Projects per year
Personal profile
Biography
Professor of Pharmaceutical Biology, Theme Leader: Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences.
Faculty of Pharmacy and Pharmaceutical Sciences, Monash University (based at Monash Parkville Campus)
Research interests
- Use of stem cells, and cells derived by differentiation of stem cells, in drug discovery.
- Differentiation of pluripotent stem cells to derive brain cells (particularly neurons and microglia)
- Stem cell derived models of neurodegenerative diseases (Parkinsosn's and Alzheimer's diseases)
- Design and performance of delivery systems for nucleic acid therapeutics (DNA and RNA).
- Lipid-based delivery systems for oral delivery of poorly water-soluble drugs and oral peptides.
Monash teaching commitment
I have responsibility for teaching programs in our BPharm, new MPharm, and BPharm SCi degree programs. As a member of the Faculty Executive I assist in allocation of staff workload across various units.
I teach into units involving virology, biotechnology, formulations of small molecule drugs and biotech products, cancer biology and general methods in molecular biology.
I teach postgraduate students throughout the academic calendar year - currently I co-supervise 16 PhD students
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Developing an mRNA vaccine for the treatment of Alzheimer's disease
Nisbet, R. & Pouton, C.
21/07/23 → 31/12/25
Project: Research
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Development of novel mRNA products for clinical trials
Pouton, C., Beilharz, T., Carroll, J., Porter, C., Al-Wassiti, H., Davidovich, C., Johnston, A. & Trevaskis, N.
10/05/23 → 2/10/28
Project: Research
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RaRtech: a novel and rapid mRNA manufacturing technology for pandemics preparedness and therapeutics
Al-Wassiti, H., Pouton, C., Ho, J. & Teo, S.
mRNA Victoria, Monash University – Internal Faculty Contribution
21/10/22 → 30/05/24
Project: Research
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Improved glucose control, with lower insulin doses, for the treatment of type 1 diabetes
Cowley, M., Simonds, S., Thompson, P., Pouton, C. & Greenough, C.
MTP-IIGC Ltd (trading as MTP Connect)
1/08/22 → 15/09/24
Project: Research
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The Victorian Pre-clinical mRNA Innovation Incubator (VPMII)
Porter, C., Pouton, C., Carroll, J., Beilharz, T., Purcell, D. F. J., Caruso, F., Trevaskis, N., Johnston, A., Davidovich, C. & Knott, G.
23/06/22 → 22/06/25
Project: Research
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Molecular Dynamics Simulation Studies of Bile, Bile Salts, Lipid-Based Drug Formulations, and mRNA-Lipid Nanoparticles: A Review
Guruge, A. G., Warren, D. B., Pouton, C. W. & Chalmers, D. K., 17 May 2023, In: Molecular Pharmaceutics. 20, 6, p. 2781-2800 20 p.Research output: Contribution to journal › Review Article › Research › peer-review
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Targeting Melanocortin Receptors Using SNAr-Type Macrocyclization: A Doubly Orthogonal Route to Cyclic Peptide Conjugates
Yue, W. K., Zhang, T., Shandre Mugan, R., Barlow, N., Chalmers, D. K., Pouton, C. W. & Thompson, P. E., 21 Feb 2023, In: Journal of Medicinal Chemistry. 66, 5, p. 3273-3283 11 p.Research output: Contribution to journal › Article › Research › peer-review
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TGFβ3, dibutyryl cAMP and a notch inhibitor modulate phenotype late in stem cell-derived dopaminergic neuron maturation
Sibuea, S., Ho, J. K., Pouton, C. W. & Haynes, J. M., 1 Feb 2023, In: Frontiers in Cell and Developmental Biology. 11, 13 p., 1111705.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
In vivo delivery of plasmid DNA by lipid nanoparticles: the influence of ionizable cationic lipids on organ-selective gene expression
Algarni, A., Pilkington, E. H., Suys, E. J. A., Al-Wassiti, H., Pouton, C. W. & Truong, N. P., 7 Jun 2022, In: Biomaterials Science. 10, 11, p. 2940-2952 13 p.Research output: Contribution to journal › Article › Research › peer-review
23 Citations (Scopus) -
Polymeric Nanotubes as Drug Delivery Vectors-Comparison of Covalently and Supramolecularly Assembled Constructs
Kerr, A., Sagita, E., Mansfield, E. D. H., Nguyen, T. H., Feeney, O. M., Pouton, C. W., Porter, C. J. H., Sanchis, J. & Perrier, S., 13 Jun 2022, In: Biomacromolecules. 23, 6, p. 2315-2328 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus)
Activities
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Executive
Colin Pouton (Member)
2 Jan 2012Activity: External Academic Engagement › Grant review responsibilities
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Member
Colin Pouton (Member)
22 Sept 2011Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries