Personal profile

Biography

Dr Catherine Carmichael is a group leader in the Centre for Cancer Research at the Hudson Institute of Medical Research, and adjunct Senior Research Fellow within the School of Clinical Sciences at Monash University. She completed her PhD and initial postdoctoral training at the Walter and Eliza Hall Institute between 2004-2013, before moving to the Australian Centre for Blood Diseases at Monash University in 2014. Catherine was recruited to the Hudson Institute in February 2022 to lead the Leukaemia Modelling and Therapeutic Discovery group.

Her research focuses on gaining an understanding of the molecular mechanisms driving Acute Myeloid Leukaemia (AML) development and pathogenesis; with the ultimate goal of identifying novel methods for therapeutically targeting this extremely poor outcome malignancy.

Currently accepting PhD and Honours students.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research area keywords

  • Acute Myeloid Leukemia
  • Hematopoiesis
  • Hematopoietic stem cells
  • Genetics
  • Molecular Genetics
  • Transcriptional regulation

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Germ line ERG haploinsufficiency defines a new syndrome with cytopenia and hematological malignancy predisposition

    Zerella, J. R., Homan, C. C., Arts, P., Lin, X., Spinelli, S. J., Venugopal, P., Babic, M., Brautigan, P. J., Truong, L., Arriola-Martinez, L., Moore, S., Hollins, R., Parker, W. T., Nguyen, H., Kassahn, K. S., Branford, S., Feurstein, S., Larcher, L., Sicre de Fontbrune, F. & Demirdas, S. & 32 others, de Munnik, S., Antoine-Poirel, H., Brichard, B., Mansour, S., Gordon, K., Wlodarski, M. W., Koppayi, A., Dobbins, S., Mutsaers, P. G. N. J., Nichols, K. E., Oak, N., DeMille, D., Mao, R., Crawford, A., McCarrier, J., Basel, D., Flores-Daboub, J., Drazer, M. W., Phillips, K., Poplawski, N. K., Birdsey, G. M., Pirri, D., Ostergaard, P., Simons, A., Godley, L. A., Ross, D. M., Hiwase, D. K., Soulier, J., Carmichael, C. L., Scott, H. S., Hahn, C. N. & ERG Variants Research Network, 24 Oct 2024, In: Blood. 144, 17, p. 1765-1780 16 p.

    Research output: Contribution to journalArticleResearchpeer-review

    Open Access
    8 Citations (Scopus)
  • Patient-Derived Xenograft Models for Leukemias

    Brown, F. C. & Carmichael, C. L., 2024, Patient-Derived Xenografts: Methods and Protocols. Saad, M. I. (ed.). 1st ed. New York NY USA: Humana Press, p. 31-40 10 p. (Methods in Molecular Biology; vol. 2806).

    Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

    2 Citations (Scopus)
  • Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity

    Wang, J., Farkas, C., Benyoucef, A., Carmichael, C., Haigh, K., Wong, N., Huylebroeck, D., Stemmler, M. P., Brabletz, S., Brabletz, T., Nefzger, C. M., Goossens, S., Berx, G., Polo, J. M. & Haigh, J. J., Sept 2021, In: PLoS Biology. 19, 9, 33 p., e3001394.

    Research output: Contribution to journalArticleResearchpeer-review

    Open Access
    28 Citations (Scopus)
  • Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

    Fagnan, A., Bagger, F. O., Piqué-Borràs, M. R., Ignacimouttou, C., Caulier, A., Lopez, C. K., Robert, E., Uzan, B., Gelsi-Boyer, V., Aid, Z., Thirant, C., Moll, U., Tauchmann, S., Kurtovic-Kozaric, A., Maciejewski, J., Dierks, C., Spinelli, O., Salmoiraghi, S., Pabst, T. & Shimoda, K. & 24 others, Deleuze, V., Lapillonne, H., Sweeney, C., De Mas, V., Leite, B., Kadri, Z., Malinge, S., de Botton, S., Micol, J. B., Kile, B., Carmichael, C. L., Iacobucci, I., Mullighan, C. G., Carroll, M., Valent, P., Bernard, O. A., Delabesse, E., Vyas, P., Birnbaum, D., Anguita, E., Garçon, L., Soler, E., Schwaller, J. & Mercher, T., 6 Aug 2020, In: Blood. 136, 6, p. 698-714 17 p.

    Research output: Contribution to journalArticleResearchpeer-review

    34 Citations (Scopus)
  • RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML

    Brown, A. L., Arts, P., Carmichael, C. L., Babic, M., Dobbins, J., Chong, C. E., Schreiber, A. W., Feng, J., Phillips, K., Wang, P. P. S., Ha, T., Homan, C. C., King-Smith, S. L., Rawlings, L., Vakulin, C., Dubowsky, A., Burdett, J., Moore, S., McKavanagh, G. & Henry, D. & 39 others, Wells, A., Mercorella, B., Nicola, M., Suttle, J., Wilkins, E., Li, X. C., Michaud, J., Brautigan, P., Cannon, P., Altree, M., Jaensch, L., Fine, M., Butcher, C., D'Andrea, R. J., Lewis, I. D., Hiwase, D. K., Papaemmanuil, E., Horwitz, M. S., Natsoulis, G., Rienhoff, H. Y., Patton, N., Mapp, S., Susman, R., Morgan, S., Cooney, J., Currie, M., Popat, U., Bochtler, T., Izraeli, S., Bradstock, K., Godley, L. A., Kr¨amer, A., Fröhling, S., Wei, A. H., Forsyth, C., Fan, H. M., Poplawski, N. K., Hahn, C. N. & Scott, H. S., 24 Mar 2020, In: Blood Advances. 4, 6, p. 1131-1144 14 p.

    Research output: Contribution to journalArticleResearchpeer-review

    Open Access
    File
    129 Citations (Scopus)