Celine Valant

Senior Research Fellow, Drug Discovery Biology

https://orcid.org/0000-0002-2509-7465

EmailCeline.Valant@monash.edu

Research activity per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

Position

Post-doctoral Fellow
Faculty of Pharmacy and Pharmaceutical Sciences

Drug Discovery Biology
Monash Institute of Pharmaceutical Sciences

Research area keywords

GPCRs
Allostery
muscarinic receptor
Neurocognitive Processes

Network

Recent external collaboration on country level. Dive into details by clicking on the dots or

1 Active
3 Finished

Discovering novel allosteric probes of muscarinic acetylcholine receptors
Valant, C., Scammells, P. & Christopoulos, A.
3/06/19 → 2/06/22
Project: Research
Allosteric modulators of muscarinic acetylcholine receptors
Christopoulos, A. & Valant, C.
16/06/17 → 30/06/18
Project: Research
Understanding novel drug binding pockets at G protein-coupled receptors
Valant, C.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/15 → 31/12/17
Project: Research
Understanding endogenous allosteric modulators of G protein-coupled receptors
Valant, C.
Australian Research Council (ARC)
1/09/14 → 31/08/18
Project: Research

46 Article
2 Chapter (Book)
1 Comment / Debate
1 Review Article

Development of Novel 4-Arylpyridin-2-one and 6-Arylpyrimidin-4-one Positive Allosteric Modulators of the M₁ Muscarinic Acetylcholine Receptor
Jörg, M., Khajehali, E., van der Westhuizen, E. T., C. Choy, K. H., Shackleford, D. M., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 8 Jan 2021, In : ChemMedChem. 16, 1, p. 216-233 18 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Citation (Scopus)
Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse Colon
DiCello, J. J., Carbone, S. E., Saito, A., Rajasekhar, P., Ceredig, R. A., Pham, V., Valant, C., Christopoulos, A., Veldhuis, N. A., Canals, M., Massotte, D. & Poole, D. P., Mar 2020, In : Cellular and Molecular Gastroenterology and Hepatology. 9, 3, p. 465-483 19 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

3 Citations (Scopus)
Restoring Agonist Function at a Chemogenetically Modified M₁Muscarinic Acetylcholine Receptor
Khajehali, E., Bradley, S., Van Der Westhuizen, E. T., Molloy, C., Valant, C., Finlayson, L., Lindsley, C. W., Sexton, P. M., Tobin, A. B. & Christopoulos, A., 16 Dec 2020, In : ACS Chemical Neuroscience. 11, 24, p. 4270–4279 10 p.
Research output: Contribution to journal › Article › Research › peer-review
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M₁ mAChR: The Determinants of Allosteric Activity
Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

3 Citations (Scopus)
Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs
Hollingsworth, S. A., Kelly, B., Valant, C., Michaelis, J. A., Mastromihalis, O., Thompson, G., Venkatakrishnan, A. J., Hertig, S., Scammells, P. J., Sexton, P. M., Felder, C. C., Christopoulos, A. & Dror, R. O., 1 Dec 2019, In : Nature Communications. 10, 1, p. 1-9 9 p., 3289.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

13 Citations (Scopus)

Citation Award 2015
Valant, Celine (Recipient), 30 Jun 2015
Prize: Prize (including medals and awards)
Denis Wade Johnson & Johnson New Investigator Award 2012
Valant, Celine (Recipient), Dec 2012
Prize: Prize (including medals and awards)
Outstanding New Investigator Award 2012
Valant, Celine (Recipient), Dec 2012
Prize: Prize (including medals and awards)

14 Peer review responsibility
13 Contribution to conference
1 Contribution to workshop, seminar, course
1 Submissions to industry or govt committees, commissions and inquiries

MP-GPCR 2018
Celine Valant (Invited speaker)
2 Dec 2018 → 4 Dec 2018
Activity: Participating in or organising an event types › Contribution to conference
ASCEPT 2018
Celine Valant (Invited speaker)
26 Nov 2018 → 30 Nov 2018
Activity: Participating in or organising an event types › Contribution to conference
British Journal of Pharmacology (Journal)
Celine Valant (Peer reviewer)
9 Apr 2018 → 14 Sep 2018
Activity: Publication peer-review and editorial work types › Peer review responsibility
Introduction to advanced receptor pharmacology
Celine Valant (Organiser)
14 Oct 2018 → 19 Oct 2018
Activity: Participating in or organising an event types › Contribution to workshop, seminar, course
Trends in Pharmacological Sciences (Journal)
Celine Valant (Peer reviewer)
29 Mar 2018
Activity: Publication peer-review and editorial work types › Peer review responsibility