Projects per year
Personal profile
Biography
Charles is a clinical neuropsychologist, neuroscientist, and educator. He has particular interest in the clinical neuropsychology of seizure disorders, neurodegenerative disease, and neuroinflammatory conditions.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Epilepsy
- Neurocognitive disorders
- Biostatistics
- Neuropsychology
Collaborations and top research areas from the last five years
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A Phase 2, double-blind, placebo-controlled trial of sodium selenate as a disease modifying treatment for chronic drug resistant temporal lobe epilepsy (SELECT Trial)
O'Brien, T. (Primary Chief Investigator (PCI)), Vivash, L. (Chief Investigator (CI)), Churilov, L. (Chief Investigator (CI)), Kwan, P. (Chief Investigator (CI)), Carney, P. (Chief Investigator (CI)), Perucca, P. (Chief Investigator (CI)), Nicolo, J.-P. (Chief Investigator (CI)), Cook, M. J. (Chief Investigator (CI)), Gillinder, L. (Chief Investigator (CI)), Casillas-Espinosa, P. (Chief Investigator (CI)), Hovens, C. M. (Chief Investigator (CI)), Malpas, C. (Chief Investigator (CI)), Shultz, S. (Chief Investigator (CI)), Velakoulis, D. (Chief Investigator (CI)), Lawn, N. D. (Chief Investigator (CI)), Johns, H. (Associate Investigator (AI)), Wijayath, M. (Associate Investigator (AI)), Burford, J. (Associate Investigator (AI)), Wait, L. (Associate Investigator (AI)), D'Souza, W. J. (Associate Investigator (AI)) & Reutens, D. C. (Associate Investigator (AI))
1/02/23 → 31/01/28
Project: Research
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Sodium Selenate as a Disease Modifying Treatment for Progressive Supranuclear Palsy (Sodium Selenate for PSP)
O'Brien, T. (Primary Chief Investigator (PCI)), Bertram, K. (Chief Investigator (CI)), Vivash, L. (Chief Investigator (CI)), Evans, A. H. (Chief Investigator (CI)), Kimber, T. E. (Chief Investigator (CI)), O'Sullivan, J. D. (Chief Investigator (CI)), Malpas, C. (Chief Investigator (CI)), Fielding, J. (Chief Investigator (CI)), Velakoulis, D. (Chief Investigator (CI)) & Law, M. (Chief Investigator (CI))
1/06/20 → 31/05/26
Project: Research
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Evaluating the effectiveness and safety of sodium selenate as a disease modifying treatment for patients with behavioural variant Frontotemporal Dementia (bvFTD)
O'Brien, T. (Primary Chief Investigator (PCI)), Malpas, C. (Chief Investigator (CI)), Velakoulis, D. (Chief Investigator (CI)), Piguet, O. (Chief Investigator (CI)), Kalincik, T. (Chief Investigator (CI)), Walterfang, M. A. (Chief Investigator (CI)), Ahmed, R. (Chief Investigator (CI)), Bush, A. I. (Chief Investigator (CI)), Darby, D. G. (Chief Investigator (CI)) & Brodtmann, A. (Chief Investigator (CI))
Department of Health and Aged Care (Australia)
1/04/19 → 31/03/26
Project: Research
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Biomarkers to prevent disability in multiple sclerosis
Kalincik, T. (Primary Chief Investigator (PCI)), Havrdova, E. K. (Chief Investigator (CI)), Kuhle, J. (Chief Investigator (CI)), Olsson, T. (Chief Investigator (CI)), Hillert, J. (Chief Investigator (CI)), Taylor, B. V. (Chief Investigator (CI)), Malpas, C. (Chief Investigator (CI)), Kilpatrick, T. J. (Chief Investigator (CI)), Barnett, M. H. (Chief Investigator (CI)) & Buzzard, K. (Associate Investigator (AI))
1/07/19 → 30/06/22
Project: Research
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Corrigendum to “Neurofilament light and glial fibrillary acidic protein in mood and anxiety disorders: A systematic review and meta-analysis” [Brain, Behavior, and Immunity 123 (2025) 1091–1102, (S0889159124006834), (10.1016/j.bbi.2024.11.001)]
Kang, M. J. Y., Grewal, J., Eratne, D., Malpas, C., Chiu, W. H., Katisko, K., Solje, E., Santillo, A. F., Mitchell, P. B., Hopwood, M. & Velakoulis, D., Mar 2025, In: Brain, Behavior, and Immunity. 125, p. 466-470 5 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
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Cerebrospinal fluid neurofilament light predicts longitudinal diagnostic change in patients with psychiatric and neurodegenerative disorders
Kang, M. J. Y., Eratne, D., Dobson, H., Malpas, C. B., Keem, M., Lewis, C., Grewal, J., Tsoukra, V., Dang, C., Mocellin, R., Kalincik, T., Santillo, A. F., Zetterberg, H., Blennow, K., Stehmann, C., Varghese, S., Li, Q.-X., Masters, C. L., Collins, S. & Berkovic, S. F. & 6 others, , Feb 2024, In: Acta Neuropsychiatrica. 36, 1, p. 17–28 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Characterizing cognitive function in patients with autoimmune encephalitis: an Australian prospective study
Griffith, S. P., Wesselingh, R., Seery, N., Rushen, T., Kyndt, C., Long, B., Seneviratne, U., Buzzard, K., Butzkueven, H., O’Brien, T. J., Alpitsis, R., Malpas, C. B. & Monif, M., 2024, In: Journal of Neurology. 27, p. 310–324 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus) -
Cognitive and psychopathological features of neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein antibody-associated disease: A narrative review
Kazzi, C., Alpitsis, R., O'Brien, T. J., Malpas, C. B. & Monif, M., May 2024, In: Multiple Sclerosis and Related Disorders. 85, 7 p., 105596.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access5 Citations (Scopus) -
Cognitive and psychopathological outcomes in acute disseminated encephalomyelitis
Kazzi, C., Alpitsis, R., O'Brien, T. J., Malpas, C. & Monif, M., 8 May 2024, In: BMJ Neurology Open. 6, 1, 7 p., e000640.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access2 Citations (Scopus)