Projects per year
Personal profile
Biography
Christina is an Infectious Diseases physician-scientist and is internationally recognised for her clinical and research expertise in cryptococcal meningitis (CM) and cryptococcosis-associated immune reconstitution inflammatory syndrome (C-IRIS). She completed her medical degree and physician training in Melbourne, and has extensive international clinical experience, particularly in resource-limited settings. As part of her PhD on C-IRIS immunopathogenesis, she established a cohort of 130 HIV-CM co-infected persons in Durban, South Africa. She held an NHMRC Early career fellowship on HIV prevention and cure (2015-2020) and extended her international clinical trial experience working on investigational new agents for the treatment of COVID-19 (2020-current).
External positions
Senior Research Fellow for Clinical Trials and Cohorts, Kirby Institute
Mar 2020 → 31 Dec 2021
Honorary research associate, Centre for the AIDS Programme of Research in South Africa
2018 → …
Honorary Lecturer, University of KwaZulu-Natal
Apr 2012 → Apr 2015
Infectious Diseases Physician, Alfred Hospital
2011 → …
Research area keywords
- Cryptococcosis
- Immune reconstitution inflammatory Syndrome
- HIV/AIDS
- Fungal infections
- Opportunistic infections
- Cryptococcal meningitis
- Infection and immunity
- infections in immunocompromised hosts
- Infectious Disease
- COVID-19
- SARS-CoV-2
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 3 Finished
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Immunopathogenesis of cryptococcal meningitis and paradoxical cryptococcal meningitis immune restoration disease in persons living with HIV: Comparisons of immune responses in the central nervous syst
Chang, C., French, M. A. & Lewin, S.
Pfizer (Australia) (trading as Pfizer Australia Pty Limited)
1/06/11 → 31/05/12
Project: Research
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Cryptococcal Meningitis Immune Restoration Disease
Kidd, S., Chang, C. & Lewin, S.
1/11/09 → 31/10/10
Project: Research
Research output
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Comparative Immunogenicity and Effectiveness of mRNA-1273, BNT162b2, and Ad26.COV2.S COVID-19 Vaccines
Naranbhai, V., Garcia-Beltran, W. F., Chang, C. C., Berrios Mairena, C., Thierauf, J. C., Kirkpatrick, G., Onozato, M. L., Cheng, J., St Denis, K. J., Lam, E. C., Kaseke, C., Tano-Menka, R., Yang, D., Pavlovic, M., Yang, W., Kui, A., Miller, T. E., Astudillo, M. G., Cahill, J. E., Dighe, A. S. & 5 others, , 1 Apr 2022, In: Journal of Infectious Diseases. 225, 7, p. 1141-1150 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access15 Citations (Scopus) -
Design and implementation of an international, multi-arm, multi-stage platform master protocol for trials of novel SARS-CoV-2 antiviral agents: Therapeutics for Inpatients with COVID-19 (TICO/ACTIV-3)
Murray, D. D., Babiker, A. G., Baker, J. V., Barkauskas, C. E., Brown, S. M., Chang, C. C., Davey, V. J., Gelijns, A. C., Ginde, A. A., Grund, B., Higgs, E., Hudson, F., Kan, V. L., Lane, H. C., Murray, T. A., Paredes, R., Parmar, M. K. B., Pett, S., Phillips, A. N., Polizzotto, M. N. & 9 others, , Feb 2022, In: Clinical Trials. 19, 1, p. 52-61 10 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial
ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study Group, 1 May 2022, In: The Lancet Infectious Diseases. 22, 5, p. 622-635 14 p.Research output: Contribution to journal › Article › Research › peer-review
25 Citations (Scopus) -
Hyperimmune immunoglobulin for hospitalised patients with COVID-19 (ITAC): a double-blind, placebo-controlled, phase 3, randomised trial
The ITAC (INSIGHT 013) Study Group, 5 Feb 2022, In: The Lancet. 399, 10324, p. 530-540 11 p.Research output: Contribution to journal › Article › Research › peer-review
8 Citations (Scopus) -
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant
Garcia-Beltran, W. F., St. Denis, K. J., Hoelzemer, A., Lam, E. C., Nitido, A. D., Sheehan, M. L., Berrios, C., Ofoman, O., Chang, C. C., Hauser, B. M., Feldman, J., Roederer, A. L., Gregory, D. J., Poznansky, M. C., Schmidt, A. G., Iafrate, A. J., Naranbhai, V. & Balazs, A. B., 3 Feb 2022, In: Cell. 185, 3, p. 457-466.e4 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access219 Citations (Scopus)
Press / Media
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3RRR 102.7 radio interview – Zika virus and travel medicine, 24 July 2016
24/07/16
1 item of Media coverage
Press/Media: Public Engagement Activities
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JoyFM 94.9 radio interview – Sexually transmitted illnesses and the syphilis epidemic 18 August 2015
18/08/15
1 item of Media coverage
Press/Media: Public Engagement Activities
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JoyFM 94.9 radio interview - Treatment as prevention 17 February 2015
17/02/15
1 item of Media coverage
Press/Media: Public Engagement Activities
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Victorian AIDS council, Midsumma Hypothetical "MJ Loves Tina, Charlie's Chasing Harry", Melbourne Town Hall, 20 Jan 2015
20/01/15
1 item of Media coverage
Press/Media: Public Engagement Activities