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Research Output 2008 2019

2019

6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity

Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.

Research output: Contribution to journalArticleResearchpeer-review

The effect of angiotensin AT1A inactivation on innate and learned fear responses in mice and its relationship to blood pressure

Choy, K. H. C., Chavez, C. A., Yu, J. & Mayorov, D. N., 1 Sep 2019, In : Psychoneuroendocrinology. 107, p. 208-216 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2018
7 Citations (Scopus)

Cognitive benefits of lithium chloride in APP/PS1 mice are associated with enhanced brain clearance of β-amyloid

Pan, Y., Short, J. L., Newman, S. A., Choy, K. H. C., Tiwari, D., Yap, C., Senyschyn, D., Banks, W. A. & Nicolazzo, J. A., May 2018, In : Brain, Behavior, and Immunity. 70, p. 36-47 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2016
19 Citations (Scopus)

Fatty acid-binding protein 5 at the blood–brain barrier regulates endogenous brain docosahexaenoic acid levels and cognitive function

Pan, Y., Short, J. L., Choy, K. H. C., Zeng, A. X., Marriott, P. J., Owada, Y., Scanlon, M. J., Porter, C. J. H. & Nicolazzo, J. A., 16 Nov 2016, In : Journal of Neuroscience. 36, 46, p. 11755-11767 13 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)
2014
16 Citations (Scopus)

Allosteric modulation of M1 muscarinic acetylcholine receptor internalization and subcellular trafficking

Yeatman, H. R., Lane, J. R. D., Choy, K. H. C., Lambert, N., Sexton, P., Christopoulos, A. & Canals, M., 2014, In : Journal of Biological Chemistry. 289, 22, p. 15856 - 15866 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2012
11 Citations (Scopus)

Analysis of vigilant scanning behavior in mice using two-point digital video tracking

Choy, K. H. C., Yu, J., Hawkes, D. & Mayorov, D. N., Jun 2012, In : Psychopharmacology. 221, 4, p. 649-657 9 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Long-term behavioral and NMDA receptor effects of young-adult corticosterone treatment in BDNF heterozygous mice

Klug, M., Hill, R. A., Choy, K. H. C., Kyrios, M., Hannan, A. C. & van den Buuse, M., Jun 2012, In : Neurobiology of Disease. 46, 3, p. 722 - 731 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
48 Citations (Scopus)
48 Citations (Scopus)

Effects of N-acetyl-cysteine treatment on glutathione depletion and a short-term spatial memory deficit in 2-cyclohexene-1-one-treated rats

Choy, K. H. C., Dean, O., Berk, M., Bush, A. I. & van den Buuse, M., Dec 2010, In : European Journal of Pharmacology. 649, 1-3, p. 224-228 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
42 Citations (Scopus)

The effect of 'two hit' neonatal and young-adult stress on dopaminergic modulation of prepulse inhibition and dopamine receptor density

Choy, K. H. C., De Visser, Y. P. & Van Den Buuse, M., Jan 2009, In : British Journal of Pharmacology. 156, 2, p. 388-396 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2008
33 Citations (Scopus)

Attenuated disruption of prepulse inhibition by dopaminergic stimulation after maternal deprivation and adolescent corticosterone treatment in rats

Choy, K. H. C. & van den Buuse, M., 1 Jan 2008, In : European Neuropsychopharmacology. 18, 1, p. 1-13 13 p.

Research output: Contribution to journalArticleResearchpeer-review

84 Citations (Scopus)

Combined neonatal stress and young-adult glucocorticoid stimulation in rats reduce BDNF expression in hippocampus: Effects on learning and memory

Choy, K. HC., de Visser, Y., Nichols, N. R. & van den Buuse, M., 2008, In : Hippocampus. 18, 7, p. 655 - 667 13 p.

Research output: Contribution to journalArticleResearchpeer-review