Projects per year
Personal profile
Biography
Position
Post-doctoral Fellow
Faculty of Pharmacy and Pharmaceutical Sciences
Drug Discovery Biology
Monash Institute of Pharmaceutical Sciences
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- GPCRs
- Allostery
- muscarinic receptor
- Neurocognitive Processes
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Harnessing Endogenous Opioids to Treat Gut Motility Disorders and Pain
Poole, D. (Primary Chief Investigator (PCI)), Valant, C. (Chief Investigator (CI)), Carbone, S. (Chief Investigator (CI)), Mobbs, J. (Chief Investigator (CI)), Thal, D. (Associate Investigator (AI)), Scammells, P. (Associate Investigator (AI)), King, S. K. (Associate Investigator (AI)), Imlach, W. (Associate Investigator (AI)), Hamilton, J. A. (Associate Investigator (AI)) & Veldhuis, N. (Associate Investigator (AI))
1/01/23 → 31/12/26
Project: Research
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Modulation of the M4 muscarinic receptor for the treatment of schizophrenia
Valant, C. (Primary Chief Investigator (PCI)), Capuano, B. (Chief Investigator (CI)), Choy, C. (Chief Investigator (CI)), Thal, D. (Associate Investigator (AI)), Miao, Y. (Associate Investigator (AI)), Christopoulos, A. (Associate Investigator (AI)), Felder, C. (Associate Investigator (AI)) & Pantellis, C. (Associate Investigator (AI))
1/01/23 → 31/12/26
Project: Research
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NAMs of Gq-coupled muscarinic acetylcholine receptors
Valant, C. & Christopoulos, A.
Department of Defence (Australia)
20/09/21 → 28/02/23
Project: Research
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Discovering novel allosteric probes of muscarinic acetylcholine receptors
Valant, C. (Primary Chief Investigator (PCI)), Scammells, P. (Chief Investigator (CI)) & Christopoulos, A. (Chief Investigator (CI))
3/06/19 → 31/12/22
Project: Research
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Allosteric modulators of muscarinic acetylcholine receptors
Christopoulos, A. & Valant, C.
16/06/17 → 30/06/18
Project: Research
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Brain region-specific alterations in gene expression trajectories in the offspring born from influenza A virus infected mice
Liong, S., Choy, K. H. C., De Luca, S. N., Liong, F., Coward-Smith, M., Oseghale, O., Miles, M. A., Vlahos, R., Valant, C., Nithianantharajah, J., Pantelis, C., Christopoulos, A. & Selemidis, S., Aug 2024, In: Brain, Behavior, and Immunity. 120, p. 488-498 11 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Discovery of 2-Methyl-5-(1H-pyrazol-4-yl)pyridines and Related Heterocycles as Promising M4 mAChR Positive Allosteric Modulators for the Treatment of Neurocognitive Disorders
Liu, B., Thompson, G., Jörg, M., Barnes, N., Thal, D. M., Christopoulos, A., Capuano, B., Valant, C. & Scammells, P. J., 18 Jul 2024, In: Journal of Medicinal Chemistry. 67, 15, p. 13286–13304 19 p.Research output: Contribution to journal › Article › Research › peer-review
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Importance of receptor expression in the classification of novel ligands at the M2 muscarinic acetylcholine receptor
Jiang, Y., Yeasmin, M., Gondin, A. B., Christopoulos, A., Valant, C., Burger, W. A. C. & Thal, D. M., Jul 2024, In: British Journal of Pharmacology. 181, 14, p. 2338-2350 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access8 Citations (Scopus) -
Ligand-directed biased agonism at human histamine H3 receptor isoforms across Gαi/o- and β-arrestin2-mediated pathways
Rahman, S. N., Imhaouran, F., Leurs, R., Christopoulos, A., Valant, C. & Langmead, C. J., Oct 2024, In: Biochemical Pharmacology. 228, 24 p., 115988.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits
Nguyen, H. T. M., van der Westhuizen, E. T., Langmead, C. J., Tobin, A. B., Sexton, P. M., Christopoulos, A. & Valant, C., Jul 2024, In: British Journal of Pharmacology. 181, 14, p. 2114-2142 29 p.Research output: Contribution to journal › Review Article › Research › peer-review
12 Citations (Scopus)
Prizes
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Denis Wade Johnson & Johnson New Investigator Award 2012
Valant, Celine (Recipient), Dec 2012
Prize: Prize (including medals and awards)
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Outstanding New Investigator Award 2012
Valant, C. (Recipient), Dec 2012
Prize: Prize (including medals and awards)
Activities
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ACS Chemical Biology (Journal)
Celine Valant (Peer reviewer)
5 Apr 2018Activity: Publication peer-review and editorial work types › Peer review responsibility
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Trends in Pharmacological Sciences (Journal)
Celine Valant (Peer reviewer)
29 Mar 2018Activity: Publication peer-review and editorial work types › Peer review responsibility
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Introduction to advanced receptor pharmacology
Celine Valant (Organiser)
14 Oct 2018 → 19 Oct 2018Activity: Participating in or organising an event types › Contribution to workshop, seminar, course
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ASCEPT 2018
Celine Valant (Invited speaker)
26 Nov 2018 → 30 Nov 2018Activity: Participating in or organising an event types › Contribution to conference
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British Journal of Pharmacology (Journal)
Celine Valant (Peer reviewer)
9 Apr 2018 → 14 Sept 2018Activity: Publication peer-review and editorial work types › Peer review responsibility