Projects per year
Personal profile
Biography
Position
Post-doctoral Fellow
Faculty of Pharmacy and Pharmaceutical Sciences
Drug Discovery Biology
Monash Institute of Pharmaceutical Sciences
Research area keywords
- GPCRs
- Allostery
- muscarinic receptor
- Neurocognitive Processes
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2014 2022
Discovering novel allosteric probes of muscarinic acetylcholine receptors
Valant, C., Scammells, P. & Christopoulos, A.
10/06/19 → 9/06/22
Project: Research
Allosteric modulators of muscarinic acetylcholine receptors
Christopoulos, A. & Valant, C.
16/06/17 → 30/06/18
Project: Research
Understanding novel drug binding pockets at G protein-coupled receptors
National Health & Medical Research Council (NHMRC)
1/01/15 → 31/12/17
Project: Research
Understanding endogenous allosteric modulators of G protein-coupled receptors
Australian Research Council (ARC)
1/09/14 → 31/08/18
Project: Research
Research Output 2007 2019
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity
Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.Research output: Contribution to journal › Article › Research › peer-review
Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor
Desai, A. J., Mechin, I., Nagarajan, K., Valant, C., Wootten, D., Lam, P. C. H., Orry, A., Abagyan, R., Nair, A., Sexton, P. M., Christopoulos, A. & Miller, L. J., 1 Mar 2019, In : Molecular Pharmacology. 95, 3, p. 245-259 15 p.Research output: Contribution to journal › Article › Research › peer-review
Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors
Van Der Westhuizen, E. T., Spathis, A., Khajehali, E., Jorg, M., Mistry, S. N., Capuano, B., Tobin, A. B., Sexton, P. M., Scammells, P. J., Valant, C. & Christopoulos, A., 1 May 2018, In : Molecular Pharmacology. 94, 1, p. 770-783 14 p.Research output: Contribution to journal › Article › Research › peer-review
A Structure-Activity Relationship Study of Bitopic N 6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists
Aurelio, L., Baltos, J. A., Ford, L., Nguyen, A. T. N., Jörg, M., Devine, S. M., Valant, C., White, P. J., Christopoulos, A., May, L. T. & Scammells, P. J., 8 Mar 2018, In : Journal of Medicinal Chemistry. 61, 5, p. 2087-2103 17 p.Research output: Contribution to journal › Article › Research › peer-review
Probing the binding site of novel selective positive allosteric modulators at the M1 muscarinic acetylcholine receptor
Khajehali, E., Valant, C., Jörg, M., Tobin, A. B., Conn, P. J., Lindsley, C. W., Sexton, P. M., Scammells, P. J. & Christopoulos, A., 1 Aug 2018, In : Biochemical Pharmacology. 154, p. 243-254 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
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Prizes
Denis Wade Johnson & Johnson New Investigator Award 2012
Celine Valant (Recipient), Dec 2012
Prize: Prize (including medals and awards)
Outstanding New Investigator Award 2012
Celine Valant (Recipient), Dec 2012
Prize: Prize (including medals and awards)
Activities 2007 2018
British Journal of Pharmacology (Journal)
Celine Valant (Peer reviewer)9 Apr 2018 → 14 Sep 2018
Activity: Publication peer-review and editorial work types › Peer review responsibility
MP-GPCR 2018
Celine Valant (Organiser)2 Dec 2018 → 4 Dec 2018
Activity: Participating in or organising an event types › Contribution to conference
ASCEPT 2018
Celine Valant (Invited speaker)26 Nov 2018 → 30 Nov 2018
Activity: Participating in or organising an event types › Contribution to conference
ACS Chemical Biology (Journal)
Celine Valant (Peer reviewer)5 Apr 2018
Activity: Publication peer-review and editorial work types › Peer review responsibility
MP-GPCR 2018
Celine Valant (Invited speaker)2 Dec 2018 → 4 Dec 2018
Activity: Participating in or organising an event types › Contribution to conference