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Personal profile

Research interests

The Davidovich Group aims to understand the detailed molecular events that underlie the recruitment and regulation of chromatin-modifying complexes by their co-factor proteins, RNAs and DNA. For more information, see the Davidovich Lab website: http://www.davidovich-lab.com/

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Projects 2016 2021

Research Output 2007 2019

RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2

Zhang, Q., McKenzie, N. J., Warneford-Thomson, R., Gail, E. H., Flanigan, S. F., Owen, B. M., Lauman, R., Levina, V., Garcia, B. A., Schittenhelm, R. B., Bonasio, R. & Davidovich, C., 4 Mar 2019, In : Nature Structural and Molecular Biology. 26, 3, p. 237-247 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Structural basis of specific H2A K13/K15 ubiquitination by RNF168

Horn, V., Uckelmann, M., Zhang, H., Eerland, J., Aarsman, I., le Paige, U. B., Davidovich, C., Sixma, T. K. & van Ingen, H., 15 Apr 2019, In : Nature Communications. 10, 12 p., 1751.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines

Wang, X., Goodrich, K. J., Gooding, A. R., Naeem, H., Archer, S., Paucek, R. D., Youmans, D. T., Cech, T. R. & Davidovich, C., 16 Mar 2017, In : Molecular Cell. 65, 6, p. 1056-1067 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Targeting PRC2: RNA offers new opportunities

Wang, X. & Davidovich, C., 1 Jan 2017, In : Oncotarget. 8, 64, p. 107346-107347 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel

Wekselman, I., Zimmerman, E., Davidovich, C., Belousoff, M., Matzov, D., Krupkin, M., Rozenberg, H., Bashan, A., Friedlander, G., Kjeldgaard, J., Ingmer, H., Lindahl, L., Zengel, J. M. & Yonath, A., 1 Aug 2017, In : Structure. 25, 8, p. 1233-1241 9 p.

Research output: Contribution to journalArticleResearchpeer-review