Projects per year
Personal profile
Biography
Position
Post-doctoral Fellow
Faculty of Pharmacy and Pharmaceutical Sciences
Drug Discovery Biology
Monash Institute of Pharmaceutical Sciences
Research area keywords
- GPCRs
- Allostery
- muscarinic receptor
- Neurocognitive Processes
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
Discovering novel allosteric probes of muscarinic acetylcholine receptors
Valant, C., Scammells, P. & Christopoulos, A.
10/06/19 → 9/06/22
Project: Research
Allosteric modulators of muscarinic acetylcholine receptors
Christopoulos, A. & Valant, C.
16/06/17 → 30/06/18
Project: Research
Understanding novel drug binding pockets at G protein-coupled receptors
National Health & Medical Research Council (NHMRC)
1/01/15 → 31/12/17
Project: Research
Understanding endogenous allosteric modulators of G protein-coupled receptors
Australian Research Council (ARC)
1/09/14 → 31/08/18
Project: Research
Research Output
Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse Colon
DiCello, J. J., Carbone, S. E., Saito, A., Rajasekhar, P., Ceredig, R. A., Pham, V., Valant, C., Christopoulos, A., Veldhuis, N. A., Canals, M., Massotte, D. & Poole, D. P., Mar 2020, In : Cellular and Molecular Gastroenterology and Hepatology. 9, 3, p. 465-483 19 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
1
Citation
(Scopus)
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity
Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs
Hollingsworth, S. A., Kelly, B., Valant, C., Michaelis, J. A., Mastromihalis, O., Thompson, G., Venkatakrishnan, A. J., Hertig, S., Scammells, P. J., Sexton, P. M., Felder, C. C., Christopoulos, A. & Dror, R. O., 1 Dec 2019, In : Nature Communications. 10, 1, p. 1-9 9 p., 3289.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
5
Citations
(Scopus)
Crystal structure of the M5 muscarinic acetylcholine receptor
Vuckovic, Z., Gentry, P. R., Berizzi, A. E., Hirata, K., Varghese, S., Thompson, G., van der Westhuizen, E. T., Burger, W. A. C., Rahmani, R., Valant, C., Langmead, C. J., Lindsley, C. W., Baell, J. B., Tobin, A. B., Sexton, P. M., Christopoulos, A. & Thal, D. M., 17 Dec 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 51, p. 26001-26007 7 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
1
Citation
(Scopus)
Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor
Desai, A. J., Mechin, I., Nagarajan, K., Valant, C., Wootten, D., Lam, P. C. H., Orry, A., Abagyan, R., Nair, A., Sexton, P. M., Christopoulos, A. & Miller, L. J., 1 Mar 2019, In : Molecular Pharmacology. 95, 3, p. 245-259 15 p.Research output: Contribution to journal › Article › Research › peer-review
Prizes
Citation Award 2015
Valant, Celine (Recipient), 30 Jun 2015
Prize: Prize (including medals and awards)
Denis Wade Johnson & Johnson New Investigator Award 2012
Valant, Celine (Recipient), Dec 2012
Prize: Prize (including medals and awards)
Outstanding New Investigator Award 2012
Valant, Celine (Recipient), Dec 2012
Prize: Prize (including medals and awards)
Activities
ASCEPT 2018
Celine Valant (Invited speaker)
26 Nov 2018 → 30 Nov 2018
Activity: Participating in or organising an event types › Contribution to conference
British Journal of Pharmacology (Journal)
Celine Valant (Peer reviewer)
9 Apr 2018 → 14 Sep 2018
Activity: Publication peer-review and editorial work types › Peer review responsibility
ACS Chemical Biology (Journal)
Celine Valant (Peer reviewer)
5 Apr 2018
Activity: Publication peer-review and editorial work types › Peer review responsibility
MP-GPCR 2018
Celine Valant (Organiser)
2 Dec 2018 → 4 Dec 2018
Activity: Participating in or organising an event types › Contribution to conference
Introduction to advanced receptor pharmacology
Celine Valant (Organiser)
14 Oct 2018 → 19 Oct 2018
Activity: Participating in or organising an event types › Contribution to workshop, seminar, course