Projects per year
Personal profile
Biography
Dr Brad Broughton has an emerging profile in both the national and international cardiovascular community. Brad is currently a Foundation for High Blood Pressure Research Fellow and is a senior member of the Vascular Biology and Immunopharmacology Group in the Department of Pharmacology. He is a member of two Editorial Boards (ISRN Stroke and Physiology Journal) and is a Chief Investigator on a NHMRC Project Grant and Grant-in-aid from the National Heart Foundation.
Over the past 12 years, Brad's research has contributed to our knowledge of reactive oxygen species, calcium, apoptosis, oestrogen, Rho kinase and nitric oxide signalling in the systemic, pulmonary and cerebral circulations. His studies have elucidated physiological mechanisms in vivo and in vitro, identified gender differences, as well as abnormalities in diseases including stroke, pulmonary hypertension and atherosclerosis. The primary focus of his current research is to advance our understanding of mechanisms that contribute to brain damage after stroke, develop safe and effective stroke therapies and identify novel imaging agents that detect cell loss in the brain following stroke.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Stroke
- Pulmonary Hypertension
- Stem cells
- Exosomes
Collaborations and top research areas from the last five years
Projects
- 9 Finished
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Delivering a novel cell free therapy to improve stroke outcomes
Broughton, B., Lim, R. & Sobey, C. G.
National Heart Foundation of Australia
1/01/21 → 31/12/22
Project: Research
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Development of a first-in-class neuroprotective drug for protecting the brain after stroke
King, G. F., Widdop, R., Broughton, B., Rash, L. D. & Smith, M. T.
1/01/19 → 31/12/21
Project: Research
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Where have all the stem cells gone? Preliminary in vivo MRI study to track iron-oxide nanoparticle-labelled stem cells
Lim, R., Jenkin, G., McDonald, C., Bhakoo, K., Sobey, C., Broughton, B., Sievert, W., Vreys, R. & Hodge, A.
Agilent Technologies (Australia), Monash University – Internal University Contribution
1/12/14 → 31/12/14
Project: Research
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How Does G Protein-Coupled Receptor 30 (GPR30) Affect Stroke Outcome?
1/01/12 → 31/12/13
Project: Research
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Content and delivery preferences for information to support the management of high blood pressure
Chapman, N., Marques, F. Z., Picone, D. S., Adji, A., Broughton, B. R. S., Dinh, Q. N., Gabb, G., Lambert, G. W., Mihailidou, A. S., Nelson, M. R., Stowasser, M., Schlaich, M., Schultz, M. G., Mynard, J. P. & Climie, R. E., Jan 2024, In: Journal of Human Hypertension. 38, 1, p. 70-74 5 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Hi1a Improves Sensorimotor Deficit following Endothelin-1-Induced Stroke in Rats but Does Not Improve Functional Outcomes following Filament-Induced Stroke in Mice
Knezic, A., Budusan, E., Saez, N. J., Broughton, B. R. S., Rash, L. D., King, G. F., Widdop, R. E. & McCarthy, C. A., 12 Apr 2024, In: ACS Pharmacology and Translational Science. 7, 4, p. 1043-1054 12 p.Research output: Contribution to journal › Article › Research › peer-review
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A switch in N-terminal capping of β-peptides creates novel self-assembled nanoparticles
Chen, Y. K., Simon, I. A., Maslov, I., Oyarce-Pino, I. E., Kulkarni, K., Hopper, D., Aguilar, M. I., Vankadari, N., Broughton, B. RS. & Del Borgo, M. P., 9 Oct 2023, In: RSC Advances. 13, 42, p. 29401-29407 7 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Platelet-targeted thrombolysis for treatment of acute ischemic stroke
Palazzolo, J. S., Ale, A., Ho, H., Jagdale, S., Broughton, B. R. S., Medcalf, R. L., Wright, D. K., Alt, K., Hagemeyer, C. E. & Niego, B., 28 Feb 2023, In: Blood Advances. 7, 4, p. 561-574 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Post-stroke administration of H2 relaxin reduces functional deficits, neuronal apoptosis and immune cell infiltration into the mouse brain
Truong, S. H. T., Bonnici, B., Rupasinghe, S., Kemp-Harper, B. K., Samuel, C. S. & Broughton, B. R. S., Jan 2023, In: Pharmacological Research. 187, 11 p., 106611.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus)