Projects per year
Personal profile
Biography
Dr Brad Broughton has an emerging profile in both the national and international cardiovascular community. Brad is currently a Foundation for High Blood Pressure Research Fellow and is a senior member of the Vascular Biology and Immunopharmacology Group in the Department of Pharmacology. He is a member of two Editorial Boards (ISRN Stroke and Physiology Journal) and is a Chief Investigator on a NHMRC Project Grant and Grant-in-aid from the National Heart Foundation.
Over the past 12 years, Brad's research has contributed to our knowledge of reactive oxygen species, calcium, apoptosis, oestrogen, Rho kinase and nitric oxide signalling in the systemic, pulmonary and cerebral circulations. His studies have elucidated physiological mechanisms in vivo and in vitro, identified gender differences, as well as abnormalities in diseases including stroke, pulmonary hypertension and atherosclerosis. The primary focus of his current research is to advance our understanding of mechanisms that contribute to brain damage after stroke, develop safe and effective stroke therapies and identify novel imaging agents that detect cell loss in the brain following stroke.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Stroke
- Pulmonary Hypertension
- Stem cells
- Exosomes
Network
Projects
- 9 Finished
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Delivering a novel cell free therapy to improve stroke outcomes
Broughton, B., Lim, R. & Sobey, C. G.
1/01/21 → 31/12/22
Project: Research
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Development of a first-in-class neuroprotective drug for protecting the brain after stroke
King, G. F., Widdop, R., Broughton, B., Rash, L. D. & Smith, M. T.
1/01/19 → 31/12/21
Project: Research
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Where have all the stem cells gone? Preliminary in vivo MRI study to track iron-oxide nanoparticle-labelled stem cells
Lim, R., Jenkin, G., McDonald, C., Bhakoo, K., Sobey, C., Broughton, B., Sievert, W., Vreys, R. & Hodge, A.
Agilent Technologies (Australia), Monash University – Internal University Contribution
1/12/14 → 31/12/14
Project: Research
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Post-stroke administration of H2 relaxin reduces functional deficits, neuronal apoptosis and immune cell infiltration into the mouse brain
Truong, S. H. T., Bonnici, B., Rupasinghe, S., Kemp-Harper, B. K., Samuel, C. S. & Broughton, B. R. S., Jan 2023, In: Pharmacological Research. 187, 11 p., 106611.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Simultaneous late-gadolinium enhancement and T1 mapping of fibrosis and a novel cell-based combination therapy in hypertensive mice
Li, Y., Zheng, G., Salimova, E., Broughton, B. R. S., Ricardo, S. D., de Veer, M. & Samuel, C. S., Feb 2023, In: Biomedicine and Pharmacotherapy. 158, 19 p., 114069.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Content and delivery preferences for information to support the management of high blood pressure
Chapman, N., Marques, F. Z., Picone, D. S., Adji, A., Broughton, B. R. S., Dinh, Q. N., Gabb, G., Lambert, G. W., Mihailidou, A. S., Nelson, M. R., Stowasser, M., Schlaich, M., Schultz, M. G., Mynard, J. P. & Climie, R. E., 10 Aug 2022, (Accepted/In press) In: Journal of Human Hypertension. 5 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Gut Microbiota and Their Metabolites in Stroke: A Double-Edged Sword
Peh, A., O'Donnell, J. A., Broughton, B. R. S. & Marques, F. Z., 1 May 2022, In: Stroke. 53, 5, p. 1788-1801 14 p.Research output: Contribution to journal › Review Article › Research › peer-review
16 Citations (Scopus) -
Optimising the photothrombotic model of stroke in the C57BI/6 and FVB/N strains of mouse
Knezic, A., Broughton, B. R. S., Widdop, R. E. & McCarthy, C. A., Dec 2022, In: Scientific Reports. 12, 1, 11 p., 7598.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus)