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Con Sonza

Dr

20052016
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Research Output 2005 2016

2016

Increasing prevalence of K65K and K66K in HIV-1 subtype B reverse transcriptase

Telwatte, S., Brumme, C. J., Hearps, A. C., Latham, C. F. M., Hayward, J. A., Sonza, S., Sluis-Cremer, N., Harrigan, P. R. & Tachedjian, G., 28 Nov 2016, In : AIDS. 30, 18, p. 2787-2793 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2015
4 Citations (Scopus)

MYB elongation is regulated by the nucleic acid binding of NF?B p50 to the intronic stem-loop region

Pereira, L. A., Hugo, H. J., Malaterre, J., Xu, H., Sonza, S., Cures, A., Purcell, D. F. J., Ramsland, P. A., Gerondakis, S. D., Gonda, T. J. & Ramsay, R. G., 2015, In : PLoS ONE. 10, 4 (Art. No: e0122919), p. 1 - 25 25 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

Silent mutations at codons 65 and 66 in reverse transcriptase alleviate indel formation and restore fitness in subtype B HIV-1 containing D67N and K70R drug resistance mutations

Telwatte, S., Hearps, A. C., Johnson, A. P., Latham, C. F., Moore, K. A., Agius, P. A., Tachedjian, M., Sonza, S., Sluis-Cremer, N., Harrigan, P. R. & Tachedjian, G., 2015, In : Nucleic Acids Research. 43, 6, p. 3256 - 3271 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2013
65 Citations (Scopus)

Vaginal concentrations of lactic acid potently inactivate HIV

Aldunate, M. C., Tyssen, D., Johnson, A., Zakir, T. S., Sonza, S., Moench, T. R., Cone, R. & Tachedjian, G., 2013, In : Journal of Antimicrobial Chemotherapy. 68, 9, p. 2015 - 2025 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2012
70 Citations (Scopus)

Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions

Henriques, S. T., Huang, Y-H., Castanho, M. A. R. B., Bagatolli, L. A., Sonza, S., Tachedjian, G., Daly, N. L. & Craik, D. J., 2012, In : Journal of Biological Chemistry. 287, 40, p. 33629 - 33643 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2011
91 Citations (Scopus)

Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

Henriques, S. T., Huang, Y-H., Rosengren, J., Franquelim, H., Carvalho, F., Johnson, A., Sonza, S., Tachedjian, G., Castanho, M. A. R. B., Daly, N. & Craik, D., 2011, In : Journal of Biological Chemistry. 286, 27, p. 24231 - 24241 11 p.

Research output: Contribution to journalArticleResearchpeer-review

84 Citations (Scopus)

SPL7013 Gel (VivaGel) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans

Price, C. F., Tyssen, D., Sonza, S., Davie, A., Evans, S., Lewis, G. R., Xia, S., Spelman, T. D., Hodsman, P., Moench, T. R., Humberstone, A. J., Paull, J. RA. & Tachedjian, G., 2011, In : PLoS ONE. 6, 9, 12 p., e24095.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
64 Citations (Scopus)

Virucidal activity of the dendrimer microbicide SPL7013 against HIV-1

Telwatte, S., Moore, K., Johnson, A., Tyssen, D., Sterjovski, J., Aldunate, M., Gorry, P. R., Ramsland, P., Lewis, G., Paull, J., Sonza, S. & Tachedjian, G., 2011, In : Antiviral Research. 90, 3, p. 195 - 199 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
20 Citations (Scopus)

N348I in HIV-1 reverse transcriptase decreases susceptibility to tenofovir and etravirine in combination with other resistance mutations

Sluis-Cremer, N., Moore, K., Radzio, J., Sonza, S. & Tachedjian, G., 2010, In : AIDS. 24, 2, p. 317 - 319 3 p.

Research output: Contribution to journalArticleResearchpeer-review

104 Citations (Scopus)

Structure activity relationship of dendrimer microbicides with dual action antiviral activity

Tyssen, D., Henderson, S. A., Johnson, A., Sterjovski, J., Moore, K., La, J., Zanin, M. P., Sonza, S., Karellas, P., Giannis, M., Krippner, G. Y., Wesselingh, S. L., McCarthy, T. D., Gorry, P. R., Ramsland, P. A., Cone, R., Paull, J. RA., Lewis, G. R. & Tachedjian, G., 2010, In : PLoS ONE. 5, 8 (e12309), p. 1 - 15 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
8 Citations (Scopus)

Enhancement of human immunodeficiency virus type 1 replication is not intrinsic to all polyanion-based microbicides

Sonza, S., Johnson, A., Tyssen, D., Spelman, T. D., Lewis, G. R., Paull, J. R. A. & Tachedjian, G., 2009, In : Antimicrobial Agents and Chemotherapy. 53, 8, p. 3565 - 3568 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2008
44 Citations (Scopus)

HIV-1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages

Dowling, D., Nasr-Esfahani, S., Tan, C. H., O'Brien, K., Howard, J. L., Jans, D. A., Purcell, D. FJ., Stoltzfus, C. M. & Sonza, S., 2008, In : Retrovirology. 5, 18, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Primary T-lymphocytes rescue the replication of HIV-1 DIS RNA mutants in part by facilitating reverse transcription

Jones, K. L., Sonza, S. & Mak, J., 2008, In : Nucleic Acids Research. 36, 5, p. 1578 - 1588 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2007
67 Citations (Scopus)

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS

Sterjovski, J., Churchill, M., Ellett, A., Gray, L. R., Roche, M. J., Dunfee, R., Purcell, D. FJ., Saksena, N., Wang, B., Sonza, S., Wesselingh, S. L., Karlsson, I., Fenyo, E. M., Gabuzda, D., Cunningham, A. L. & Gorry, P. R., 2007, In : Retrovirology. 4, p. 1 - 21 21 p.

Research output: Contribution to journalArticleResearchpeer-review

64 Citations (Scopus)

CD16+ monocyte subset preferentially harbors HIV-1 and is expanded in pregnant Malawian women with Plasmodium falciparum malaria and HIV-1 infection

Jaworowski, A., Kamwendo, D. D., Ellery, P., Sonza, S., Mwapasa, V., Tadesse, E., Molyneux, M. E., Rogerson, S. J., Meshnick, S. R. & Crowe, S. M., 2007, In : Journal of Infectious Diseases. 196, 1, p. 38 - 42 5 p.

Research output: Contribution to journalArticleResearchpeer-review

223 Citations (Scopus)

The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo

Ellery, P., Tippett, E. D., Chiu, Y-L., Paukovics, G., Cameron, P. U., Solomon, A., Lewin, S. R., Gorry, P. R., Jaworowski, A., Greene, W. C., Sonza, S. & Crowe, S. M., 2007, In : Journal of Immunology. 178, 10, p. 6581 - 6589 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2006
19 Citations (Scopus)

Normal CD16 expression and phagocytosis of Mycobacterium avium complex by monocytes from a current cohort of HIV-1-infected patients

Jaworowski, A., Ellery, P., Maslin, C. L. V., Naim, E., Heinlein, A. C., Ryan, C. E., Paukovics, G., Hocking, J., Sonza, S. & Crowe, S. M., 2006, In : Journal of Infectious Diseases. 193, 5, p. 693 - 697 5 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

SerpinB2 Is an inducible host factor involved in enhancing HIV-1 transcription and replication

Darnell, G. A., Schroder, W. A., Gardner, J., Harrich, D., Yu, H., Medcalf, R. L., Warrilow, D., Antalis, T. M., Sonza, S. & Suhrbier, A., 2006, In : Journal of Biological Chemistry. 281, 42, p. 31348 - 31358 11 p.

Research output: Contribution to journalArticleResearchpeer-review

93 Citations (Scopus)

Use of laser capture microdissection to detect integrated HIV-1 DNA in macrophages and astrocytes from autopsy brain tissues

Churchill, M., Gorry, P. R., Cowley, D., Lal, L., Sonza, S., Purcell, D., Thompson, K. A., Gabuzda, D., McArthur, J., Pardo, C. A. & Wesselingh, S. L., 2006, In : Journal of Neurovirology. 12, 2, p. 146 - 152 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2005
6 Citations (Scopus)

Isolation of human immunodeficiency virus Type 1 from peripheral blood monocytes

Gorry, P. R., Sonza, S., Kedzierska, K. & Crowe, S. M., 2005, Methods in Molecular Biology - Human Retrovirus Protocols: Virology and Molecular Biology. Zhu, T. (ed.). 304 ed. USA: Humana Press, p. 25 - 33 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

46 Citations (Scopus)

Mutations that abrogate human immunodeficiency virus type 1 reverse transcriptase dimerization affect maturation of the reverse transcriptase heterodimer

Wapling, J. A., Moore, K. L., Sonza, S., Mak, J. & Tachedjian, G., 2005, In : Journal of Virology. 79, 16, p. 10247 - 10257 11 p.

Research output: Contribution to journalArticleResearchpeer-review