Projects per year
Personal profile
Biography
Dr Christina Begka completed her undergraduate degree at the University of Ioannina in Greece. She performed her Masters in Medical Biology in the Department of Biochemistry at the University of Lausanne, Switzerland. Subsequently, she completed her PhD in the Immunology and Cancer at the University of Lausanne in Switzerland, where as part of her studies she was trained as a specialist in murine endoscopic and diagnostic procedures. Immediately after her PhD, Dr. Begka joined the Respiratory Immunology Group at Monash University on the Alfred Hospital precinct. Building upon her endoscopy expertise, Dr. Begka has established cutting-edge bronchoscopic methods for simulating fibrotic diseases (silicosis and IPF models) in mice that faithfully recapitulate human disease pathophysiology. Her current research in silicosis is supported by a 3-year Fellowship from the Dust Disease Board, iCare of NSW. Dr. Begka is also part of an NHMRC funded team that established a multi-omics analysis pipeline (lipidome, metabolome, gene expression) of broncho-alveolar lavage fluid from lung transplantation recipients at the Alfred Hospital, which is currently being employed to characterise the lung environment of these patients with a view to predicting lung allograft health trajectories.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Fibrosis
- Lung Fibrosis
- Lung Transplantation
- Endoscopy
- Bronchoscope
- Mouse endoscopy
Collaborations and top research areas from the last five years
Projects
- 1 Finished
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Multi-omics integration reveals a nonlinear signature that precedes progression of lung fibrosis
Pattaroni, C., Begka, C., Cardwell, B., Jaffar, J., Macowan, M., Harris, N. L., Westall, G. P. & Marsland, B. J., 2024, In: Clinical & Translational Immunology. 13, 1, 15 p., e1485.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Butyrate regulates neutrophil homeostasis and impairs early antimicrobial activity in the lung
Dang, A. T., Begka, C., Pattaroni, C., Caley, L. R., Floto, R. A., Peckham, D. G. & Marsland, B. J., Aug 2023, In: Mucosal Immunology. 16, 4, p. 476-485 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access9 Citations (Scopus) -
Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies
Oster, P., Vaillant, L., Riva, E., Mcmillan, B., Begka, C., Truntzer, C., Richard, C., Leblond, M. M., Messaoudene, M., Machremi, E., Limagne, E., Ghiringhelli, F., Routy, B., Verdeil, G. & Velin, D., Mar 2021, In: Gut. 71, 3, p. 457-466 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access114 Citations (Scopus) -
Toll-Interacting Protein Regulates Immune Cell Infiltration and Promotes Colitis-Associated Cancer
Begka, C., Pattaroni, C., Mooser, C., Nancey, S., Swiss IBD Cohort Study Group, McCoy, K. D., Velin, D. & Maillard, M. H., 27 Mar 2020, In: iScience. 23, 3, 13 p., 100891.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Citations (Scopus) -
Make (No) Bones about Butyrate
Begka, C. & Marsland, B. J., 18 Dec 2018, In: Immunity. 49, 6, p. 994-996 3 p.Research output: Contribution to journal › Short Survey › Other › peer-review
6 Citations (Scopus)