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Catherine Carmichael

Dr

20072020
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Personal profile

Biography

Dr Catherine Carmichael completed her PhD and initial postdoctoral training at the Walter and Eliza Hall Institute between 2004-2013. In 2014 she took up a Research Fellow position at the Australian Centre for Blood Diseases at Monash University, and in 2019 became Acting Group Leader of the Mammalian Functional Genetics Group. Her research focuses on gaining an understanding of the molecular mechanisms driving Acute Myeloid Leukaemia (AML) development and pathogenesis; with the ultimate goal of identifying novel methods for therapeutically targeting this extremely poor outcome malignancy.

Keywords

  • Acute Myeloid Leukemia
  • Hematopoiesis
  • Hematopoietic stem cells
  • Genetics
  • Molecular Genetics
  • Transcriptional regulation

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Projects 2018 2020

Understanding the roles of the EMT transcription factors in epigenetic remodelling and myeloid cell transformation.

Carmichael, C. & Haigh, J.

1/01/18 → 31/12/20

Project: Research

Research Output 2007 2019

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Iacobucci, I., Wen, J., Meggendorfer, M., Choi, J. K., Shi, L., Pounds, S. B., Carmichael, C. L., Masih, K. E., Morris, S. M., Lindsley, R. C., Janke, L. J., Alexander, T. B., Song, G., Qu, C., Li, Y., Payne-Turner, D., Tomizawa, D., Kiyokawa, N., Valentine, M., Valentine, V. & 28 othersBasso, G., Locatelli, F., Enemark, E. J., Kham, S. K. Y., Yeoh, A. E. J., Ma, X., Zhou, X., Sioson, E., Rusch, M., Ries, R. E., Stieglitz, E., Hunger, S. P., Wei, A. H., To, L. B., Lewis, I. D., D’Andrea, R. J., Kile, B. T., Brown, A. L., Scott, H. S., Hahn, C. N., Marlton, P., Pei, D., Cheng, C., Loh, M. L., Ebert, B. L., Meshinchi, S., Haferlach, T. & Mullighan, C. G., Apr 2019, In : Nature Genetics. 51, 4, p. 694-704 11 p.

Research output: Contribution to journal › Article › Research › peer-review

Low-Fouling and Biodegradable Protein-Based Particles for Thrombus Imaging

Bonnard, T., Jayapadman, A., Putri, J. A., Cui, J., Ju, Y., Carmichael, C., Angelovich, T. A., Cody, S. H., French, S., Pascaud, K., Pearce, H. A., Jagdale, S., Caruso, F. & Hagemeyer, C. E., 24 Jul 2018, In : ACS Nano. 12, 7, p. 6988-6996 9 p.

Research output: Contribution to journal › Article › Research › peer-review

ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia

Thirant, C., Ignacimouttou, C., Lopez, C. K., Diop, MB., Le Mouël, L., Thiollier, C., Siret, A., Dessen, P., Aid, Z., Rivière, J., Rameau, P., Lefebvre, C., Khaled, M., Leverger, G., Ballerini, P., Petit, A., Raslova, H., Carmichael, C. L., Kile, B. T., Soler, E. & 10 othersCrispino, J. D., Wichmann, C., Pflumio, F., Schwaller, J., Vainchenker, W., Lobry, C., Droin, N., Bernard, O. A., Malinge, S. & Mercher, T., 13 Mar 2017, In : Cancer Cell. 31, 3, p. 452-465 14 p.

Research output: Contribution to journal › Article › Research › peer-review

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

Goossens, S., Peirs, S., Loocke, W. V., Wang, J., Takawy, M., Matthijssens, F., Sonderegger, S. E., Haigh, K., Nguyen, T., Vandamme, N., Costa, M., Carmichael, C., Van Nieuwerburgh, F., Deforce, D., Kleifeld, O., Curtis, D. J., Berx, G., Van Vlierberghe, P. & Haigh, J. J., 23 Feb 2017, In : Blood. 129, 8, p. 981-990 10 p.

Research output: Contribution to journal › Article › Research › peer-review

The Snail Family in Normal and Malignant Haematopoiesis

Carmichael, C. L. & Haigh, J. J., 1 Feb 2017, In : Cells Tissues Organs. 203, 2, p. 82-98 17 p.

Research output: Contribution to journal › Article › Research › peer-review