Projects per year
Personal profile
Biography
A/Prof. Semple is a dedicated neuroscientist with a growing national and international reputation for excellence in neurotrauma research. She leads the Paediatric Neurotrauma Group in the Department of Neuroscience at Monash University’s Central Clinical School. The team is comprised of research assistants and PhD, Masters and Honours students, all working on various questions regarding the fundamental neurobiology of traumatic brain injuries across the lifespan.
A/Prof. Semple has received substantial competitive fellowship and grant funding, totalling <$2.5M to date, from the NHMRC, US Department of Defense, Veski, American Australian Association, Rebecca L Cooper Medical Research Foundation, Monash University and Capstone Editing. With a H-index of 30, her peer-reviewed published research has garnered almost 5000 citations to date.
A/Prof. Semple sits on the Executive Board for the International Neurotrauma Society, and the Council for the US National Neurotrauma Society (past-Secretary, 2021-22). She is also a coordinating member of the Australasian Neurotrauma Workshop annual scientific conference. A/Prof. Semple sits on several journal editorial boards including Experimental Neurology, Frontiers in Neurology (Neurotrauma) and Neurotrauma Reports.
Locally, A/Prof. Semple is a member of the Central Clinical School’s Consumer and Researcher Engagement (CaRE) program committee, and Chair of the User Group Committee for the Monash Micro Imaging A+ Alliance node. In 2022, She was awarded the inaugural Mid-Career Excellence in Leadership Award from Monash University’s Central Clinical School Gender, Equity, Diversity and Inclusion (GEDI) committee.
A/Prof. Semple completed her PhD at Monash University in 2010, followed by postdoctoral training at the University of California San Francisco (2011-2015) and University of Melbourne (2015-2017), before establishing her independent group at Monash University in 2018.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Honorary Research Fellow, University of Melbourne
1 Jan 2018 → …
Research area keywords
- neuroinflammation
- paediatric
- traumatic brain injury
- neurotrauma
- animal models
- epilepsy
- social behaviour
- Brain injury
- seizures
Network
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An informatics approach to predict outcomes and monitor intervention efficacy following moderate to severe traumatic brain injury
Fitzgerald, M., Gabbe, B., Lannin, N., Vallmuur, K., Curtis, K., Harrison, J., Young, J. T., Menon, D. K., Cullen, J. C., Armstrong, E., Eades, S., Cameron, P., Cooper, J., Fitzgerald, M., Balogh, Z., Fatovich, D., Honeybul, S., Jeffree, R. L., McNamara, R., Mitchell, G. J., Delaney, A., Reade, M. C., Wells, A., Williams, J., Ponsford, J., McDonald, S., Kendall, E., Ownsworth , T., Simpson, G., Togher, L., Hassett, L., Fleming, J., Williams, G. P., Collins-Praino, L. E., Reeder, S., Mobbs, R., Vickers, J., Anderson, V., Barlow, K., Holland, A. J. A., Scheinberg, A., Semple, B., Parizel, P. M., O'Brien, T., Law, M., Rose, S. E., Varma, D., Nasrallah, F., Shultz, S., Hellewell, S., Bosio, E., King , K., Parr, M., Udy, A., Hill, A. F., Olver, J., Teague, W. J., Egan, G., Fisher, M., York, L., Bynevelt, M., Maas, A. I., O'Reilly, G., McDonald, S., Capell, J., Gilroy, J., Walsham, J., Newcombe, V., Geraghty, T. J., Joyce, C. J., Rosenfeld, J., Elcock, M., Ross, J., Bragge, P., Meka, S., Chai, K., Cowen, G., Hasseler, L., Ercole, A., Wagland , J., Alexander, T., Babl, F. E., Bidargaddi, N., Mahoney, A. J., Wright, D., Crowe, L. M., Robinson, S., Rushworth, N., Hansen, M., Ellis, D., Zeeman, H., Francis, R., Whiley, L. & Reid, C.
1/07/21 → 30/06/23
Project: Research
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Infections promote post-traumatic epilepsy and poor outcomes after traumatic brain injury
Semple, B., O'Brien, T. & Li, J.
United States Department of Defense (DOD)
4/01/21 → 29/09/23
Project: Research
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Polarization of immune cells by novel compounds
Ali, I., Jones, N., Monif, M. & Semple, B.
Katholieke Universiteit Leuven (KU Leuven) (Catholic University of Leuven)
13/07/20 → 12/09/21
Project: Research
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A new player in microglial activation driving inflammation and pathology in traumatic brain injury [TBI].
25/03/19 → 24/03/20
Project: Research
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Ccr2 Gene Ablation Does Not Influence Seizure Susceptibility, Tissue Damage, or Cellular Inflammation after Murine Pediatric Traumatic Brain Injury
Sharma, R., Chu, E., Dill, L. K., Shad, A., Zamani, A., O'Brien, T. J., Casillas-Espinosa, P. M., Shultz, S. R. & Semple, B. D., 1 Feb 2023, In: Journal of Neurotrauma. 40, 3-4, p. 365-382 18 p.Research output: Contribution to journal › Article › Research › peer-review
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Pre-existing Toxoplasma gondii infection increases susceptibility to pentylenetetrazol-induced seizures independent of traumatic brain injury in mice
Baker, T. L., Uboldi, A. D., Tonkin, C. J., Wright, D. K., Vo, A., Wilson, T., Mychasiuk, R., McDonald, S. J., Semple, B. D., Sun, M. & Shultz, S. R., 5 Jan 2023, In: Frontiers in Molecular Neuroscience. 15, 16 p., 1079097.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
A companion to the preclinical common data elements for rodent genetic epilepsy models. A report of the TASK3-WG1B: Paediatric and genetic models working group of the ILAE/AES joint translational TASK force
Mantegazza, M., Auvin, S., Barker-Haliski, M., Katsarou, A. M., Kubova, H., Galanopoulou, A. S., Semple, B. & Reid, C. A., 2022, (Accepted/In press) In: Epilepsia Open. 13 p.Research output: Contribution to journal › Article › Other › peer-review
Open Access1 Citation (Scopus) -
A companion to the preclinical common data elements for rodent models of pediatric acquired epilepsy: A report of the TASK3-WG1B, Pediatric and Genetic Models Working Group of the ILAE/AES Joint Translational Task Force
Katsarou, A-M., Kubova, H., Auvin, S., Mantegazza, M., Barker-Haliski, M., Galanopoulou, A. S., Reid, C. A. & Semple, B. D., 2022, (Accepted/In press) In: Epilepsia Open. 34 p.Research output: Contribution to journal › Article › Other › peer-review
Open Access2 Citations (Scopus) -
Editorial: Long-term consequences of pediatric traumatic brain injury: Improved understanding to help young patients survive and thrive
Huh, J., Semple, B. D. & Raghupathi, R., 9 Sep 2022, In: Frontiers in Neurology. 13, 3 p., 1011998.Research output: Contribution to journal › Editorial › Other › peer-review
Open Access
Prizes
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Advancing Women's Research Success Grant
Semple, Bridgette (Recipient), 2018
Prize: Prize (including medals and awards)