising an event types › Contribution to conference
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Antimicrobial Agents and Chemotherapy (Journal)
Cornelia Landersdorfer (Editorial board member)
1 Jan 2019 → 31 Dec 2021Activity: Publication peer-review and editorial work types › Editorial responsibility
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Co-chair ASCEPT Drug Disposition and Response Special Interest Group
Cornelia Landersdorfer (Chair/ Co-Chair)
Nov 2019 → …Activity: External Academic Engagement › Professional association or peak discipline body
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Research Grant Reviewer, Office of the Chief Scientist, Scotland
Cornelia Landersdorfer (Reviewer)
2018 → …Activity: External Academic Engagement › Grant review responsibilities
Press/Media
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Radio interview on being a recipient of the Georgina Sweet Award for Women in Quantitative Biomedical Science
21/10/18
1 item of Media coverage
Press/Media: Profile/Interview
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Interview for documentary on superbugs - a different lens
25/05/18
1 item of Media coverage
Press/Media: Profile/Interview
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