20112018
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Research Output 2011 2018

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2018

CD4+ T cell-mediated HLA class II cross-restriction in HIV controllers

Galperin, M., Farenc, C., Mukhopadhyay, M., Jayasinghe, D., Decroos, A., Benati, D., Tan, L. L., Ciacchi, L., Reid, H. H., Rossjohn, J., Chakrabarti, L. & Gras, S., 8 Jun 2018, In : Science Immunology. 3, 24, 13 p., eaat0687.

Research output: Contribution to journalArticleResearchpeer-review

2017

A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors

Sullivan, L. C., Walpole, N. G., Farenc, C., Pietra, G., Sum, M. J. W., Clements, C. S., Lee, E. J., Beddoe, T., Falco, M., Mingari, M. C., Moretta, L., Gras, S., Rossjohn, J. & Brooks, A. G., 22 Dec 2017, In : Journal of Biological Chemistry. 292, 51, p. 21149-21158 10 p.

Research output: Contribution to journalArticleResearchpeer-review

A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene

Van Braeckel-Budimir, N., Gras, S., Ladell, K., Josephs, T. M., Pewe, L., Urban, S. L., Miners, K. L., Farenc, C., Price, D. A., Rossjohn, J. & Harty, J. T., 21 Nov 2017, In : Immunity. 47, 5, p. 835-847 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8 + T cell response

Culshaw, A., Ladell, K., Gras, S., McLaren, J. E., Miners, K. L., Farenc, C., Van Den Heuvel, H., Gostick, E., Dejnirattisai, W., Wangteeraprasert, A., Duangchinda, T., Chotiyarnwong, P., Limpitikul, W., Vasanawathana, S., Malasit, P., Dong, T., Rossjohn, J., Mongkolsapaya, J., Price, D. A. & Screaton, G. R., 18 Oct 2017, In : Nature Immunology. 18, 11, p. 1228-1237 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Reversed T cell receptor docking on a major histocompatibility class I complex limits involvement in the immune response

Gras, S., Chadderton, J., Del Campo, C. M., Farenc, C., Wiede, F., Josephs, T. M., Sng, X. Y. X., Mirams, M., Watson, K. A., Tiganis, T., Quinn, K. M., Rossjohn, J. & La Gruta, N. L., 18 Oct 2016, In : Immunity. 45, 4, p. 749-760 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

The targeted recognition of Lactococcus lactis phages to their polysaccharide receptors

McCabe, O., Spinelli, S., Farenc, C., Labbé, M., Tremblay, D., Blangy, S., Oscarson, S., Moineau, S. & Cambillau, C., 1 May 2015, In : Molecular Microbiology. 96, 4, p. 875-886 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

Molecular insights on the recognition of a Lactococcus lactis cell wall pellicle by the phage 1358 receptor binding protein

Farenc, C., Spinelli, S., Vinogradov, E., Tremblay, D., Blangy, S., Sadovskaya, I., Moineau, S. & Cambillau, C., Jun 2014, In : Journal of Virology. 88, 12, p. 7005-7015 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2013

A Toxin-Antitoxin Module of Salmonella Promotes Virulence in Mice

Cruz, M. A., Zhao, W., Farenc, C., Gimenez, G., Raoult, D., Cambillau, C., Gorvel, J. P. & Méresse, S., 2013, In : PLoS Pathogens. 9, 12, e1003827.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Structure, adsorption to host, and infection mechanism of virulent lactococcal phage p2

Bebeacua, C., Tremblay, D., Farenc, C., Chapot-Chartier, M. P., Sadovskaya, I., van Heel, M., Veesler, D., Moineau, S. & Cambillau, C., 2013, In : Journal of Virology. 87, 22, p. 12302-12312 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Viral infection modulation and neutralization by camelid nanobodies

Desmyter, A., Farenc, C., Mahony, J., Spinelli, S., Bebeacua, C., Blangy, S., Veesler, D., van Sinderen, D. & Cambillau, C., 9 Apr 2013, In : Proceedings of the National Academy of Sciences. 110, 15

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2012

Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase

Van Linden, O. P. J., Farenc, C., Zoutman, W. H., Hameetman, L., Wijtmans, M., Leurs, R., Tensen, C. P., Siegal, G. & de Esch, I. J. P., Jan 2012, In : European Journal of Medicinal Chemistry. 47, 1, p. 493-500 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Crystal structure of the EphA4 protein tyrosine kinase domain in the apo- and dasatinib-bound state

Farenc, C., Celie, P. H. N., Tensen, C. P., de Esch, I. J. P. & Siegal, G., 16 Nov 2011, In : FEBS Letters. 585, 22, p. 3593-3599 7 p.

Research output: Contribution to journalArticleResearchpeer-review