Projects per year
Personal profile
Biography
Céline Pattaroni is a Group Leader in the department of Immunology (STM) at Monash University and Program Lead within the Skin, Inflammation, Informatics and Neoplasia (SkIIN) Discovery Program. She specialises in systems immunology, with a focus on elucidating the cellular, microbial, and molecular architecture of human skin in both health and inflammatory disease. Her work integrates large-scale single-cell, epigenomic, transcriptomic, and microbiome datasets to construct a comprehensive, data-driven framework for understanding barrier immunity and the factors that drive immune heterogeneity across individuals and tissues.
Dr Pattaroni’s expertise spans computational biology, immunology, and host–microbe interactions. Before establishing her skin-focused research program, she contributed to international efforts in early-life respiratory research, characterising how microbial colonisation and immune maturation shape susceptibility to childhood wheeze and asthma. This early work laid the foundation for her current interest in how tissue environments, microbial communities, and immune networks interact to maintain homeostasis or promote pathology.
At Monash, she leads a multidisciplinary team at the interface of immunology and translational dermatology. Working closely with clinical and industry partners, her group develops analytical frameworks and integrative multi-omics approaches to elucidate the organisation and regulation of the barrier site microenvironment.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Bioinformatics
- Immunology
- Asthma
- Dermatology
- Data science
Collaborations and top research areas from the last five years
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Understanding Atopic Dermatitis Pathogenesis and Treatment Response through Multi-Omics Analysis
Kern, J. (Primary Chief Investigator (PCI)), Pattaroni, C. (Chief Investigator (CI)) & Marsland, B. (Chief Investigator (CI))
24/04/24 → 1/06/27
Project: Research
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Preventing asthma by deep diving into host-microbial interactions
Marsland, B. (Primary Chief Investigator (PCI)) & Pattaroni, C. (Chief Investigator (CI))
1/07/22 → 30/06/23
Project: Research
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Preventing asthma by deep diving into host-microbial interactions
Pattaroni, C. (Primary Chief Investigator (PCI))
1/07/21 → 1/07/24
Project: Research
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Harnessing tyrosine metabolism to combat respiratory diseases
Marsland, B. (Primary Chief Investigator (PCI)), Wypych, T. (Chief Investigator (CI)) & Pattaroni, C. (Chief Investigator (CI))
1/01/21 → 31/12/23
Project: Research
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Early life inter-kingdom interactions shape the immunological environment of the airways
Pattaroni, C., Macowan, M., Chatzis, R., Daunt, C., Custovic, A., Shields, M. D., Power, U. F., Grigg, J., Roberts, G., Ghazal, P., Schwarze, J., Gore, M., Turner, S., Bush, A., Saglani, S., Lloyd, C. M. & Marsland, B. J., Dec 2022, In: Microbiome. 10, 1, 16 p., 34.Research output: Contribution to journal › Article › Research › peer-review
Open Access29 Citations (Scopus) -
Early-Life Formation of the Microbial and Immunological Environment of the Human Airways
Pattaroni, C., Watzenboeck, M. L., Schneidegger, S., Kieser, S., Wong, N. C., Bernasconi, E., Pernot, J., Mercier, L., Knapp, S., Nicod, L. P., Marsland, C. P., Roth-Kleiner, M. & Marsland, B. J., 12 Dec 2018, In: Cell Host & Microbe. 24, 6, p. 857-865.e4 13 p.Research output: Contribution to journal › Article › Research › peer-review
153 Citations (Scopus) -
Lower airway microbiota associates with inflammatory phenotype in severe preschool wheeze
Robinson, P. F. M., Pattaroni, C., Cook, J., Gregory, L., Alonso, A. M., Fleming, L. J., Lloyd, C. M., Bush, A., Marsland, B. J. & Saglani, S., Apr 2019, In: Journal of Allergy and Clinical Immunology. 143, 4, p. 1607-1610 4 p.Research output: Contribution to journal › Article › Other › peer-review
52 Citations (Scopus) -
Bacterial communities co-develop with respiratory immunity early in life, linking dysbiosis to systemic monocyte signature and wheezing
Pattaroni, C. (Leading Author), Macowan, M., Chatzis, R., Iacono, G., Cardwell, B., Gore, M., Custovic, A., Shields, M. D., Powers, U. F., Grigg, J., Roberts, G., Ghazal, P., Schwarze, J., Turner, S., Bush, A., Saglani, S., Lloyd, C. M. & Marsland, B., Oct 2025, In: Science Advances. 11, 42, 14 p., eadw1410.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Deep multiomic profiling reveals molecular signatures that underpin preschool wheeze and asthma
Macowan, M., Pattaroni, C. (Leading Author), Bonner, K., Chatzis, R., Daunt, C., Gore, M., Custovic, A., Shields, M. D., Power, U. F., Grigg, J., Roberts, G., Ghazal, P., Schwarze, J., Turner, S., Bush, A., Saglani, S., Lloyd, C. M. & Marsland, B. J., Jan 2025, In: Journal of Allergy and Clinical Immunology. 155, 1, p. 94-106 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access11 Citations (Scopus)