20032020

Research output per year

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Research Output

2019

The NUP98-HOXD13 fusion oncogene induces thymocyte self-renewal via Lmo2/Lyl1

Shields, B. J., Slape, C. I., Vo, N., Jackson, J. T., Pliego-Zamora, A., Ranasinghe, H., Shi, W., Curtis, D. J. & McCormack, M. P., 1 Jan 2019, In : Leukemia. 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
2018

Analysis of histone modifications in acute myeloid leukaemia using chromatin immunoprecipitation

Shields, B. J., Keniry, A., Blewitt, M. E. & McCormack, M. P., 1 Jan 2018, Inflammation and Cancer: Methods and Protocols. Jenkins, B. J. (ed.). New York : Humana Press, p. 177-184 8 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

1 Citation (Scopus)

Hhex induces promyelocyte self-renewal and cooperates with growth factor independence to cause myeloid leukemia in mice

Jackson, J. T., Ng, A., Shields, B. J., Haupt, S. M., Haupt, Y. & McCormack, M. P., 27 Feb 2018, In : Blood Advances. 2, 4, p. 347-360 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)
2017

Hhex Regulates Hematopoietic Stem Cell Self-Renewal and Stress Hematopoiesis via Repression of Cdkn2a

Jackson, J. T., Shields, B. J., Shi, W., Di Rago, L., Metcalf, D., Nicola, N. A. & Mccormack, M. P., Aug 2017, In : Stem Cells. 35, 8, p. 1948-1957 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)
2016

Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a

Shields, B., Jackson, J. T., Metcalf, D., Shi, W., Huang, Q., Garnham, A. L., Glaser, S. P., Beck, D., Pimanda, J. E., Bogue, C. W., Smyth, G. K., Alexander, W. S. & McCormack, M. P., 1 Jan 2016, In : Genes and Development. 30, 1, p. 78-91 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
14 Citations (Scopus)
2015

Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2-transgenic mice

Shields, B., Alserihi, R., Nasa, C., Bogue, C., Alexander, W. S. & McCormack, M. P., 15 Apr 2015, In : Leukemia. 29, 4, p. 927-938 12 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)
2013

Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL

McCormack, M., Shields, B., Jackson, J., Nasa, C., Shi, W., Slater, N. J., Tremblay, C., Rabbitts, T. H. & Curtis, D. J., 2013, In : Blood. 122, 12, p. 2093 - 2103 11 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers

Shields, B., Wiede, F., Gurzov, E., Wee, K. T. B., Hauser, C., Zhu, H-J., Molloy, T. J., O'Toole, S. A., Daly, R. J., Sutherland, R. L., Mitchell, C. A., McLean, C. A. & Tiganis, T., 2013, In : Molecular and Cellular Biology. 33, 3, p. 557 - 570 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
51 Citations (Scopus)
2011

T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice

Wiede, F., Shields, B., Chew, K. S. H., Kyparissoudis, K., van Vliet, C. J., Galic, S., Tremblay, M. L., Russell, S. M., Godfrey, D. I. & Tiganis, T., 2011, In : Journal of Clinical Investigation. 121, 12, p. 4758 - 4774 17 p.

Research output: Contribution to journalArticleResearchpeer-review

111 Citations (Scopus)
2010

Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

Fedele, C. G., Ooms, L. M., Ho, M., Vieusseux, J. L., O'Toole, S. A., Millar, E. K., Lopez-Knowles, E., Sriratana, A., Gurung, R., Baglietto, L., Giles, G., Bailey, C. G., Rasko, J. EJ., Shields, B. J., Price, J. T., Majerus, P. W., Sutherland, R. L., Tiganis, T., McLean, C. A. & Mitchell, C. A., 2010, In : Proceedings of the National Academy of Sciences. 107, 51, p. 22231 - 22236 6 p.

Research output: Contribution to journalArticleResearchpeer-review

171 Citations (Scopus)

T-cell protein tyrosine phosphatase attenuates STAT3 and insulin signaling in the liver to regulate gluconeogenesis

Fukushima, A., Loh, K., Galic, S., Fam, B., Shields, B., Wiede, F., Tremblay, M. L., Watt, M. J., Andrikopoulos, S. & Tiganis, T., 2010, In : Diabetes. 59, 8, p. 1906 - 1914 9 p.

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)
2009

Reactive oxygen species enhance insulin sensitivity

Loh, K. Y., Deng, H., Fukushima, A., Cai, X., Boivin, B., Galic, S., Bruce, C., Shields, B. J., Skiba, B., Ooms, L. M., Stepto, N. K., Wu, B. J., Mitchell, C. A., Tonks, N. K., Watt, M. J., Febbraio, M. A., Crack, P. J., Andrikopoulos, S. & Tiganis, T., 2009, In : Cell Metabolism. 10, 4, p. 260 - 272 13 p.

Research output: Contribution to journalArticleResearchpeer-review

368 Citations (Scopus)

Replication checkpoint control by a PTK/STAT3/cyclin D1 axis

Shields, B. J. & Tiganis, T., 2009, In : Cell Cycle. 8, 2, p. 223 - 230 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)
2008

Cell cycle-dependent regulation of SFK, JAK1 and STAT3 signalling by the protein tyrosine phosphatase TCPTP

Shields, B. J., Court, N. W., Hauser, C., Bukczynska, P. E. & Tiganis, T., 2008, In : Cell Cycle. 7, 21, p. 3405 - 3416 12 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

DNA replication stalling attenuates tyrosine kinase signaling to suppress S phase progression

Shields, B. J., Hauser, C., Bukczynska, P. E., Court, N. W. & Tiganis, T., 2008, In : Cancer Cell. 14, 2, p. 166 - 179 14 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling

Lu, X., Malumbres, R., Shields, B. J., Jiang, X., Sarosiek, K. A., Natkunam, Y., Tiganis, T. & Lossos, I. S., 2008, In : Blood. 112, 10, p. 4098 - 4108 11 p.

Research output: Contribution to journalArticleResearchpeer-review

82 Citations (Scopus)
2005

Interaction between the respiratory syncytial virus G glycoprotein cytoplasmic domain and the matrix protein

Ghildyal, R., Li, D., Peroulis, I., Shields, B. J., Bardin, P. G., Teng, M. N., Collins, P. L., Meanger, J. & Mills, J., 2005, In : Journal of General Virology. 86, 7, p. 1879 - 1884 6 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase

van Vliet, C. J., Bukczynska, P. E., Puryer, M. A., Sadek, C. M., Shields, B. J., Tremblay, M. L. & Tiganis, T., 2005, In : Nature Immunology. 6, 3, p. 253 - 260 8 p.

Research output: Contribution to journalArticleResearchpeer-review

126 Citations (Scopus)
2004

Association of matrix protein of respiratory syncytial virus with the host cell membrane of infected cells (Brief Report)

Marty, A., Meander, J., Mills, J., Shields, B. & Ghildyal, R., 2004, In : Archives of Virology. 149, p. 199 - 210 12 p.

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)
2003

Multiple heparin binding domains of respiratory syncytial virus G mediate binding to mammalian cells

Shields, B., Mills, J., Ghildyal, R., Gooley, P. & Meanger, J., 2003, In : Archives of Virology. 148, 10, p. 1987 - 2003 17 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)