Projects per year
Personal profile
Biography
Dr. Semple is an NHMRC R.D. Wright Biomedical Career Development Fellowship recipient and Head of the Paediatric Neurotrauma Group in the Department of Neuroscience, Monash University, Central Clinical School. Her research focuses on the acute and chronic neuropathology after traumatic injury to both the adult and pediatric brain, with a particular interest in neuroinflammation and behavioural outcomes. After obtaining her PhD at Monash University in 2010, Dr. Semple completed postdoctoral training at the University of California San Francisco, USA. Returning to Australia in 2015, she established a preclinical laboratory team at the University of Melbourne, before coming full circle back to Monash in January 2018.
External positions
Honorary Research Fellow, University of Melbourne
1 Jan 2018 → …
Research area keywords
- neuroinflammation
- paediatric
- traumatic brain injury
- neurotrauma
- animal models
- epilepsy
- social behaviour
- Brain injury
- seizures
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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An informatics approach to predict outcomes and monitor intervention efficacy following moderate to severe traumatic brain injury
Fitzgerald, M., Gabbe, B., Lannin, N., Vallmuur, K., Curtis, K., Harrison, J., Young, J. T., Menon, D. K., Cullen, J. C., Armstrong, E., Eades, S., Cameron, P., Cooper, J., Fitzgerald, M., Balogh, Z., Fatovich, D., Honeybul, S., Jeffree, R. L., McNamara, R., Mitchell, G., Delaney, A., Reade, M. C., Wells, A., Williams, J., Ponsford, J., McDonald, S., Kendall, E., Ownsworth , T., Simpson, G., Togher, L., Hassett, L., Fleming, J., Williams, G. P., Collins-Praino, L. E., Reeder, S., Mobbs, R., Vickers, J., Anderson, V., Barlow, K., Holland, A. J. A., Scheinberg, A., Semple, B., Parizel, P. M., O'Brien, T., Law, M., Rose, S. E., Varma, D., Nasrallah, F., Shultz, S., Hellewell, S., Bosio, E., King , K., Parr, M., Udy, A., Hill, A. F., Olver, J., Teague, W. J., Egan, G., Fisher, M., York, L., Bynevelt, M., Maas, A. I., O'Reilly, G., McDonald, S., Capell, J., Gilroy, J., Walsham, J., Newcombe, V., Geraghty, T. J., Joyce, C. J., Rosenfeld, J., Elcock, M., Ross, J., Bragge, P., Meka, S., Chai, K., Cowen, G., Hasseler, L., Ercole, A., Wagland , J., Alexander, T., Babl, F. E., Bidargaddi, N., Mahoney, A. J., Wright, D., Crowe, L. M., Robinson, S., Rushworth, N., Hansen, M., Ellis, D., Zeeman, H., Francis, R., Whiley, L. & Reid, C.
1/07/21 → 30/06/23
Project: Research
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Infections promote post-traumatic epilepsy and poor outcomes after traumatic brain injury
Semple, B., O'Brien, T. & Li, J.
United States Department of Defense (DOD)
4/01/21 → 29/09/23
Project: Research
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Polarization of immune cells by novel compounds
Ali, I., Jones, N., Monif, M. & Semple, B.
Katholieke Universiteit Leuven (KU Leuven) (Catholic University of Leuven)
13/07/20 → 12/09/21
Project: Research
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A new player in microglial activation driving inflammation and pathology in traumatic brain injury [TBI].
25/03/19 → 24/03/20
Project: Research
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NHMRC Equipment Grant - Quanterix SIMOA HD-X Analyser
Shultz, S., Kwan, P., Medcalf, R., O'Brien, T., Mitra, B., Coughlan, M., Jones, N., Van Der Walt, A., Butzkueven, H., Semple, B. & Hutton, E.
Monash University – Internal Faculty Contribution, Monash University – Internal Department Contribution
1/01/19 → 31/12/19
Project: Research
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Acute treatment with TrkB agonist LM22A-4 confers neuroprotection and preserves myelin integrity in a mouse model of pediatric traumatic brain injury
Fletcher, J. L., Dill, L. K., Wood, R. J., Wang, S., Robertson, K., Murray, S. S., Zamani, A. & Semple, B. D., May 2021, In: Experimental Neurology. 339, 15 p., 113652.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus) -
A Pro-social Pill? The Potential of Pharmacological Treatments to Improve Social Outcomes After Pediatric Traumatic Brain Injury
Semple, B. D. & Raghupathi, R., Aug 2021, In: Frontiers in Neurology. 12, 9 p., 714253.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access -
A systemic immune challenge to model hospital-acquired infections independently regulates immune responses after pediatric traumatic brain injury
Sharma, R., Zamani, A., Dill, L. K., Sun, M., Chu, E., Robinson, M. J., O’Brien, T. J., Shultz, S. R. & Semple, B. D., 17 Mar 2021, In: Journal of Neuroinflammation. 18, 1, 23 p., 72.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Corrigendum to “Acute treatment with TrkB agonist LM22A-4 confers neuroprotection and preserves myelin integrity in a mouse model of pediatric traumatic brain injury” (Experimental Neurology (2021) 339, (113652), (S0014488621000571), (10.1016/j.expneurol.2021.113652))
Fletcher, J. L., Dill, L. K., Wood, R. J., Wang, S., Robertson, K., Murray, S. S., Zamani, A. & Semple, B. D., Sep 2021, In: Experimental Neurology. 343, 2 p., 113790.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access -
Incidence of post-traumatic epilepsy following paediatric traumatic brain injury: Protocol for systematic review and meta-analysis
Mariajoseph, F. P., Rewell, S., O'Brien, T., Semple, B. & Antonic-Baker, A., 2 Nov 2021, In: BMJ Open. 11, 11, 4 p., e054034.Research output: Contribution to journal › Review Article › Other › peer-review
Open Access
Prizes
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Advancing Women's Research Success Grant
Semple, Bridgette (Recipient), 2018
Prize: Prize (including medals and awards)