• 15 Innovation Walk, 75

    3800 Clayton

1985 …2021

Research output per year

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Research Output

γ/δ T cells express a unique surface molecule appearing late during thymic development

Mackay, C. R., Beya, MF. F. & Matzinger, P., 1 Jan 1989, In : European Journal of Immunology. 19, 8, p. 1477-1483 7 p.

Research output: Contribution to journalArticleResearchpeer-review

163 Citations (Scopus)

Up-regulation of CCR1 and CCR3 and induction of chemotaxis to CC chemokines by IFN-γ in human neutrophils

Bonecchi, R., Polentarutti, N., Luini, W., Borsatti, A., Bernasconi, S., Locati, M., Power, C., Proudfoot, A., Wells, T. N. C., Mackay, C., Mantovani, A. & Sozzani, S., 1 Jan 1999, In : Journal of Immunology. 162, 1, p. 474-479 6 p.

Research output: Contribution to journalArticleResearchpeer-review

167 Citations (Scopus)

Unusual expression of CD2 in sheep: implications for T cell interactions

Mackay, C. R., Hein, W. R., Brown, M. H. & Matzinger, P., 1 Jan 1988, In : European Journal of Immunology. 18, 11, p. 1681-1688 8 p.

Research output: Contribution to journalArticleResearchpeer-review

92 Citations (Scopus)

Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model

Atkinson, S. M., Nansen, A., Usher, P. A., Sondergaard, B. C., Mackay, C. R., Friedrichsen, B. N., Chang, C-C., Tang, R., Skov, S., Haase, C. G. & Hornum, L., 2015, In : Autoimmunity. 48, 7, p. 460 - 470 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma

Batten, M., Fletcher, C. A., Ng, L. G., Groom, J. R., Wheway, J., Laabi, Y., Xin, X., Schneider, P., Tschopp, J., Mackay, C. R. & Mackay-Fisson, F., 2004, In : Journal of Immunology. 172, 2, p. 812 - 822 11 p.

Research output: Contribution to journalArticleResearchpeer-review

128 Citations (Scopus)

Tissue‐specific migration pathways by phenotypically distinct subpopulations of memory T cells

Mackay, C. R., Marston, W. L., Dudler, L., Spertini, O., Tedder, T. F. & Hein, W. R., 1 Jan 1992, In : European Journal of Immunology. 22, 4, p. 887-895 9 p.

Research output: Contribution to journalArticleResearchpeer-review

204 Citations (Scopus)

Thymocyte subpopulations during early fetal development in sheep

Mackay, C. R., Maddox, J. F. & Brandon, M. R., 1 Jan 1986, In : Journal of Immunology. 136, 5, p. 1592-1599 8 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Three distinct subpopulations of sheep T lymphocytes

Mackay, C. R. & Brandon, M. R., 1 Jan 1986, In : European Journal of Immunology. 16, 1, p. 19-25 7 p.

Research output: Contribution to journalArticleResearchpeer-review

139 Citations (Scopus)

The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

Choe, H., Farzan, M., Sun, Y., Sullivan, N., Rollins, B., Ponath, P. D., Wu, L., Mackay, C. R., LaRosa, G., Newman, W., Gerard, N., Gerard, C. & Sodroski, J., 28 Jun 1996, In : Cell. 85, 7, p. 1135-1148 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2006 Citations (Scopus)

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment

Yu, D., Rao, S., Tsai, L. M., Lee, S. K., He, Y., Sutcliffe, E. L., Srivastava, M., Linterman, M., Zheng, L., Simpson, N., Ellyard, J. I., Parish, I. A., Ma, C. S., Li, Q-J., Parish, C. R., Mackay, C. R. & Vinuesa, C. G., 2009, In : Immunity. 31, 3, p. 457 - 468 12 p.

Research output: Contribution to journalArticleResearchpeer-review

689 Citations (Scopus)

The sheep analogue of leucocyte common antigen (LCA)

Maddox, J. F., Mackay, C. R. & Brandon, M. R., 1 Jan 1985, In : Immunology. 55, 2, p. 347-353 7 p.

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)

The role of short-chain fatty acids in health and disease

Tan, J., McKenzie, C., Potamitis, M., Thorburn, A. N., Mackay, C. R. & Macia, L., 2014, In : Advances in Immunology. 121, p. 91 - 119 29 p.

Research output: Contribution to journalArticleResearchpeer-review

450 Citations (Scopus)

The role of follicular helper T cell molecules and environmental influences in autoantibody production and progression to inflammatory arthritis in mice

Chevalier, N., Macia, L., Tan, J. K., Mason, L. J., Robert, R., Thorburn, A. N., Wong, C. H. Y., Tsai, L. M., Bourne, K., Brink, R., Yu, D. & Mackay, C. R., 4 Apr 2016, In : Arthritis and Rheumatology. 68, 4, p. 1026-1038 13 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

The role of chemokine receptors in primary, effector, and memory immune responses

Sallusto, F., Mackay, C. R. & Lanzavecchia, A., 27 Jun 2000, In : Annual Review of Immunology. 18, p. 593-620 28 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

898 Citations (Scopus)

The role of BAFF in B-cell maturation, T-cell activation and autoimmunity

Mackay, F. & Mackay, C. R., 1 Mar 2002, In : Trends in Immunology. 23, 3, p. 113-115 3 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

78 Citations (Scopus)

The nutrition-gut microbiome-physiology axis and allergic diseases

McKenzie, C., Tan, J., Macia, L. & Mackay, C. R., 1 Jul 2017, In : Immunological Reviews. 278, 1, p. 277-295 19 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

62 Citations (Scopus)

The metabolic sensor GPR43 receptor plays a role in the control of Klebsiella pneumoniae infection in the lung

Galvão, I., Tavares, L. P., Corrêa, R. O., Fachi, J. L., Rocha, V. M., Rungue, M., Garcia, C. C., Cassali, G., Ferreira, C. M., Martins, F. S., Oliveira, S. C., Mackay, C. R., Teixeira, M. M., Vinolo, M. A. R. & Vieira, A. T., 20 Feb 2018, In : Frontiers in Immunology. 9, 11 p., 142.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

The L3T4 antigen in mouse and the sheep equivalent are immunoglobulin-like

Classon, B. J., Tsagaratos, J., Kirszbaum, L., Maddox, J., Mackay, C. R., Brandon, M., McKenzie, I. F. C. & Walker, I. D., 1 Feb 1986, In : Immunogenetics. 23, 2, p. 129-132 4 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

Bleul, C. C., Wu, L., Hoxie, J. A., Springer, T. A. & Mackay, C. R., 4 Mar 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 5, p. 1925-1930 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
886 Citations (Scopus)

The functional plasticity of T cell subsets

Bluestone, J. A., Mackay, C. R., O'Shea, J. J. & Stockinger, B., 2009, In : Nature Reviews Immunology. 9, 11, p. 811 - 816 6 p.

Research output: Contribution to journalArticleOther

167 Citations (Scopus)

The diversity of T cells (multiple letters) [4]

Komanduri, K. V., Mccune, J. M., Von Andrian, U. H. & Mackay, C. R., 18 Jan 2001, In : New England Journal of Medicine. 344, 3, p. 231-232 2 p.

Research output: Contribution to journalLetterOtherpeer-review

The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions

Qin, S., Rottman, J. B., Myers, P., Kassam, N., Weinblatt, M., Loetscher, M., Koch, A. E., Moser, B. & Mackay, C. R., 15 Feb 1998, In : Journal of Clinical Investigation. 101, 4, p. 746-754 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1117 Citations (Scopus)

The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig

Piali, L., Weber, C., LaRosa, G., Mackay, C. R., Springer, T. A., Clark-Lewis, I. & Moser, B., 1 Mar 1998, In : European Journal of Immunology. 28, 3, p. 961-972 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
193 Citations (Scopus)

The C-C chemokine receptor CCR3 participates in stimulation of eosinophil arrest on inflammatory endothelium in shear flow

Kitayama, J., Mackay, C. R., Ponath, P. D. & Springer, T. A., 1 May 1998, In : Journal of Clinical Investigation. 101, 9, p. 2017-2024 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
83 Citations (Scopus)

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction

Bamberg, C. E., Mackay, C., Lee, H., Zahra, D., Jackson, J., Lim, Y. S., Whitfeld, P. L., Craig, S., Corsini, E., Lu, B., Gerard, C. & Gerard, N. P., 2010, In : Journal of Biological Chemistry. 285, 10, p. 7633 - 7644 12 p.

Research output: Contribution to journalArticleResearchpeer-review

158 Citations (Scopus)

The BAFF/APRIL system: Life beyond B lymphocytes

Ng, L. G., Mackay, C. R. & Mackay-Fisson, F., 2005, In : Molecular Immunology. 42, 7, p. 763 - 772 10 p.

Research output: Contribution to journalArticleResearchpeer-review

124 Citations (Scopus)

The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation

Shum, B. OV., Mackay, C. R., Gorgun, C. Z., Frost, M. J., Kumar, R. K., Hotamisligil, G. S. & Rolph, M. S., 2006, In : Journal of Clinical Investigation. 116, 8, p. 2183 - 2192 10 p.

Research output: Contribution to journalArticleResearchpeer-review

102 Citations (Scopus)

T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

Chtanova, T., Tangye, S. G., Newton, R., Frank, N., Hodge, M. R., Rolph, M. S. & Mackay, C. R., 1 Jul 2004, In : Journal of Immunology. 173, 1, p. 68-78 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
519 Citations (Scopus)

T follicular helper (TFH) cells in normal and dysregulated immune responses

King, C., Tangye, S. G. & Mackay, C. R., 2008, In : Annual Review of Immunology. 26, p. 741 - 766 26 p.

Research output: Contribution to journalArticleResearchpeer-review

475 Citations (Scopus)

T-cell memory: the connection between function, phenotype and migration pathways

Mackay, C. R., 1 Jan 1991, In : Immunology Today. 12, 6, p. 189-192 4 p.

Research output: Contribution to journalArticleResearchpeer-review

260 Citations (Scopus)

T-cell function and migration: Two sides of the same coin

Von Andrian, U. H. & Mackay, C. R., 5 Oct 2000, In : New England Journal of Medicine. 343, 14, p. 1020-1034 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

1123 Citations (Scopus)

T cell effector subsets: Extending the Th1/Th2 paradigm

Chtanova, T. & Mackay, C. R., 1 Jan 2001, Advances in Immunology. Academic Press, p. 233-266 34 p. (Advances in Immunology; vol. 78).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

44 Citations (Scopus)

Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses

Jeffrey, K. L., Camps, M., Rommel, C. & Mackay, C. R., 1 May 2007, In : Nature Reviews Drug Discovery. 6, 5, p. 391-403 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

292 Citations (Scopus)

Targeting BAFF: Immunomodulation for autoimmune diseases and lymphomas

Sutherland, A. P. R., Mackay-Fisson, F. & Mackay, C. R., 2006, In : Pharmacology and Therapeutics. 112, 3, p. 774 - 786 13 p.

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)

Surface expression of differentiation antigens on lymphocytes in the ileal and jejunal Peyer's patches of lambs

Hein, W. R., Dudler, L. & Mackay, C. R., 1 Dec 1989, In : Immunology. 68, 3, p. 365-370 6 p.

Research output: Contribution to journalArticleResearchpeer-review

66 Citations (Scopus)

Surface antigens, SBU-14 and SBU-T8, of sheep T lymphocyte subsets defined by monoclonal antibodies

Maddox, J. F., Mackay, C. R. & Brandon, M. R., 1 Jan 1985, In : Immunology. 55, 4, p. 739-748 10 p.

Research output: Contribution to journalArticleResearchpeer-review

178 Citations (Scopus)

Summary of workshop findings for leukocyte antigens of sheep

Hein, W. R., Dudler, L., Marston, W. L., Hopkins, J., Dutia, B. M., Keech, K., Brandon, M. R. & Mackay, C. R., 1 Jan 1991, In : Veterinary Immunology and Immunopathology. 27, 1-3, p. 28-30 3 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Specific expression of GPR56 by human cytotoxic lymphocytes

Peng, Y. M., van de Garde, M. D. B., Cheng, K. F., Baars, P. A., Remmerswaal, E. B. M., van Lier, R. A. W., Mackay, C. R., Lin, H. H. & Hamann, J., Oct 2011, In : Journal of leukocyte biology. 90, 4, p. 735-740 6 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Somatic generation of diversity in a mammalian primary lymphoid organ: The sheep ileal Peyer's patches

Reynaud, C. A., Mackay, C. R., Müller, R. G. & Weill, J. C., 8 Mar 1991, In : Cell. 64, 5, p. 995-1005 11 p.

Research output: Contribution to journalArticleResearchpeer-review

227 Citations (Scopus)

Skin-seeking memory T cells

Mackay, C. R., 1 Jan 1991, In : Nature. 349, 6312, p. 737-738 2 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

25 Citations (Scopus)

Short-chain fatty acids and FFAR2 as suppressors of bone resorption

Montalvany-Antonucci, C. C., Duffles, L. F., de Arruda, J. A. A., Zicker, M. C., de Oliveira, S., Macari, S., Garlet, G. P., Madeira, M. F. M., Fukada, S. Y., Andrade, I., Teixeira, M. M., Mackay, C., Vieira, A. T., Vinolo, M. A. & Silva, T. A., 1 Aug 2019, In : Bone. 125, p. 112-121 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Sheep lymphocyte antigens (OLA). II. Major histocompatibility complex class II molecules

Puri, N. K., Mackay, C. R. & Brandon, M. R., 1 Dec 1985, In : Immunology. 56, 4, p. 725-733 9 p.

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)

Sheep lymphocyte antigens (OLA). I. Major histocompatibility complex class I molecules

Gogolin-Ewens, K. J., Mackay, C. R., Mercer, W. R. & Brandon, M. R., 1 Dec 1985, In : Immunology. 56, 4, p. 717-723 7 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Sheep leukocyte molecules: a review of their distribution, structure and possible function

Mackay, C., 1 Jan 1988, In : Veterinary Immunology and Immunopathology. 19, 1, p. 1-20 20 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells

Sallusto, F., Mackay, C. R. & Lanzavecchia, A., 26 Sep 1997, In : Science. 277, 5334, p. 2005-2007 3 p.

Research output: Contribution to journalArticleResearchpeer-review

900 Citations (Scopus)

Role of the β-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia

Ghorpade, A., Xia, M. Q. I., Hyman, B. T., Persidsky, Y., Nukuna, A., Bock, P., Che, M., Limoges, J., Gendelman, H. E. & Mackay, C. R., 1 Apr 1998, In : Journal of Virology. 72, 4, p. 3351-3361 11 p.

Research output: Contribution to journalArticleResearchpeer-review

130 Citations (Scopus)

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

Maslowski, K. M., Vieira, A. T., Ng, A., Kranich, J., Sierro, F., Yu, D., Schilter, H. C., Rolph, M. S., Mackay-Fisson, F., Artis, D., Xavier, R. J., Teixeira, M. M. & Mackay, C. R., 2009, In : Nature. 461, 7268, p. 1282 - 1286 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1445 Citations (Scopus)

Regulation of dendritic cell function and T cell priming by the fatty acid-binding protein AP2

Rolph, M. S., Young, T. R., Shum, B. OV., Gorgun, C. Z., Schmitz-Peiffer, C., Ramshaw, I. A., Hotamisligil, G. S. & Mackay, C. R., 2006, In : Journal of Immunology. 177, 11, p. 7794 - 7801 8 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Reduced HIV-1 infectability of CDd4+ lymphocytes from exposed- uninfected individuals: Association with low expression of CCR5 and high production of β-chemokines

Paxton, W. A., Liu, R., Kang, S., Wu, L., Gingeras, T. R., Landau, N. R., MacKay, C. R. & Koup, R. A., 25 Apr 1998, In : Virology. 244, 1, p. 66-73 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
140 Citations (Scopus)

Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2

Lee, H., Whitfeld, P. L. & Mackay, C. R., 1 Feb 2008, In : Immunology and Cell Biology. 86, 2, p. 153-160 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

93 Citations (Scopus)