Projects per year
Personal profile
Biography
Associate Professor Bing Hui Wang trained in Chemistry (BSc and MSc) and gained a PhD in the Department of Biochemistry, at La Trobe University. Associate Professor Wang is a world-leading researcher in the fields of heart failure and cardiorenal syndrome and has made a well-recognised contribution to the identification of novel biomarkers for diagnosis and therapeutic targets for drug development. His career has seen him work in both academic research in Australia and China, and commercial research in the biotechnology industry in Melbourne. He has made a significant contribution to academic research in the areas of his expertise, particularly in pathological mechanisms of inflammatory cytokines and mediators underpinning cardiovascular and related diseases such as heart failure and renal diseases.
Bing has expertise in molecular cell biology, biomarkers, and protein biochemistry, drug design, discovery and development, and pharmacology. He has a major interest in aiming to identify novel therapeutic targets for drug development through understanding the mechanisms underlying cardiovascular and related diseases. His current research areas include the pharmacology of cardiovascular diseases (CVDs), novel therapeutics for CVDs, drug discovery and development, and biomarker discovery and development. In particular, A/Prof Wang’s research is focused on the pathophysiology underpinning heart failure with preserved ejection fraction and cardiovascular and related diseases.
He has received funding from NHMRC, MRFF, and the National Heart Fund (NHF) for a number of research projects and new drug development. He has published more than 110 papers in major international journals including Circulation; European Heart J.; JAMA; Circ Heart Failure; Circ Res.; Am J. Physiol. Heart and Circ.; Intl J Cardiol.; Cardiovasc Ther. And Cardiovasc Res.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biochemistry and Chemistry, PhD, La Trobe University
1 Feb 1993 → 1 Jul 1996
Award Date: 1 Jul 1996
External positions
Associate Professor and Lab Head, Baker Heart and Diabetes Institute
12 Dec 2018 → …
Research area keywords
- Molecular biology
- Cellular biology
- Biomarkers
- Protein biochemistry
- Drug design and development
- Natural products chemistry
- Pharmacology
- Cardiovascular diseases
- Renal diseases
- Heart failure
- heart failure therapeutics
Collaborations and top research areas from the last five years
Projects
- 19 Finished
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Dihydroceramide Desaturase-1 (Des1) Inhibitors for the Treatment of Fibrotic Disease
Flynn, B. (Primary Chief Investigator (PCI)), Kelly, D. (Chief Investigator (CI)), Wang, B. (Chief Investigator (CI)), Reid, C. (Chief Investigator (CI)) & Pitson, S. M. (Chief Investigator (CI))
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/12/22
Project: Research
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The STAREE Heart Study
Hopper, I. (Primary Chief Investigator (PCI)), Zoungas, S. (Associate Investigator (AI)), Kaye, D. (Associate Investigator (AI)), Reid, C. (Associate Investigator (AI)), McNeil, J. (Associate Investigator (AI)), Wang, B. (Associate Investigator (AI)), Freedman, B. (Associate Investigator (AI)), Marwick, T. H. (Associate Investigator (AI)) & Tonkin, A. (Associate Investigator (AI))
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/12/23
Project: Research
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Development and evaluation of a eHealth 'Virtual Hospital' to improve the care of patients with chronic diseases.
Liew, D. (Primary Chief Investigator (PCI)), Sievert, W. (Chief Investigator (CI)), Cameron, J. (Chief Investigator (CI)), Le, S. T. T. (Chief Investigator (CI)), Wang, B. (Chief Investigator (CI)), St John, H. (Chief Investigator (CI)), Whittle, J. (Chief Investigator (CI)), Larkins, A. (Chief Investigator (CI)) & Flynn, D. (Chief Investigator (CI))
1/09/18 → 29/02/20
Project: Research
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Targeting the Aryl Hydrocarbon Receptor in Cardiorenal Syndrome
Kompa, A. (Primary Chief Investigator (PCI)), Wang, B. (Chief Investigator (CI)), Zhang, Y. (Chief Investigator (CI)), Langham, R. (Chief Investigator (CI)) & Kelly, D. (Associate Investigator (AI))
16/01/17 → 16/04/18
Project: Research
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Bone Biomarkers, PINP and CTX I, analysis
Wang, B. (Primary Chief Investigator (PCI))
3/01/17 → 30/06/17
Project: Research
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Novel small-molecule compound VCP979 attenuates renal fibrosis in male rats with unilateral ureteral obstruction
Min, S., Chang, D., Wang, Y. C., Xu, T. T., Ge, H., Zhang, J., Wang, B. & Ju, S., Feb 2023, In: Experimental Biology and Medicine. 248, 4, p. 327-338 12 p.Research output: Contribution to journal › Article › Research › peer-review
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A randomised preclinical trial of adrenaline use during cardiac arrest in mice
Donner, D. G., Bloom, J. E., Shihata, W. A., Brown, A. A., Cook, R., Yee Tai, T., Lambert, G. W., Chu, P.-Y., Chan, W., Stub, D., Wang, B. H. & Kaye, D. M., Sept 2022, In: Resuscitation Plus. 11, 6 p., 100292.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Characterization of Cardiac Sympathetic Nervous System and Inflammatory Activation in HFpEF Patients
Kaye, D. M., Nanayakkara, S., Wang, B., Shihata, W., Marques, F. Z., Esler, M., Lambert, G. & Mariani, J., Feb 2022, In: JACC: Basic to Translational Science. 7, 2, p. 116-127 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access34 Citations (Scopus) -
Effect of upstream doxycycline during primary percutaneous coronary intervention for st elevation myocardial infarction on infarct size and left ventricular remodelling, a randomized clinical trial
Noaman, S., Neil, C., O'Brien, J., Wang, B., YeeTai, T., Frenneaux, M. P., Hare, J. L., Gay, A., Shaw, J., Stub, D., Bloom, J., Walton, A., Duffy, S., Peter, K.-H., Cox, N., Kaye, D. M., Taylor, A. J. & Chan, W., Mar 2022, In: Journal of the American College of Cardiology. 79, 9, 1 p., 3484.Research output: Contribution to journal › Meeting Abstract › peer-review
Open Access -
Physiologic Insights Into Long COVID Breathlessness
Kaye, D. M., Vizi, D., Graham, S., Wang, B., Shihata, W., Nanayakkara, S., Mariani, J. & Premaratne, M., 1 Jun 2022, In: Circulation: Heart Failure. 15, 6, p. 627-628 2 p., E009346.Research output: Contribution to journal › Letter › Other › peer-review
Activities
- 1 Patents
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Southeast University (Jiangsu, China) (External organisation)
Wang Guangjing (Inventor), Henry Krum (Inventor), Bing Wang (Inventor), Ling Xia (Inventor) & Xingqun Zhao (Inventor)
9 Oct 2013Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent