Projects per year
Personal profile
Biography
Brian Lithgow has been interested in vestibular and auditory electro neurophysiology, signal processing, and the development of diagnostics throughout his career. He has researched: -
• Models of Anesthesia delivery.
• Models for electrical and audio stimulation of the cochlea consequent to high pulse rate electrical stimulation of the cochlea and modiolar stimulation.
• Signal processing algorithms for auditory prosthesis.
• Speech Processing and speaker identification-- improvements to and development of algorithms using optimization techniques and wavelet techniques (1 patent).
• Signal processing algorithms for vestibular diagnostics (Vertiginous Disorders, Meniere ’s disease, BPPV).
• Recent. Diagnostic development for neurological and neurodegenerative disorders Dementia and dementia type separation, Parkinson’s Disease, Schizophrenia, Meniere’s Disease, Bipolar disorder and Major Depressive disorder (3 patents).
• In Australia, this work extended into: mTBI and separating unipolar and bipolar depression; The successful separation of unipolar and bipolar depression is a world first.
• In Canada this work extended into: separating Meniere ’s disease from other vertiginous disorders; separating Dementia types; as well as the identification and monitoring of PostConcussion Syndrome. An animal study looking at vestibular ECOG and EVestG measures is currently underway at Health Sciences Center Winnipeg.
• Modelling of vestibular electro neurophysiology and dynamic vestibular responses.
He founded the Monash University Centre for Biomedical Engineering (MUCBE) and was the Director of Teaching for MUCBE from 2001-2010. He is also currently the Leader of the Diagnostic and Neurosignal Processing Research Groups at the Alfred Hospital (Melbourne Australia) and Riverview Health Centre, Winnipeg Canada. He is also a Senior Research Fellow at the Alfred Hospital wherein there was a fully equipped research laboratory “The Diagnostic and Neurosignal Processing Research Laboratory”. Lastly, he is an Adjunct Professor at the University of Manitoba Canada where he has established in collaboration with Prof Zahra Moussavi a second Diagnostic and Neurosignal Processing Research Laboratory at the Riverview Health Centre campus. A third collaborative laboratory is being established at Laval University.
Brian retired from Monash University in 2011 to undertake research full time and advance his vestibular diagnostic technology (Electrovestibulography--EVestG). As the inventor of EVestG, he has been funded as a consultant and Head of Research for NeuralDX Pty. Ltd (Australia and Canada). Previously he held competitive government grants from the ARC and NHMRC in Australia as well as attracted major Industrial support. He is currently the industrial collaborator (and co-supervisor of PhD students) for several MITACS funding in Canada with Prof. Moussavi.. Recently as part of this collaboration (and as a PI) they were awarded ca$240k forTBI studies using EVestG. He has agreed to act as site co-ordinator (Melbourne Australia, Winnipeg and Montreal) for the Weston ca$1.6M funded clinical trial of the effects of rTMS on AD patients.
Other Previous industry/academic/research positions include: -
1. Chief Electronic Design Engineer at Hudson-Allen Ltd.--DSP encryption
2. Deputy Head and acting Director of Biomedical Engineering at the Alfred Hospital.
3. Lecturer (Biophysics) Swinburne University
4. Weapons Electronic Engineering Officer-Royal Australian Navy
Over the past few years his Neurodiagnostic research has attracted two ARC linkage grants (>$350,000), one NHMRC grant ($116,000), 5 funded scholarships, Monash University commercialization funding exceeding $100,000, industry cash funding exceeding $220,000 and one ARC small grant ($12,000). A Government Comet grant for commercializing this research has been recently awarded for $76,000. Three international and one PCT Patents have been generated/applied for and two companies formed to commercialize his neuro-diagnostics research. Approximately $6M has been spent towards advancing his EVestG research. Most recently, MITACS-Cluster Accelerate MPI partnership, “Concussion Treatment and Monitoring“, (PI with Z.Moussavi, 2015) ca$240,000. In 2017 a CRC-P $2.2M Australian Government was awarded for mTBI EVestG and MRI research.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Senior Research Fellow, Alfred Hospital
Consultant Head of Research, Neural Diagnostics Pty. Ltd
Research Affiliate, Riverview Health Center
Adjunct Professor, University of Manitoba
Research area keywords
- Electrovestibulography
- Diagnosis of Neurological Disorders
- Diagnosis of Psychiatric Disorders
- Electroneurophysiology
Network
Projects
- 1 Finished
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Repeated transcranial magnetic stimulation for improving cognition in patients with Alzheimer disease: Protocol for a randomized, double-blind, placebo-controlled trial
Moussavi, Z., Rutherford, G., Lithgow, B., Millikin, C., Modirrousta, M., Mansouri, B., Wang, X., Omelan, C., Fellows, L., Fitzgerald, P. & Koski, L., Jan 2021, In: JMIR Research Protocols. 10, 1, 12 p., e25144.Research output: Contribution to journal › Article › Other › peer-review
Open Access9 Citations (Scopus) -
Bipolar disorder in the balance
Lithgow, B. J., Moussavi, Z., Gurvich, C., Kulkarni, J., Maller, J. J. & Fitzgerald, P. B., 1 Oct 2019, In: European Archives of Psychiatry and Clinical Neuroscience. 269, 7, p. 761–775 15 p.Research output: Contribution to journal › Article › Research › peer-review
15 Citations (Scopus) -
Quantitative separation of the depressive phase of bipolar disorder and major depressive disorder using electrovestibulography
Lithgow, B. J., Moussavi, Z. & Fitzgerald, P. B., 26 Nov 2019, In: The World Journal of Biological Psychiatry. 20, 10, p. 799-812 14 p.Research output: Contribution to journal › Article › Research › peer-review
9 Citations (Scopus) -
Application of Vestibular Spontaneous Response as a Diagnostic Aid for Meniere’s Disease
Dastgheib, Z. A., Lithgow, B., Blakely, B. & Moussavi, Z., 1 May 2016, In: Annals of Biomedical Engineering. 44, 5, p. 1672-1684 13 p.Research output: Contribution to journal › Article › Research › peer-review
6 Citations (Scopus) -
Investigation of a new weighted averaging method to improve SNR of electrocochleography recordings
Kumaragamage, C. L., Lithgow, B. J. & Moussavi, Z. K., 1 Feb 2016, In: IEEE Transactions on Biomedical Engineering. 63, 2, p. 340-347 8 p., 7160686.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus)
Activities
- 3 Patents
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NeuralDx Ltd (External organisation)
Brian Lithgow (Inventor)
6 Aug 2019Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent
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MONASH UNIVERSITY (Organisational unit)
Brian Lithgow (Inventor)
24 Jun 2009Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent
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MONASH UNIVERSITY (Organisational unit)
Brian Lithgow (Inventor)
31 May 2007Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent