Research Output per year
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Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2014 2019
Conformational Transitions and the Activation of Heterotrimeric G Proteins by G Protein-Coupled Receptors
Draper-Joyce, C. & Furness, S. G. B., 26 Jul 2019, In : ACS Pharmacology and Translational Sciences. 2, 4, p. 285-290 6 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Molecular Determinants of the Intrinsic Efficacy of the Antipsychotic Aripiprazole
Klein Herenbrink, C., Verma, R., Lim, H. D., Kopinathan, A., Keen, A., Shonberg, J., Draper-Joyce, C. J., Scammells, P. J., Christopoulos, A., Javitch, J. A., Capuano, B., Shi, L. & Lane, J. R., 16 Aug 2019, In : ACS Chemical Biology. 14, 8, p. 1780-1792 13 p.Research output: Contribution to journal › Article › Research › peer-review
Subtle modifications to the indole-2-carboxamide motif of the negative allosteric modulator N-((trans)-4-(2-(7-cyano-3,4-dihydroisoquinolin-2(1 H)-yl)ethyl)cyclohexyl)-1 H-indole-2-carboxamide (SB269652) yield dramatic changes in pharmacological activity at the dopamine D2 receptor
Kopinathan, A., Draper-Joyce, C., Szabo, M., Christopoulos, A., Scammells, P. J., Lane, J. R. & Capuano, B., 1 Oct 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 371-377 7 p.Research output: Contribution to journal › Article › Research › peer-review
Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination
Liang, Y-L., Zhao, P., Draper-Joyce, C. J., Baltos, J-A., Glukhova, A., Truong, T. T., May, L. T., Christopoulos, A., Wootten, D., Sexton, P. & Furness, S., 2018, In : ACS Pharmacology and Translational Sciences. 1, 1, p. 12-20 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Recent advances in the determination of G protein-coupled receptor structures
Thal, D. M., Vuckovic, Z., Draper-Joyce, C. J., Liang, Y-L., Glukhova, A., Christopoulos, A. & Sexton, P. M., 1 Aug 2018, In : Current Opinion in Structural Biology. 51, p. 28-34 7 p.Research output: Contribution to journal › Article › Research › peer-review