Projects per year
Personal profile
Biography
Dr Bing Hui Wang trained in Chemistry (BSc and MSc) and gained a PhD in the Department of Biochemistry, La Trobe University. His post-doctoral research has been in the area of cellular signaling in cardiac vascular diseases. He was a senior research officer at the Baker Heart Research Institute for four years and involved in studies on the roles of adrenergic receptors in cardiac function and discovered inositol polyphosphate 1-phosphatase as a novel anti-hypertrophic factor.
He then changed his career to commercial research in biotechnology industry. During his research as the Senior Scientist and Head of the Molecular Biology Department, at Cytopia Pty Ltd he made substantial contributions to many of the patents and other intellectual properties.
In October, 2005, Dr Wang re-joined academic research by taking up a Senior Research Fellow position with Prof Henry Krum, Centre of Cardiovascular Research and Education in Therapeutics, Department of Epidemiology and Preventive Medicine, Monash University. Under the mentorship of Prof Krum, Dr Wang has made significant progress and contribution to academic research in the areas of cardiovascular pharmacology, drug discovery and development, and cardiorenal syndrome research. Dr Wang has expertise in molecular and cellular biology, biomarkers and protein biochemistry, drug design and development, natural products chemistry and pharmacology, especially in signaling mechanisms of inflammatory cytokines and mediators/biomarkers in cardiovascular and renal diseases including heart failure and chronic kidney diseases.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biochemistry and Chemistry, PhD, La Trobe University
1 Feb 1993 → 1 Jul 1996
Award Date: 1 Jul 1996
Research area keywords
- Molecular biology
- Cellular biology
- Biomarkers
- Protein biochemistry
- Drug design and development
- Natural products chemistry
- Pharmacology
- Cardiovascular diseases
- Renal diseases
Network
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The STAREE Heart Study
Hopper, I., Zoungas, S., Kaye, D., Reid, C., McNeil, J., Wang, B., Freedman, B., Marwick, T. H. & Tonkin, A.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/12/23
Project: Research
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Dihydroceramide Desaturase-1 (Des1) Inhibitors for the Treatment of Fibrotic Disease
Flynn, B., Kelly, D., Wang, B., Reid, C. & Pitson, S. M.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/12/22
Project: Research
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Development and evaluation of a eHealth 'Virtual Hospital' to improve the care of patients with chronic diseases.
Liew, D., Sievert, W., Cameron, J., Le, S. T. T., Wang, B., St John, H., Whittle, J., Larkins, A. & Flynn, D.
1/09/18 → 29/02/20
Project: Research
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Targeting the Aryl Hydrocarbon Receptor in Cardiorenal Syndrome
Kompa, A., Wang, B., Zhang, Y., Langham, R. & Kelly, D.
16/01/17 → 16/04/18
Project: Research
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Apoptosis signal-regulating kinase 1 inhibition reverses deleterious indoxyl sulfate-mediated endothelial effects
Savira, F., Kompa, A. R., Magaye, R., Xiong, X., Huang, L., Jucker, B. M., Willette, R. N., Kelly, D. J. & Wang, B. H., 1 May 2021, In: Life Sciences. 272, 9 p., 119267.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells
Magaye, R. R., Savira, F., Hua, Y., Xiong, X., Huang, L., Reid, C., Flynn, B. L., Kaye, D., Liew, D. & Wang, B. H., May 2021, In: International Journal of Biochemistry & Cell Biology. 134, 16 p., 105952.Research output: Contribution to journal › Article › Research › peer-review
6 Citations (Scopus) -
Cost-effectiveness of dapagliflozin in chronic heart failure: an analysis from the Australian healthcare perspective
Savira, F., Wang, B. H., Kompa, A. R., Ademi, Z., Owen, A. J., Zoungas, S., Tonkin, A., Liew, D. & Zomer, E., Sep 2021, In: European Journal of Preventive Cardiology. 28, 9, p. 975-982 8 p.Research output: Contribution to journal › Article › Research › peer-review
13 Citations (Scopus) -
Dihydrosphingosine driven enrichment of sphingolipids attenuates TGFβ induced collagen synthesis in cardiac fibroblasts
Magaye, R. R., Savira, F., Xiong, X., Huynh, K., Meikle, P. J., Reid, C., Flynn, B. L., Kaye, D., Liew, D. & Wang, B. H., Aug 2021, In: IJC Heart & Vasculature. 35, 11 p., 100837.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Effect of Intra-Articular Platelet-Rich Plasma vs Placebo Injection on Pain and Medial Tibial Cartilage Volume in Patients with Knee Osteoarthritis: The RESTORE Randomized Clinical Trial
Bennell, K. L., Paterson, K. L., Metcalf, B. R., Duong, V., Eyles, J., Kasza, J., Wang, Y., Cicuttini, F., Buchbinder, R., Forbes, A., Harris, A., Yu, S. P., Connell, D., Linklater, J., Wang, B. H., Oo, W. M. & Hunter, D. J., 30 Nov 2021, In: JAMA: Journal of the American Medical Association. 326, 20, p. 2021-2030 10 p.Research output: Contribution to journal › Article › Research › peer-review
15 Citations (Scopus)
Activities
- 1 Patents
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Southeast University (External organisation)
Wang Guangjing (Inventor), Henry Krum (Inventor), Bing Wang (Inventor), Ling Xia (Inventor) & Xingqun Zhao (Inventor)
9 Oct 2013Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent