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Research Output 2005 2018

2018
9 Citations (Scopus)

miR-222 isoforms are differentially regulated by type-I interferon

Nejad, C., Pillman, K. A., Siddle, K. J., Pépin, G., Anko, M. L., McCoy, C. E., Beilharz, T. H., Quintana-Murci, L., Goodall, G. J., Bracken, C. P. & Gantier, M. P., 1 Mar 2018, In : RNA. 24, 3, p. 332-341 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Optimization techniques for miRNA expression in low frequency immune cell populations

Lyons, V. G., Payne, N. L. & McCoy, C. E., 1 Jan 2018, Inflammation and Cancer: Methods and Protocols. Jenkins, B. J. (ed.). New York, NY: Humana Press, p. 237-256 20 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2017
8 Citations (Scopus)

miR-155 dysregulation and therapeutic intervention in multiple sclerosis

McCoy, C. E., 2017, Regulation of Inflammatory Signaling in Health and Disease. Xu, D. (ed.). Singapore: Springer, p. 111-131 21 p. (Advances in Experimental Medicine and Biology; vol. 1024).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

2015
11 Citations (Scopus)

IL-10 regulates Aicda expression through miR-155

Fairfax, K., Gantier, M. P. M., Mackay-Fisson, F., Williams, B. R. G. & McCoy, C., 2015, In : Journal of leukocyte biology. 97, 1, p. 71 - 78 8 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors

Sarvestani, S., Stunden, H. J., Behlke, M. A., Forster, S., McCoy, C., Tate, M., Ferrand, J. F. P., Lennox, K. A., Latz, E., Williams, B. R. G. & Gantier, M. P. M., 30 Jan 2015, In : Nucleic Acids Research. 43, 2, p. 1177-1188 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2014
14 Citations (Scopus)

Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8

Sarvestani, S., Tate, M., Moffat, J. M., Jacobi, A. M., Behlke, M. A., Miller, A., Beckham, S. A., McCoy, C., Chen, W., Mintern, J., O'Keeffe, M., John, M., Williams, B. R. G. & Gantier, M. P. M., 2014, In : Journal of Virology. 88, 2, p. 799 - 810 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
33 Citations (Scopus)

The role of Ets2 transcription factor in the induction of microRNA-155 (miR-155) by lipopolysaccharide and its targeting by interleukin-10

Quinn, S. R., Mangan, N., Caffrey, B. E., Gantier, M. P. M., Williams, B. R. G., Hertzog, P. J., McCoy, C. & O'Neill, L. A. J., 2014, In : Journal of Biological Chemistry. 289, 7, p. 4316 - 4325 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2013
5 Citations (Scopus)

Conjugated linoleic acid suppresses IRF3 activation via modulation of CD14

Dowling, J. K., McCoy, C., Doyle, S. L., BenLarbi, N., Canavan, M., O'Neill, L. A. J. & Loscher, C. E., 2013, In : Journal of Nutritional Biochemistry. 24, 5, p. 920 - 928 9 p.

Research output: Contribution to journalLetterOther

55 Citations (Scopus)

miR-19a: an effective regulator of SOCS3 and enhancer of JAK-STAT signalling

Collins, A. S., McCoy, C., O'Farrelly, C. & Stevenson, N. J., 2013, In : PLoS ONE. 8, 7, 8 p., e69090.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2012

Alternative regulatory Mechanisms of TLR Signaling

McCoy, C., 2012, Nucleic Acid Sensors and Antiviral Immunity. Sambhara, S. & Fujita, T. (eds.). Second ed. United States: Landes Bioscience, p. 58 - 70 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

111 Citations (Scopus)

A miR-19 regulon that controls NF-{kappa}B signaling

Gantier, M. P. M., Stunden, H. J., McCoy, C., Behlke, M. A., Wang, D., Liaskos, M., Sarvestani, S., Yang, Y. H., Xu, D., Corr, S. C., Morand, E. F. & Williams, B. R. G., 2012, In : Nucleic Acids Research. 40, 16, p. 8048 - 8058 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
36 Citations (Scopus)

Characterization of the cellular action of the MSK inhibitor SB-747651A

Naqvi, S., Macdonald, A., McCoy, C., Darragh, J., Reith, A. & Arthur, J., 2012, In : Biochemical Journal. 441, 1, p. 347 - 357 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2011
236 Citations (Scopus)

Analysis of microRNA turnover in mammalian cells following Dicer1 ablation

Gantier, M., McCoy, C., Rusinova, I., Saulep, D., Wang, D., Xu, D., Irving, A., Behlke, M., Hertzog, P., Mackay-Fisson, F. & Williams, B., 2011, In : Nucleic Acids Research. 39, 13, p. 5692 - 5703 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
91 Citations (Scopus)

A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins

Ryan, A., Lynch, M., Smith, S., Amu, S., Nel, H., McCoy, C., Dowling, J. K., Draper, E., O'Reilly, V., McCarthy, C., O'Brien, J., Eidhin, D., O'Connell, M., Keogh, B., Morton, C., Rogers, T., Fallon, P., O'Neill, L., Kelleher, D. & Loscher, C., 2011, In : PLoS Pathogens. 7, 6 (Art. No: e1002076), 13 p., e1002076.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
541 Citations (Scopus)

MicroRNAs: The fine-tuners of Toll-like receptor signalling

O'Neill, L., Sheedy, F. & McCoy, C., 2011, In : Nature Reviews Immunology. 11, 3, p. 163 - 175 13 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

The role of miRNAs in cytokine signaling

McCoy, C., 2011, In : Frontiers in Bioscience. 17, p. 2161 - 2171 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
173 Citations (Scopus)

IL-10 inhibits miR-155 induction by Toll-like receptors

McCoy, C., Sheedy, F. J., Qualls, J. E., Doyle, S. L., Quinn, S. R., Murray, P. J. & O'Neill, L., 2010, In : Journal of Biological Chemistry. 285, 27, p. 20492 - 20498 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Methods in Molecular Biology: Toll-Like Receptors: Methods and Protocols

McCoy, C. & O'Neill, L., 2009, New York NY USA: Humana Press. 447 p.

Research output: Book/ReportEdited BookOther

2008
16 Citations (Scopus)

ERK5 regulation in naive T-cell activation and survival

Ananieva, O., Macdonald, A., Wang, X., McCoy, C., McIlrath, J., Tournier, C. & Arthur, J. S. C., 2008, In : European Journal of Immunology. 38, 9, p. 2534 - 2547 14 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Glucocorticoids inhibit IRF3 phosphorylation in response to Toll-like receptor-3 and -4 by targeting TBK1 activation

McCoy, C., Carpenter, S., Palsson-McDermott, E. M., Gearing, L. J. & O'Neill, L., 2008, In : Journal of Biological Chemistry. 283, 21, p. 14277 - 14285 9 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

The role of toll-like receptors in macrophages

McCoy, C. & O'Neill, L., 2008, In : Frontiers in Bioscience. 13, p. 62 - 70 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2007
40 Citations (Scopus)

Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS

McCoy, C., Macdonald, A., Morrice, N. A., Campbell, D. G., Deak, M., Toth, R., McIlrath, J. & Arthur, J. S. C., 2007, In : Biochemical Journal. 402, 3, p. 491 - 501 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2005
125 Citations (Scopus)

MSK1 activity is controlled by multiple phosphorylation sites

McCoy, C., Campbell, D. G., Deak, M., Bloomberg, G. B. & Arthur, J. S. C., 2005, In : Biochemical Journal. 387, Pt 2, p. 507 - 517 11 p.

Research output: Contribution to journalArticleResearchpeer-review