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Research Output 2007 2019

2019

RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2

Zhang, Q., McKenzie, N. J., Warneford-Thomson, R., Gail, E. H., Flanigan, S. F., Owen, B. M., Lauman, R., Levina, V., Garcia, B. A., Schittenhelm, R. B., Bonasio, R. & Davidovich, C., 4 Mar 2019, In : Nature Structural and Molecular Biology. 26, 3, p. 237-247 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Structural basis of specific H2A K13/K15 ubiquitination by RNF168

Horn, V., Uckelmann, M., Zhang, H., Eerland, J., Aarsman, I., le Paige, U. B., Davidovich, C., Sixma, T. K. & van Ingen, H., 15 Apr 2019, In : Nature Communications. 10, 12 p., 1751.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2017

Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines

Wang, X., Goodrich, K. J., Gooding, A. R., Naeem, H., Archer, S., Paucek, R. D., Youmans, D. T., Cech, T. R. & Davidovich, C., 16 Mar 2017, In : Molecular Cell. 65, 6, p. 1056-1067 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Targeting PRC2: RNA offers new opportunities

Wang, X. & Davidovich, C., 1 Jan 2017, In : Oncotarget. 8, 64, p. 107346-107347 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel

Wekselman, I., Zimmerman, E., Davidovich, C., Belousoff, M., Matzov, D., Krupkin, M., Rozenberg, H., Bashan, A., Friedlander, G., Kjeldgaard, J., Ingmer, H., Lindahl, L., Zengel, J. M. & Yonath, A., 1 Aug 2017, In : Structure. 25, 8, p. 1233-1241 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Ribosomal antibiotics: Contemporary challenges

Auerbach-Nevo, T., Baram, D., Bashan, A., Belousoff, M., Breiner, E., Davidovich, C., Cimicata, G., Eyal, Z., Halfon, Y., Krupkin, M., Matzov, D., Metz, M., Rufayda, M., Peretz, M., Pick, O., Pyetan, E., Rozenberg, H., Shalev-Benami, M., Wekselman, I., Zarivach, R. & 11 othersZimmerman, E., Assis, N., Bloch, J., Israeli, H., Kalaora, R., Lim, L., Sade-Falk, O., Shapira, T., Taha-Salaime, L., Tang, H. & Yonath, A., 1 Sep 2016, In : Antibiotics. 5, 3, 24.

Research output: Contribution to journalReview ArticleResearchpeer-review

RNA duplex map in living cells reveals higher-order transcriptome structure

Lu, Z., Zhang, Q. C., Lee, B., Flynn, R. A., Smith, M. A., Robinson, J. T., Davidovich, C., Gooding, A. R., Goodrich, K. J., Mattick, J. S., Mesirov, J. P., Cech, T. R. & Chang, H. Y., 19 May 2016, In : Cell. 165, 5, p. 1267-1279 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2.

Davidovich, C. & Cech, T. R., 2015, In : Rna-A Publication of the Rna Society. 21, 12, p. 2007 - 2022 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Toward a consensus on the binding specificity and promiscuity of PRC2 for RNA

Davidovich, C., Wang, X., Cifuentes-Rojas, C., Goodrich, K. J., Lee, J. T., Gooding, A. R. & Cech, T. R., 2015, In : Molecular Cell. 57, 3, p. 552 - 558 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

A dimeric state for PRC2

Davidovich, C., Goodrich, K. J., Gooding, A. R. & Cech, T. R., 18 Aug 2014, In : Nucleic Acids Research. 42, 14, p. 9236-9248 13 p., gku540.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2013

Promiscuous RNA binding by Polycomb repressive complex 2

Davidovich, C., Zheng, L., Goodrich, K. J. & Cech, T. R., 2013, In : Nature Structural and Molecular Biology. 20, 11, p. 1250 - 1257 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

Ancient machinery embedded in the contemporary ribosome

Belousoff, M., Davidovich, C., Zimmerman, E., Caspi, Y., Wekselman, I., Rozenszajn, L., Shapira, T., Sade-Falk, O., Taha, L., Bashan, A., Weiss, M. & Yonath, A., 2010, In : Biochemical Society Transactions. 38, 2, p. 422 - 427 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Linking the RNA world to modern life: The proto-ribosome conception

Bashan, A., Belousoff, M. J., Davidovich, C. & Yonath, A., 2010, In : Origins of Life and Evolution of Biospheres. 40, 4, p. 425-429 5 p.

Research output: Contribution to journalArticleResearchpeer-review

On the development towards the modern world: A plausible role of uncoded peptides in the rnaworld

Belousoff, M. J., Davidovich, C., Bashan, A. & Yonath, A., 2010, In : Origins of Life and Evolution of Biospheres. 40, 4, p. 415-420 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The heat shock protein YbeY is required for optimal activity of the 30S ribosomal subunit

Rasouly, A., Davidovich, C. & Ron, E. Z., Sep 2010, In : Journal of Bacteriology. 192, 18, p. 4592-4596 5 p.

Research output: Contribution to journalArticleResearchpeer-review

The proto-ribosome: An ancient nano-machine for peptide bond formation

Davidovich, C., Belousoff, M., Wekselman, I., Shapira, T., Krupkin, M., Zimmerman, E., Bashan, A. & Yonath, A., 18 Jun 2010, In : Israel Journal of Chemistry. 50, 1, p. 29-35 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics

Auerbach, T., Mermershtain, I., Davidovich, C., Bashan, A., Belousoff, M., Wekselman, I., Zimmerman, E., Xiong, L., Klepacki, D., Arakawa, K., Kinashi, H., Mankin, A. & Yonath, A., 2010, In : Proceedings of the National Academy of Sciences. 107, 5, p. 1983 - 1988 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Ribosome's mode of function: Myths, facts and recent results

Wekselman, I., Davidovich, C., Agmon, I., Zimmerman, E., Rozenberg, H., Bashan, A., Berisio, R. & Yonath, A., 2009, In : Journal of Peptide Science. 15, 3, p. 122-130 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin

Auerbach-Nevo, T., Mermershtain, I., Bashan, A., Davidovich, C., Rozenberg, H., Sherman, D. H. & Yonath, A., 2009, In : Biotechnologia. 1, p. 24-35 12 p.

Research output: Contribution to journalArticleResearchpeer-review

The evolving ribosome: from non-coded peptide bond formation to sophisticated translation machinery

Davidovich, C., Belousoff, M., Bashan, A. & Yonath, A., 2009, In : Research in Microbiology. 160, 7, p. 487 - 492 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2008

Structural basis for cross-resistance to ribosomal PTC antibiotics

Davidovich, C., Bashan, A. & Yonath, A., 2008, In : Proceedings of the National Academy of Sciences. 105, 52, p. 20665 - 20670 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity

Davidovich, C., Bashan, A., Auerbach-Nevo, T., Yaggie, R. D., Yonath, A. & Gontarek, R. R., 2007, In : Proceedings of the National Academy of Sciences. 104, 11, p. 4291 - 4296 6 p.

Research output: Contribution to journalArticleResearchpeer-review