Projects per year
Personal profile
Biography
Position
Post-doctoral Fellow
Faculty of Pharmacy and Pharmaceutical Sciences
Drug Discovery Biology
Monash Institute of Pharmaceutical Sciences
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- GPCRs
- Allostery
- muscarinic receptor
- Neurocognitive Processes
Network
-
Modulation of the M4 muscarinic receptor for the treatment of schizophrenia
Valant, C., Capuano, B., Choy, C., Thal, D., Miao, Y., Christopoulos, A., Felder, C. & Pantellis, C.
1/01/23 → 31/12/26
Project: Research
-
Harnessing Endogenous Opioids to Treat Gut Motility Disorders and Pain
Poole, D., Valant, C., Carbone, S., Mobbs, J., Thal, D., Scammells, P., King, S. K., Imlach, W., Hamilton, J. A. & Veldhuis, N.
1/01/23 → 31/12/26
Project: Research
-
NAMs of Gq-coupled muscarinic acetylcholine receptors
Valant, C. & Christopoulos, A.
Department of Defence (Australia)
20/09/21 → 28/02/23
Project: Research
-
Discovering novel allosteric probes of muscarinic acetylcholine receptors
Valant, C., Scammells, P. & Christopoulos, A.
3/06/19 → 31/12/22
Project: Research
-
Allosteric modulators of muscarinic acetylcholine receptors
Christopoulos, A. & Valant, C.
16/06/17 → 30/06/18
Project: Research
-
Author Correction: Structural basis of efficacy-driven ligand selectivity at GPCRs (Nature Chemical Biology, (2023), 10.1038/s41589-022-01247-5)
Powers, A. S., Pham, V., Burger, W. A. C., Thompson, G., Laloudakis, Y., Barnes, N. W., Sexton, P. M., Paul, S. M., Christopoulos, A., Thal, D. M., Felder, C. C., Valant, C. & Dror, R. O., Apr 2023, In: Nature Chemical Biology. 19, 4, p. 529-529 1 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access -
Biased Profile of Xanomeline at the Recombinant Human M4Muscarinic Acetylcholine Receptor
McDonald, J. K., Van Der Westhuizen, E. T., Pham, V., Thompson, G., Felder, C. C., Paul, S. M., Thal, D. M., Christopoulos, A. & Valant, C., 20 Apr 2022, In: ACS Chemical Neuroscience. 13, 8, p. 1206-1218 13 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Importance of receptor expression in the classification of novel ligands at the M2 muscarinic acetylcholine receptor
Jiang, Y., Yeasmin, M., Gondin, A. B., Christopoulos, A., Valant, C., Burger, W. A. C. & Thal, D. M., 2022, (Accepted/In press) In: British Journal of Pharmacology.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Investigating Drivers for M1 Muscarinic Acetylcholine Receptor-Mediated Adverse Events by M1 Positive Allosteric Modulators
Nguyen, H. T. M., van der Westhuizen, E. T., Khajehali, E., Valant, C. & Christopoulos, A., 1 May 2022, In: The FASEB Journal. 36, S1, 1 p.Research output: Contribution to journal › Article › Other › peer-review
Open Access -
Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits
Nguyen, H. T. M., van der Westhuizen, E. T., Langmead, C. J., Tobin, A. B., Sexton, P. M., Christopoulos, A. & Valant, C., 10 Nov 2022, (Accepted/In press) In: British Journal of Pharmacology. 29 p.Research output: Contribution to journal › Review Article › Research › peer-review
1 Citation (Scopus)
Prizes
-
Citation Award 2015
Valant, Celine (Recipient), 30 Jun 2015
Prize: Prize (including medals and awards)
-
Denis Wade Johnson & Johnson New Investigator Award 2012
Valant, Celine (Recipient), Dec 2012
Prize: Prize (including medals and awards)
-
Outstanding New Investigator Award 2012
Valant, Celine (Recipient), Dec 2012
Prize: Prize (including medals and awards)
Activities
-
MP-GPCR 2018
Celine Valant (Invited speaker)
2 Dec 2018 → 4 Dec 2018Activity: Participating in or organising an event types › Contribution to conference
-
Introduction to advanced receptor pharmacology
Celine Valant (Organiser)
14 Oct 2018 → 19 Oct 2018Activity: Participating in or organising an event types › Contribution to workshop, seminar, course
-
British Journal of Pharmacology (Journal)
Celine Valant (Peer reviewer)
9 Apr 2018 → 14 Sep 2018Activity: Publication peer-review and editorial work types › Peer review responsibility
-
MP-GPCR 2018
Celine Valant (Organiser)
2 Dec 2018 → 4 Dec 2018Activity: Participating in or organising an event types › Contribution to conference
-
Trends in Pharmacological Sciences (Journal)
Celine Valant (Peer reviewer)
29 Mar 2018Activity: Publication peer-review and editorial work types › Peer review responsibility