Chong Lor Huai

EmailChong.LorHuaimonashedu

Accepting PhD Students

PhD projects

1. Development of organ-on-chip system to study cancer metastasis, and
2. Development of a 3D Breast Tumor-on-Chip Model as Alternative to
Animal Testing for Evaluating Liposome-Based Drug Delivery Systems

Research activity per year

Biography

Lor Huai Chong is an early-career researcher who has joined the School of Pharmacy, Monash University Malaysia as a lecturer since Sept 2021. She received her B.Eng and Ph.D. in Biomedical Engineering from Universiti Teknologi Malaysia (UTM), and the National University of Singapore(NUS) in 2014 and 2019 respectively. Before joining Monash University Malaysia, she did her post-doctoral training at the Bioinformatics Institute (BII), A*STAR, Singapore for 2 years.

Her research interest is to develop multi-scale tissue models to mimic the complex biological interactions, as well as translate them into scalable platforms for disease modeling and drug testing applications. During her Ph.D. candidature, her major scientific contribution is the development of in vitro tissue models to recapitulate cutaneous drug reactions. Her thesis work has resulted in several publications in the leading scientific journal(Q1, Top 10%), Lab on a Chip.

Lor Huai is also a recipient of the National University of Singapore(NUS) Research Scholarship, University Vice-Chancellor Award (UTM), Best of the Best Award in the Faculty’s Biosciences and Medical Engineering Student Conference (BME), and JPA scholarship(Malaysia).

Research interests

Micro-engineered tissue models to control and understand the cellular microenvironment for drug discovery and drug screening applications.
Development of 3D in vitro tumor microenvironment using organ-on-chip platform.

Monash teaching commitment

PHR1031 How The Body Works; Unit Coordinator

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

Education/Academic qualification

Biomedical Engineering, PhD, Development of in vitro models to predict cutaneous drug reactions, National University of Singapore (NUS)

1 Aug 2015 → 30 Jul 2019

Award Date: 30 Nov 2019

Biomedical Engineering, B.Eng (Hons), Universiti Teknologi Malaysia (University of Technology Malaysia)

1 Jul 2010 → 30 Jun 2014

Research area keywords

Organ on chip
Biophysics
Microfluidics
Cancer Cell Biology
Tissue engineering

4 Active

Identifying the Role of Soy Protein, Amway Exclusive Postbiotics, 2&3, BG3 and Phytonutrient DX in Supporting Gut Health
Lim, W. M. (Primary Chief Investigator (PCI)), Lor Huai, C. (Chief Investigator (CI)), Yong Sze, O. (Chief Investigator (CI)) & Chun Wie, C. (Chief Investigator (CI))
15/04/25 → 14/04/26
Project: Research
Determine the anti-inflammatory activities, transcriptomic and epigenetic profiling of postbiotics in colon epithelial cells
Lim, W. M. (Primary Chief Investigator (PCI)), Lor Huai, C. (Chief Investigator (CI)) & Yong Sze, O. (Chief Investigator (CI))
1/01/25 → 31/12/26
Project: Research
Development of a 3D Metastatic Breast Cancer-on-Chip Model for Evaluating Liposome-Based Drug Delivery Systems
Lor Huai, C. (Primary Chief Investigator (PCI)), Liang Ee, L. (Chief Investigator (CI)), Ogawa, S. (Chief Investigator (CI)), Ming Kwang, T. (Chief Investigator (CI)), Yong Sze, O. (Chief Investigator (CI)) & Chee, P. S. (Chief Investigator (CI))
1/09/23 → 31/08/25
Project: Research
Organ-on-chip: A potential biophysical modeling tool for cancer metastasis targeted-drug development
Lor Huai, C. (Primary Chief Investigator (PCI)), Hing, G. B. (Chief Investigator (CI)), Ogawa, S. (Chief Investigator (CI)), Siew Hua, G. (Chief Investigator (CI)), Toh, Y.-C. (Chief Investigator (CI)) & Chiam, K.-H. (Chief Investigator (CI))
1/09/22 → 28/02/26
Project: Research

10 Article
8 Conference Paper
2 Abstract
1 Conference article

Integration of a microfluidic multicellular coculture array with machine learning analysis to predict adverse cutaneous drug reactions
Chong, L. H., Ching, T., Farm, H. J., Grenci, G., Chiam, K.-H. & Toh, Y.-C., 21 May 2022, In: Lab on a Chip. 22, 10, p. 1890-1904 15 p.
Research output: Contribution to journal › Article › Research › peer-review

14 Citations (Scopus)
Engineering and measuring systemic multi-organ interactions for translational applications
Chong, L. H., Tan, H. Y., Ong, L., Tostado, C. & Toh, Y. C., 2020, MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, p. 11-12 2 p.
Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Other
A multi-culture array for modelling numerous mechanisms of cutaneous drug reactions
Chong, L. H., Ching, T., Grenci, G. & Toh, Y. C., 2020, MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, p. 931-932 2 p.
Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Other
A pump-free microfluidic 3D perfusion platform for the efficient differentiation of human hepatocyte-like cells
Ong, L. J. Y., Chong, L. H., Jin, L., Singh, P. K., Lee, P. S., Yu, H., Ananthanarayanan, A., Leo, H. L. & Toh, Y.-C., Oct 2017, In: Biotechnology and Bioengineering. 114, 10, p. 2360-2370 11 p.
Research output: Contribution to journal › Article › Research › peer-review

63 Citations (Scopus)
Liver-immune coculture array predicts drug-metabolism-induced skin sensitization
Chong, L. H., Li, H., Wetzel, I., Cho, H. & Toh, Y. C., 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, p. 167-170 4 p.
Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Other