• 15 Innovation Walk, 75

    3800 Clayton

1985 …2021

Research output per year

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Research Output

Other surface antigens identified on sheep leukocytes

Hein, W. R. & Mackay, C. R., 1 Jan 1991, In : Veterinary Immunology and Immunopathology. 27, 1-3, p. 115-118 4 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Overlapping gene expression profiles in rheumatoid fibroblast-like synoviocytes induced by the proinflammatory cytokines interleukin-1? and tumor necrosis factor

Taberner, M., Scott, K. F., Weininger, L., Mackay, C. R. & Rolph, M. S., 2005, In : Inflammation Research. 54, 1, p. 10 - 16 7 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Overview of the First International Workshop to Define Swine Leukocyte Cluster of Differentiation (CD) Antigens

Lunney, J. K., Walker, K., Goldman, T., Aasted, B., Bianchi, A., Binns, R., Licence, S., Bischof, R., Brandon, M., Blecha, F., Kielian, T. L., McVey, D. S., Chu, R. M., Carr, M., Howard, C., Sopp, P., Davis, W., Dvorak, P., Dominguez, J., Canals, A. & 28 others, Sanchez Vizcaino, J. M., Kim, Y. B., Laude, H., Mackay, C. R., Magnusson, U., McCullough, K., Misfeldt, M., Murtaugh, M., Molitor, T., Choi, C., Pabst, R., Parkhouse, R. M., Denham, S., Yang, H., Pescovitz, M., Pospisil, R., Tlaskalova, H., Saalmueller, A., Weiland, E., Salmon, H., Sachs, D., Arn, S., Shimizu, M., Stokes, C., Stevens, K., Valpotic, I., Zuckermann, F. & Husmann, R., 1 Jan 1994, In : Veterinary Immunology and Immunopathology. 43, 1-3, p. 193-206 14 p.

Research output: Contribution to journalArticleResearchpeer-review

67 Citations (Scopus)

Overview of the Second International Workshop to define Swine Cluster of Differentiation (CD) antigens

Saalmüller, A., Pauly, T., Lunney, J. K., Boyd, P., Aasted, B., Sachs, D. H., Arn, S., Bianchi, A., Binns, R. M., Licence, S., Whyte, A., Blecha, F., Chen, Z., Chu, R. M., Davis, W. C., Denham, S., Yang, H., Whittall, T., Parkhouse, R. M., Dominguez, J. & 29 others, Ezquerra, A., Alonso, F., Horstick, G., Howard, C., Sopp, P., Kim, Y. B., Lipp, J., Mackay, C., Magyar, A., McCullough, K., Arriens, A., Summerfield, A., Murtaugh, M., Nielsen, J., Novikov, B., Pescovitz, M. D., Schuberth, H. J., Leibold, W., Schütt, C., Shimizu, M., Stokes, C., Haverson, K., Bailey, M., Tlaskalova, H., Trebichavsky, I., Valpotic, I., Walker, J., Lee, R. & Zuckermann, F., 30 Jan 1998, In : Veterinary Immunology and Immunopathology. 60, 3-4, p. 207-228 22 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Phenotype, and migration properties of three major subsets of tissue homing T cells in sheep

Mackay, C. R., Andrew, D. P., Briskin, M., Ringler, D. J. & Butcher, E. C., 22 Oct 1996, In : European Journal of Immunology. 26, 10, p. 2433-2439 7 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

Polymorphism in the 5' regulatory region of the B-lymphocyte activating factor gene is associated with the Ro/La autoantibody response and serum BAFF levels in primary Sjogren's syndrome

Nossent, J. C., Lester, S., Zahra, D., Mackay, C. R. & Rischmueller, M., 2008, In : Rheumatology. 47, 9, p. 1311 - 1316 6 p.

Research output: Contribution to journalArticleResearchpeer-review

46 Citations (Scopus)

Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1

Jeffrey, K. L., Brummer, T., Rolph, M. S., Liu, S. M., Callejas, N. A., Grumont, R. J., Gillieron, C., Mackay-Fisson, F., Grey, S., Camps, M., Rommel, C., Gerondakis, S. D. & Mackay, C. R., 2006, In : Nature Immunology. 7, 3, p. 274 - 283 10 p.

Research output: Contribution to journalArticleResearchpeer-review

167 Citations (Scopus)

Prominence of γδ T cells in the ruminant immune system

Hein, W. R. & Mackay, C. R., 1 Jan 1991, In : Immunology Today. 12, 1, p. 30-34 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

384 Citations (Scopus)

Protection against Nippostrongylus brasiliensis infection in mice is independent of GM-CSF

Shim, D. SC., Schilter, H. C., Knott, M. L., Almeida, R. A., Short, R. P., Mackay, C. R., Dent, L. A. & Sewell, W. A., 2012, In : Immunology and Cell Biology. 90, 5, p. 553 - 558 6 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Qa-1 restricted recognition of foreign antigen by a γδ T-cell hybridoma

Vidović, D., Roglić, M., McKune, K., Guerder, S., MacKay, C. & Dembić, Z., 1 Jan 1989, In : Nature. 340, 6235, p. 646-650 5 p.

Research output: Contribution to journalArticleResearchpeer-review

188 Citations (Scopus)

Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation

Sallusto, F., Schaerli, P., Loetscher, P., Schaniel, C., Lenig, D., Mackay, C. R., Qin, S. & Lanzavecchia, A., 1 Sep 1998, In : European Journal of Immunology. 28, 9, p. 2760-2769 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
906 Citations (Scopus)

Rapid-onset clinical and mechanistic effects of anti-C5aR treatment in the mouse collagen-induced arthritis model

Andersson, C. T., Wenander, C. S., Usher, P. A., Hebsgaard, J. B., Sondergaard, B. C., Rono, B., Mackay, C. R., Friedrichsen, B. N., Chang, C., Tang, R. & Hornum, L., 2014, In : Clinical and Experimental Immunology. 177, 1, p. 219 - 233 15 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Rapid resolution of chronic colitis in the cotton-top tamarin with an antibody to a gut-homing integrin α4β7

Hesterberg, P. E., Winsor-Hines, D., Briskin, M. J., Soler-Ferran, D., Merrill, C., Mackay, C. R., Newman, W. & Ringler, D. J., 1 Jan 1996, In : Gastroenterology. 111, 5, p. 1373-1380 8 p.

Research output: Contribution to journalArticleResearchpeer-review

281 Citations (Scopus)

Real-time interactive two-photon photoconversion of recirculating lymphocytes for discontinuous cell tracking in live adult mice

Chtanova, T., Hampton, H. R., Waterhouse, L. A., Wood, K., Tomura, M., Miwa, Y., Mackay, C. R., Brink, R. & Phan, T. G., 2014, In : Journal of Biophotonics. 7, 6, p. 425 - 433 9 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2

Lee, H., Whitfeld, P. L. & Mackay, C. R., 1 Feb 2008, In : Immunology and Cell Biology. 86, 2, p. 153-160 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

93 Citations (Scopus)

Reduced HIV-1 infectability of CDd4+ lymphocytes from exposed- uninfected individuals: Association with low expression of CCR5 and high production of β-chemokines

Paxton, W. A., Liu, R., Kang, S., Wu, L., Gingeras, T. R., Landau, N. R., MacKay, C. R. & Koup, R. A., 25 Apr 1998, In : Virology. 244, 1, p. 66-73 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
140 Citations (Scopus)

Regulation of dendritic cell function and T cell priming by the fatty acid-binding protein AP2

Rolph, M. S., Young, T. R., Shum, B. OV., Gorgun, C. Z., Schmitz-Peiffer, C., Ramshaw, I. A., Hotamisligil, G. S. & Mackay, C. R., 2006, In : Journal of Immunology. 177, 11, p. 7794 - 7801 8 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

Maslowski, K. M., Vieira, A. T., Ng, A., Kranich, J., Sierro, F., Yu, D., Schilter, H. C., Rolph, M. S., Mackay-Fisson, F., Artis, D., Xavier, R. J., Teixeira, M. M. & Mackay, C. R., 2009, In : Nature. 461, 7268, p. 1282 - 1286 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1435 Citations (Scopus)

Role of the β-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia

Ghorpade, A., Xia, M. Q. I., Hyman, B. T., Persidsky, Y., Nukuna, A., Bock, P., Che, M., Limoges, J., Gendelman, H. E. & Mackay, C. R., 1 Apr 1998, In : Journal of Virology. 72, 4, p. 3351-3361 11 p.

Research output: Contribution to journalArticleResearchpeer-review

130 Citations (Scopus)

Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells

Sallusto, F., Mackay, C. R. & Lanzavecchia, A., 26 Sep 1997, In : Science. 277, 5334, p. 2005-2007 3 p.

Research output: Contribution to journalArticleResearchpeer-review

899 Citations (Scopus)

Sheep leukocyte molecules: a review of their distribution, structure and possible function

Mackay, C., 1 Jan 1988, In : Veterinary Immunology and Immunopathology. 19, 1, p. 1-20 20 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Sheep lymphocyte antigens (OLA). I. Major histocompatibility complex class I molecules

Gogolin-Ewens, K. J., Mackay, C. R., Mercer, W. R. & Brandon, M. R., 1 Dec 1985, In : Immunology. 56, 4, p. 717-723 7 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Sheep lymphocyte antigens (OLA). II. Major histocompatibility complex class II molecules

Puri, N. K., Mackay, C. R. & Brandon, M. R., 1 Dec 1985, In : Immunology. 56, 4, p. 725-733 9 p.

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)

Short-chain fatty acids and FFAR2 as suppressors of bone resorption

Montalvany-Antonucci, C. C., Duffles, L. F., de Arruda, J. A. A., Zicker, M. C., de Oliveira, S., Macari, S., Garlet, G. P., Madeira, M. F. M., Fukada, S. Y., Andrade, I., Teixeira, M. M., Mackay, C., Vieira, A. T., Vinolo, M. A. & Silva, T. A., 1 Aug 2019, In : Bone. 125, p. 112-121 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Skin-seeking memory T cells

Mackay, C. R., 1 Jan 1991, In : Nature. 349, 6312, p. 737-738 2 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

25 Citations (Scopus)

Somatic generation of diversity in a mammalian primary lymphoid organ: The sheep ileal Peyer's patches

Reynaud, C. A., Mackay, C. R., Müller, R. G. & Weill, J. C., 8 Mar 1991, In : Cell. 64, 5, p. 995-1005 11 p.

Research output: Contribution to journalArticleResearchpeer-review

227 Citations (Scopus)

Specific expression of GPR56 by human cytotoxic lymphocytes

Peng, Y. M., van de Garde, M. D. B., Cheng, K. F., Baars, P. A., Remmerswaal, E. B. M., van Lier, R. A. W., Mackay, C. R., Lin, H. H. & Hamann, J., Oct 2011, In : Journal of leukocyte biology. 90, 4, p. 735-740 6 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Summary of workshop findings for leukocyte antigens of sheep

Hein, W. R., Dudler, L., Marston, W. L., Hopkins, J., Dutia, B. M., Keech, K., Brandon, M. R. & Mackay, C. R., 1 Jan 1991, In : Veterinary Immunology and Immunopathology. 27, 1-3, p. 28-30 3 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Surface antigens, SBU-14 and SBU-T8, of sheep T lymphocyte subsets defined by monoclonal antibodies

Maddox, J. F., Mackay, C. R. & Brandon, M. R., 1 Jan 1985, In : Immunology. 55, 4, p. 739-748 10 p.

Research output: Contribution to journalArticleResearchpeer-review

178 Citations (Scopus)

Surface expression of differentiation antigens on lymphocytes in the ileal and jejunal Peyer's patches of lambs

Hein, W. R., Dudler, L. & Mackay, C. R., 1 Dec 1989, In : Immunology. 68, 3, p. 365-370 6 p.

Research output: Contribution to journalArticleResearchpeer-review

66 Citations (Scopus)

Targeting BAFF: Immunomodulation for autoimmune diseases and lymphomas

Sutherland, A. P. R., Mackay-Fisson, F. & Mackay, C. R., 2006, In : Pharmacology and Therapeutics. 112, 3, p. 774 - 786 13 p.

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)

Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses

Jeffrey, K. L., Camps, M., Rommel, C. & Mackay, C. R., 1 May 2007, In : Nature Reviews Drug Discovery. 6, 5, p. 391-403 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

291 Citations (Scopus)

T cell effector subsets: Extending the Th1/Th2 paradigm

Chtanova, T. & Mackay, C. R., 1 Jan 2001, Advances in Immunology. Academic Press, p. 233-266 34 p. (Advances in Immunology; vol. 78).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

43 Citations (Scopus)

T-cell function and migration: Two sides of the same coin

Von Andrian, U. H. & Mackay, C. R., 5 Oct 2000, In : New England Journal of Medicine. 343, 14, p. 1020-1034 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

1123 Citations (Scopus)

T-cell memory: the connection between function, phenotype and migration pathways

Mackay, C. R., 1 Jan 1991, In : Immunology Today. 12, 6, p. 189-192 4 p.

Research output: Contribution to journalArticleResearchpeer-review

260 Citations (Scopus)

T follicular helper (TFH) cells in normal and dysregulated immune responses

King, C., Tangye, S. G. & Mackay, C. R., 2008, In : Annual Review of Immunology. 26, p. 741 - 766 26 p.

Research output: Contribution to journalArticleResearchpeer-review

475 Citations (Scopus)

T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

Chtanova, T., Tangye, S. G., Newton, R., Frank, N., Hodge, M. R., Rolph, M. S. & Mackay, C. R., 1 Jul 2004, In : Journal of Immunology. 173, 1, p. 68-78 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
518 Citations (Scopus)

The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation

Shum, B. OV., Mackay, C. R., Gorgun, C. Z., Frost, M. J., Kumar, R. K., Hotamisligil, G. S. & Rolph, M. S., 2006, In : Journal of Clinical Investigation. 116, 8, p. 2183 - 2192 10 p.

Research output: Contribution to journalArticleResearchpeer-review

102 Citations (Scopus)

The BAFF/APRIL system: Life beyond B lymphocytes

Ng, L. G., Mackay, C. R. & Mackay-Fisson, F., 2005, In : Molecular Immunology. 42, 7, p. 763 - 772 10 p.

Research output: Contribution to journalArticleResearchpeer-review

124 Citations (Scopus)

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction

Bamberg, C. E., Mackay, C., Lee, H., Zahra, D., Jackson, J., Lim, Y. S., Whitfeld, P. L., Craig, S., Corsini, E., Lu, B., Gerard, C. & Gerard, N. P., 2010, In : Journal of Biological Chemistry. 285, 10, p. 7633 - 7644 12 p.

Research output: Contribution to journalArticleResearchpeer-review

158 Citations (Scopus)

The C-C chemokine receptor CCR3 participates in stimulation of eosinophil arrest on inflammatory endothelium in shear flow

Kitayama, J., Mackay, C. R., Ponath, P. D. & Springer, T. A., 1 May 1998, In : Journal of Clinical Investigation. 101, 9, p. 2017-2024 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
83 Citations (Scopus)

The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig

Piali, L., Weber, C., LaRosa, G., Mackay, C. R., Springer, T. A., Clark-Lewis, I. & Moser, B., 1 Mar 1998, In : European Journal of Immunology. 28, 3, p. 961-972 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
193 Citations (Scopus)

The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions

Qin, S., Rottman, J. B., Myers, P., Kassam, N., Weinblatt, M., Loetscher, M., Koch, A. E., Moser, B. & Mackay, C. R., 15 Feb 1998, In : Journal of Clinical Investigation. 101, 4, p. 746-754 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1116 Citations (Scopus)

The diversity of T cells (multiple letters) [4]

Komanduri, K. V., Mccune, J. M., Von Andrian, U. H. & Mackay, C. R., 18 Jan 2001, In : New England Journal of Medicine. 344, 3, p. 231-232 2 p.

Research output: Contribution to journalLetterOtherpeer-review

The functional plasticity of T cell subsets

Bluestone, J. A., Mackay, C. R., O'Shea, J. J. & Stockinger, B., 2009, In : Nature Reviews Immunology. 9, 11, p. 811 - 816 6 p.

Research output: Contribution to journalArticleOther

167 Citations (Scopus)

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

Bleul, C. C., Wu, L., Hoxie, J. A., Springer, T. A. & Mackay, C. R., 4 Mar 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 5, p. 1925-1930 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
886 Citations (Scopus)

The L3T4 antigen in mouse and the sheep equivalent are immunoglobulin-like

Classon, B. J., Tsagaratos, J., Kirszbaum, L., Maddox, J., Mackay, C. R., Brandon, M., McKenzie, I. F. C. & Walker, I. D., 1 Feb 1986, In : Immunogenetics. 23, 2, p. 129-132 4 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

The metabolic sensor GPR43 receptor plays a role in the control of Klebsiella pneumoniae infection in the lung

Galvão, I., Tavares, L. P., Corrêa, R. O., Fachi, J. L., Rocha, V. M., Rungue, M., Garcia, C. C., Cassali, G., Ferreira, C. M., Martins, F. S., Oliveira, S. C., Mackay, C. R., Teixeira, M. M., Vinolo, M. A. R. & Vieira, A. T., 20 Feb 2018, In : Frontiers in Immunology. 9, 11 p., 142.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

The nutrition-gut microbiome-physiology axis and allergic diseases

McKenzie, C., Tan, J., Macia, L. & Mackay, C. R., 1 Jul 2017, In : Immunological Reviews. 278, 1, p. 277-295 19 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

62 Citations (Scopus)

The role of BAFF in B-cell maturation, T-cell activation and autoimmunity

Mackay, F. & Mackay, C. R., 1 Mar 2002, In : Trends in Immunology. 23, 3, p. 113-115 3 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

78 Citations (Scopus)