Brad Edwards – Research Output

2019

Sleeping Well Trial: Increasing the effectiveness of treatment with continuous positive airway pressure using a weight management program in overweight adults with obstructive sleep apnoea-A stepped wedge randomised trial protocol

Truby, H., Edwards, B. A., O'Driscoll, D. M., Young, A., Ghazi, L., Bristow, C., Roem, K., Bonham, M. P., Murgia, C., Day, K., Haines, T. P. & Hamilton, G. S., Feb 2019, In : Nutrition and Dietetics. 76, 1, p. 110-117 8 p.

Research output: Contribution to journal › Article › Other › peer-review

2018

A graphical method for comparing nocturnal oxygen saturation profiles in individuals and populations: Application to healthy infants and preterm neonates

Terrill, P. I., Dakin, C., Edwards, B. A., Wilson, S. J. & Maclean, J. E., May 2018, In : Pediatric Pulmonology. 53, 5, p. 645-655 11 p.

Research output: Contribution to journal › Article › Research › peer-review

Assessing ventilatory instability using the response to spontaneous sighs during sleep in preterm infants

Edwards, B. A., Nava-Guerra, L., Kemp, J. S., Carroll, J. L., Khoo, M. C., Sands, S. A., Terrill, P. I., Landry, S. A. & Amin, R. S., 1 Nov 2018, In : Sleep. 41, 11, 8 p., zsy161.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

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Identifying obstructive sleep apnoea patients responsive to supplemental oxygen therapy

Sands, S. A., Edwards, B. A., Terrill, P. I., Butler, J. P., Owens, R. L., Taranto-Montemurro, L., Azarbarzin, A., Marques, M., Hess, L. B., Smales, E. T., De Melo, C. M., White, D. P., Malhotra, A. & Wellman, A., 1 Sep 2018, In : The European respiratory journal. 52, 3, 12 p., 1800674.

Research output: Contribution to journal › Article › Research › peer-review

Measuring loop gain via home sleep testing in patients with obstructive sleep apnea

Orr, J. E., Sands, S. A., Edwards, B. A., Deyoung, P. N., Deacon, N., Jen, R., Li, Y., Owens, R. L. & Malhotra, A., 15 May 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 10, p. 1353-1355 3 p.

Research output: Contribution to journal › Letter › Research › peer-review

Phenotyping pharyngeal pathophysiology using polysomnography in patients with obstructive sleep apnea

Sands, S. A., Edwards, B. A., Terrill, P. I., Taranto-Montemurro, L., Azarbarzin, A., Marques, M., Hess, L. B., White, D. P. & Wellman, A., 1 May 2018, In : American Journal of Respiratory and Critical Care Medicine. 197, 9, p. 1187-1197 11 p.

Research output: Contribution to journal › Article › Research › peer-review

Prevalence, associated clinical features, and impact on continuous positive airway pressure use of a low respiratory arousal threshold among male United States veterans with obstructive sleep apnea

Zinchuk, A., Edwards, B. A., Jeon, S., Koo, B. B., Concato, J., Sands, S., Wellman, A. & Yaggi, H. K., 15 May 2018, In : Journal of Clinical Sleep Medicine. 14, 5, p. 809-817 9 p.

Research output: Contribution to journal › Article › Research › peer-review

Quantifying the arousal threshold using polysomnography in obstructive sleep apnea

Sands, S. A., Terrill, P. I., Edwards, B. A., Montemurro, L. T., Azarbarzin, A., Marques, M., De Melo, C. M., Loring, S. H., Butler, J. P., White, D. P. & Wellman, A., 1 Jan 2018, In : Sleep. 41, 1, 9 p., zsx183.

Research output: Contribution to journal › Article › Research › peer-review

Quantifying ventilatory control stability from spontaneous sigh responses during sleep: a comparison of two approaches

Nava-Guerra, L., Edwards, B. A., Terrill, P. I., Sands, S. A., Amin, R. S., Kemp, J. S. & Khoo, M. CK., 13 Nov 2018, In : Physiological Measurement. 39, 11, 14 p., 114005.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

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Sleep and respiratory disorders

Edwards, B. A. & Hamilton, G. S., 23 Aug 2018, Sleep, Health, and Society: From Aetiology to Public Health. Cappuccio, F. P., Miller, M. A., Lockley, S. W. & Rajaratnam, S. M. W. (eds.). 2nd ed. United Kingdom: Oxford University Press, p. 80-87 8 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

The effect of surgical weight loss on obstructive sleep apnoea: A systematic review and meta-analysis

Wong, A-M., Barnes, H. N., Joosten, S. A., Landry, S. A., Dabscheck, E., Mansfield, D. R., Dharmage, S. C., Senaratna, C. V., Edwards, B. A. & Hamilton, G. S., Dec 2018, In : Sleep Medicine Reviews. 42, p. 85-99 15 p.

Research output: Contribution to journal › Review Article › Research › peer-review

Ventilatory control sensitivity in patients with obstructive sleep apnea is sleep stage dependent

Landry, S. A., Andara, C., Terrill, P. I., Joosten, S. A., Leong, P., Mann, D. L., Sands, S. A., Hamilton, G. S. & Edwards, B. A., 1 May 2018, In : Sleep. 41, 5, 10 p., 040.

Research output: Contribution to journal › Article › Research › peer-review

2017

Differences in respiratory arousal threshold in Caucasian and Chinese patients with obstructive sleep apnoea

Lee, R. W. W., Sutherland, K., Sands, S. A., Edwards, B. A., Chan, T. O., S.S. Ng, S., Hui, D. S. C. & Cistulli, P. A., 1 Jul 2017, In : Respirology. 22, 5, p. 1015-1021 7 p.

Research output: Contribution to journal › Article › Research › peer-review

Dynamic loop gain increases upon adopting the supine body position during sleep in patients with obstructive sleep apnoea

Joosten, S. A., Landry, S. A., Sands, S. A., Terrill, P. I., Mann, D., Andara, C., Skuza, E., Turton, A., Berger, P., Hamilton, G. S. & Edwards, B. A., 1 Nov 2017, In : Respirology. 22, 8, p. 1662-1669 8 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Effect of 4-aminopyridine on genioglossus muscle activity during sleep in healthy adults

Taranto-Montemurro, L., Sands, S. A., Azarbarzin, A., Marques, M., De Melo, C. M., Edwards, B. A., Eckert, D. J., Messineo, L., White, D. P. & Wellman, A., 1 Jul 2017, In : Annals of the American Thoracic Society. 14, 7, p. 1177-1183 7 p.

Research output: Contribution to journal › Article › Research › peer-review

Effects of tiagabine on slow wave sleep and arousal threshold in patients with obstructive sleep apnea

Taranto-Montemurro, L., Sands, S. A., Edwards, B. A., Azarbarzin, A., Marques, M., De Melo, C., Eckert, D. J., White, D. P. & Wellman, A., 1 Feb 2017, In : Sleep. 40, 2, 7 p., zsw047.

Research output: Contribution to journal › Article › Research › peer-review

Estimation of pharyngeal collapsibility during sleep by peak inspiratory airflow

Azarbarzin, A., Sands, S. A., Taranto-Montemurro, L., Oliveira Marques, M. D., Genta, P. R., Edwards, B. A., Butler, J. P., White, D. P. & Wellman, A., 1 Jan 2017, In : Sleep. 40, 1, 11 p., zsw005.

Research output: Contribution to journal › Article › Research › peer-review

Improvement in obstructive sleep apnea with weight loss is dependent on body position during sleep

Joosten, S. A., Khoo, J. K., Edwards, B. A., Landry, S. A., Naughton, M. T., Dixon, J. B. & Hamilton, G. S., 1 May 2017, In : Sleep. 40, 5, 6 p., zsx047.

Research output: Contribution to journal › Article › Research › peer-review

Is the muscle the only potential target of desipramine in obstructive sleep apnea syndrome? Reply

Taranto-Montemurro, L., Sands, S. A., Edwards, B., Eckert, D. J., White, D. P. & Wellman, A., 15 Jun 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 12, p. 1678-1679 2 p.

Research output: Contribution to journal › Letter › Other › peer-review

Loop gain predicts the response to upper airway surgery in patients with obstructive sleep apnea

Joosten, S. A., Leong, P., Landry, S. A., Sands, S. A., Terrill, P. I., Mann, D. L., Turton, A., Rangaswamy, J., Andara, C., Burgess, G., Mansfield, D., Hamilton, G. S. & Edwards, B. A., 1 Jul 2017, In : Sleep. 40, 7, 10 p., zsx094.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Obstructive sleep apnoea pathogenesis from mild to severe: Is it all the same?

Edwards, B. A., Eckert, D. J. & Jordan, A. S., 1 Jan 2017, In : Respirology. 22, 1, p. 33-42 10 p.

Research output: Contribution to journal › Review Article › Research › peer-review

Oxygen desaturation index differs significantly between types of sleep software

Ng, Y., Joosten, S. A., Edwards, B. A., Turton, A., Romios, H., Samarasinghe, T., Landry, S., Mansfield, D. R. & Hamilton, G. S., 2017, In : Journal of Clinical Sleep Medicine. 13, 4, p. 599-605 7 p.

Research output: Contribution to journal › Article › Research › peer-review

Positional modification techniques for supine obstructive sleep apnea: A systematic review and meta-analysis

Barnes, H., Edwards, B. A., Joosten, S. A., Naughton, M. T., Hamilton, G. S. & Dabscheck, E., Dec 2017, In : Sleep Medicine Reviews. 36, p. 107-115 9 p.

Research output: Contribution to journal › Review Article › Research › peer-review

Resonance as the mechanism of daytime periodic breathing in patients with heart failure

Sands, S. A., Mebrate, Y., Edwards, B. A., Nemati, S., Manisty, C. H., Desai, A. S., Wellman, A., Willson, K., Francis, D. P., Butler, J. P. & Malhotra, A., 15 Jan 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 2, p. 237-246 10 p.

Research output: Contribution to journal › Article › Research › peer-review

Response to a combination of oxygen and a hypnotic as treatment for obstructive sleep apnoea is predicted by a patient's therapeutic CPAP requirement

Landry, S. A., Joosten, S. A., Sands, S. A., White, D. P., Malhotra, A., Wellman, A., Hamilton, G. S. & Edwards, B. A., Aug 2017, In : Respirology. 22, 6, p. 1219-1224 6 p.

Research output: Contribution to journal › Article › Research › peer-review

Therapeutic CPAP level predicts upper airway collapsibility in patients with obstructive sleep apnea

Landry, S. A., Joosten, S. A., Eckert, D. J., Jordan, A. S., Sands, S. A., White, D. P., Malhotra, A., Wellman, A., Hamilton, G. S. & Edwards, B. A., 1 Jun 2017, In : Sleep. 40, 6, 8 p., zsx056.

Research output: Contribution to journal › Article › Research › peer-review

The relationship between partial upper-airway obstruction and inter-breath transition period during sleep

Mann, D. L., Edwards, B. A., Joosten, S. A., Hamilton, G. S., Landry, S., Sands, S. A., Wilson, S. J. & Terrill, P. I., 1 Oct 2017, In : Respiratory Physiology and Neurobiology. 244, p. 32-40 9 p.

Research output: Contribution to journal › Article › Research › peer-review

2016

Control theory prediction of resolved Cheyne-Stokes respiration in heart failure

Sands, S. A., Edwards, B. A., Kee, K., Stuart-Andrews, C., Skuza, E. M., Roebuck, T., Turton, A., Hamilton, G. S., Naughton, M. T. & Berger, P. J., 1 Nov 2016, In : European Respiratory Journal. 48, 5, p. 1351-1359 9 p.

Research output: Contribution to journal › Article › Research › peer-review

Desipramine improves upper airway collapsibility and reduces OSA severity in patients with minimal muscle compensation

Taranto-Montemurro, L., Sands, S. A., Edwards, B. A., Azarbarzin, A., Marques, M., De Melo, C., Eckert, D. J., White, D. P. & Wellman, A., 1 Nov 2016, In : European Respiratory Journal. 48, 5, p. 1340-1350 11 p.

Research output: Contribution to journal › Article › Research › peer-review

Desipramine increases genioglossus activity and reduces upper airway collapsibility during non-REM sleep in healthy subjects

Taranto-Montemurro, L., Edwards, B. A., Sands, S. A., Marques, M., Eckert, D. J., White, D. P. & Wellman, A., 1 Oct 2016, In : American Journal of Respiratory and Critical Care Medicine. 194, 7, p. 878-885 8 p.

Research output: Contribution to journal › Article › Research › peer-review

Oronasal masks require a higher pressure than nasal and nasal pillow masks for the treatment of obstructive sleep apnea

Deshpande, S., Joosten, S., Turton, A., Edwards, B. A., Landry, S., Mansfield, D. R. & Hamilton, G. S., 2016, In : Journal of Clinical Sleep Medicine. 12, 9, p. 1263-1268 6 p.

Research output: Contribution to journal › Article › Research › peer-review

Personalized Medicine for Obstructive Sleep Apnea Therapies: Are We There Yet?

Edwards, B. A., Landry, S., Joosten, S. A. & Hamilton, G. S., 1 Sep 2016, In : Sleep Medicine Clinics. 11, 3, p. 299-311 13 p.

Research output: Contribution to journal › Review Article › Research › peer-review

The combination of supplemental oxygen and a hypnotic markedly improves obstructive sleep apnea in patients with a mild to moderate upper airway collapsibility

Edwards, B. A., Sands, S. A., Owens, R. L., Eckert, D. J., Landry, S., White, D. P., Malhotra, A. & Wellman, A., 1 Nov 2016, In : Sleep. 39, 11, p. 1973-1983 11 p.

Research output: Contribution to journal › Article › Research › peer-review

Tube law of the pharyngeal airway in sleeping patients with obstructive sleep apnea

Genta, P. R., Edwards, B. A., Sands, S. A., Owens, R. L., Butler, J. P., Loring, S. H., White, D. P. & Wellman, A., 1 Feb 2016, In : Sleep. 39, 2, p. 337-343 7 p.

Research output: Contribution to journal › Article › Research › peer-review

Upper-airway collapsibility and loop gain predict the response to oral appliance therapy in patients with obstructive sleep apnea

Edwards, B. A., Andara, C., Landry, S., Sands, S. A., Joosten, S. A., Owens, R. L., White, D. P., Hamilton, G. S. & Wellman, A., 1 Dec 2016, In : American Journal of Respiratory and Critical Care Medicine. 194, 11, p. 1413-1422 10 p.

Research output: Contribution to journal › Article › Research › peer-review

2015

An integrative model of physiological traits can be used to predict obstructive sleep apnea and response to non positive airway pressure therapy

Owens, R. L., Edwards, B. A., Eckert, D. J., Jordan, A. S., Sands, S. A., Malhotra, A., White, D. P., Loring, S. H., Butler, J. P. & Wellman, A., 1 Jun 2015, In : Sleep. 38, 6, p. 961-970 10 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

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Open Access

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2014

Acetazolamide attenuates hunter-cheyne-stokes breathing but augments the hypercapnic ventilatory response in patients with heart failure

Javaheri, S., Sands, S. A. & Edwards, B. A., 1 Jan 2014, In : Annals of the American Thoracic Society. 11, 1, p. 80-86 7 p.

Research output: Contribution to journal › Article › Research › peer-review

Blood pressure improvement with continuous positive airway pressure is independent of obstructive sleep apnea severity

Bakker, J. P., Edwards, B. A., Gautam, S. P., Montesi, S. B., Durán-Cantolla, J., Barandiarán, F. A., Barbé, F., Sańchez-De-La-Torre, M. & Malhotra, A., 2014, In : Journal of Clinical Sleep Medicine. 10, 4, p. 365-369 5 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep apnea

Edwards, B. A., Eckert, D. J., McSharry, D. G., Sands, S., Desai, A., Kehlmann, G., Bakker, J. P., Genta, P. R., Owens, R. L., White, D. P., Wellman, A. & Malhotra, A., 2014, In : American Journal of Respiratory and Critical Care Medicine. 190, 11, p. 1293 - 1300 8 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Enhanced upper-airway muscle responsiveness is a distinct feature of overweight/obese individuals without sleep apnea

Sands, S. A., Eckert, D. J., Jordan, A. S., Edwards, B. A., Owens, R. L., Butler, J. P., Schwab, R. J., Loring, S. H., Malhotra, A., White, D. P. & Wellman, A., 15 Oct 2014, In : American Journal of Respiratory and Critical Care Medicine. 190, 8, p. 930-937 8 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Erratum: Blood pressure improvement with continuous positive airway pressure is independent of obstructive sleep apnea severity (Journal of Clinical Sleep Medicine (2014) 10, 4 (365-369))

Bakker, J. P., Edwards, B. A., Gautam, S. P., Montesi, S. B., Durán-Cantolla, J., Aizpuru, F., Barbé, F., Sánchezde-la-Torre, M. & Malhotra, A., 2014, In : Journal of Clinical Sleep Medicine. 10, 6, p. 711 1 p.

Research output: Contribution to journal › Comment / Debate › Other › peer-review

Influence of pharyngeal muscle activity on inspiratory negative effort dependence in the human upper airway

Genta, P. R., Owens, R. L., Edwards, B. A., Sands, S. A., Eckert, D. J., Butler, J. P., Loring, S. H., Malhotra, A., Jackson, A. C., White, D. P. & Wellman, A., 15 Sep 2014, In : Respiratory Physiology and Neurobiology. 201, p. 55-59 5 p.

Research output: Contribution to journal › Article › Research › peer-review

Model-based estimation of loop gain using spontaneous breathing: A validation study

Gederi, E., Nemati, S., Edwards, B. A., Clifford, G. D., Malhotra, A. & Wellman, A., 15 Sep 2014, In : Respiratory Physiology and Neurobiology. 201, p. 84-92 9 p.

Research output: Contribution to journal › Article › Research › peer-review