Projects per year
Personal profile
Biography
Dr Bing Hui Wang trained in Chemistry (BSc and MSc) and gained a PhD in the Department of Biochemistry, La Trobe University. His post-doctoral research has been in the area of cellular signaling in cardiac vascular diseases. He was a senior research officer at the Baker Heart Research Institute for four years and involved in studies on the roles of adrenergic receptors in cardiac function and discovered inositol polyphosphate 1-phosphatase as a novel anti-hypertrophic factor.
He then changed his career to commercial research in biotechnology industry. During his research as the Senior Scientist and Head of the Molecular Biology Department, at Cytopia Pty Ltd he made substantial contributions to many of the patents and other intellectual properties.
In October, 2005, Dr Wang re-joined academic research by taking up a Senior Research Fellow position with Prof Henry Krum, Centre of Cardiovascular Research and Education in Therapeutics, Department of Epidemiology and Preventive Medicine, Monash University. Under the mentorship of Prof Krum, Dr Wang has made significant progress and contribution to academic research in the areas of cardiovascular pharmacology, drug discovery and development, and cardiorenal syndrome research. Dr Wang has expertise in molecular and cellular biology, biomarkers and protein biochemistry, drug design and development, natural products chemistry and pharmacology, especially in signaling mechanisms of inflammatory cytokines and mediators/biomarkers in cardiovascular and renal diseases including heart failure and chronic kidney diseases.
Education/Academic qualification
Biochemistry and Chemistry, PhD, La Trobe University
1 Feb 1993 → 1 Jul 1996
Award Date: 1 Jul 1996
Network
Projects
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The STAREE Heart Study
Hopper, I., Zoungas, S., Kaye, D., Reid, C., McNeil, J., Wang, B., Freedman, B., Marwick, T. H. & Tonkin, A.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/12/23
Project: Research
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Dihydroceramide Desaturase-1 (Des1) Inhibitors for the Treatment of Fibrotic Disease
Flynn, B., Kelly, D., Wang, B., Reid, C. & Pitson, S.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/19 → 31/12/21
Project: Research
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Development and evaluation of a eHealth 'Virtual Hospital' to improve the care of patients with chronic diseases.
Liew, D., Sievert, W., Cameron, J., Le, S. T. T., Wang, B., St John, H., Whittle, J., Larkins, A. & Flynn, D.
1/09/18 → 29/02/20
Project: Research
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Targeting the Aryl Hydrocarbon Receptor in Cardiorenal Syndrome
Kompa, A., Wang, B., Zhang, Y., Langham, R. & Kelly, D.
16/01/17 → 16/04/18
Project: Research
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Research output
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A novel small molecule compound VCP979 improves ventricular remodeling in murine models of myocardial ischemia/reperfusion injury
Liu, J., Meng, Q., Liang, X., Zhuang, R., Yuan, D., Ge, X., Cao, H., Lin, F., Gong, X., Fan, H., Wang, B., Zhou, X. & Liu, Z., Feb 2020, In : International Journal of Molecular Medicine. 45, 2, p. 353-364 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile -
Cardiorenal syndrome: Multi-organ dysfunction involving the heart, kidney and vasculature
Savira, F., Magaye, R., Liew, D., Reid, C., Kelly, D. J., Kompa, A. R., Sangaralingham, S. J., Burnett, J. C., Kaye, D. & Wang, B. H., Jul 2020, In : British Journal of Pharmacology. 177, 13, p. 2906-2922 17 p.Research output: Contribution to journal › Review Article › Research › peer-review
4 Citations (Scopus) -
Cost-effectiveness of dapagliflozin in chronic heart failure: an analysis from the Australian healthcare perspective
Savira, F., Wang, B. H., Kompa, A. R., Ademi, Z., Owen, A. J., Zoungas, S., Tonkin, A., Liew, D. & Zomer, E., 2020, (Accepted/In press) In : European Journal of Preventive Cardiology. 10 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Cost-effectiveness of switching patients with heart failure and reduced ejection fraction to sacubitril/valsartan: The Australian perspective
Chin, K. L., Zomer, E., Wang, B. & Liew, D., Sep 2020, In : Heart Lung and Circulation. 29, 9, p. 1310-1317 8 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Exogenous dihydrosphingosine 1 phosphate mediates collagen synthesis in cardiac fibroblasts through JAK/STAT signalling and regulation of TIMP1
Magaye, R. R., Savira, F., Hua, Y., Xiong, X., Huang, L., Reid, C., Flynn, B., Kaye, D., Liew, D. & Wang, B. H., Aug 2020, In : Cellular Signalling. 72, 18 p., 109629.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus)