Projects per year
Personal profile
Biography
Dr. Christina GY has obtained her PhD from Monash University in 2012. In her PhD research project she explored candidate early predictors for diabetic nephropathy. Her hypothetical candidate early predictor for diabetic nephropathy risk is CYP2E1. In her post-doctoral projects she developed a targeted proteomic approach to quantitate CYP2E1 from human blood samples and assessed the applicability of this analytical method in clinical practice.
Her research interests are early biomolecules in the development of metabolic syndromes, drug metabolizing enzymes and obesity.
Dr. Christina's research expertise skills are HPLC, LCMS-MS, Genomics (Microarray analysis using Genespring and Partek softwares), Proteomics, Metabolomics, Bioinformatics and animal experimental models and cell culture models.
Currently she is an Associate Professor (Biomedical Sciences) at the School of Medicine, Monash University Malaysia in Kuala Lumpur Malaysia. She teaches Problem Based Learning (PBL), Histology, Physiology and Pharmacology into the MD and Bachelor of Pharmacy courses.
Research interests
- Pharmacokinetics and xenobiotic interaction with drug metabolizing enzymes.
- Development of early biomarkers in diabetic nephropathy.
- Translational studies of diabetic nephropathy.
- Teaching & Learning methods in medical education.
Research projects completed:
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Research Awards/Prizes won
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2009 Best Mention Award Evaluation of CYP2E1 Gene Expression in Diabetic Nephropathy using Quantitative Real Time PCR. 14th Biological Science Congress, Chulalongkorn University, Bangkok, Thailand, 10th-12th Dec.2009. 2014 Best Presentation Award Targeted CYP2E1 quantification: Research to Clinical Application. 5th World Congress on Diabetes and Metabolism, 3rd – 5th Nov 2014, Las Vegas, USA. 2017 1. First prize: Presentation Title: “The anthropometrics, cardio-metabolic health and oral microbiomes of an Indigenous tribe”. Monash CSJB research week 2017 2. Second runner-up: Presentation Title: “Endogenous molecules as candidate early indicator for type 2 diabetes” Monash CSJB research week 2017 3. Best Presentation Award: Title of Presentation: “Endogenous molecules as candidate early indicator for Pre-diabetes” 2nd World Congress on Clinical Trials in Diabetes, Berlin, Germany; 27-28th Nov 2017 |
Monash teaching commitment
2011 to date
- Physiology Lecturer: Year 1 and Year 2 MBBS/MD course.
- Coordinator & Facilitator: PBL sessions for Year 1 and 2 MD course
- Histology Tutor: Year 1 and Year 2 MBBS course
- Student Project Cases (SPC) Tutor: Year 2
- Pharmacology & Pharmacology Lecturer: Years 1, 2, 3 and 4;B. Pharmacy course
- Facilitator: IPE session Year 2 Pharmacy and MBBS students
- MD Year 5 - SIP Supervisions
- HDR supervision (PhD)
1993 – 2006
- Preparation and demonstration in practical classes for MBBS, BDS, pharmacy courses.
- Physiology and Pharmacology lectures for BPharm students.
- PBL Facilitator for BPharm students.
Leadersip duties in Education
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2005 Coordinator for Cancer chemotherapy unit, School of Pharmacy, IMU, PJ 2017 - Present Coordinator for Physiology, MBBS course, JCSMHS, MUM 2018 - Present Coordinator for Physiology, MBBS course, JCSMHS, MUM 2018 - Present Coordinator for Hematology, MBBS course, JCSMHS, MUM 2019 - Present MED1100 Year 1 PBL coordinator, MD course, JCSMHS, MUM 2019 - Present MED1100 Coordinator for Case Commentary Assignment, JCSMHS, MUM 2019 - Present Member of Student Support Committee, JCSMHS, MUM |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Graduate Certificate in Higher Education, GCHE, MONASH UNIVERSITY
Award Date: 18 Apr 2015
Biomedical Sciences, PhD, Candidate Early Predictors for Diabetic Nephropathy, MONASH UNIVERSITY
Award Date: 24 May 2012
External positions
Member, Malaysian Scientific Association
Member, Malaysian Society of Pharmacology & Physiology
Research area keywords
- Diabetic Nephropathy
- Obesity
- Diagnostic test
- Metabolic disorders
- Medical education
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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MMRPTT2D: Investigation of Molecular Mechanisms responsible for Renal Protection by supplementation with Tocotrienol-rich Fraction in a type 2 diabetes rat model
Yap, C. G. (Primary Chief Investigator (PCI)), Beatty, D. (Partner Investigator (PI)) & Narendra, P. (Chief Investigator (CI))
1/02/24 → 31/01/27
Project: Research
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Evaluation of anti-obesity activity on the natural Karanjin molecule through the adipogenesis pathway using a high-fat diet-induced rat model
Balasubramaniam, V. (Primary Chief Investigator (PCI)), binti Othman, R. (Chief Investigator (CI)), Subramaniyan, V. (Chief Investigator (CI)), Yap, C. G. (Chief Investigator (CI)), Seng, W. Y. (Chief Investigator (CI)) & Azlan, A. (Chief Investigator (CI))
1/10/23 → 30/09/26
Project: Research
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Investigation of the anticancer effects of alpha synuclein in lung cancer
Ng, K. Y. (Primary Chief Investigator (PCI)), Lee, S. W. H. (Chief Investigator (CI)), Koh, R. Y. (Chief Investigator (CI)), Chowdhury, M. E. H. (Chief Investigator (CI)), Othman, I. (Chief Investigator (CI)) & Yap, C. G. (Chief Investigator (CI))
1/09/19 → 30/11/23
Project: Research
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Neuroprotective and antioxidative nature of environmental enrichment exposure on diabetic and stressed rat hippocampus and identification of associated molecular pathways
Narendra, P. (Primary Chief Investigator (PCI)), Naidu, R. (Chief Investigator (CI)) & Yap, C. G. (Chief Investigator (CI))
1/08/16 → 31/07/18
Project: Research
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Assessment of self-management questionnaire in diabetes mellitus (ASQ-DM-EX) - the validation of novel lived experience inventory: Validation of novel lived experience inventory
Swarna Nantha, Y., Chung, K. R., Suresh, H. W. N., Heng, V. K. I., Yap, C. G., Tan, H. L., Lau, C. J., Soh, K. J., Babu, R. S. & Lim, J. X., Feb 2025, In: Family Practice. 42, 1, 8 p., cmaf003.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Strategies for optimization of hypoglycemia rat models
Zher, L. Y., Zheng, E. K. Q., Raymond, R. E., Jie, Y. Z. & Yap, C. G., Sept 2025, In: Animal Models and Experimental Medicine. 8, 9, p. 1590-1610 21 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access -
Environmental enrichment and the combined interventions of EE and metformin enhance hippocampal neuron survival and hippocampal-dependent memory in type 2 diabetic rats under stress through the BDNF-TrkB signaling pathways
Ismail, T. R., Yap, C. G., Naidu, R., Shri, L. & Pamidi, N., Jun 2024, In: Biomedicine & Pharmacotherapy. 175, 13 p., 116729.Research output: Contribution to journal › Article › Research › peer-review
Open Access13 Citations (Scopus) -
Environmental Enrichment and Metformin Improve Metabolic Functions, Hippocampal Neuron Survival, and Hippocampal-Dependent Memory in High-Fat/High-Sucrose Diet-Induced Type 2 Diabetic Rats
Ismail, T. R., Yap, C. G., Naidu, R. & Pamidi, N., Mar 2023, In: Biology. 12, 3, 22 p., 480.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile7 Citations (Scopus) -
Association between Social Network and Obesity among Adult Population
Lee, X. Y. B., Yusof, N. W., Pillai, N. K., Yap, C. G. & Jahan, N. K., Feb 2022, In: Open Journal of Endocrine and Metabolic Diseases. 12, 2, p. 20-46 27 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile
Prizes
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Endogenous molecules as candidate early indicator for Pre-diabetes
Yap, C. G. (Recipient), 28 Nov 2017
Prize: Prize (including medals and awards)
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Seed Grant Award
rabindranath, Y. (Recipient), Mariapun, J. (Recipient) & Yap, C. G. (Recipient), 2024
Prize: Prize (including medals and awards)
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