Bradley Doak

Research Fellow, Medicinal Chemistry

Emailbradley.doak@monash.edu

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1 Active

Developing new tools for chemical biology
Scanlon, M., Porter, C., Halls, M. & Doak, B.
1/01/20 → 31/12/22
Project: Research

14 Article
4 Review Article
2 Chapter (Book)

NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide–dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei
Nebl, S., Alwan, W. S., Williams, M. L., Sharma, G., Taylor, A., Doak, B. C., Wilde, K. L., McMahon, R. M., Halili, M. A., Martin, J. L., Capuano, B., Fenwick, R. B., Mohanty, B. & Scanlon, M. J., 6 Aug 2020, In : Journal of Biomolecular NMR. 74, p. 595-611 17 p.
Research output: Contribution to journal › Article › Research › peer-review

1 Citation (Scopus)
Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiL_X)
Bentley, M. R., Ilyichova, O. V., Wang, G., Williams, M. L., Sharma, G., Alwan, W. S., Whitehouse, R. L., Mohanty, B., Scammells, P. J., Heras, B., Martin, J. L., Totsika, M., Capuano, B., Doak, B. C. & Scanlon, M. J., 9 Jul 2020, In : Journal of Medicinal Chemistry. 63, 13, p. 6863-6875 13 p.
Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)
A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists
Patil, R., Mohanty, B., Liu, B., Chandrashekaran, I. R., Headey, S. J., Williams, M. L., Clements, C. S., Ilyichova, O., Doak, B. C., Genissel, P., Weaver, R., Vuillard, L., Halls, M. L., Porter, C. J. H. & Scanlon, M. J., 8 Mar 2019, In : The Journal of Biological Chemistry. 294, 10, p. 3720-3734 15 p.
Research output: Contribution to journal › Article › Research › peer-review

5 Citations (Scopus)
Applications of NMR spectroscopy in FBDD
Bentley, M., Doak, B. C., Mohanty, B. & Scanlon, M. J., 13 Jun 2018, Modern Magnetic Resonance. Webb, G. A. (ed.). 2 ed. Cham Switzerland: Springer, p. 2211-2231 21 p.
Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

1 Citation (Scopus)
Cyclophilin Succumbs to a Macrocyclic Chameleon
Doak, B. C. & Kihlberg, J., 8 Nov 2018, In : Journal of Medicinal Chemistry. 61, 21, p. 9469-9472 4 p.
Research output: Contribution to journal › Review Article › Research › peer-review

Developing new tools for chemical biology

NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide–dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei

Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX)

A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists

Applications of NMR spectroscopy in FBDD

Cyclophilin Succumbs to a Macrocyclic Chameleon

Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiL_X)