Projects per year
Personal profile
Biography
Dr Catherine Carmichael is a group leader in the Centre for Cancer Research at the Hudson Institute of Medical Research, and adjunct Senior Research Fellow within the School of Clinical Sciences at Monash University. She completed her PhD and initial postdoctoral training at the Walter and Eliza Hall Institute between 2004-2013, before moving to the Australian Centre for Blood Diseases at Monash University in 2014. Catherine was recruited to the Hudson Institute in February 2022 to lead the Leukaemia Modelling and Therapeutic Discovery group.
Her research focuses on gaining an understanding of the molecular mechanisms driving Acute Myeloid Leukaemia (AML) development and pathogenesis; with the ultimate goal of identifying novel methods for therapeutically targeting this extremely poor outcome malignancy.
Currently accepting PhD and Honours students.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Acute Myeloid Leukemia
- Hematopoiesis
- Hematopoietic stem cells
- Genetics
- Molecular Genetics
- Transcriptional regulation
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Development of a new broadly applicable therapeutic strategy for Acute Myeloid Leukaemia
Carmichael, C., Holien, J. K., Herold, M., Shortt, J., Brown, F., Rosenbluh, S., Lukeman, S. & English, R.
16/01/22 → 16/01/27
Project: Research
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Understanding the roles of the EMT transcription factors in epigenetic remodelling and myeloid cell transformation.
Carmichael, C. & Haigh, J.
1/01/18 → 31/12/20
Project: Research
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Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity
Wang, J., Farkas, C., Benyoucef, A., Carmichael, C., Haigh, K., Wong, N., Huylebroeck, D., Stemmler, M. P., Brabletz, S., Brabletz, T., Nefzger, C. M., Goossens, S., Berx, G., Polo, J. M. & Haigh, J. J., Sep 2021, In: PLoS Biology. 19, 9, 33 p., e3001394.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers
Fagnan, A., Bagger, F. O., Piqué-Borràs, M. R., Ignacimouttou, C., Caulier, A., Lopez, C. K., Robert, E., Uzan, B., Gelsi-Boyer, V., Aid, Z., Thirant, C., Moll, U., Tauchmann, S., Kurtovic-Kozaric, A., Maciejewski, J., Dierks, C., Spinelli, O., Salmoiraghi, S., Pabst, T., Shimoda, K., & 24 others, 6 Aug 2020, In: Blood. 136, 6, p. 698-714 17 p.Research output: Contribution to journal › Article › Research › peer-review
23 Citations (Scopus) -
RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML
Brown, A. L., Arts, P., Carmichael, C. L., Babic, M., Dobbins, J., Chong, C. E., Schreiber, A. W., Feng, J., Phillips, K., Wang, P. P. S., Ha, T., Homan, C. C., King-Smith, S. L., Rawlings, L., Vakulin, C., Dubowsky, A., Burdett, J., Moore, S., McKavanagh, G., Henry, D., & 39 others, 24 Mar 2020, In: Blood Advances. 4, 6, p. 1131-1144 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile61 Citations (Scopus) -
The EMT Modulator SNAI1 Contributes to AML Pathogenesis via Its Interaction With LSD1
Carmichael, C. L., Wang, J., Nguyen, T., Kolawole, O., Benyoucef, A., De Mazière, C., Milne, A. R., Samuel, S., Gillinder, K., Hediyeh-Zadeh, S., Vo, N., Huang, Y., Knezevic, K., McInnes, W. R. L., Shields, B. J., Mitchell, H., Ritchie, M. E., Lammens, T., Lintermans, B., Van Vlierberghe, P., & 17 others, 20 Aug 2020, In: Blood. 136, 8, p. 957-973 17 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile23 Citations (Scopus) -
Genomic subtyping and therapeutic targeting of acute erythroleukemia
Iacobucci, I., Wen, J., Meggendorfer, M., Choi, J. K., Shi, L., Pounds, S. B., Carmichael, C. L., Masih, K. E., Morris, S. M., Lindsley, R. C., Janke, L. J., Alexander, T. B., Song, G., Qu, C., Li, Y., Payne-Turner, D., Tomizawa, D., Kiyokawa, N., Valentine, M., Valentine, V., & 28 others, Apr 2019, In: Nature Genetics. 51, 4, p. 694-704 11 p.Research output: Contribution to journal › Article › Research › peer-review
77 Citations (Scopus)