Projects per year
Personal profile
Biography
Dr. Semple is an NHMRC R.D. Wright Biomedical Career Development Fellowship recipient and Head of the Paediatric Neurotrauma Group in the Department of Neuroscience, Monash University, Central Clinical School. Her research focuses on the acute and chronic neuropathology after traumatic injury to both the adult and pediatric brain, with a particular interest in neuroinflammation and behavioural outcomes. After obtaining her PhD at Monash University in 2010, Dr. Semple completed postdoctoral training at the University of California San Francisco, USA. Returning to Australia in 2015, she established a preclinical laboratory team at the University of Melbourne, before coming full circle back to Monash in January 2018.
External positions
Honorary Research Fellow, University of Melbourne
1 Jan 2018 → …Research area keywords
- neuroinflammation
- paediatric
- traumatic brain injury
- neurotrauma
- animal models
- epilepsy
- social behaviour
- Brain injury
- seizures
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
Long-term outcomes after paediatric traumatic brain injury
National Health & Medical Research Council (NHMRC)
1/01/18 → 31/12/21
Project: Research
A new player in microglial activation driving inflammation and pathology in traumatic brain injury [TBI].
25/03/19 → 24/03/20
Project: Research
NHMRC Equipment Grant - Quanterix SIMOA HD-1 Analyser
Shultz, S., Kwan, P., Medcalf, R., O'Brien, T., Mitra, B., Coughlan, M., Jones, N., Van Der Walt, A., Butzkueven, H., Semple, B. & Hutton, E.
Monash University – Internal Department Contribution, Monash University – Internal Faculty Contribution, Novartis Pharmaceuticals Australia Ltd
1/01/19 → 31/12/19
Project: Research
Research Output
Immune challenges and seizures: How do early life insults influence epileptogenesis?
Semple, B. D., Dill, L. K. & O'Brien, T. J., 1 Jan 2020, In : Frontiers in Pharmacology. 11, 14 p., 00002.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
Potential Neuroprotective Effect of the HMGB1 Inhibitor Glycyrrhizin in Neurological Disorders
Paudel, Y. N., Angelopoulou, E., Semple, B., Piperi, C., Othman, I. & Shaikh, M. F., 19 Feb 2020, In : ACS Chemical Neuroscience. 11, 4, p. 485-500 16 p.Research output: Contribution to journal › Review Article › Research › peer-review
Validation of reference genes for gene expression analysis following experimental traumatic brain injury in a pediatric mouse model
Zamani, A., Powell, K. L., May, A. & Semple, B. D., 1 Mar 2020, In : Brain Research Bulletin. 156, p. 43-49 7 p.Research output: Contribution to journal › Article › Research › peer-review
Affective, neurocognitive and psychosocial disorders associated with traumatic brain injury and post-traumatic epilepsy
Semple, B. D., Zamani, A., Rayner, G., Shultz, S. R. & Jones, N. C., 1 Mar 2019, In : Neurobiology of Disease. 123, p. 27-41 15 p.Research output: Contribution to journal › Review Article › Research › peer-review
10
Citations
(Scopus)
Age-dependent release of high-mobility group box protein-1 and cellular neuroinflammation after traumatic brain injury in mice
Webster, K. M., Sun, M., Crack, P. J., O'Brien, T. J., Shultz, S. R. & Semple, B. D., 15 Apr 2019, In : Journal of Comparative Neurology. 527, 6, p. 1102-1117 16 p.Research output: Contribution to journal › Article › Research › peer-review
2
Citations
(Scopus)
Prizes
Advancing Women's Research Success Grant
Bridgette Semple (Recipient), 2018
Prize: Prize (including medals and awards)