• 15 Innovation Walk, 75

    3800 Clayton

1985 …2021

Research output per year

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Research Output

1997

Interleukin-8 receptor B immunoreactivity in brain and neuritic plaques of Alzheimer's disease

Xia, M., Qin, S., McNamara, M., Mackay, C. & Hyman, B. T., 19 Apr 1997, In : American Journal of Pathology. 150, 4, p. 1267-1274 8 p.

Research output: Contribution to journalArticleResearchpeer-review

113 Citations (Scopus)

Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells

Sallusto, F., Mackay, C. R. & Lanzavecchia, A., 26 Sep 1997, In : Science. 277, 5334, p. 2005-2007 3 p.

Research output: Contribution to journalArticleResearchpeer-review

899 Citations (Scopus)

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

Bleul, C. C., Wu, L., Hoxie, J. A., Springer, T. A. & Mackay, C. R., 4 Mar 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 5, p. 1925-1930 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
886 Citations (Scopus)
1996

Biology of chemokine and classical chemoattractant receptors: Differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells

Campbell, J. J., Qin, S., Bacon, K. B., Mackay, C. R. & Butcher, E. C., 1 Jul 1996, In : Journal of Cell Biology. 134, 1, p. 255-266 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
198 Citations (Scopus)

Characterisation of leucocytic somatic cells in bovine milk

Schmaltz, R., Bhogal, B., Wang, J., Wang, Y. Y., Mackay, C. R., Chen, S. S. & Larson, L., 1 Jan 1996, In : Research in Veterinary Science. 61, 2, p. 179-181 3 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Chemokine expression in simian immunodeficiency virus-induced AIDS encephalitis

Sasseville, V. G., Smith, M. M., Mackay, C. R., Pauley, D. R., Mansfield, K. G., Ringler, D. J. & Lackner, A. A., 1 Nov 1996, In : American Journal of Pathology. 149, 5, p. 1459-1467 9 p.

Research output: Contribution to journalArticleResearchpeer-review

144 Citations (Scopus)

Chemokine receptors and T cell chemotaxis

Mackay, C. R., 1 Sep 1996, In : The Journal of Experimental Medicine. 184, 3, p. 799-802 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
190 Citations (Scopus)

Cloning of the human eosinophil chemoattractant, eotaxin: Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils

Ponath, P. D., Qin, S., Ringler, D. J., Clark-Lewis, I., Wang, J., Kassam, N., Smith, H., Shi, X., Gonzalo, J. A., Newman, W., Gutierrez-Ramos, J. C. & Mackay, C. R., 1 Feb 1996, In : Journal of Clinical Investigation. 97, 3, p. 604-612 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
631 Citations (Scopus)

Different functions for the interleukin 8 receptors (IL-8R) of human neutrophil leukocytes: NADPH oxidase and phospholipase D are activated through IL-8R1 but not IL-8R2

Jones, S. A., Wolf, M., Qin, S., Mackay, C. R. & Baggiolini, M., 26 Jul 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 13, p. 6682-6686 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
200 Citations (Scopus)

Differential expression of homing molecules on recirculating lymphocytes from sheep gut, peripheral, and lung lymph

Abitorabi, M. A., Mackay, C. R., Jerome, E. H., Osorio, O., Butcher, E. C. & Erle, D. J., 1 May 1996, In : Journal of Immunology. 156, 9, p. 3111-3117 7 p.

Research output: Contribution to journalArticleResearchpeer-review

100 Citations (Scopus)

Discrete steps in binding and signaling of interleukin-8 with its receptor

Wu, L., Ruffing, N., Shi, X., Newman, W., Soler, D., Mackay, C. R. & Qin, S., 17 Dec 1996, In : Journal of Biological Chemistry. 271, 49, p. 31202-31209 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
83 Citations (Scopus)

Expression of monocyte chemoattractant protein-1 and interleukin-8 receptors on subsets of T cells: Correlation with transendothelial chemotactic potential

Qin, S., LaRosa, G., Campbell, J. J., Smith-Heath, H., Kassam, N., Shi, X., Zeng, L., Butcher, E. C. & Mackay, C. R., 1 Mar 1996, In : European Journal of Immunology. 26, 3, p. 640-647 8 p.

Research output: Contribution to journalArticleResearchpeer-review

151 Citations (Scopus)

Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils

Ponath, P. D., Qin, S., Post, T. W., Wang, J., Wu, L., Gerard, N. P., Newman, W., Gerard, C. & Mackay, C. R., 1 Jun 1996, In : The Journal of Experimental Medicine. 183, 6, p. 2437-2448 12 p.

Research output: Contribution to journalArticleResearchpeer-review

523 Citations (Scopus)

Phenotype, and migration properties of three major subsets of tissue homing T cells in sheep

Mackay, C. R., Andrew, D. P., Briskin, M., Ringler, D. J. & Butcher, E. C., 22 Oct 1996, In : European Journal of Immunology. 26, 10, p. 2433-2439 7 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

Rapid resolution of chronic colitis in the cotton-top tamarin with an antibody to a gut-homing integrin α4β7

Hesterberg, P. E., Winsor-Hines, D., Briskin, M. J., Soler-Ferran, D., Merrill, C., Mackay, C. R., Newman, W. & Ringler, D. J., 1 Jan 1996, In : Gastroenterology. 111, 5, p. 1373-1380 8 p.

Research output: Contribution to journalArticleResearchpeer-review

281 Citations (Scopus)

The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

Choe, H., Farzan, M., Sun, Y., Sullivan, N., Rollins, B., Ponath, P. D., Wu, L., Mackay, C. R., LaRosa, G., Newman, W., Gerard, N., Gerard, C. & Sodroski, J., 28 Jun 1996, In : Cell. 85, 7, p. 1135-1148 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2005 Citations (Scopus)
1995

Expression of CD44 molecules and CD44 ligands during human thymic fetal development: Expression of CD44 isoforms is developmentally regulated

Patel, D. D., Hale, L. P., Whichard, L. P., Radcliff, G., Mackay, C. R. & Haynes, B. F., 1 Feb 1995, In : International Immunology. 7, 2, p. 277-286 10 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Lymphocyte Migration: A new spin on lymphocyte homing

Mackay, C., 1 Jan 1995, In : Current Biology. 5, 7, p. 733-736 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
15 Citations (Scopus)
1994

Expression and modulation of CD44 variant isoforms in humans

Mackay, C. R., Terpe, H. J., Stauder, R., Marston, W. L., Stark, H. & Günthert, U., 1 Jan 1994, In : Journal of Cell Biology. 124, 1-2, p. 71-82 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
383 Citations (Scopus)

Overview of the First International Workshop to Define Swine Leukocyte Cluster of Differentiation (CD) Antigens

Lunney, J. K., Walker, K., Goldman, T., Aasted, B., Bianchi, A., Binns, R., Licence, S., Bischof, R., Brandon, M., Blecha, F., Kielian, T. L., McVey, D. S., Chu, R. M., Carr, M., Howard, C., Sopp, P., Davis, W., Dvorak, P., Dominguez, J., Canals, A. & 28 others, Sanchez Vizcaino, J. M., Kim, Y. B., Laude, H., Mackay, C. R., Magnusson, U., McCullough, K., Misfeldt, M., Murtaugh, M., Molitor, T., Choi, C., Pabst, R., Parkhouse, R. M., Denham, S., Yang, H., Pescovitz, M., Pospisil, R., Tlaskalova, H., Saalmueller, A., Weiland, E., Salmon, H., Sachs, D., Arn, S., Shimizu, M., Stokes, C., Stevens, K., Valpotic, I., Zuckermann, F. & Husmann, R., 1 Jan 1994, In : Veterinary Immunology and Immunopathology. 43, 1-3, p. 193-206 14 p.

Research output: Contribution to journalArticleResearchpeer-review

67 Citations (Scopus)
1993

Cell adhesion in the immune system

Mackay, C. R. & Imhof, B. A., 1 Jan 1993, In : Trends in Immunology. 14, 3, p. 99-102 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Das Vorkommen von CD44 und seinen Isoformen unter orthologischen und pathologischen Bedingungen.

Translated title of the contribution: Occurrence of CD44 and its isoforms under orthological and pathological conditionsTerpe, A., Franke, F., Stark, H., Gustmann, C., Mackay, C., Marston, W. & Günthert, U., 1 Jan 1993, In : Verhandlungen der Deutschen Gesellschaft für Pathologie. 77, p. 276-281 6 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Homing of naive, memory and effector lymphocytes

Mackay, C. R., 1 Jan 1993, In : Current Opinion in Immunology. 5, 3, p. 423-427 5 p.

Research output: Contribution to journalArticleResearchpeer-review

252 Citations (Scopus)

Immunological memory

Mackay, C. R., 1 Jan 1993, In : Advances in Immunology. 53, p. 217-265 49 p.

Research output: Contribution to journalArticleResearchpeer-review

177 Citations (Scopus)

Lymphocyte recirculation and life span in vivo

Young, A. J., Hay, J. B. & Mckay, C. R., 1 Jan 1993, In : Current topics in microbiology and immunology. 184, p. 161-173 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

40 Citations (Scopus)
1992

Altered patterns of T cell migration through lymph nodes and skin following antigen challenge

Mackay, C. R., Marston, W. & Dudler, L., 1 Jan 1992, In : European Journal of Immunology. 22, 9, p. 2205-2210 6 p.

Research output: Contribution to journalArticleResearchpeer-review

119 Citations (Scopus)

Expression of Human CD4 in Transgenic Mice Does Not Confer Sensitivity to Human Immunodeficiency Virus Infection

Lorès, P., Boucher, V., Mackay, C., Pla, M., Von Boehmer, H., Jami, J., Barré-Sinoussi, F. & Weill, J. C., 1 Jan 1992, In : AIDS Research and Human Retroviruses. 8, 12, p. 2063-2071 9 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Migration pathways and immunologic memory among T lymphocytes

Mackay, C. R., 1 Dec 1992, In : Seminars in Immunology. 4, 1, p. 51-58 8 p.

Research output: Contribution to journalArticleResearchpeer-review

94 Citations (Scopus)

Tissue‐specific migration pathways by phenotypically distinct subpopulations of memory T cells

Mackay, C. R., Marston, W. L., Dudler, L., Spertini, O., Tedder, T. F. & Hein, W. R., 1 Jan 1992, In : European Journal of Immunology. 22, 4, p. 887-895 9 p.

Research output: Contribution to journalArticleResearchpeer-review

204 Citations (Scopus)
1991

Epitopes of the T19 lymphocyte surface antigen are extensively conserved in ruminants

Hein, W. R., Dudler, L., Beya, M. F. & Mackay, C. R., 1 Jan 1991, In : Veterinary Immunology and Immunopathology. 27, 1-3, p. 173-181 9 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Expression of the "T19" and "null cell" markers on γδT cells of the sheep

Mackay, C. R., Marston, W. L., Dudler, L. & Hein, W. R., 1 Jan 1991, In : Veterinary Immunology and Immunopathology. 27, 1-3, p. 183-188 6 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Function and evolutionary conservation of distinct epitopes on the leukocyte adhesion molecule-1 (TQ-1, Leu-8) that regulate leukocyte migration

Spertini, O., Kansas, G. S., Reimann, K. A., Mackay, C. R. & Tedder, T. F., 1 Aug 1991, In : Journal of Immunology. 147, 3, p. 942-949 8 p.

Research output: Contribution to journalArticleResearchpeer-review

103 Citations (Scopus)

Marked variations in γδ T cell numbers and distribution throughout the life of sheep

Mackay, C. R. & Hein, W. R., 16 Jul 1991, In : Current topics in microbiology and immunology. 173, p. 107-111 5 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Other surface antigens identified on sheep leukocytes

Hein, W. R. & Mackay, C. R., 1 Jan 1991, In : Veterinary Immunology and Immunopathology. 27, 1-3, p. 115-118 4 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Prominence of γδ T cells in the ruminant immune system

Hein, W. R. & Mackay, C. R., 1 Jan 1991, In : Immunology Today. 12, 1, p. 30-34 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

384 Citations (Scopus)

Skin-seeking memory T cells

Mackay, C. R., 1 Jan 1991, In : Nature. 349, 6312, p. 737-738 2 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

25 Citations (Scopus)

Somatic generation of diversity in a mammalian primary lymphoid organ: The sheep ileal Peyer's patches

Reynaud, C. A., Mackay, C. R., Müller, R. G. & Weill, J. C., 8 Mar 1991, In : Cell. 64, 5, p. 995-1005 11 p.

Research output: Contribution to journalArticleResearchpeer-review

227 Citations (Scopus)

Summary of workshop findings for leukocyte antigens of sheep

Hein, W. R., Dudler, L., Marston, W. L., Hopkins, J., Dutia, B. M., Keech, K., Brandon, M. R. & Mackay, C. R., 1 Jan 1991, In : Veterinary Immunology and Immunopathology. 27, 1-3, p. 28-30 3 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

T-cell memory: the connection between function, phenotype and migration pathways

Mackay, C. R., 1 Jan 1991, In : Immunology Today. 12, 6, p. 189-192 4 p.

Research output: Contribution to journalArticleResearchpeer-review

260 Citations (Scopus)
1990

Analysis of γδ T cells in ruminants reveals further heterogeneity in γδ T-cell features and function among species

Mackay, C. R. & Hein, W. R., 1 Jan 1990, In : Research in Immunology. 141, 6, p. 611-614 4 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Naive and memory t cells show distinct pathways of lymphocyte recirculation

Mackay, C. R., Marston, W. L. & Dudler, L., 1 Mar 1990, In : The Journal of Experimental Medicine. 171, 3, p. 801-817 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
664 Citations (Scopus)
1989

A large proportion of bovine T cells express the γδ T cell receptor and show a distinct tissue distribution and surface phenotype

Mackay, C. R. & Hein, W. R., 1 Nov 1989, In : International Immunology. 1, 5, p. 540-545 6 p.

Research output: Contribution to journalArticleResearchpeer-review

139 Citations (Scopus)

Immunology and veterinary science

Mackay, C. R. & Mackay, I. R., 1 Jan 1989, In : British Veterinary Journal. 145, 2, p. 185-190 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

5 Citations (Scopus)

Qa-1 restricted recognition of foreign antigen by a γδ T-cell hybridoma

Vidović, D., Roglić, M., McKune, K., Guerder, S., MacKay, C. & Dembić, Z., 1 Jan 1989, In : Nature. 340, 6235, p. 646-650 5 p.

Research output: Contribution to journalArticleResearchpeer-review

188 Citations (Scopus)

Surface expression of differentiation antigens on lymphocytes in the ileal and jejunal Peyer's patches of lambs

Hein, W. R., Dudler, L. & Mackay, C. R., 1 Dec 1989, In : Immunology. 68, 3, p. 365-370 6 p.

Research output: Contribution to journalArticleResearchpeer-review

66 Citations (Scopus)

γ/δ T cells express a unique surface molecule appearing late during thymic development

Mackay, C. R., Beya, MF. F. & Matzinger, P., 1 Jan 1989, In : European Journal of Immunology. 19, 8, p. 1477-1483 7 p.

Research output: Contribution to journalArticleResearchpeer-review

163 Citations (Scopus)
1988

Characterization of a 95,000 molecule on sheep leucocytes homologous to murine Pgp-1 and human CD44

Mackay, C. R., Maddox, J. F., Wijffels, G. L., Mackay, I. R. & Walker, I. D., 1 Jan 1988, In : Immunology. 65, 1, p. 93-99 7 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

Lymphocyte subsets show marked differences in their distribution between blood and the afferent and efferent lymph of peripheral lymph nodes

Mackay, C. R., Kimpton, W. G., Brandon, M. R. & Cahill, R. N. P., 1 Jun 1988, In : The Journal of Experimental Medicine. 167, 6, p. 1755-1765 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
135 Citations (Scopus)

Sheep leukocyte molecules: a review of their distribution, structure and possible function

Mackay, C., 1 Jan 1988, In : Veterinary Immunology and Immunopathology. 19, 1, p. 1-20 20 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Unusual expression of CD2 in sheep: implications for T cell interactions

Mackay, C. R., Hein, W. R., Brown, M. H. & Matzinger, P., 1 Jan 1988, In : European Journal of Immunology. 18, 11, p. 1681-1688 8 p.

Research output: Contribution to journalArticleResearchpeer-review

92 Citations (Scopus)