20072020

Research output per year

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Personal profile

Biography

Position

Post-doctoral Fellow
Faculty of Pharmacy and Pharmaceutical Sciences

Drug Discovery Biology
Monash Institute of Pharmaceutical Sciences

Research area keywords

  • GPCRs
  • Allostery
  • muscarinic receptor
  • Neurocognitive Processes

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects

Research Output

  • 44 Article
  • 2 Chapter (Book)
  • 1 Comment / Debate
  • 1 Review Article

Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse Colon

DiCello, J. J., Carbone, S. E., Saito, A., Rajasekhar, P., Ceredig, R. A., Pham, V., Valant, C., Christopoulos, A., Veldhuis, N. A., Canals, M., Massotte, D. & Poole, D. P., Mar 2020, In : Cellular and Molecular Gastroenterology and Hepatology. 9, 3, p. 465-483 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity

Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs

Hollingsworth, S. A., Kelly, B., Valant, C., Michaelis, J. A., Mastromihalis, O., Thompson, G., Venkatakrishnan, A. J., Hertig, S., Scammells, P. J., Sexton, P. M., Felder, C. C., Christopoulos, A. & Dror, R. O., 1 Dec 2019, In : Nature Communications. 10, 1, p. 1-9 9 p., 3289.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

Crystal structure of the M5 muscarinic acetylcholine receptor

Vuckovic, Z., Gentry, P. R., Berizzi, A. E., Hirata, K., Varghese, S., Thompson, G., van der Westhuizen, E. T., Burger, W. A. C., Rahmani, R., Valant, C., Langmead, C. J., Lindsley, C. W., Baell, J. B., Tobin, A. B., Sexton, P. M., Christopoulos, A. & Thal, D. M., 17 Dec 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 51, p. 26001-26007 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor

Desai, A. J., Mechin, I., Nagarajan, K., Valant, C., Wootten, D., Lam, P. C. H., Orry, A., Abagyan, R., Nair, A., Sexton, P. M., Christopoulos, A. & Miller, L. J., 1 Mar 2019, In : Molecular Pharmacology. 95, 3, p. 245-259 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Prizes

Citation Award 2015

Valant, Celine (Recipient), 30 Jun 2015

Prize: Prize (including medals and awards)

Denis Wade Johnson & Johnson New Investigator Award 2012

Valant, Celine (Recipient), Dec 2012

Prize: Prize (including medals and awards)

Outstanding New Investigator Award 2012

Valant, Celine (Recipient), Dec 2012

Prize: Prize (including medals and awards)

Activities

  • 14 Peer review responsibility
  • 13 Contribution to conference
  • 1 Contribution to workshop, seminar, course
  • 1 Submissions to industry or govt committees, commissions and inquiries

ASCEPT 2018

Celine Valant (Invited speaker)

26 Nov 201830 Nov 2018

Activity: Participating in or organising an event typesContribution to conference

British Journal of Pharmacology (Journal)

Celine Valant (Peer reviewer)

9 Apr 201814 Sep 2018

Activity: Publication peer-review and editorial work typesPeer review responsibility

ACS Chemical Biology (Journal)

Celine Valant (Peer reviewer)

5 Apr 2018

Activity: Publication peer-review and editorial work typesPeer review responsibility

MP-GPCR 2018

Celine Valant (Organiser)

2 Dec 20184 Dec 2018

Activity: Participating in or organising an event typesContribution to conference

Introduction to advanced receptor pharmacology

Celine Valant (Organiser)

14 Oct 201819 Oct 2018

Activity: Participating in or organising an event typesContribution to workshop, seminar, course