Bimbil Graham

Assoc Professor

19972018
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Personal profile

Research interests

Dr Graham's research is focussed on the development of novel conjugatable reagents and their use in protein labelling, as well as the construction of bioconjugates for a range of analytical, imaging and therapeutic applications. Major projects include the development of:

  • Chemical tools to facilitate advanced biomolecular NMR and EPR spectroscopic studies
  • Luminescent probes to study GPCR pharmacology

 

Monash teaching commitment

  • Bioorganic and Medicinal Chemistry I and II (unit coordinator and lecturer)
  • Chemical Technologies for the Pharmaceutical Sciences (lecturer)

Keywords

  • Synthetic Chemistry
  • Coordination Chemistry
  • Bioconjugation

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Projects 2009 2017

Research Output 1997 2018

8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase

Dennis, M. L., Lee, M. D., Harjani, J. R., Ahmed, M., Debono, A. J., Pitcher, N. P., Wang, Z-C., Chhabra, S., Barlow, N., Rahmani, R., Cleary, B., Dolezal, O., Hattarki, M., Aurelio, L., Shonberg, J., Graham, B., Peat, T. S., Baell, J. B. & Swarbrick, J. D., 6 Feb 2018, In : Chemistry - A European Journal. 24, 8, p. 1922-1930 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Fluorescently Labeled Morphine Derivatives for Bioimaging Studies

Lam, R., Gondin, A. B., Canals, M., Kellam, B., Briddon, S. J., Graham, B. & Scammells, P. J., 8 Feb 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 1316-1329 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Genetically encoded amino acids with tert-butyl and trimethylsilyl groups for site-selective studies of proteins by NMR spectroscopy

Loh, C. T., Adams, L. A., Graham, B. & Otting, G., 1 Aug 2018, In : Journal of Biomolecular NMR. 71, 4, p. 287-293 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Lanthanide complexes for luminescence-based sensing of low molecular weight analytes

Aulsebrook, M. L., Graham, B., Grace, M. R. & Tuck, K. L., 2018, (Accepted/In press) In : Coordination Chemistry Reviews. 30 p.

Research output: Contribution to journalArticleResearchpeer-review

Modified Gold Nanoparticles for the Temperature-Dependent Colorimetric Detection of Mercury and Methylmercury

Aulsebrook, M. L., Watkins, E., Grace, M. R., Graham, B. & Tuck, K. L., 21 Feb 2018, In : ChemistrySelect. 3, 7, p. 2088-2091 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Activities 2011 2011

  • 1 Submissions to industry or govt committees, commissions and inquiries

Medicinal Chemistry and Drug Action

Bimbil Graham (Member)
25 Nov 2011

Activity: External Academic EngagementSubmissions to industry or govt committees, commissions and inquiries