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Personal profile

Biography

Dr Brad Broughton has an emerging profile in both the national and international cardiovascular community. Brad is currently a Foundation for High Blood Pressure Research Fellow and is a senior member of the Vascular Biology and Immunopharmacology Group in the Department of Pharmacology. He is a member of two Editorial Boards (ISRN Stroke and Physiology Journal) and is a Chief Investigator on a NHMRC Project Grant and Grant-in-aid from the National Heart Foundation.

Over the past 12 years, Brad's research has contributed to our knowledge of reactive oxygen species, calcium, apoptosis, oestrogen, Rho kinase and nitric oxide signalling in the systemic, pulmonary and cerebral circulations. His studies have elucidated physiological mechanisms in vivo and in vitro, identified gender differences, as well as abnormalities in diseases including stroke, pulmonary hypertension and atherosclerosis. The primary focus of his current research is to advance our understanding of mechanisms that contribute to brain damage after stroke, develop safe and effective stroke therapies and identify novel imaging agents that detect cell loss in the brain following stroke.

Research area keywords

  • Stroke
  • Pulmonary Hypertension
  • Stem cells
  • Exosomes

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Projects 2008 2021

Research Output 2002 2019

Self-assembling injectable peptide hydrogels for emerging treatment of ischemic stroke

Hong, A., Aguilar, M-I., Del Borgo, M. P., Sobey, C. G., Broughton, B. R. S. & Forsythe, J. S., 2019, In : Journal of Materials Chemistry B. 7, 25, p. 3927-3943 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Actin polymerization contributes to enhanced pulmonary vasoconstrictor reactivity following chronic hypoxia

Weise-Cross, L., Sands, M. A., Sheak, J. R., Broughton, B. R. S., Snow, J. B., Gonzalez Bosc, L. V., Jernigan, N. L., Walker, B. R. & Resta, T. C., May 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 314, 5, p. H1011-H1021 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke

Evans, M. A., Lim, R., Kim, H. A., Chu, H. X., Gardiner-Mann, C. V., Taylor, K. W. E., Chan, C. T., Brait, V. H., Lee, S., Dinh, Q. N., Vinh, A., Phan, T. G., Srikanth, V. K., Ma, H., Arumugam, T. V., Fann, D. Y., Poh, L., Hunt, C. P. J., Pouton, C. W., Haynes, J. M. & 12 others, Selemidis, S., Kwan, W., Teo, L., Bourne, J. A., Neumann, S., Young, S., Gowing, E. K., Drummond, G. R., Clarkson, A. N., Wallace, E. M., Sobey, C. G. & Broughton, B. R. S., 1 Mar 2018, In : Stroke. 49, 3, p. 700-709 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Amnion epithelial cells - A novel therapy for ischemic stroke?

Evans, M. A., Broughton, B. R. S., Drummond, G. R., Ma, H., Phan, T. G., Wallace, E. M., Lim, R. & Sobey, C. G., 1 Aug 2018, In : Neural Regeneration Research. 13, 8, p. 1346-1349 4 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Diet-induced vitamin D deficiency has no effect on acute post-stroke outcomes in young male mice

Evans, M. A., Kim, H. A., De Silva, T. M., Arumugam, T. V., Clarkson, A. N., Drummond, G. R., Zosky, G. R., Broughton, B. R. S. & Sobey, C. G., 1 Nov 2018, In : Journal of Cerebral Blood Flow and Metabolism. 38, 11, p. 1968-1978 11 p.

Research output: Contribution to journalArticleResearchpeer-review