• 15 Innovation Walk, 75

    3800 Clayton

1985 …2021
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Research Output 1985 2019

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Article
1998
82 Citations (Scopus)

The C-C chemokine receptor CCR3 participates in stimulation of eosinophil arrest on inflammatory endothelium in shear flow

Kitayama, J., Mackay, C. R., Ponath, P. D. & Springer, T. A., 1 May 1998, In : Journal of Clinical Investigation. 101, 9, p. 2017-2024 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
193 Citations (Scopus)

The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig

Piali, L., Weber, C., LaRosa, G., Mackay, C. R., Springer, T. A., Clark-Lewis, I. & Moser, B., 1 Mar 1998, In : European Journal of Immunology. 28, 3, p. 961-972 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1112 Citations (Scopus)

The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions

Qin, S., Rottman, J. B., Myers, P., Kassam, N., Weinblatt, M., Loetscher, M., Koch, A. E., Moser, B. & Mackay, C. R., 15 Feb 1998, In : Journal of Clinical Investigation. 101, 4, p. 746-754 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1997
761 Citations (Scopus)

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

He, J., Chen, Y., Farzan, M., Choe, H., Ohagen, A., Gartner, S., Busciglio, J., Yang, X., Hofmann, W., Newman, W., Mackay, C. R., Sodroski, J. & Gabuzda, D., 13 Feb 1997, In : Nature. 385, 6617, p. 645-647 3 p.

Research output: Contribution to journalArticleResearchpeer-review

611 Citations (Scopus)

CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro

Wu, L., Paxton, W. A., Kassam, N., Ruffing, N., Rottman, J. B., Sullivan, N., Choe, H., Sodroski, J., Newman, W., Koup, R. A. & Mackay, C. R., 5 May 1997, In : Journal of Experimental Medicine. 185, 9, p. 1681-1691 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
219 Citations (Scopus)

Cellular localization of the chemokine receptor CCR5: Correlation to cellular targets of HIV-1 infection

Rottman, J. B., Ganley, K. P., Williams, K., Wu, L., Mackay, C. R. & Ringler, D. J., 1 Nov 1997, In : American Journal of Pathology. 151, 5, p. 1341-1351 11 p.

Research output: Contribution to journalArticleResearchpeer-review

417 Citations (Scopus)

Chemokine receptor usage by human eosinophils: The importance of CCR3 demonstrated using an antagonistic monoclonal antibody

Heath, H., Qin, S., Rao, P., Wu, L., LaRosa, G., Kassam, N., Ponath, P. D. & Mackay, C. R., 15 Jan 1997, In : Journal of Clinical Investigation. 99, 2, p. 178-184 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
77 Citations (Scopus)

Chemokines: What chemokine is that?

Mackay, C. R., 1 Jun 1997, In : Current Biology. 7, 6

Research output: Contribution to journalArticleResearchpeer-review

171 Citations (Scopus)

Complement C5a, TGF-β1, and MCP-1, in sequence, induce migration of monocytes into ischemic canine myocardium within the first one to five hours after reperfusion

Birdsall, H. H., Green, D. M., Trial, J. A., Youker, K. A., Burns, A. R., MacKay, C. R., LaRosa, G. J., Hawkins, H. K., Smith, C. W., Michael, L. H., Entman, M. L. & Rossen, R. D., 1 Jan 1997, In : Circulation. 95, 3, p. 684-692 9 p.

Research output: Contribution to journalArticleResearchpeer-review

369 Citations (Scopus)

Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells

Ying, S., Robinson, D. S., Meng, Q., Rottman, J., Kennedy, R., Ringler, D. J., Mackay, C. R., Daugherty, B. L., Springer, M. S., Durham, S. R., Williams, T. J. & Kay, A. B., 1 Dec 1997, In : European Journal of Immunology. 27, 12, p. 3507-3516 10 p.

Research output: Contribution to journalArticleResearchpeer-review

234 Citations (Scopus)

Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils

Gerber, B. O., Zanni, M. P., Uguccioni, M., Loetscher, M., Mackay, C. R., Pichler, W. J., Yawalkar, N., Baggiolini, M. & Moser, B., 1 Nov 1997, In : Current Biology. 7, 11, p. 836-843 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
407 Citations (Scopus)

High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines

Uguccioni, M., Mackay, C. R., Ochensberger, B., Loetscher, P., Rhis, S., LaRosa, G. J., Rao, P., Ponath, P. D., Baggiolini, M. & Dahinden, C. A., 1 Sep 1997, In : Journal of Clinical Investigation. 100, 5, p. 1137-1143 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
167 Citations (Scopus)

HIV-1 entry and macrophage inflammatory protein-1β-mediated signaling are independent functions of the chemokine receptor CCR5

Farzan, M., Choe, H., Martin, K. A., Sun, Y., Sidelko, M., Mackay, C. R., Gerard, N. P., Sodroski, J. & Gerard, C., 14 Mar 1997, In : Journal of Biological Chemistry. 272, 11, p. 6854-6857 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
497 Citations (Scopus)

Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue

Briskin, M., Winsor-Hines, D., Shyjan, A., Cochran, N., Bloom, S., Wilson, J., McEvoy, L. M., Butcher, E. C., Kassam, N., Mackay, C. R., Newman, W. & Ringler, D. J., 18 Jul 1997, In : American Journal of Pathology. 151, 1, p. 97-110 14 p.

Research output: Contribution to journalArticleResearchpeer-review

139 Citations (Scopus)

Induction of monocyte chemoattractant protein-1 in the small veins of the ischemic and reperfused canine myocardium

Kumar, A. G., Ballantyne, C. M., Michael, L. H., Kukielka, G. L., Youker, K. A., Lindsey, M. L., Hawkins, H. K., Birdsall, H. H., MacKay, C. R., LaRosa, G. J., Rossen, R. D., Smith, C. W. & Entman, M. L., 1 Jan 1997, In : Circulation. 95, 3, p. 693-700 8 p.

Research output: Contribution to journalArticleResearchpeer-review

319 Citations (Scopus)

Interaction of chemokine receptor CCR5 with its ligands: Multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding

Wu, L., LaRosa, G., Kassam, N., Gordon, C. J., Heath, H., Ruffing, N., Chen, H., Humblias, J., Samson, M., Parmentier, M., Moore, J. P. & Mackay, C. R., 20 Oct 1997, In : Journal of Experimental Medicine. 186, 8, p. 1373-1381 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
112 Citations (Scopus)

Interleukin-8 receptor B immunoreactivity in brain and neuritic plaques of Alzheimer's disease

Xia, M., Qin, S., McNamara, M., Mackay, C. & Hyman, B. T., 19 Apr 1997, In : American Journal of Pathology. 150, 4, p. 1267-1274 8 p.

Research output: Contribution to journalArticleResearchpeer-review

898 Citations (Scopus)

Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells

Sallusto, F., Mackay, C. R. & Lanzavecchia, A., 26 Sep 1997, In : Science. 277, 5334, p. 2005-2007 3 p.

Research output: Contribution to journalArticleResearchpeer-review

880 Citations (Scopus)

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

Bleul, C. C., Wu, L., Hoxie, J. A., Springer, T. A. & Mackay, C. R., 4 Mar 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 5, p. 1925-1930 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1996
197 Citations (Scopus)

Biology of chemokine and classical chemoattractant receptors: Differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells

Campbell, J. J., Qin, S., Bacon, K. B., Mackay, C. R. & Butcher, E. C., 1 Jul 1996, In : Journal of Cell Biology. 134, 1, p. 255-266 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
12 Citations (Scopus)

Characterisation of leucocytic somatic cells in bovine milk

Schmaltz, R., Bhogal, B., Wang, J., Wang, Y. Y., Mackay, C. R., Chen, S. S. & Larson, L., 1 Jan 1996, In : Research in Veterinary Science. 61, 2, p. 179-181 3 p.

Research output: Contribution to journalArticleResearchpeer-review

144 Citations (Scopus)

Chemokine expression in simian immunodeficiency virus-induced AIDS encephalitis

Sasseville, V. G., Smith, M. M., Mackay, C. R., Pauley, D. R., Mansfield, K. G., Ringler, D. J. & Lackner, A. A., 1 Nov 1996, In : American Journal of Pathology. 149, 5, p. 1459-1467 9 p.

Research output: Contribution to journalArticleResearchpeer-review

190 Citations (Scopus)

Chemokine receptors and T cell chemotaxis

Mackay, C. R., 1 Sep 1996, In : Journal of Experimental Medicine. 184, 3, p. 799-802 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
631 Citations (Scopus)

Cloning of the human eosinophil chemoattractant, eotaxin: Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils

Ponath, P. D., Qin, S., Ringler, D. J., Clark-Lewis, I., Wang, J., Kassam, N., Smith, H., Shi, X., Gonzalo, J. A., Newman, W., Gutierrez-Ramos, J. C. & Mackay, C. R., 1 Feb 1996, In : Journal of Clinical Investigation. 97, 3, p. 604-612 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
200 Citations (Scopus)

Different functions for the interleukin 8 receptors (IL-8R) of human neutrophil leukocytes: NADPH oxidase and phospholipase D are activated through IL-8R1 but not IL-8R2

Jones, S. A., Wolf, M., Qin, S., Mackay, C. R. & Baggiolini, M., 26 Jul 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 13, p. 6682-6686 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
100 Citations (Scopus)

Differential expression of homing molecules on recirculating lymphocytes from sheep gut, peripheral, and lung lymph

Abitorabi, M. A., Mackay, C. R., Jerome, E. H., Osorio, O., Butcher, E. C. & Erle, D. J., 1 May 1996, In : Journal of Immunology. 156, 9, p. 3111-3117 7 p.

Research output: Contribution to journalArticleResearchpeer-review

83 Citations (Scopus)

Discrete steps in binding and signaling of interleukin-8 with its receptor

Wu, L., Ruffing, N., Shi, X., Newman, W., Soler, D., Mackay, C. R. & Qin, S., 17 Dec 1996, In : Journal of Biological Chemistry. 271, 49, p. 31202-31209 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
150 Citations (Scopus)

Expression of monocyte chemoattractant protein-1 and interleukin-8 receptors on subsets of T cells: Correlation with transendothelial chemotactic potential

Qin, S., LaRosa, G., Campbell, J. J., Smith-Heath, H., Kassam, N., Shi, X., Zeng, L., Butcher, E. C. & Mackay, C. R., 1 Mar 1996, In : European Journal of Immunology. 26, 3, p. 640-647 8 p.

Research output: Contribution to journalArticleResearchpeer-review

523 Citations (Scopus)

Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils

Ponath, P. D., Qin, S., Post, T. W., Wang, J., Wu, L., Gerard, N. P., Newman, W., Gerard, C. & Mackay, C. R., 1 Jun 1996, In : Journal of Experimental Medicine. 183, 6, p. 2437-2448 12 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

Phenotype, and migration properties of three major subsets of tissue homing T cells in sheep

Mackay, C. R., Andrew, D. P., Briskin, M., Ringler, D. J. & Butcher, E. C., 22 Oct 1996, In : European Journal of Immunology. 26, 10, p. 2433-2439 7 p.

Research output: Contribution to journalArticleResearchpeer-review

277 Citations (Scopus)

Rapid resolution of chronic colitis in the cotton-top tamarin with an antibody to a gut-homing integrin α4β7

Hesterberg, P. E., Winsor-Hines, D., Briskin, M. J., Soler-Ferran, D., Merrill, C., Mackay, C. R., Newman, W. & Ringler, D. J., 1 Jan 1996, In : Gastroenterology. 111, 5, p. 1373-1380 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1998 Citations (Scopus)

The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

Choe, H., Farzan, M., Sun, Y., Sullivan, N., Rollins, B., Ponath, P. D., Wu, L., Mackay, C. R., LaRosa, G., Newman, W., Gerard, N., Gerard, C. & Sodroski, J., 28 Jun 1996, In : Cell. 85, 7, p. 1135-1148 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1995
35 Citations (Scopus)

Expression of CD44 molecules and CD44 ligands during human thymic fetal development: Expression of CD44 isoforms is developmentally regulated

Patel, D. D., Hale, L. P., Whichard, L. P., Radcliff, G., Mackay, C. R. & Haynes, B. F., 1 Feb 1995, In : International Immunology. 7, 2, p. 277-286 10 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Lymphocyte Migration: A new spin on lymphocyte homing

Mackay, C., 1 Jan 1995, In : Current Biology. 5, 7, p. 733-736 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1994
382 Citations (Scopus)

Expression and modulation of CD44 variant isoforms in humans

Mackay, C. R., Terpe, H. J., Stauder, R., Marston, W. L., Stark, H. & Günthert, U., 1 Jan 1994, In : Journal of Cell Biology. 124, 1-2, p. 71-82 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
67 Citations (Scopus)

Overview of the First International Workshop to Define Swine Leukocyte Cluster of Differentiation (CD) Antigens

Lunney, J. K., Walker, K., Goldman, T., Aasted, B., Bianchi, A., Binns, R., Licence, S., Bischof, R., Brandon, M., Blecha, F., Kielian, T. L., McVey, D. S., Chu, R. M., Carr, M., Howard, C., Sopp, P., Davis, W., Dvorak, P., Dominguez, J., Canals, A. & 28 others, Sanchez Vizcaino, J. M., Kim, Y. B., Laude, H., Mackay, C. R., Magnusson, U., McCullough, K., Misfeldt, M., Murtaugh, M., Molitor, T., Choi, C., Pabst, R., Parkhouse, R. M., Denham, S., Yang, H., Pescovitz, M., Pospisil, R., Tlaskalova, H., Saalmueller, A., Weiland, E., Salmon, H., Sachs, D., Arn, S., Shimizu, M., Stokes, C., Stevens, K., Valpotic, I., Zuckermann, F. & Husmann, R., 1 Jan 1994, In : Veterinary Immunology and Immunopathology. 43, 1-3, p. 193-206 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1993

Cell adhesion in the immune system

Mackay, C. R. & Imhof, B. A., 1 Jan 1993, In : Trends in Immunology. 14, 3, p. 99-102 4 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Das Vorkommen von CD44 und seinen Isoformen unter orthologischen und pathologischen Bedingungen.

Translated title of the contribution: Occurrence of CD44 and its isoforms under orthological and pathological conditionsTerpe, A., Franke, F., Stark, H., Gustmann, C., Mackay, C., Marston, W. & Günthert, U., 1 Jan 1993, In : Verhandlungen der Deutschen Gesellschaft für Pathologie. 77, p. 276-281 6 p.

Research output: Contribution to journalArticleResearchpeer-review

251 Citations (Scopus)

Homing of naive, memory and effector lymphocytes

Mackay, C. R., 1 Jan 1993, In : Current Opinion in Immunology. 5, 3, p. 423-427 5 p.

Research output: Contribution to journalArticleResearchpeer-review

177 Citations (Scopus)

Immunological memory

Mackay, C. R., 1 Jan 1993, In : Advances in Immunology. 53, p. 217-265 49 p.

Research output: Contribution to journalArticleResearchpeer-review

1992
119 Citations (Scopus)

Altered patterns of T cell migration through lymph nodes and skin following antigen challenge

Mackay, C. R., Marston, W. & Dudler, L., 1 Jan 1992, In : European Journal of Immunology. 22, 9, p. 2205-2210 6 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Expression of Human CD4 in Transgenic Mice Does Not Confer Sensitivity to Human Immunodeficiency Virus Infection

Lorès, P., Boucher, V., Mackay, C., Pla, M., Von Boehmer, H., Jami, J., Barré-Sinoussi, F. & Weill, J. C., 1 Jan 1992, In : AIDS Research and Human Retroviruses. 8, 12, p. 2063-2071 9 p.

Research output: Contribution to journalArticleResearchpeer-review

94 Citations (Scopus)

Migration pathways and immunologic memory among T lymphocytes

Mackay, C. R., 1 Dec 1992, In : Seminars in Immunology. 4, 1, p. 51-58 8 p.

Research output: Contribution to journalArticleResearchpeer-review

203 Citations (Scopus)

Tissue‐specific migration pathways by phenotypically distinct subpopulations of memory T cells

Mackay, C. R., Marston, W. L., Dudler, L., Spertini, O., Tedder, T. F. & Hein, W. R., 1 Jan 1992, In : European Journal of Immunology. 22, 4, p. 887-895 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1991
9 Citations (Scopus)

Epitopes of the T19 lymphocyte surface antigen are extensively conserved in ruminants

Hein, W. R., Dudler, L., Beya, M. F. & Mackay, C. R., 1 Jan 1991, In : Veterinary Immunology and Immunopathology. 27, 1-3, p. 173-181 9 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Expression of the "T19" and "null cell" markers on γδT cells of the sheep

Mackay, C. R., Marston, W. L., Dudler, L. & Hein, W. R., 1 Jan 1991, In : Veterinary Immunology and Immunopathology. 27, 1-3, p. 183-188 6 p.

Research output: Contribution to journalArticleResearchpeer-review

103 Citations (Scopus)

Function and evolutionary conservation of distinct epitopes on the leukocyte adhesion molecule-1 (TQ-1, Leu-8) that regulate leukocyte migration

Spertini, O., Kansas, G. S., Reimann, K. A., Mackay, C. R. & Tedder, T. F., 1 Aug 1991, In : Journal of Immunology. 147, 3, p. 942-949 8 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Marked variations in γδ T cell numbers and distribution throughout the life of sheep

Mackay, C. R. & Hein, W. R., 16 Jul 1991, In : Current topics in microbiology and immunology. 173, p. 107-111 5 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Other surface antigens identified on sheep leukocytes

Hein, W. R. & Mackay, C. R., 1 Jan 1991, In : Veterinary Immunology and Immunopathology. 27, 1-3, p. 115-118 4 p.

Research output: Contribution to journalArticleResearchpeer-review

227 Citations (Scopus)

Somatic generation of diversity in a mammalian primary lymphoid organ: The sheep ileal Peyer's patches

Reynaud, C. A., Mackay, C. R., Müller, R. G. & Weill, J. C., 8 Mar 1991, In : Cell. 64, 5, p. 995-1005 11 p.

Research output: Contribution to journalArticleResearchpeer-review