Con Si Lun Tam – Projects — Monash University

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EmailConstantine.Tammonashedu

Research activity per year

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1 Finished
1 Not started
14 Active

16 results

Active

A Phase 1/2, Open-Label, Multicenter, Dose Escalation and Cohort Expansion Study of the Safety and Efficacy of Anti-CD19 Allogeneic CRISPR-Cas9-Engineered T Cells (CTX112) in Subjects With Relapsed or Refractory B Cell Malignancies
Si Lun Tam, C. & Cheah, C.
4/08/23 → 4/08/25
Project: Research
A Phase 1 Open-Label, Multi-Center, Safety and Efficacy Study of PRT2527 in Participants with Relapsed/Refractory Hematologic Malignancies
Si Lun Tam, C. & Malherbe, M.
27/07/23 → 26/07/25
Project: Research
A Phase 1b/2, Open-Label, Safety and Efficacy Study of Epcoritamab (GEN3013; DuoBody®-CD3 X CD20) in Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter’s Syndrome
Si Lun Tam, C.
26/07/23 → 26/07/25
Project: Research
A Multicenter, Phase 1, Open-label, Dose-escalation and Expansion Study of TNB-486, a Bispecific Antibody Targeting CD19 in Subjects with Relapsed or Refractory B-Cell Non- Hodgkin Lymphoma
Si Lun Tam, C. & Kennedy, N.
17/07/23 → 16/07/25
Project: Research
Centre of Research Excellence in Chronic Lymphocytic Leukemia at the Victorian Comprehensive Cancer Centre – Studies into Cytokine Release Syndrome in CLL Patients.
Voskoboinik, I. & Si Lun Tam, C.
1/07/23 → 30/06/24
Project: Research
A Phase 3 Randomized, Open-Label, Multicenter Study of Zanubrutinib (BGB-3111) Plus Anti-CD20 Antibodies Versus Lenalidomide Plus Rituximab in Patients With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
Si Lun Tam, C.
17/04/23 → 1/06/26
Project: Research
A Phase 3 Randomized, Open-Label, Multicenter Study of Zanubrutinib (BGB-3111) Plus Anti-CD20 Antibodies Versus Lenalidomide Plus Rituximab in Patients with Relapsed/Refractory Follicular or Marginal Zone Lymphoma
Si Lun Tam, C. & Malherbe, M.
17/03/23 → 16/03/25
Project: Research
A Phase 3 Open-Label, Randomized Study of LOXO-305 versus Investigator’s Choice of Idelalisib plus Rituximab or Bendamustine plus Rituximab in BTK Inhibitor Pretreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-321)
Si Lun Tam, C. & Kennedy, N.
9/11/22 → 9/11/24
Project: Research
A Phase 3 Open-Label, Randomized Study of Fixed Duration Pirtobrutinib (LOXO-305) plus Venetoclax and Rituximab versus Venetoclax and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUINCLL- 322)
Si Lun Tam, C. & Kennedy, N.
2/11/22 → 1/11/24
Project: Research
A Phase 1, First-in-human Study of JNJ-80948543, a T-cell Redirecting Antibody, in Participants with NHL and CLL.
Si Lun Tam, C. & Kennedy, N.
28/09/22 → 26/02/26
Project: Research
A Phase 1/1b Open-Label Dose Escalation and Expansion Study of Bcl-2 Inhibitor BGB-11417 in Patients with Mature B- Cell Malignancies.
Si Lun Tam, C. & Kennedy, N.
27/05/22 → 31/12/26
Project: Research
A Phase 1, Open-Label, Dose-Escalation and -Expansion Study of the Bruton Tyrosine Kinase-Targeted Protein- Degrader BGB-16673 in Patients With B-Cell Malignancies.
Si Lun Tam, C. & Malherbe, M.
27/04/22 → 31/05/24
Project: Research
CLL Global Centre of Excellence in CLL Research
Si Lun Tam, C.
CLL Global Research Foundation
28/02/22 → 31/12/24
Project: Research
Understanding and Averting Blood Cancer Resistance to Therapy
Roberts, A. W., Blombery, P. A., Lam, E. Y. N. & Si Lun Tam, C.
1/01/22 → 31/12/26
Project: Research
Not started

A Phase 3 Open-Label, Randomized Study of Pirtobrutinib (LOXO- 305) versus Ibrutinib in Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN-CLL-314)
Si Lun Tam, C., Renwick, W., Johnston, A. M., Hahn, U. H. & Kennedy, N.
Project: Research
Finished

BH3-mimetics in rational combination therapies to overcome treatment-resistant cancers
Roberts, A. W., Wei, A., Si Lun Tam, C., Lindeman, G. J., Huang, D. C. S., Herold, M. J., Seymour, J. F., Mason, K. & Guthridge, M. A.
Victorian Cancer Agency
22/05/14 → 22/11/19
Project: Research