Projects per year
Personal profile
Biography
Professor Brendan Jenkins
Head - Cancer and Immune Signalling Laboratory
Centre for Innate Immunity and Infectious Diseases
NHMRC Senior Research Fellow
Brendan is Head of the Cancer and Immune Signalling Laboratory in the Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, and currently holds a prestigious NHMRC Senior Research Fellowship. His research laboratory has a strong focus on cancer (stomach, lung, pancreatic) and immune-related diseases (emphysema/COPD, arthritis, peritonitis).
Prof Brendan Jenkins is a current NHMRC Senior Research Fellow and prior to this he was holder of an NHMRC RD Wright Postdoctoral Research Fellowship, a Monash University Fellowship, and most recently a prestigious Sylvia and Charles Viertel Senior Medical Research Fellowship.
Over the last 15 years he has been at the forefront of research to examine the roles cytokines play in human disease, in particular cancer of the stomach (gastric cancer) which is the second most lethal cancer world-wide, and chronic inflammation. Since being recruited to the Hudson Institute, he further expanded his research to also include cancers of the lung (most common and lethal cancer in the world) and pancreas (worst survival rates worldwide), as well as the debilitating lung disease emphysema/chronic obstructive pulmonary disease (COPD). Collectively, his research programs incorporate long standing collaborations with basic scientific researchers, industry and clinicians both nationwide and overseas (UK, Japan, Singapore, Europe). Amongst his scientific achievements are publications in the highest ranking science and medical research journals including Cancer Cell, Nature, Nature Medicine, Immunity, Journal of Clinical Investigation, Journal of Experimental Medicine, Cancer Research, Oncogene, and Journal of Immunology.
In recognition of his group's research achievements, he has received numerous national and international awards, including the Australian Institute for Policy and Science Tall Poppy Award. He is a holder of multiple project grants within Australia (NHMRC, Cancer Council) and overseas (Association for International Cancer Research), and is a regular invited speaker at local and international scientific meetings.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, PhD, University of Adelaide
Research area keywords
- Animal Disease Models
- Cancer
- Cytokine Signal Transduction
- Emphysema
- Gastric (Stomach) Cancer
- Inflammation
- Inflammatory diseases
- Interleukin (Il)-6 Family Cytokines
- Lung Cancer
- Pattern Recognition Receptors
- Pancreatic Cancer
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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SII small animal optical imaging system AmiHTX
Hartland, E., Hertzog, P. & Jenkins, B.
1/10/21 → 31/12/22
Project: Research
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Accelerating the uptake of precision medicine in pancreatic cancer using endoscopic ultrasound biopsy.
Croagh, D., Goldstein, D., Jenkins, B., Nguyen, N., Devereaux, B., Kaffes, A., Ragunath, K., Lundy, J., Fanning, S., Rathi, V. & Gao, H. Y.
28/07/21 → 30/06/23
Project: Research
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Using next generation sequencing technology to improve the diagnosis of pancreatic cancer
Croagh, D., Southey, M., Jenkins, B., Segelov, E., Rathi, V., Holt, B. A., Pilgrim, C., Bhutani, M. & Tagkalidis, P.
15/02/19 → 14/02/23
Project: Research
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Targeting key regulators of innate immunity in inflammation-associated cancer
1/01/19 → 31/12/23
Project: Research
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Understanding how the Helicobacter pylori pilin protein CagL promotes gastric cancer
Kwok-Schuelein, T., Jenkins, B., Peek Jr, R. M. & Marshall, B. J.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/18 → 31/12/22
Project: Research
Research output
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ADAM17 deficiency protects against pulmonary emphysema
Saad, M. I., McLeod, L., Hodges, C., Vlahos, R., Rose-John, S., Ruwanpura, S. & Jenkins, B. J., Feb 2021, In: American Journal of Respiratory Cell and Molecular Biology. 64, 2, p. 183-195 13 p.Research output: Contribution to journal › Article › Research › peer-review
8 Citations (Scopus) -
A Method for the Establishment of Human Lung Adenocarcinoma Patient-Derived Xenografts in Mice
Lundy, J., Jenkins, B. J. & Saad, M. I., 2021, Methods in Molecular Biology. Santiago-Cardona, P. G. (ed.). New York NY USA: Humana Press, p. 165-173 9 p. (Methods in Molecular Biology; vol. 2279).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
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Aspirin-triggered resolvin d1 reduces proliferation and the neutrophil to lymphocyte ratio in a mutant kras-driven lung adenocarcinoma model
Vannitamby, A., Saad, M. I., Aloe, C., Wang, H., Kumar, B., Vlahos, R., Selemidis, S., Irving, L., Steinfort, D., Jenkins, B. J. & Bozinovski, S., 1 Jul 2021, In: Cancers. 13, 13, 16 p., 3224.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
IL-6 family cytokines in respiratory health and disease
Dawson, R. E., Jenkins, B. J. & Saad, M. I., Jul 2021, In: Cytokine. 143, 10 p., 155520.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
TLR2 activation promotes tumour growth and associates with patient survival and chemotherapy response in pancreatic ductal adenocarcinoma
Lundy, J., Gearing, L. J., Gao, H., West, A. C., McLeod, L., Deswaerte, V., Yu, L., Porazinski, S., Pajic, M., Hertzog, P. J., Croagh, D. & Jenkins, B. J., 14 Oct 2021, In: Oncogene. 40, 41, p. 6007–6022 16 p.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus)