Projects per year
Personal profile
Research interests
The Davidovich Group aims to understand the detailed molecular events that underlie the recruitment and regulation of chromatin-modifying complexes by their co-factor proteins, RNAs and DNA. For more information, see the Davidovich Lab website: http://www.davidovich-lab.com/
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Projects 2016 2021
RNA-mediated regulation of the histone methyltransferase PRC2: a new link to disease-associated and causing mutations
1/01/19 → 31/12/21
Project: Research
Identifying the function of nucleic acid binding by the PRC2 accessory protein JARID2.
Davidovich, C. & McKenzie, N.
22/02/18 → 13/09/21
Project: Research
Tapping the power of pluripotency: The role of HMGA1 protein in stem cell renewal and cell fate transitions.
Anko, M., Kaslin, J., Davidovich, C. & Ramialison, M.
1/01/18 → 31/12/20
Project: Research
Statistical Methods for Cut Point Analysis in Immunogenicity Assays
Davidovich, C. & Gail, E.
15/04/19 → 16/08/19
Project: Research
Beckman Coulter Optima Analytical Ultracentrifuge (AUC)
Dunstone, M., Whisstock, J., Daly, R., Atkinson, S., Turner, S., Lithgow, T., Gras, S., Stone, M., Davidovich, C., Rood, J., Coulibaly, F., Wilce, J., Borg, N., McGowan, S., Buckle, A., Elmlund, D., Elmlund, H., Belousoff, M., Ellisdon, A., Law, R., Purcell, A., Cryle, M., Nold, M., Nold, C., Warr, C., Johnson, T., Henstridge, M., Aguilar, M., Stroud, D. & Ryan, M.
1/12/16 → 31/12/17
Project: Research
Research Output 2007 2019
RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2
Zhang, Q., McKenzie, N. J., Warneford-Thomson, R., Gail, E. H., Flanigan, S. F., Owen, B. M., Lauman, R., Levina, V., Garcia, B. A., Schittenhelm, R. B., Bonasio, R. & Davidovich, C., 4 Mar 2019, In : Nature Structural and Molecular Biology. 26, 3, p. 237-247 11 p.Research output: Contribution to journal › Article › Research › peer-review
Structural basis of specific H2A K13/K15 ubiquitination by RNF168
Horn, V., Uckelmann, M., Zhang, H., Eerland, J., Aarsman, I., le Paige, U. B., Davidovich, C., Sixma, T. K. & van Ingen, H., 15 Apr 2019, In : Nature Communications. 10, 12 p., 1751.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines
Wang, X., Goodrich, K. J., Gooding, A. R., Naeem, H., Archer, S., Paucek, R. D., Youmans, D. T., Cech, T. R. & Davidovich, C., 16 Mar 2017, In : Molecular Cell. 65, 6, p. 1056-1067 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Targeting PRC2: RNA offers new opportunities
Wang, X. & Davidovich, C., 1 Jan 2017, In : Oncotarget. 8, 64, p. 107346-107347 2 p.Research output: Contribution to journal › Editorial › Other › peer-review
The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel
Wekselman, I., Zimmerman, E., Davidovich, C., Belousoff, M., Matzov, D., Krupkin, M., Rozenberg, H., Bashan, A., Friedlander, G., Kjeldgaard, J., Ingmer, H., Lindahl, L., Zengel, J. M. & Yonath, A., 1 Aug 2017, In : Structure. 25, 8, p. 1233-1241 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File