Research Output per year
Research Output 1998 2019
- 1 - 50 out of 71 results
- Publication Year, Title (descending)
2019
ADAM17: An emerging therapeutic target for lung cancer
Saad, M. I., Rose-John, S. & Jenkins, B. J., 21 Aug 2019, In : Cancers. 11, 9, 28 p., 1218.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer
Saad, M. I., Alhayyani, S., McLeod, L., Yu, L., Alanazi, M., Deswaerte, V., Tang, K., Jarde, T., Smith, J. A., Prodanovic, Z., Tate, M. D., Balic, J. J., Watkins, D. N., Cain, J. E., Bozinovski, S., Algar, E., Kohmoto, T., Ebi, H., Ferlin, W., Garbers, C. & 4 others, , Apr 2019, In : EMBO Molecular Medicine. 11, 4, 19 p., e9976.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Interleukin 1 Up-regulates MicroRNA 135b to Promote Inflammation-Associated Gastric Carcinogenesis in Mice
Han, T. S., Voon, D. C. C., Oshima, H., Nakayama, M., Echizen, K., Sakai, E., Yong, Z. W. E., Murakami, K., Yu, L., Minamoto, T., Ock, C. Y., Jenkins, B. J., Kim, S. J., Yang, H. K. & Oshima, M., 1 Mar 2019, In : Gastroenterology. 156, 4, p. 1140-1155.e4 20 p.Research output: Contribution to journal › Article › Research › peer-review
Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2
Liu, Y. D., Yu, L., Ying, L., Balic, J., Gao, H., Deng, N. T., West, A., Yan, F., Ji, C. B., Gough, D., Tan, P., Jenkins, B. J. & Li, J. K., 15 Jun 2019, In : International Journal of Cancer. 144, 12, p. 3056-3069 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
2018
Clinical utility of a STAT3-regulated miRNA-200 family signature with prognostic potential in early gastric cancer
Yu, L., Wu, D., Gao, H., Balic, J. J., Tsykin, A., Han, T. S., Liu, Y. D., Kennedy, C. L., Li, J. K., Mao, J. Q., Tan, P., Oshima, M., Goodall, G. J. & Jenkins, B. J., 15 Mar 2018, In : Clinical Cancer Research. 24, 6, p. 1459-1472 14 p.Research output: Contribution to journal › Article › Research › peer-review
Helicobacter pylori type IV secretion system and its adhesin subunit, CagL, mediate potent inflammatory responses in primary human endothelial cells
Tafreshi, M., Guan, J., Gorrell, R. J., Chew, N., Xin, V., Deswaerte, V., Rohde, M., Daly, R. J., Peek Jr, R. M., Jenkins, B. J., Davies, E. M. & Kwok, T., 6 Feb 2018, In : Frontiers in Cellular and Infection Microbiology. 8, FEB, 15 p., 22.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development
Hill, D. G., Yu, L., Gao, H., Balic, J. J., West, A., Oshima, H., McLeod, L., Oshima, M., Gallimore, A., D'Costa, K., Bhathal, P. S., Sievert, W., Ferrero, R. L., Jenkins, B. J. & Jones, G. W., 1 Jul 2018, In : International Journal of Cancer. 143, 1, p. 167-178 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Immuno-detection of immature and bioactive forms of the inflammatory cytokine IL-18
Jenkins, B. J. & Deswaerte, V., 1 Jan 2018, Inflammation and Cancer: Methods and Protocols. Jenkins, B. J. (ed.). New York, NY: Humana Press, p. 229-235 7 p. (Methods in Molecular Biology; vol. 1725).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
Inflammasome adaptor ASC suppresses apoptosis of gastric cancer cells by an IL18-mediated inflammation-independent mechanism
Deswaerte, V., Nguyen, P., West, A., Browning, A. F., Yu, L., Ruwanpura, S. M., Balic, J., Livis, T., Girard, C., Preaudet, A., Oshima, H., Fung, K. Y., Tye, H., Najdovska, M., Ernst, M., Oshima, M., Gabay, C., Putoczki, T. & Jenkins, B. J., 1 Mar 2018, In : Cancer Research. 78, 5, p. 1293-1307 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer
Jones, S. A. & Jenkins, B. J., 1 Dec 2018, In : Nature Reviews Immunology. 18, 12, p. 773-789 17 p.Research output: Contribution to journal › Review Article › Research › peer-review
Reviewing the utility of EUS FNA to advance precision medicine in pancreatic cancer
Berry, W., Lundy, J., Croagh, D. & Jenkins, B. J., 1 Feb 2018, In : Cancers. 10, 2, 15 p., 35.Research output: Contribution to journal › Review Article › Other › peer-review
Open Access
2017
Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma
Miller, A., McLeod, L., Alhayyani, S., Szczepny, A., Watkins, D. N., Chen, W., Enriori, P., Ferlin, W., Ruwanpura, S. & Jenkins, B. J., 25 May 2017, In : Oncogene. 36, 21, p. 3059-3066 8 p.Research output: Contribution to journal › Article › Research › peer-review
Endoscopic ultrasound-guided fine-needle aspirate-derived preclinical pancreatic cancer models reveal panitumumab sensitivity in KRAS wild-type tumors
Berry, W., Algar, E., Kumar, B., Desmond, C., Swan, M., Jenkins, B. J. & Croagh, D., 15 May 2017, In : International Journal of Cancer. 140, 10, p. 2331-2343 13 p.Research output: Contribution to journal › Article › Research › peer-review
Identification of a TLR2-regulated gene signature associated with tumor cell growth in gastric cancer
West, AC., Tang, K., Tye, H., Yu, L., Deng, N., Najdovska, M., Lin, S. J., Balic, JJ., Okochi-Takada, E., McGuirk, P., Keogh, B., McCormack, W., Bhathal, P. S., Reilly, M., Oshima, M., Ushijima, T., Tan, P. & Jenkins, B. J., 7 Sep 2017, In : Oncogene. 36, 36, p. 5134-5144 11 p.Research output: Contribution to journal › Article › Research › peer-review
Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling
Balic, J. J., Garbers, C., Rose-John, S., Yu, L. & Jenkins, B. J., 1 Apr 2017, In : Cytokine. 92, p. 118-123 6 p.Research output: Contribution to journal › Article › Research › peer-review
In vivo evidence that RBM5 is a tumour suppressor in the lung
Jamsai, D., Watkins, D. N., O'Connor, A. E., Merriner, D. J., Gursoy, S., Bird, A. D., Kumar, B., Miller, A., Cole, T. J., Jenkins, B. J. & O'Bryan, M. K., 1 Dec 2017, In : Scientific Reports. 7, 1, 8 p., 15874.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Potential efficacy of interleukin-1β inhibition in lung cancer
Jenkins, B. J., 21 Oct 2017, In : The Lancet. 390, 10105, p. 1813-1814 2 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access
File
TLR agonists as adjuvants for cancer vaccines
Li, J. K., Balic, J. J., Yu, L. & Jenkins, B., 2017, Advances in Experimental Medicine and Biology. Cohen, I. R., Lajtha, A., Lambris, J. D. & Paoletti, R. (eds.). Gateway East Singapore: Springer, Vol. 1024. p. 195-212 18 p. (Advances in Experimental Medicine and Biology; vol. 1024).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
Open Access
File
Transcriptional regulation of inflammasome-associated pattern recognition receptors, and the relevance to disease pathogenesis
Deswaerte, V., Ruwanpura, S. M. & Jenkins, B. J., 1 Jun 2017, In : Molecular Immunology. 86, p. 3-9 7 p.Research output: Contribution to journal › Article › Research › peer-review
2016
IL6 trans-signaling promotes KRAS-driven lung carcinogenesis
Brooks, G. D., McLeod, L., Alhayyani, S., Miller, A., Russell, P. A., Ferlin, W., Rose-John, S., Ruwanpura, S. & Jenkins, B. J., 15 Feb 2016, In : Cancer Research. 76, 4, p. 866-876 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
Investigating the role of Toll-like receptors in mouse models of gastric cancer
West, A. C. & Jenkins, B. J., 2016, Methods in Molecular Biology. Humana Press, Vol. 1390. p. 427-449 23 p. (Methods in Molecular Biology; vol. 1390).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
Multifaceted Role of IRAK-M in the Promotion of Colon Carcinogenesis via Barrier Dysfunction and STAT3 Oncoprotein Stabilization in Tumors
Jenkins, B. J., 9 May 2016, In : Cancer Cell. 29, 5, p. 615-617 3 p.Research output: Contribution to journal › Short Survey › Other › peer-review
Murine oncostatin m acts via leukemia inhibitory factor receptor to phosphorylate signal transducer and activator of transcription 3 (STAT3) but not STAT1, an effect that protects bone mass
Walker, E. C., Johnson, R. W., Hu, Y., Brennan, H. J., Poulton, I. J., Zhang, J. G., Jenkins, B. J., Smyth, G. K., Nicola, N. A. & Sims, N. A., 7 Oct 2016, In : Journal of Biological Chemistry. 291, 41, p. 21703-21716 14 p.Research output: Contribution to journal › Article › Research › peer-review
Myeloid differentiation factor 88 signaling in bone marrow-derived cells promotes gastric tumorigenesis by generation of inflammatory microenvironment
Maeda, Y., Echizen, K., Oshima, H., Yu, L., Sakulsak, N., Hirose, O., Yamada, Y., Taniguchi, T., Jenkins, B. J., Saya, H. & Oshima, M., 1 Mar 2016, In : Cancer Prevention Research. 9, 3, p. 253-263 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
Therapeutic targeting of the IL-6 trans-signaling/mechanistic target of rapamycin complex 1 axis in pulmonary emphysema
Ruwanpura, S. M., McLeod, L., Dousha, L. F., Seow, H. J., Alhayyani, S., Tate, M. D., Deswaerte, V., Brooks, G. D., Bozinovski, S., MacDonald, M., Garbers, C., King, P. T., Bardin, P. G., Vlahos, R., Rose-John, S., Anderson, G. P. & Jenkins, B. J., 15 Dec 2016, In : American Journal of Respiratory and Critical Care Medicine. 194, 12, p. 1494-1505 12 p.Research output: Contribution to journal › Article › Research › peer-review
File
2015
Cytokine Receptors and Their Ligands
Dhagat, U., Nero, T. L., Kan, W. L., Hercus, T. R., Broughton, S. E., De Weerd, N. A., Jenkins, B. J., Mansell, A., Guthridge, M. A., Hertzog, P. J., Lopez, A. F. & Parker, M. W., 1 Jan 2015, Encyclopedia of Cell Biology: Functional Cell Biology. Bradshaw, R. A. & Stahl, P. D. (eds.). Waltham MA USA: Elsevier, Vol. 3. p. 22-36 15 p.Research output: Chapter in Book/Report/Conference proceeding › Encyclopaedia / Dictionary Entry › Other › peer-review
Differential involvement of gp130 signalling pathways in modulating tobacco carcinogen-induced lung tumourigenesis
Miller, A., Brooks, G. D. C., McLeod, L., Ruwanpura, S. M. & Jenkins, B. J., 19 Mar 2015, In : Oncogene. 34, 12, p. 1510 - 1519 10 p.Research output: Contribution to journal › Article › Research › peer-review
File
Imbalanced gp130 signalling in ApoE-deficient mice protects against atherosclerosis
Jones, G. W., McLeod, L., Kennedy, C. L., Bozinovski, S., Najdovska, M. & Jenkins, B. J., 2015, In : Atherosclerosis. 238, 2, p. 321 - 328 8 p.Research output: Contribution to journal › Article › Research › peer-review
Inflammatory and non-inflammatory roles for toll-like receptors in gastrointestinal cancer
West, A. C. & Jenkins, B. J., 2015, In : Current Pharmaceutical Design. 21, 21, p. 2968 - 2977 10 p.Research output: Contribution to journal › Article › Research › peer-review
File
Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette- smoke-induced lung inflammation in mice
Bozinovski, S., Seow, H. J., Chan, S. P. J., Anthony, D. A., McQualter, J. L., Hansen, M. J., Jenkins, B. J., Anderson, G. & Vlahos, R., 2015, In : Clinical Science. 129, 9, p. 785 - 796 12 p.Research output: Contribution to journal › Article › Research › peer-review
Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis
Jones, G. W., Bombardieri, M., Greenhill, C. J., McLeod, L., Nerviani, A., Rocher-Ros, V., Cardus, A., Williams, A. S., Pitzalis, C., Jenkins, B. J. & Jones, S. A., 2015, In : Journal of Experimental Medicine. 212, 11, p. 1793 - 1802 10 p.Research output: Contribution to journal › Article › Research › peer-review
2014
Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis
Kennedy, C. L., Najdovska, M., Tye, Y. M. H., McLeod, L., Yu, L., Jarnicki, A. G., Bhathal, P. S., Putoczki, T. L., Ernst, M. R. & Jenkins, B. J., 2014, In : Oncogene. 33, 19, p. 2540 - 2546 7 p.Research output: Contribution to journal › Article › Research › peer-review
IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice
Ruwanpura, S. M., McLeod, L., Brooks, G. D. C., Bozinovski, S., Vlahos, R., Longano, A., Bardin, P. G., Anderson, G. & Jenkins, B. J., 2014, In : Respirology. 19, 3, p. 419 - 427 9 p.Research output: Contribution to journal › Article › Research › peer-review
Inflammation and gastrointestinal cancer: an overview
Marusawa, H. & Jenkins, B. J., 2014, In : Cancer Letters. 345, 2, p. 153 - 156 4 p.Research output: Contribution to journal › Article › Research › peer-review
Interleukin-6 signaling drives fibrosis in unresolved inflammation
Fielding, C. A., Jones, G. W., McLoughlin, R. M., McLeod, L., Hammond, V. J., Uceda, J., Williams, A. S., Lambie, M., Foster, T. L., Liao, C-T., Rice, C. M., Greenhill, C. J., Colmont, C. S., Hams, E., Coles, B., Kift-Morgan, A., Newton, Z., Craig, K. J., Williams, J. D., Williams, G. T. & 7 others, , 2014, In : Immunity. 40, 1, p. 40 - 50 11 p.Research output: Contribution to journal › Article › Research › peer-review
Rab8a interacts directly with PI3Kgamma to modulate TLR4-driven PI3K and mTOR signalling
Luo, L., Wall, A. A., Yeo, J. C., Condon, N. D., Norwood, S. J., Schoenwaelder, S. M., Chen, K. W., Jackson, S., Jenkins, B. J., Hartland, E. L., Schroder, K., Collins, B. M., Sweet, M. J. & Stow, J. L., 2014, In : Nature Communications. 5, (Art. No.:4407), p. 1 - 13 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
STAT1 plays a role in TLR signal transduction and inflammatory responses
Luu, K., Greenhill, C. J., Majoros, A., Decker, T., Jenkins, B. J. & Mansell, A. S., 2014, In : Immunology and Cell Biology. 92, 9, p. 761 - 769 9 p.Research output: Contribution to journal › Article › Research › peer-review
Transcriptional regulation of pattern recognition receptors by Jak/STAT signaling, and the implications for disease pathogenesis
Jenkins, B. J., 2014, In : Journal of Interferon and Cytokine Research. 34, 10, p. 750 - 758 9 p.Research output: Contribution to journal › Article › Research › peer-review
2013
Critical and independent role for SOCS3 in either myeloid or T cells in resistance to Mycobacterium tuberculosis
Carow, B., Reuschl, A-K., Gavier-Widen, D., Jenkins, B. J., Ernst, M. R., Yoshimura, A., Chambers, B. J. & Rottenberg, M. E., 2013, In : PLoS Pathogens. 9, 7, 20 p., e1003442.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Dangerous liaisons between interleukin-6 cytokine and toll-like receptor families: a potent combination in inflammation and cancer
Mansell, A. S. & Jenkins, B. J., 2013, In : Cytokine and Growth Factor Reviews. 24, 3, p. 249 - 256 8 p.Research output: Contribution to journal › Article › Research › peer-review
File
Exacerbated inflammatory arthritis in response to hyperactive gp130 signalling is independent of IL-17A
Jones, G., Greenhill, C. J., Williams, J. O., Nowell, M. A., Williams, A. S., Jenkins, B. J. & Jones, S. A., 2013, In : Annals of the Rheumatic Diseases. 72, 10, p. 1738 - 1742 5 p.Research output: Contribution to journal › Article › Research › peer-review
Non-essential role for TLR2 and its signaling adaptor Mal/TIRAP in preserving normal lung architecture in mice
Ruwanpura, S. M., McLeod, L., Lilja, A., Brooks, G. D. C., Dousha, L., Seow, H. J., Bozinovski, S., Vlahos, R., Hertzog, P. J., Anderson, G. & Jenkins, B. J., 2013, In : PLoS ONE. 8, 10, 9 p., e78095.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Nucleotide oligomerization domain 1 enhances IFN-gamma signaling in gastric epithelial cells during Helicobacter pylori infection and exacerbates disease severity
Allison, C. C., Ferrand, J. F. P., McLeod, L., Hassan, M., Kaparakis-Liaskos, M., Grubman, A., Bhathal, P. S., Dev, A. T., Sievert, W., Jenkins, B. J. & Ferrero, R. L., 2013, In : Journal of Immunology. 190, 7, p. 3706-3715 10 p.Research output: Contribution to journal › Article › Research › peer-review
Tying the knot between cytokine and toll-like receptor signaling in gastrointestinal tract cancers
Tye, Y. M. H. & Jenkins, B. J., 2013, In : Cancer Science. 104, 9, p. 1139 - 1145 7 p.Research output: Contribution to journal › Article › Research › peer-review
2012
Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice
Ruwanpura, S., McLeod, L., Miller, A., Jones, J., Vlahos, R., Ramm, G., Longano, A., Bardin, P., Bozinovski, S., Anderson, G. & Jenkins, B., 2012, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 32, 7, p. L627 - L639 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signaling
Greenhill, C. J., Gould, J. A., Ernst, M. R., Jarnicki, A. G., Hertzog, P. J., Mansell, A. S. & Jenkins, B. J., 2012, In : Immunology and Cell Biology. 90, 5, p. 559 - 563 5 p.Research output: Contribution to journal › Article › Research › peer-review
STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation
Tye, Y. M. H., Kennedy, C. L., Najdovska, M., McLeod, L., McCormack, W., Hughes, N. R., Dev, A. T., Sievert, W., Ooi, C. H., Ishikawa, T., Oshima, H., Bhathal, P. S., Parker, A. E., Oshima, M., Tan, P. & Jenkins, B. J., 2012, In : Cancer Cell. 22, 4, p. 466 - 478 13 p.Research output: Contribution to journal › Article › Research › peer-review
Toll-like receptor 2: therapeutic target for gastric carcinogenesis
McCormack, W., Oshima, M., Tan, P. & Jenkins, B. J., 2012, In : Oncotarget. 3, 11, p. 1260 - 1261 2 p.Research output: Contribution to journal › Letter › Other
Open Access
File
2011
IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3
Greenhill, C. J., Rose-John, S., Lissilaa, R., Ferlin, W., Ernst, M., Hertzog, P. J., Mansell, A. S. & Jenkins, B. J., 2011, In : Journal of Immunology. 186, 2, p. 1199 - 1208 10 p.Research output: Contribution to journal › Article › Research › peer-review
Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice
Ruwanpura, S., McLeod, L., Miller, A., Jones, J., Bozinovski, S., Vlahos, R., Ernst, M., Armes, J., Bardin, P., Anderson, G. & Jenkins, B., 2011, In : American Journal of Respiratory Cell and Molecular Biology. 45, 4, p. 720 - 730 11 p.Research output: Contribution to journal › Article › Research › peer-review