Research output per year
Research output per year
Personal profile
Biography
Dr. Cathy Xie is a research fellow at the Australian Translational Medicinal Chemistry Facility (ATMCF) in Monash Institute of Pharmaceutical Sciences (MIPS). Her current project is in partnership with the Australian largest radiopharmaceutical company - Cyclotek, aiming at developing novel 18F-labelled radiotracers for PET imaging, as new and better diagnostics of various human cancers with potential in clinic application.
Cathy has a long-term research focus on drug discovery. She received her doctorate degree in Medicinal Chemistry from Monash University in 2020. Her PhD project is about developing novel GSTO1-1 inhibitors for the treatment of inflammatory conditions.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicinal Chemistry, Doctor of Philosophy, Development of GSTO1-1 inhibitors for the treatment of inflammatory conditions, MONASH UNIVERSITY
30 Sept 2016 → 2 Apr 2020
Award Date: 2 Apr 2020
Pharmaceutical Sciences, Bachelor of Science, China Pharmaceutical University
1 Sept 2012 → 30 Jun 2016
Award Date: 30 Jun 2016
Research area keywords
- Drug Discovery
- Medicinal Chemistry
- Chemical Biology
- Drug Development
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors
Xie, Y., Tummala, P., Oakley, A. J., Deora, G. S., Nakano, Y., Rooke, M., Cuellar, M. E., Strasser, J. M., Dahlin, J. L., Walters, M. A., Casarotto, M. G., Board, P. G. & Baell, J. B., 26 Mar 2020, In: Journal of Medicinal Chemistry. 63, 6, p. 2894-2914 21 p.Research output: Contribution to journal › Article › Research › peer-review
10 Citations (Scopus) -
Synthesis and structure-activity relationship study of pyrrolidine-oxadiazoles as anthelmintics against Haemonchus contortus
Ruan, B., Zhang, Y., Tadesse, S., Preston, S., Taki, A. C., Jabbar, A., Hofmann, A., Jiao, Y., Garcia-Bustos, J., Harjani, J., Le, T. G., Varghese, S., Teguh, S., Xie, Y., Odiba, J., Hu, M., Gasser, R. B. & Baell, J., 15 Mar 2020, In: European Journal of Medicinal Chemistry. 190, 8 p., 112100.Research output: Contribution to journal › Article › Research › peer-review
11 Citations (Scopus) -
Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation
Hughes, M. M., Hooftman, A., Angiari, S., Tummala, P., Zaslona, Z., Runtsch, M. C., McGettrick, A. F., Sutton, C. E., Diskin, C., Rooke, M., Takahashi, S., Sundararaj, S., Casarotto, M. G., Dahlstrom, J. E., Palsson-McDermott, E. M., Corr, S. C., Mills, K. H. G., Preston, R. J. S., Neamati, N., Xie, Y., & 3 others, 1 Oct 2019, In: Cell Reports. 29, 1, p. 151-161.e5 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile50 Citations (Scopus) -
Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example
Xie, Y., Dahlin, J. L., Oakley, A. J., Casarotto, M. G., Board, P. G. & Baell, J. B., 13 Sept 2018, In: Journal of Medicinal Chemistry. 61, 17, p. 7448-7470 23 p.Research output: Contribution to journal › Review Article › Research › peer-review
11 Citations (Scopus) -
GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity
Menon, D., Innes, A., Oakley, A. J., Dahlstrom, J. E., Jensen, L. M., Brüstle, A., Tummala, P., Rooke, M., Casarotto, M. G., Baell, J. B., Nguyen, N., Xie, Y., Cuellar, M., Strasser, J., Dahlin, J. L., Walters, M. A., Burgio, G., O'Neill, L. A. J. & Board, P. G., 1 Dec 2017, In: Scientific Reports. 7, 1, p. 1-15 15 p., 17832.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile35 Citations (Scopus)