Projects per year
Personal profile
Biography
Dr. Semple is an NHMRC R.D. Wright Biomedical Career Development Fellowship recipient and Head of the Paediatric Neurotrauma Group in the Department of Neuroscience, Monash University, Central Clinical School. Her research focuses on the acute and chronic neuropathology after traumatic injury to both the adult and pediatric brain, with a particular interest in neuroinflammation and behavioural outcomes. After obtaining her PhD at Monash University in 2010, Dr. Semple completed postdoctoral training at the University of California San Francisco, USA. Returning to Australia in 2015, she established a small laboratory team at the University of Melbourne, before coming full circle back to Monash in 2018.
External positions
Honorary Research Fellow, The University of Melbourne
1 Jan 2018 → …Keywords
- Neuroinflammation
- paediatric
- traumatic brain injury
- neurotrauma
- animal models
- epilepsy
- social behaviour
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2018 2021
- 4 Active
A new player in microglial activation driving inflammation and pathology in traumatic brain injury [TBI].
25/03/19 → 24/03/20
Project: Research
NHMRC Equipment Grant - Quanterix SIMOA HD-1 Analyser
Shultz, S., Kwan, P., Medcalf, R., O'Brien, T., Mitra, B., Coughlan, M., Jones, N., Van Der Walt, A., Butzkueven, H., Semple, B. & Hutton, E.
Monash University – Internal Department Contribution, Monash University – Internal Faculty Contribution, Novartis Pharmaceuticals Australia Ltd
1/01/19 → 31/12/19
Project: Research
Long-term outcomes after paediatric traumatic brain injury
National Health & Medical Research Council (NHMRC)
1/01/18 → 31/12/21
Project: Research
Research Output 2010 2019
Age-dependent release of high-mobility group box protein-1 and cellular neuroinflammation after traumatic brain injury in mice
Webster, K. M., Sun, M., Crack, P. J., O'Brien, T. J., Shultz, S. R. & Semple, B. D., 15 Apr 2019, In : Journal of Comparative Neurology. 527, 6, p. 1102-1117 16 p.Research output: Contribution to journal › Article › Research › peer-review
Aged rats have an altered immune response and worse outcomes after traumatic brain injury
Sun, M., Brady, R. D., Casillas-Espinosa, P. M., Wright, D. K., Semple, B. D., Kim, H. A., Mychasiuk, R., Sobey, C. G., O'Brien, T. J., Vinh, A., McDonald, S. J. & Shultz, S. R., 1 Jan 2019, (Accepted/In press) In : Brain, Behavior, and Immunity. p. 1-15 15 p.Research output: Contribution to journal › Article › Research › peer-review
Determinants of social behavior deficits and recovery after pediatric traumatic brain injury
Zamani, A., Mychasiuk, R. & Semple, B. D., 1 Apr 2019, In : Experimental Neurology. 314, p. 34-45 12 p.Research output: Contribution to journal › Review Article › Research › peer-review
High mobility group box 1 (HMGB1) as a novel frontier in epileptogenesis: from pathogenesis to therapeutic approaches
Paudel, Y. N., Semple, B. D., Jones, N. C., Othman, I. & Shaikh, M. F., 1 Jan 2019, (Accepted/In press) In : Journal of Neurochemistry. p. 1-16 16 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
Infections after a traumatic brain injury: The complex interplay between the immune and neurological systems
Sharma, R., Shultz, S. R., Robinson, M. J., Belli, A., Hibbs, M. L., O'Brien, T. J. & Semple, B. D., 1 Jan 2019, (Accepted/In press) In : Brain, Behavior, and Immunity. 12 p.Research output: Contribution to journal › Review Article › Research › peer-review