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Personal profile

Biography

Position

Post-doctoral Fellow
Faculty of Pharmacy and Pharmaceutical Sciences

Drug Discovery Biology
Monash Institute of Pharmaceutical Sciences

Research area keywords

  • GPCRs
  • Allostery
  • muscarinic receptor
  • Neurocognitive Processes

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2022

Research Output 2007 2019

  • 43 Article
  • 2 Chapter (Book)
  • 1 Comment / Debate
  • 1 Review Article

6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity

Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs

Hollingsworth, S. A., Kelly, B., Valant, C., Michaelis, J. A., Mastromihalis, O., Thompson, G., Venkatakrishnan, A. J., Hertig, S., Scammells, P. J., Sexton, P. M., Felder, C. C., Christopoulos, A. & Dror, R. O., 1 Dec 2019, In : Nature Communications. 10, 1, p. 1-9 9 p., 3289.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor

Desai, A. J., Mechin, I., Nagarajan, K., Valant, C., Wootten, D., Lam, P. C. H., Orry, A., Abagyan, R., Nair, A., Sexton, P. M., Christopoulos, A. & Miller, L. J., 1 Mar 2019, In : Molecular Pharmacology. 95, 3, p. 245-259 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Mu and Delta Opioid Receptors are Co-expressed and Functionally Interact in the Enteric Nervous System of the Mouse Colon

Di Cello, J., Carbone, S., Saito, A., Rajasekhar, P., Ceredig, R. A., Pham, V., Valant, C., Christopoulos, A., Veldhuis, N. A., Canals, M., Massotte, D. & Poole, D. P., 20 Nov 2019, (Accepted/In press) In : Cellular and Molecular Gastroenterology and Hepatology. 47 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Prizes

Citation Award 2015

Celine Valant (Recipient), 30 Jun 2015

Prize: Prize (including medals and awards)

Denis Wade Johnson & Johnson New Investigator Award 2012

Celine Valant (Recipient), Dec 2012

Prize: Prize (including medals and awards)

Outstanding New Investigator Award 2012

Celine Valant (Recipient), Dec 2012

Prize: Prize (including medals and awards)

Activities 2007 2018

  • 14 Peer review responsibility
  • 13 Contribution to conference
  • 1 Contribution to workshop, seminar, course
  • 1 Submissions to industry or govt committees, commissions and inquiries

MP-GPCR 2018

Celine Valant (Organiser)
2 Dec 20184 Dec 2018

Activity: Participating in or organising an event typesContribution to conference

ACS Chemical Biology (Journal)

Celine Valant (Peer reviewer)
5 Apr 2018

Activity: Publication peer-review and editorial work typesPeer review responsibility

Trends in Pharmacological Sciences (Journal)

Celine Valant (Peer reviewer)
29 Mar 2018

Activity: Publication peer-review and editorial work typesPeer review responsibility

MP-GPCR 2018

Celine Valant (Invited speaker)
2 Dec 20184 Dec 2018

Activity: Participating in or organising an event typesContribution to conference

Introduction to advanced receptor pharmacology

Celine Valant (Organiser)
14 Oct 201819 Oct 2018

Activity: Participating in or organising an event typesContribution to workshop, seminar, course