• 15 Innovation Walk, 75

    3800 Clayton

1985 …2021
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Research Output 1985 2019

Abstract

Effect of Dietary Fibre Intake and the Gut Microbiota in a Model of Heart Failure

Coelho Marques, F., Nelson, E. M., Chu, P. Y., Horlock, D., Fiedler, A., Ziemann, M. D., Tan, J., Kuruppu, D. M. S., Rajapakse, N., El-Osta, A., Mackay, C. R. & Kaye, D. M., 11 Nov 2016. 1 p.

Research output: Contribution to conferenceAbstract

Intergenerational Prevention Of Heart Failure Through Maternal Intake Of High Fibre

Jama, H. A., Shihata, W., Ziemann, M. D., Donner, D. G., Kiriazis, H., Du, X-J., El-Osta, A., Mackay, C. R., Kaye, D. M. & Coelho Marques, F., Feb 2019. 1 p.

Research output: Contribution to conferenceAbstract

Article
11 Citations (Scopus)

A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6

Robert, R., Juglair, L., Lim, E. X., Ang, C., Wang, C. J. H., Ebert, G., Dolezal, O. & Mackay, C. R., 5 Sep 2017, In : PLoS ONE. 12, 9, 18 p., e0184278.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
138 Citations (Scopus)

A fundamental bimodal role for neuropeptide Y1 receptor in the immune system

Wheway, J., Mackay, C. R., Newton, R., Sainsbury, A., Boey, D., Herzog, H. & Mackay-Fisson, F., 2005, In : Journal of Experimental Medicine. 202, 11, p. 1527 - 1538 12 p.

Research output: Contribution to journalArticleResearchpeer-review

502 Citations (Scopus)

A fundamental role for interleukin-21 in the generation of T follicular helper cells

Vogelzang, A., McGuire, H. N., Yu, D., Sprent, J., Mackay, C. R. & King, C., 2008, In : Immunity. 29, 1, p. 127 - 137 11 p.

Research output: Contribution to journalArticleResearchpeer-review

139 Citations (Scopus)

A large proportion of bovine T cells express the γδ T cell receptor and show a distinct tissue distribution and surface phenotype

Mackay, C. R. & Hein, W. R., 1 Nov 1989, In : International Immunology. 1, 5, p. 540-545 6 p.

Research output: Contribution to journalArticleResearchpeer-review

119 Citations (Scopus)

Altered patterns of T cell migration through lymph nodes and skin following antigen challenge

Mackay, C. R., Marston, W. & Dudler, L., 1 Jan 1992, In : European Journal of Immunology. 22, 9, p. 2205-2210 6 p.

Research output: Contribution to journalArticleResearchpeer-review

200 Citations (Scopus)

Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry

Dragic, T., Trkola, A., Lin, S. W., Nagashima, K. A., Kajumo, F., Zhao, L., Olson, W. C., Wu, L., Mackay, C. R., Allaway, G. P., Sakmar, T. P., Moore, J. P. & Maddon, P. J., 1 Jan 1998, In : Journal of Virology. 72, 1, p. 279-285 7 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

A monoclonal antibody to the p220 component of sheep LCA identifies B cells and a unique lymphocyte subset

Mackay, C. R., Maddox, J. F. & Brandon, M. R., 1 Jan 1987, In : Cellular Immunology. 110, 1, p. 46-55 10 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

An acetate-specific GPCR, FFAR2, regulates insulin secretion

Priyadarshini, M., Villa, S. R., Fuller, M., Wicksteed, B., Mackay, C. R., Alquier, T., Poitout, V., Mancebo, H., Mirmira, R. G., Gilchrist, A. & Layden, B. T., 2015, In : Molecular Endocrinology. 29, 7, p. 1055 - 1066 12 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Analysis of γδ T cells in ruminants reveals further heterogeneity in γδ T-cell features and function among species

Mackay, C. R. & Hein, W. R., 1 Jan 1990, In : Research in Immunology. 141, 6, p. 611-614 4 p.

Research output: Contribution to journalArticleResearchpeer-review

83 Citations (Scopus)

A role for gut microbiota and the metabolite-sensing receptor GPR43 in a murine model of gout

Vieira, A. T., Macia, L., Galvao, I., Martins, F. S., Canesso, M. C. C., Amaral, F. A., Garcia, C. C. O., Maslowski, K. M., De Leon, E., Shim, D. S. C., Nicoli, J. R., Harper, J. L., Teixeira, M. M. & Mackay, C. R., 2015, In : Arthritis and Rheumatology. 67, 6, p. 1646 - 1656 11 p.

Research output: Contribution to journalArticleResearchpeer-review

735 Citations (Scopus)

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome

Groom, J., Kalled, S. L., Cutler, A. H., Olson, C., Woodcock, S. A., Schneider, P., Tschopp, J., Cachero, T. G., Batten, M., Wheway, J., Mauri, D., Cavill, D., Gordon, T. P., Mackay, C. R. & Mackay, F., 1 Jan 2002, In : Journal of Clinical Investigation. 109, 1, p. 59-68 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2 Citations (Scopus)

Avenues to autoimmune arthritis triggered by diverse remote inflammatory challenges

Chevalier, N., Tan, J. K., Mason, L. J., Robert, R., McKenzie, C. I., Lim, F., Wong, C. H., Macia, L., Thorburn, A. N., Russ, B. E., Masters, S. L. & Mackay, C. R., 1 Sep 2016, In : Journal of Autoimmunity. 73, p. 120-129 10 p.

Research output: Contribution to journalArticleResearchpeer-review

257 Citations (Scopus)

BAFF and MyD88 signals promote a lupuslike disease independent of T cells

Groom, J. R., Fletcher, C. A., Walters, S. N., Gray, S. T., Watt, S. V., Sweet, M. J., Smyth, M. J., Mackay, C. R. & Mackay-Fisson, F., 2007, In : Journal of Experimental Medicine. 204, 8, p. 1959 - 1971 13 p.

Research output: Contribution to journalArticleResearchpeer-review

111 Citations (Scopus)

BAFF augments certain Th1-associated inflammatory responses

Sutherland, A. P. R., Ng, L. G., Fletcher, C. A., Shum, B. OV., Newton, R., Grey, S., Rolph, M. S., Mackay-Fisson, F. & Mackay, C. R., 2005, In : Journal of Immunology. 174, 9, p. 5537 - 5544 8 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)

BAFF-R, the major B cell-activating factor receptor, is expressed on most mature B cells and B-cell lymphoproliferative disorders

Rodig, S. J., Shahsafaei, A., Li, B., Mackay, C. R. & Dorfman, D. M., 2005, In : Human Pathology. 36, 10, p. 1113 - 1119 7 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

BAFF regulates activation of self-reactive T cells through B-cell dependent mechanisms and mediates protection in NOD mice

Marino Moreno, E., Walters, S. N., Villanueva, J. E., Richards, J. L., Mackay, C. R. & Grey, S. T., 2014, In : European Journal of Immunology. 44, 4, p. 983 - 993 11 p.

Research output: Contribution to journalArticleResearchpeer-review

333 Citations (Scopus)

B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells

Ng, L. G., Sutherland, A. P. R., Newton, R., Qian, F., Cachero, T. G., Scott, M. L., Thompson, J. S., Wheway, J., Chtanova, T., Groom, J., Sutton, I. J., Xin, C., Tangye, S. G., Kalled, S. L., Mackay-Fisson, F. & Mackay, C. R., 2004, In : Journal of Immunology. 173, 2, p. 807 - 817 11 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

B-cell cross-presentation of autologous antigen precipitates diabetes

Marino, E., Tan, B., Binge, L. C., Mackay, C. R. & Grey, S. T., 2012, In : Diabetes. 61, 11, p. 2893 - 2905 13 p.

Research output: Contribution to journalArticleResearchpeer-review

198 Citations (Scopus)

Biology of chemokine and classical chemoattractant receptors: Differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells

Campbell, J. J., Qin, S., Bacon, K. B., Mackay, C. R. & Butcher, E. C., 1 Jul 1996, In : Journal of Cell Biology. 134, 1, p. 255-266 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
10 Citations (Scopus)

C5a receptor 1 promotes autoimmunity, neutrophil dysfunction and injury in experimental anti-myeloperoxidase glomerulonephritis

Dick, J., Gan, P. Y., Ford, S. L., Odobasic, D., Alikhan, M. A., Loosen, S. H., Hall, P., Westhorpe, C. L., Li, A., Ooi, J. D., Woodruff, T. M., Mackay, C. R., Kitching, A. R., Hickey, M. J. & Holdsworth, S. R., 1 Mar 2018, In : Kidney International. 93, 3, p. 615-625 11 p.

Research output: Contribution to journalArticleResearchpeer-review

762 Citations (Scopus)

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

He, J., Chen, Y., Farzan, M., Choe, H., Ohagen, A., Gartner, S., Busciglio, J., Yang, X., Hofmann, W., Newman, W., Mackay, C. R., Sodroski, J. & Gabuzda, D., 13 Feb 1997, In : Nature. 385, 6617, p. 645-647 3 p.

Research output: Contribution to journalArticleResearchpeer-review

612 Citations (Scopus)

CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro

Wu, L., Paxton, W. A., Kassam, N., Ruffing, N., Rottman, J. B., Sullivan, N., Choe, H., Sodroski, J., Newman, W., Koup, R. A. & Mackay, C. R., 5 May 1997, In : Journal of Experimental Medicine. 185, 9, p. 1681-1691 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Cell adhesion in the immune system

Mackay, C. R. & Imhof, B. A., 1 Jan 1993, In : Trends in Immunology. 14, 3, p. 99-102 4 p.

Research output: Contribution to journalArticleResearchpeer-review

219 Citations (Scopus)

Cellular localization of the chemokine receptor CCR5: Correlation to cellular targets of HIV-1 infection

Rottman, J. B., Ganley, K. P., Williams, K., Wu, L., Mackay, C. R. & Ringler, D. J., 1 Nov 1997, In : American Journal of Pathology. 151, 5, p. 1341-1351 11 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Characterisation of leucocytic somatic cells in bovine milk

Schmaltz, R., Bhogal, B., Wang, J., Wang, Y. Y., Mackay, C. R., Chen, S. S. & Larson, L., 1 Jan 1996, In : Research in Veterinary Science. 61, 2, p. 179-181 3 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

Characterization of a 95,000 molecule on sheep leucocytes homologous to murine Pgp-1 and human CD44

Mackay, C. R., Maddox, J. F., Wijffels, G. L., Mackay, I. R. & Walker, I. D., 1 Jan 1988, In : Immunology. 65, 1, p. 93-99 7 p.

Research output: Contribution to journalArticleResearchpeer-review

146 Citations (Scopus)

Characterization of two sheep lymphocyte differentiation antigens, SBU-T1 and SBU-T6

Mackay, C. R., Maddox, J. F., Gogolin-Ewens, K. J. & Brandon, M. R., 1 Jan 1985, In : Immunology. 55, 4, p. 729-737 9 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Chemoattractant receptors and immune responses

Mackay, C. R., Lanzavecchia, A. & Sallusto, F., 1 Jan 1999, In : Immunologist. 7, 4, p. 112-118 7 p.

Research output: Contribution to journalArticleResearchpeer-review

144 Citations (Scopus)

Chemokine expression in simian immunodeficiency virus-induced AIDS encephalitis

Sasseville, V. G., Smith, M. M., Mackay, C. R., Pauley, D. R., Mansfield, K. G., Ringler, D. J. & Lackner, A. A., 1 Nov 1996, In : American Journal of Pathology. 149, 5, p. 1459-1467 9 p.

Research output: Contribution to journalArticleResearchpeer-review

190 Citations (Scopus)

Chemokine receptors and T cell chemotaxis

Mackay, C. R., 1 Sep 1996, In : Journal of Experimental Medicine. 184, 3, p. 799-802 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
417 Citations (Scopus)

Chemokine receptor usage by human eosinophils: The importance of CCR3 demonstrated using an antagonistic monoclonal antibody

Heath, H., Qin, S., Rao, P., Wu, L., LaRosa, G., Kassam, N., Ponath, P. D. & Mackay, C. R., 15 Jan 1997, In : Journal of Clinical Investigation. 99, 2, p. 178-184 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
77 Citations (Scopus)

Chemokines: What chemokine is that?

Mackay, C. R., 1 Jun 1997, In : Current Biology. 7, 6

Research output: Contribution to journalArticleResearchpeer-review

120 Citations (Scopus)

Chemotherapy induces intratumoral expression of chemokines in cutaneous melanoma, favoring T-cell infiltration and tumor control

Hong, M., Puaux, A. L., Huang, C., Loumagne, L., Tow, C., Mackay, C., Kato, M., Prévost-Blondel, A., Avril, M. F., Nardin, A. & Abastado, J. P., 15 Nov 2011, In : Cancer Research. 71, 22, p. 6997-7009 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
20 Citations (Scopus)

Chlamydia muridarum lung infection in infants alters hematopoietic cells to promote allergic airway disease in mice

Starkey, M. R., Kim, R. Y., Beckett, E. L., Schilter, H. C., Shim, D. SC., Essilfie, A-T., Nguyen, D. H., Beagley, K. W., Mattes, J., Mackay, C. R., Horvat, J. C. & Hansbro, P. M., 2012, In : PLoS ONE. 7, 8, 7 p., e42588.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
301 Citations (Scopus)

Circulating precursor CCR7(lo)PD-1(hi) CXCR5(+) CD4(+) T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure

He, J., Tsai, L. M., Leong, Y. A., Hu, X. J., Ma, C. S., Chevalier, N., Sun, X., Vandenberg, K., Rockman, S., Ding, Y., Zhu, L., Wei, W., Wang, C., Karnowski, A., Belz, G. T., Ghali, J. R., Cook, M. C., Riminton, S., Veillette, A., Schwartzberg, P. L. & 7 others, Mackay, F., Brink, R., Tangye, S. G., Vinuesa, C. G., Mackay, C. R., Li, Z. G. & Yu, D., 2013, In : Immunity. 39, p. 770 - 781 12 p.

Research output: Contribution to journalArticleResearchpeer-review

631 Citations (Scopus)

Cloning of the human eosinophil chemoattractant, eotaxin: Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils

Ponath, P. D., Qin, S., Ringler, D. J., Clark-Lewis, I., Wang, J., Kassam, N., Smith, H., Shi, X., Gonzalo, J. A., Newman, W., Gutierrez-Ramos, J. C. & Mackay, C. R., 1 Feb 1996, In : Journal of Clinical Investigation. 97, 3, p. 604-612 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
31 Citations (Scopus)

Clues to asthma pathogenesis from microarray expression studies

Rolph, M. S., Sisavanh, M., Liu, S. M. & Mackay, C. R., 2006, In : Pharmacology and Therapeutics. 109, 1-2, p. 284 - 294 11 p.

Research output: Contribution to journalArticleOther

19 Citations (Scopus)

c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses

Piovesan, D., Tempany, J., Di Pietro, A., Baas, I., Yiannis, C., O'Donnell, K., Chen, Y., Peperzak, V., Belz, G. T., Mackay, C. R., Smyth, G. K., Groom, J. R., Tarlinton, D. M. & Good-Jacobson, K. L., 18 Apr 2017, In : Cell Reports. 19, 3, p. 461-470 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
56 Citations (Scopus)

Commensal flora and the regulation of inflammatory and autoimmune responses

Kranich, J., Maslowski, K. M. & Mackay, C. R., 2011, In : Seminars in Immunology. 23, 2, p. 139 - 145 7 p.

Research output: Contribution to journalArticleResearchpeer-review

171 Citations (Scopus)

Complement C5a, TGF-β1, and MCP-1, in sequence, induce migration of monocytes into ischemic canine myocardium within the first one to five hours after reperfusion

Birdsall, H. H., Green, D. M., Trial, J. A., Youker, K. A., Burns, A. R., MacKay, C. R., LaRosa, G. J., Hawkins, H. K., Smith, C. W., Michael, L. H., Entman, M. L. & Rossen, R. D., 1 Jan 1997, In : Circulation. 95, 3, p. 684-692 9 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia

Agrawal, L., Maxwell, C. R., Peters, P. J., Clapham, P. R., Liu, S. M., Mackay, C. R. & Strayer, D. S., 2009, In : Journal of General Virology. 90, 3, p. 710 - 722 13 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)

Contribution of stromal cells to the migration, function and retention of plasma cells in human spleen: potential roles of CXCL12, IL-6 and CD54

Ellyard, J. I., Avery, D. T., Mackay, C. R. & Tangye, S. G., 2005, In : European Journal of Immunology. 35, 3, p. 699 - 708 10 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

CXCR3(+)CCR5(+) T cells and autoimmune diseases: guilty as charged?

Mackay, C. R., 2014, In : Journal of Clinical Investigation. 124, 9, p. 3682 - 3684 3 p.

Research output: Contribution to journalArticleOther

202 Citations (Scopus)

CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses

Chevalier, N., Jarrossay, D., Ho, E., Avery, D. T., Ma, C. S., Yu, D., Sallusto, F., Tangye, S. G. & Mackay, C. R., 2011, In : Journal of Immunology. 186, 10, p. 5556 - 5568 13 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Cyclophosphamide treatment induces rejection of established P815 mastocytoma by enhancing CD4 priming and intratumoral infiltration of P1E/H-2K(d) -specific CD8+ T cells

Rahir, G., Wathelet, N., Hanoteau, A., Henin, C., Oldenhove, G., Galuppo, A., Lanaya, H., Colau, D., Mackay, C. R., Van den Eynde, B. J. & Moser, M., 2014, In : International Journal of Cancer. 134, 12, p. 2841 - 2852 12 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Das Vorkommen von CD44 und seinen Isoformen unter orthologischen und pathologischen Bedingungen.

Translated title of the contribution: Occurrence of CD44 and its isoforms under orthological and pathological conditionsTerpe, A., Franke, F., Stark, H., Gustmann, C., Mackay, C., Marston, W. & Günthert, U., 1 Jan 1993, In : Verhandlungen der Deutschen Gesellschaft für Pathologie. 77, p. 276-281 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Decreased maternal serum acetate and impaired fetal thymic and regulatory T cell development in preeclampsia

Hu, M., Eviston, D., Hsu, P., Mariño, E., Chidgey, A., Santner-Nanan, B., Wong, K., Richards, J. L., Yap, Y. A., Collier, F., Quinton, A., Joung, S., Peek, M., Benzie, R., Macia, L., Wilson, D., Ponsonby, A. L., Tang, M. L. K., O’Hely, M., Daly, N. L. & 5 others, Mackay, C. R., Dahlstrom, J. E., The BIS Investigator Group, Vuillermin, P. & Nanan, R., 10 Jul 2019, In : Nature Communications. 10, 1, 13 p., 3031.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
21 Citations (Scopus)

Development of autoimmune nephritis in genetically asplenic and splenectomized BAFF transgenic mice

Fletcher, C., Groom, J., Woehl, B., Leung, H., Mackay, C. & Mackay-Fisson, F., 2011, In : Journal of Autoimmunity. 36, 2, p. 125 - 134 10 p.

Research output: Contribution to journalArticleResearchpeer-review